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Items: 39


The Androgen Receptor in Breast Cancer.

Giovannelli P, Di Donato M, Galasso G, Di Zazzo E, Bilancio A, Migliaccio A.

Front Endocrinol (Lausanne). 2018 Aug 28;9:492. doi: 10.3389/fendo.2018.00492. eCollection 2018. Review.


Bisphenol A induces cell cycle arrest in primary and prostate cancer cells through EGFR/ERK/p53 signaling pathway activation.

Bilancio A, Bontempo P, Di Donato M, Conte M, Giovannelli P, Altucci L, Migliaccio A, Castoria G.

Oncotarget. 2017 Dec 18;8(70):115620-115631. doi: 10.18632/oncotarget.23360. eCollection 2017 Dec 29.


Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury.

Bilancio A, Rinaldi B, Oliviero MA, Donniacuo M, Monti MG, Boscaino A, Marino I, Friedman L, Rossi F, Vanhaesebroeck B, Migliaccio A.

Biosci Rep. 2017 Sep 27;37(5). pii: BSR20171112. doi: 10.1042/BSR20171112. Print 2017 Oct 31.


Recent advances on bisphenol-A and endocrine disruptor effects on human prostate cancer.

Di Donato M, Cernera G, Giovannelli P, Galasso G, Bilancio A, Migliaccio A, Castoria G.

Mol Cell Endocrinol. 2017 Dec 5;457:35-42. doi: 10.1016/j.mce.2017.02.045. Epub 2017 Feb 28. Review.


Cross-talk between androgen receptor/filamin A and TrkA regulates neurite outgrowth in PC12 cells.

Di Donato M, Bilancio A, D'Amato L, Claudiani P, Oliviero MA, Barone MV, Auricchio A, Appella E, Migliaccio A, Auricchio F, Castoria G.

Mol Biol Cell. 2015 Aug 1;26(15):2858-72. doi: 10.1091/mbc.E14-09-1352. Epub 2015 Jun 10.


Non-genomic androgen action regulates proliferative/migratory signaling in stromal cells.

Di Donato M, Giovannelli P, Cernera G, Di Santi A, Marino I, Bilancio A, Galasso G, Auricchio F, Migliaccio A, Castoria G.

Front Endocrinol (Lausanne). 2015 Jan 19;5:225. doi: 10.3389/fendo.2014.00225. eCollection 2014. Review.


Phosphoinositide 3-kinase assay in breast cancer cell extracts.

Bilancio A, Migliaccio A.

Methods Mol Biol. 2014;1204:145-53. doi: 10.1007/978-1-4939-1346-6_13.


Polyproline and Tat transduction peptides in the study of the rapid actions of steroid receptors.

Migliaccio A, Castoria G, de Falco A, Bilancio A, Giovannelli P, Di Donato M, Marino I, Yamaguchi H, Appella E, Auricchio F.

Steroids. 2012 Aug;77(10):974-8. doi: 10.1016/j.steroids.2012.01.014. Epub 2012 Jan 28. Review.


Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.

Papakonstanti EA, Zwaenepoel O, Bilancio A, Burns E, Nock GE, Houseman B, Shokat K, Ridley AJ, Vanhaesebroeck B.

J Cell Sci. 2008 Dec 15;121(Pt 24):4124-33. doi: 10.1242/jcs.032763. Epub 2008 Nov 25.


The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, Meek S, Smith AJ, Okkenhaug K, Vanhaesebroeck B.

Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8292-7. doi: 10.1073/pnas.0707761105. Epub 2008 Jun 10.


Integrating signals between cAMP and MAPK pathways in breast cancer.

Castoria G, Migliaccio A, D'Amato L, Di Stasio R, Ciociola A, Lombardi M, Bilancio A, Di Domenico M, de Falco A, Auricchio F.

Front Biosci. 2008 Jan 1;13:1318-27. Review.


Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B.

PLoS One. 2007 Sep 11;2(9):e869.


Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.

Ji H, Rintelen F, Waltzinger C, Bertschy Meier D, Bilancio A, Pearce W, Hirsch E, Wymann MP, Rückle T, Camps M, Vanhaesebroeck B, Okkenhaug K, Rommel C.

Blood. 2007 Oct 15;110(8):2940-7. Epub 2007 Jul 12.


The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells.

Okkenhaug K, Patton DT, Bilancio A, Garçon F, Rowan WC, Vanhaesebroeck B.

J Immunol. 2006 Oct 15;177(8):5122-8.


Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells.

Spender LC, Lucchesi W, Bodelon G, Bilancio A, Karstegl CE, Asano T, Dittrich-Breiholz O, Kracht M, Vanhaesebroeck B, Farrell PJ.

J Gen Virol. 2006 Oct;87(Pt 10):2859-67.


Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action.

Migliaccio A, Di Domenico M, Castoria G, Nanayakkara M, Lombardi M, de Falco A, Bilancio A, Varricchio L, Ciociola A, Auricchio F.

Cancer Res. 2005 Nov 15;65(22):10585-93.


Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells.

Bilancio A, Okkenhaug K, Camps M, Emery JL, Ruckle T, Rommel C, Vanhaesebroeck B.

Blood. 2006 Jan 15;107(2):642-50. Epub 2005 Sep 22.


Signalling by PI3K isoforms: insights from gene-targeted mice.

Vanhaesebroeck B, Ali K, Bilancio A, Geering B, Foukas LC.

Trends Biochem Sci. 2005 Apr;30(4):194-204. Review.


Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition.

Abell K, Bilancio A, Clarkson RW, Tiffen PG, Altaparmakov AI, Burdon TG, Asano T, Vanhaesebroeck B, Watson CJ.

Nat Cell Biol. 2005 Apr;7(4):392-8. Epub 2005 Mar 27.


Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.

Ali K, Bilancio A, Thomas M, Pearce W, Gilfillan AM, Tkaczyk C, Kuehn N, Gray A, Giddings J, Peskett E, Fox R, Bruce I, Walker C, Sawyer C, Okkenhaug K, Finan P, Vanhaesebroeck B.

Nature. 2004 Oct 21;431(7011):1007-11.


Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells.

Castoria G, Migliaccio A, Di Domenico M, Lombardi M, de Falco A, Varricchio L, Bilancio A, Barone MV, Auricchio F.

Mol Cell Biol. 2004 Sep;24(17):7643-53.


Rapid signalling pathway activation by androgens in epithelial and stromal cells.

Castoria G, Lombardi M, Barone MV, Bilancio A, Di Domenico M, De Falco A, Varricchio L, Bottero D, Nanayakkara M, Migliaccio A, Auricchio F.

Steroids. 2004 Aug;69(8-9):517-22. Review.


Phosphoinositide 3-kinase in T cell activation and survival.

Okkenhaug K, Bilancio A, Emery JL, Vanhaesebroeck B.

Biochem Soc Trans. 2004 Apr;32(Pt 2):332-5. Review.


Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages.

Leverrier Y, Okkenhaug K, Sawyer C, Bilancio A, Vanhaesebroeck B, Ridley AJ.

J Biol Chem. 2003 Oct 3;278(40):38437-42. Epub 2003 Jul 16.


Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action.

Castoria G, Lombardi M, Barone MV, Bilancio A, Di Domenico M, Bottero D, Vitale F, Migliaccio A, Auricchio F.

J Cell Biol. 2003 May 12;161(3):547-56.


Sex steroid hormones act as growth factors.

Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Bottero D, Varricchio L, Nanayakkara M, Rotondi A, Auricchio F.

J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):31-5. Review.


Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats.

Indolfi C, Torella D, Coppola C, Curcio A, Rodriguez F, Bilancio A, Leccia A, Arcucci O, Falco M, Leosco D, Chiariello M.

Circ Res. 2002 Dec 13;91(12):1190-7.


Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.

Okkenhaug K, Bilancio A, Farjot G, Priddle H, Sancho S, Peskett E, Pearce W, Meek SE, Salpekar A, Waterfield MD, Smith AJ, Vanhaesebroeck B.

Science. 2002 Aug 9;297(5583):1031-4. Epub 2002 Jul 18.


Src is an initial target of sex steroid hormone action.

Migliaccio A, Castoria G, Di Domenico M, De Falco A, Bilancio A, Auricchio F.

Ann N Y Acad Sci. 2002 Jun;963:185-90.


PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells.

Castoria G, Migliaccio A, Bilancio A, Di Domenico M, de Falco A, Lombardi M, Fiorentino R, Varricchio L, Barone MV, Auricchio F.

EMBO J. 2001 Nov 1;20(21):6050-9.


Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation.

Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Barone MV, Ametrano D, Zannini MS, Abbondanza C, Auricchio F.

EMBO J. 2000 Oct 16;19(20):5406-17.


Urinary neopterin and kynurenine in patients submitted to surgical stress with different inhalational anesthetics (halothane or isoflurane).

Marfella A, Bilancio A, Polese C, Iodice F, Edmondo C, Cerasuolo D, Esposito G, Zannoni V, Beneduce G.

Int J Immunopharmacol. 1999 Jul;21(7):423-33.


Non-transcriptional action of oestradiol and progestin triggers DNA synthesis.

Castoria G, Barone MV, Di Domenico M, Bilancio A, Ametrano D, Migliaccio A, Auricchio F.

EMBO J. 1999 May 4;18(9):2500-10.


Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor.

Migliaccio A, Piccolo D, Castoria G, Di Domenico M, Bilancio A, Lombardi M, Gong W, Beato M, Auricchio F.

EMBO J. 1998 Apr 1;17(7):2008-18.


Estradiol activation of human colon carcinoma-derived Caco-2 cell growth.

Di Domenico M, Castoria G, Bilancio A, Migliaccio A, Auricchio F.

Cancer Res. 1996 Oct 1;56(19):4516-21.


Protein tyrosine phosphorylation and estradiol action.

Auricchio F, Migliaccio A, Castoria G, Di Domenico M, Bilancio A, Rotondi A.

Ann N Y Acad Sci. 1996 Apr 30;784:149-72. Review. No abstract available.


A 67 kDa non-hormone binding estradiol receptor is present in human mammary cancers.

Castoria G, Migliaccio A, Bilancio A, Pagano M, Abbondanza C, Auricchio F.

Int J Cancer. 1996 Mar 1;65(5):574-83.


The role of estradiol receptor in the proliferative activity of vanadate on MCF-7 cells.

Auricchio F, Di Domenico M, Migliaccio A, Castoria G, Bilancio A.

Cell Growth Differ. 1995 Feb;6(2):105-13.


Epidermal growth factor induces protein tyrosine phosphorylation and association of p190 with ras-GTP-ase activating protein in Caco-2 cells.

Auricchio A, di Domenico M, Castoria G, Bilancio A, Migliaccio A.

FEBS Lett. 1994 Oct 10;353(1):16-20.

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