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Items: 27


CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data.

Wegmann R, Neri M, Schuierer S, Bilican B, Hartkopf H, Nigsch F, Mapa F, Waldt A, Cuttat R, Salick MR, Raymond J, Kaykas A, Roma G, Keller CG.

Genome Biol. 2019 Jul 17;20(1):142. doi: 10.1186/s13059-019-1739-7.


Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection.

Wells MF, Salick MR, Wiskow O, Ho DJ, Worringer KA, Ihry RJ, Kommineni S, Bilican B, Klim JR, Hill EJ, Kane LT, Ye C, Kaykas A, Eggan K.

Cell Stem Cell. 2016 Dec 1;19(6):703-708. doi: 10.1016/j.stem.2016.11.011.


Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, Simpson TI, Tybulewicz VL, Wyllie DJ, Fisher EM, Lowell S, Chandran S, Hardingham GE.

Elife. 2016 Oct 1;5. pii: e20337. doi: 10.7554/eLife.20337.


Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2.

Bell KF, Al-Mubarak B, Martel MA, McKay S, Wheelan N, Hasel P, Márkus NM, Baxter P, Deighton RF, Serio A, Bilican B, Chowdhry S, Meakin PJ, Ashford ML, Wyllie DJ, Scannevin RH, Chandran S, Hayes JD, Hardingham GE.

Nat Commun. 2015 May 13;6:7066. doi: 10.1038/ncomms8066.


Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones.

James OT, Livesey MR, Qiu J, Dando O, Bilican B, Haghi G, Rajan R, Burr K, Hardingham GE, Chandran S, Kind PC, Wyllie DJ.

J Physiol. 2014 Oct 1;592(19):4353-63. doi: 10.1113/jphysiol.2014.278994. Epub 2014 Aug 28.


Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.

Barmada SJ, Serio A, Arjun A, Bilican B, Daub A, Ando DM, Tsvetkov A, Pleiss M, Li X, Peisach D, Shaw C, Chandran S, Finkbeiner S.

Nat Chem Biol. 2014 Aug;10(8):677-85. doi: 10.1038/nchembio.1563. Epub 2014 Jun 29.


Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells.

Nishimura AL, Shum C, Scotter EL, Abdelgany A, Sardone V, Wright J, Lee YB, Chen HJ, Bilican B, Carrasco M, Maniatis T, Chandran S, Rogelj B, Gallo JM, Shaw CE.

PLoS One. 2014 Mar 20;9(3):e91269. doi: 10.1371/journal.pone.0091269. eCollection 2014.


Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons.

Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJ.

J Neurosci. 2014 Mar 12;34(11):4070-5. doi: 10.1523/JNEUROSCI.5410-13.2014.


Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.

Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SSW, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, Shaw CE, Eggan KC, Maniatis T, Taylor JP.

Neuron. 2014 Feb 5;81(3):536-543. doi: 10.1016/j.neuron.2013.12.018.


Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells.

Bilican B, Livesey MR, Haghi G, Qiu J, Burr K, Siller R, Hardingham GE, Wyllie DJ, Chandran S.

PLoS One. 2014 Jan 17;9(1):e85932. doi: 10.1371/journal.pone.0085932. eCollection 2014.


High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology.

Stacpoole SR, Spitzer S, Bilican B, Compston A, Karadottir R, Chandran S, Franklin RJ.

Stem Cell Reports. 2013 Oct 31;1(5):437-50. doi: 10.1016/j.stemcr.2013.09.006. eCollection 2013.


Using human induced pluripotent stem cells to treat retinal disease.

Borooah S, Phillips MJ, Bilican B, Wright AF, Wilmut I, Chandran S, Gamm D, Dhillon B.

Prog Retin Eye Res. 2013 Nov;37:163-81. doi: 10.1016/j.preteyeres.2013.09.002. Epub 2013 Oct 6. Review.


Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.

Bilican B, Serio A, Shaw CE, Maniatis T, Chandran S.

Cell Cycle. 2013 Aug 1;12(15):2339-40. doi: 10.4161/cc.25705. Epub 2013 Jul 11. No abstract available.


Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Sci Transl Med. 2013 Jun 5;5(188):188le2. doi: 10.1126/scitranslmed.3005065.


Neural precursor cells cultured at physiologically relevant oxygen tensions have a survival advantage following transplantation.

Stacpoole SR, Webber DJ, Bilican B, Compston A, Chandran S, Franklin RJ.

Stem Cells Transl Med. 2013 Jun;2(6):464-72. doi: 10.5966/sctm.2012-0144. Epub 2013 May 15.


Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, Shaw CE, Finkbeiner S, Chandran S.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4697-702. doi: 10.1073/pnas.1300398110. Epub 2013 Feb 11.


Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26.


Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen.

Stacpoole SR, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, Franklin RJ, Chandran S.

Nat Protoc. 2011 Jul 28;6(8):1229-40. doi: 10.1038/nprot.2011.380.


Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation.

Stacpoole SR, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, Franklin RJ, Chandran S.

Cell Death Differ. 2011 Jun;18(6):1016-23. doi: 10.1038/cdd.2010.171. Epub 2011 Jan 28.


Cell-mediated neuroprotection in a mouse model of human tauopathy.

Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MG, Chandran S.

J Neurosci. 2010 Jul 28;30(30):9973-83. doi: 10.1523/JNEUROSCI.0834-10.2010.


Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.

Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A, Pedersen RA.

Stem Cells. 2009 Nov;27(11):2655-66. doi: 10.1002/stem.199.


Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level.

Bilican B, Fiore-Heriche C, Compston A, Allen ND, Chandran S.

PLoS One. 2008 Aug 6;3(8):e2863. doi: 10.1371/journal.pone.0002863.


Ectopic Tbx2 expression results in polyploidy and cisplatin resistance.

Davis E, Teng H, Bilican B, Parker MI, Liu B, Carriera S, Goding CR, Prince S.

Oncogene. 2008 Feb 7;27(7):976-84. Epub 2007 Aug 13.


T-box factors: targeting to chromatin and interaction with the histone H3 N-terminal tail.

Demay F, Bilican B, Rodriguez M, Carreira S, Pontecorvi M, Ling Y, Goding CR.

Pigment Cell Res. 2007 Aug;20(4):279-87.


Cell cycle regulation of the T-box transcription factor tbx2.

Bilican B, Goding CR.

Exp Cell Res. 2006 Jul 15;312(12):2358-66. Epub 2006 May 6.


Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination.

Erdemir T, Bilican B, Cagatay T, Goding CR, Yavuzer U.

Mol Microbiol. 2002 Nov;46(4):947-57.


DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).

Erdemir T, Bilican B, Oncel D, Goding CR, Yavuzer U.

J Cell Sci. 2002 Jan 1;115(Pt 1):207-16.

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