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Items: 1 to 50 of 77

1.

Quantifying the Infectiousness of Post-Kala-Azar Dermal Leishmaniasis Toward Sand Flies.

Mondal D, Bern C, Ghosh D, Rashid M, Molina R, Chowdhury R, Nath R, Ghosh P, Chapman LAC, Alim A, Bilbe G, Alvar J.

Clin Infect Dis. 2019 Jul 2;69(2):251-258. doi: 10.1093/cid/ciy891.

2.

Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.

Alves F, Bilbe G, Blesson S, Goyal V, Monnerat S, Mowbray C, Muthoni Ouattara G, Pécoul B, Rijal S, Rode J, Solomos A, Strub-Wourgaft N, Wasunna M, Wells S, Zijlstra EE, Arana B, Alvar J.

Clin Microbiol Rev. 2018 Aug 29;31(4). pii: e00048-18. doi: 10.1128/CMR.00048-18. Print 2018 Oct. Review.

PMID:
30158301
3.

Infectious diseases. Overcoming neglect of kinetoplastid diseases.

Bilbe G.

Science. 2015 May 29;348(6238):974-6. doi: 10.1126/science.aaa3683. Epub 2015 May 28. No abstract available.

PMID:
26023124
4.

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation.

Feuerbach D, Pezous N, Weiss M, Shakeri-Nejad K, Lingenhoehl K, Hoyer D, Hurth K, Bilbe G, Pryce CR, McAllister K, Chaperon F, Kucher K, Johns D, Blaettler T, Lopez Lopez C.

Br J Pharmacol. 2015 Mar;172(5):1292-304. doi: 10.1111/bph.13001. Epub 2015 Jan 12.

5.

AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization.

Vranesic I, Ofner S, Flor PJ, Bilbe G, Bouhelal R, Enz A, Desrayaud S, McAllister K, Kuhn R, Gasparini F.

Bioorg Med Chem. 2014 Nov 1;22(21):5790-803. doi: 10.1016/j.bmc.2014.09.033. Epub 2014 Sep 20.

PMID:
25316499
6.

Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.

Weiss A, Träger U, Wild EJ, Grueninger S, Farmer R, Landles C, Scahill RI, Lahiri N, Haider S, Macdonald D, Frost C, Bates GP, Bilbe G, Kuhn R, Andre R, Tabrizi SJ.

J Clin Invest. 2012 Oct;122(10):3731-6. doi: 10.1172/JCI64565. Epub 2012 Sep 17.

7.

The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in L-Dopa-treated parkinsonian monkeys.

Grégoire L, Morin N, Ouattara B, Gasparini F, Bilbe G, Johns D, Vranesic I, Sahasranaman S, Gomez-Mancilla B, Di Paolo T.

Parkinsonism Relat Disord. 2011 May;17(4):270-6. doi: 10.1016/j.parkreldis.2011.01.008. Epub 2011 Feb 15.

PMID:
21315648
8.

Optimization of an HTRF Assay for the Detection of Soluble Mutant Huntingtin in Human Buffy Coats: A Potential Biomarker in Blood for Huntington Disease.

Moscovitch-Lopatin M, Weiss A, Rosas HD, Ritch J, Doros G, Kegel KB, Difiglia M, Kuhn R, Bilbe G, Paganetti P, Hersch S.

PLoS Curr. 2010 Dec 29;2:RRN1205. doi: 10.1371/currents.RRN1205.

9.

Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.

Jacquemont S, Curie A, des Portes V, Torrioli MG, Berry-Kravis E, Hagerman RJ, Ramos FJ, Cornish K, He Y, Paulding C, Neri G, Chen F, Hadjikhani N, Martinet D, Meyer J, Beckmann JS, Delange K, Brun A, Bussy G, Gasparini F, Hilse T, Floesser A, Branson J, Bilbe G, Johns D, Gomez-Mancilla B.

Sci Transl Med. 2011 Jan 5;3(64):64ra1. doi: 10.1126/scitranslmed.3001708.

10.

Metabotropic glutamate receptor type 5 in levodopa-induced motor complications.

Ouattara B, Grégoire L, Morissette M, Gasparini F, Vranesic I, Bilbe G, Johns DR, Rajput A, Hornykiewicz O, Rajput AH, Gomez-Mancilla B, Di Paolo T.

Neurobiol Aging. 2011 Jul;32(7):1286-95. doi: 10.1016/j.neurobiolaging.2009.07.014. Epub 2009 Dec 29.

PMID:
20036444
11.

Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease.

Weiss A, Abramowski D, Bibel M, Bodner R, Chopra V, DiFiglia M, Fox J, Kegel K, Klein C, Grueninger S, Hersch S, Housman D, Régulier E, Rosas HD, Stefani M, Zeitlin S, Bilbe G, Paganetti P.

Anal Biochem. 2009 Dec 1;395(1):8-15. doi: 10.1016/j.ab.2009.08.001. Epub 2009 Aug 6.

PMID:
19664996
12.

The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain.

Feuerbach D, Lingenhoehl K, Olpe HR, Vassout A, Gentsch C, Chaperon F, Nozulak J, Enz A, Bilbe G, McAllister K, Hoyer D.

Neuropharmacology. 2009 Jan;56(1):254-63. doi: 10.1016/j.neuropharm.2008.08.025. Epub 2008 Aug 28.

PMID:
18793655
13.

mGluR5 antagonists: discovery, characterization and drug development.

Gasparini F, Bilbe G, Gomez-Mancilla B, Spooren W.

Curr Opin Drug Discov Devel. 2008 Sep;11(5):655-65. Review.

PMID:
18729017
14.

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis.

Dev KK, Mullershausen F, Mattes H, Kuhn RR, Bilbe G, Hoyer D, Mir A.

Pharmacol Ther. 2008 Jan;117(1):77-93. Epub 2007 Sep 8. Review.

PMID:
17961662
15.

Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders.

Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor P, VAN DER Putten H, Schmutz M, Bilbe G, Cryan JF.

J Recept Signal Transduct Res. 2006;26(5-6):527-47.

PMID:
17118797
16.

Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine.

Conti B, Maier R, Barr AM, Morale MC, Lu X, Sanna PP, Bilbe G, Hoyer D, Bartfai T.

Mol Psychiatry. 2007 Feb;12(2):167-89. Epub 2006 Oct 10.

PMID:
17033635
17.

At issue: A model for academic/industry collaboration.

Carpenter WT Jr, Koenig JI, Bilbe G, Bischoff S.

Schizophr Bull. 2004;30(4):997-1004.

PMID:
15954203
18.

Applications of a rat multiple tissue gene expression data set.

Walker JR, Su AI, Self DW, Hogenesch JB, Lapp H, Maier R, Hoyer D, Bilbe G.

Genome Res. 2004 Apr;14(4):742-9.

19.
20.

Distribution of type-1 and type-2 angiotensin receptors in the normal human lung and in lungs from patients with chronic obstructive pulmonary disease.

Bullock GR, Steyaert I, Bilbe G, Carey RM, Kips J, De Paepe B, Pauwels R, Praet M, Siragy HM, de Gasparo M.

Histochem Cell Biol. 2001 Feb;115(2):117-24.

PMID:
11444146
21.

Mouse models of alpha-synucleinopathy and Lewy pathology. Alpha-synuclein expression in transgenic mice.

Barbieri S, Hofele K, Wiederhold KH, Probst A, Mistl C, Danner S, Kauffmann S, Sommer B, Spooren W, Tolnay M, Bilbe G, van der Putten H.

Adv Exp Med Biol. 2001;487:147-67. Review. No abstract available.

PMID:
11403156
22.

Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling.

Bowler WB, Buckley KA, Gartland A, Hipskind RA, Bilbe G, Gallagher JA.

Bone. 2001 May;28(5):507-12. Review.

PMID:
11344050
23.

Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.

Buckley KA, Wagstaff SC, McKay G, Gaw A, Hipskind RA, Bilbe G, Gallagher JA, Bowler WB.

J Biol Chem. 2001 Mar 23;276(12):9565-71. Epub 2000 Dec 21.

24.

Mouse models of alpha-synucleinopathy and Lewy pathology.

Sommer B, Barbieri S, Hofele K, Wiederhold K, Probst A, Mistl C, Danner S, Kauffmann S, Spooren W, Tolnay M, Bilbe G, van der Putten H, Kafmann S, Caromi P, Ruegg MA.

Exp Gerontol. 2000 Dec;35(9-10):1389-403.

PMID:
11113617
25.

Neuropathology in mice expressing human alpha-synuclein.

van der Putten H, Wiederhold KH, Probst A, Barbieri S, Mistl C, Danner S, Kauffmann S, Hofele K, Spooren WP, Ruegg MA, Lin S, Caroni P, Sommer B, Tolnay M, Bilbe G.

J Neurosci. 2000 Aug 15;20(16):6021-9.

26.

Regulation of epidermal homeostasis through P2Y2 receptors.

Dixon CJ, Bowler WB, Littlewood-Evans A, Dillon JP, Bilbe G, Sharpe GR, Gallagher JA.

Br J Pharmacol. 1999 Aug;127(7):1680-6.

27.

Cloning of a cDNA encoding a novel cytochrome P450 from the insect Locusta migratoria: CYP6H1, a putative ecdysone 20-hydroxylase.

Winter J, Bilbe G, Richener H, Sehringer B, Kayser H.

Biochem Biophys Res Commun. 1999 Jun 7;259(2):305-10.

PMID:
10362503
29.

P2Y receptor subtypes differentially couple to inwardly-rectifying potassium channels.

Mosbacher J, Maier R, Fakler B, Glatz A, Crespo J, Bilbe G.

FEBS Lett. 1998 Sep 25;436(1):104-10.

30.

Parathyroid hormone responses of cyclic AMP-, serum- and phorbol ester-responsive reporter genes in osteoblast-like UMR-106 cells.

Flühmann B, Zimmermann U, Muff R, Bilbe G, Fischer JA, Born W.

Mol Cell Endocrinol. 1998 Apr 30;139(1-2):89-98.

PMID:
9705077
31.

MAP kinase signaling cascades and gene expression in osteoblasts.

Hipskind RA, Bilbe G.

Front Biosci. 1998 Aug 1;3:d804-16. Review.

PMID:
9682034
32.

G-protein coupled receptors in bone.

Bowler WB, Gallagher JA, Bilbe G.

Front Biosci. 1998 Aug 1;3:d769-80. Review.

PMID:
9682032
33.
34.

P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption.

Bowler WB, Littlewood-Evans A, Bilbe G, Gallagher JA, Dixon CJ.

Bone. 1998 Mar;22(3):195-200.

PMID:
9514211
35.

The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma.

Littlewood-Evans AJ, Bilbe G, Bowler WB, Farley D, Wlodarski B, Kokubo T, Inaoka T, Sloane J, Evans DB, Gallagher JA.

Cancer Res. 1997 Dec 1;57(23):5386-90.

36.

Cloning of P2Y6 cDNAs and identification of a pseudogene: comparison of P2Y receptor subtype expression in bone and brain tissues.

Maier R, Glatz A, Mosbacher J, Bilbe G.

Biochem Biophys Res Commun. 1997 Nov 17;240(2):298-302.

PMID:
9412455
37.

Effects of PTH on PTHrP gene expression in human osteoblasts: up-regulation with the kinetics of an immediate early gene.

Walsh CA, Bowler WB, Bilbe G, Fraser WD, Gallagher JA.

Biochem Biophys Res Commun. 1997 Oct 9;239(1):155-9.

PMID:
9345287
38.

Cloning of P2Y6 cDNAs and identification of a pseudogene: comparison of P2Y receptor subtype expression in bone and brain tissues.

Maier R, Glatz A, Mosbacher J, Bilbe G.

Biochem Biophys Res Commun. 1997 Aug 18;237(2):297-302. Corrected and republished in: Biochem Biophys Res Commun. 1997 Nov 17;240(2):298-302.

PMID:
9268704
39.

Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry.

Littlewood-Evans A, Kokubo T, Ishibashi O, Inaoka T, Wlodarski B, Gallagher JA, Bilbe G.

Bone. 1997 Feb;20(2):81-6.

PMID:
9028530
40.

Maintenance of intestinal epithelium structural integrity and mucosal leukocytes during chemotherapy by oral administration of muramyl tripeptide phosphatidylethanolamine.

Killion JJ, Bucana CD, Radinsky R, Dong Z, O'Reilly T, Bilbe G, Tarcsay L, Fidler IJ.

Cancer Biother Radiopharm. 1996 Dec;11(6):363-71.

PMID:
10851497
41.
42.
43.

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.

Arning S, Grüter P, Bilbe G, Krämer A.

RNA. 1996 Aug;2(8):794-810.

44.

The ubiquitous VA68 isoform of subunit A of the vacuolar H(+)-ATPase is highly expressed in human osteoclasts.

van Hille B, Richener H, Green JR, Bilbe G.

Biochem Biophys Res Commun. 1995 Sep 25;214(3):1108-13.

PMID:
7575517
45.
46.

Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts.

Bowler WB, Birch MA, Gallagher JA, Bilbe G.

J Bone Miner Res. 1995 Jul;10(7):1137-45.

PMID:
7484291
48.

Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase.

Andjelković M, Jones PF, Grossniklaus U, Cron P, Schier AF, Dick M, Bilbe G, Hemmings BA.

J Biol Chem. 1995 Feb 24;270(8):4066-75.

49.

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone.

Inaoka T, Bilbe G, Ishibashi O, Tezuka K, Kumegawa M, Kokubo T.

Biochem Biophys Res Commun. 1995 Jan 5;206(1):89-96.

PMID:
7818555
50.

Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.

Krämer A, Legrain P, Mulhauser F, Gröning K, Brosi R, Bilbe G.

Nucleic Acids Res. 1994 Dec 11;22(24):5223-8.

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