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Items: 46


Risk-Based Bioengineering Strategies for Reliable Bacterial Vaccine Production.

Kamminga T, Slagman SJ, Martins Dos Santos VAP, Bijlsma JJE, Schaap PJ.

Trends Biotechnol. 2019 Aug;37(8):805-816. doi: 10.1016/j.tibtech.2019.03.005. Epub 2019 Apr 5. Review.


The antibody response in the bovine mammary gland is influenced by the adjuvant and the site of subcutaneous vaccination.

Boerhout EM, Koets AP, Mols-Vorstermans TGT, Nuijten PJM, Hoeijmakers MJH, Rutten VPMG, Bijlsma JJE.

Vet Res. 2018 Mar 1;49(1):25. doi: 10.1186/s13567-018-0521-2.


Metabolic modeling of energy balances in Mycoplasma hyopneumoniae shows that pyruvate addition increases growth rate.

Kamminga T, Slagman SJ, Bijlsma JJE, Martins Dos Santos VAP, Suarez-Diez M, Schaap PJ.

Biotechnol Bioeng. 2017 Oct;114(10):2339-2347. doi: 10.1002/bit.26347. Epub 2017 Jul 27.


Persistence of Functional Protein Domains in Mycoplasma Species and their Role in Host Specificity and Synthetic Minimal Life.

Kamminga T, Koehorst JJ, Vermeij P, Slagman SJ, Martins Dos Santos VA, Bijlsma JJ, Schaap PJ.

Front Cell Infect Microbiol. 2017 Feb 7;7:31. doi: 10.3389/fcimb.2017.00031. eCollection 2017.


Reisolation of Staphylococcus aureus from bovine milk following experimental inoculation is influenced by fat percentage and specific immunoglobulin G1 titer in milk.

Boerhout EM, Koets AP, Vernooij JCM, Mols-Vorstermans TGT, Nuijten PJM, Rutten VPMG, Bijlsma JJE, Eisenberg SWF.

J Dairy Sci. 2016 Jun;99(6):4259-4269. doi: 10.3168/jds.2015-10648. Epub 2016 Mar 16.


Feasibility of a Website and a Hospital-Based Online Portal for Young Adults With Juvenile Idiopathic Arthritis: Views and Experiences of Patients.

Ammerlaan JJ, Scholtus LW, Drossaert CH, van Os-Medendorp H, Prakken B, Kruize AA, Bijlsma JJ.

JMIR Res Protoc. 2015 Aug 14;4(3):e102. doi: 10.2196/resprot.3952.


Streptococcus pneumoniae Interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor.

Iovino F, Molema G, Bijlsma JJ.

PLoS One. 2014 May 19;9(5):e97914. doi: 10.1371/journal.pone.0097914. eCollection 2014.


Influence of impaired lipoprotein biogenesis on surface and exoproteome of Streptococcus pneumoniae.

Pribyl T, Moche M, Dreisbach A, Bijlsma JJ, Saleh M, Abdullah MR, Hecker M, van Dijl JM, Becher D, Hammerschmidt S.

J Proteome Res. 2014 Feb 7;13(2):650-67. doi: 10.1021/pr400768v. Epub 2014 Jan 15.


Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis.

Iovino F, Orihuela CJ, Moorlag HE, Molema G, Bijlsma JJ.

PLoS One. 2013 Jul 16;8(7):e68408. doi: 10.1371/journal.pone.0068408. Print 2013.


Pyruvate oxidase influences the sugar utilization pattern and capsule production in Streptococcus pneumoniae.

Carvalho SM, Farshchi Andisi V, Gradstedt H, Neef J, Kuipers OP, Neves AR, Bijlsma JJ.

PLoS One. 2013 Jul 3;8(7):e68277. doi: 10.1371/journal.pone.0068277. Print 2013.


Streptococcus pneumoniae invades endothelial host cells via multiple pathways and is killed in a lysosome dependent manner.

Gradstedt H, Iovino F, Bijlsma JJ.

PLoS One. 2013 Jun 13;8(6):e65626. doi: 10.1371/journal.pone.0065626. Print 2013.


Signalling or binding: the role of the platelet-activating factor receptor in invasive pneumococcal disease.

Iovino F, Brouwer MC, van de Beek D, Molema G, Bijlsma JJ.

Cell Microbiol. 2013 Jun;15(6):870-81. doi: 10.1111/cmi.12129. Epub 2013 Mar 20. Review.


Streptococcus pneumoniae and reactive oxygen species: an unusual approach to living with radicals.

Yesilkaya H, Andisi VF, Andrew PW, Bijlsma JJ.

Trends Microbiol. 2013 Apr;21(4):187-95. doi: 10.1016/j.tim.2013.01.004. Epub 2013 Feb 13. Review.


Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance.

Gant CM, Rosingh AW, López-Hontangas JL, van der Heijden M, González-Morán F, Bijlsma JJ, Canton E; RedMiva (Network of Microbiological Vigilance of Comunidad Valenciana).

Antimicrob Agents Chemother. 2012 Sep;56(9):4988-9. doi: 10.1128/AAC.01201-12. Epub 2012 Jul 2. No abstract available.


Pneumococcal gene complex involved in resistance to extracellular oxidative stress.

Andisi VF, Hinojosa CA, de Jong A, Kuipers OP, Orihuela CJ, Bijlsma JJ.

Infect Immun. 2012 Mar;80(3):1037-49. doi: 10.1128/IAI.05563-11. Epub 2012 Jan 3.


Deletion of a cation transporter promotes lysis in Streptococcus pneumoniae.

Neef J, Andisi VF, Kim KS, Kuipers OP, Bijlsma JJ.

Infect Immun. 2011 Jun;79(6):2314-23. doi: 10.1128/IAI.00677-10. Epub 2011 Mar 21.


Carbonic anhydrase is essential for Streptococcus pneumoniae growth in environmental ambient air.

Burghout P, Cron LE, Gradstedt H, Quintero B, Simonetti E, Bijlsma JJ, Bootsma HJ, Hermans PW.

J Bacteriol. 2010 Aug;192(15):4054-62. doi: 10.1128/JB.00151-10. Epub 2010 Jun 4.


Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence.

Majchrzykiewicz JA, Lubelski J, Moll GN, Kuipers A, Bijlsma JJ, Kuipers OP, Rink R.

Antimicrob Agents Chemother. 2010 Apr;54(4):1498-505. doi: 10.1128/AAC.00883-09. Epub 2010 Jan 25.


Generic and specific adaptive responses of Streptococcus pneumoniae to challenge with three distinct antimicrobial peptides, bacitracin, LL-37, and nisin.

Majchrzykiewicz JA, Kuipers OP, Bijlsma JJ.

Antimicrob Agents Chemother. 2010 Jan;54(1):440-51. doi: 10.1128/AAC.00769-09. Epub 2009 Nov 16.


Intranasal administration of recombinant human cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: a phase II, multicentre, double-blind, randomised, placebo-controlled, parallel-group, dose-finding trial.

Landewé RB, Houbiers JG, Van den Bosch F, in't Hout J, Verschueren PC, Meijerink JH, van den Hoogen FH, Masek BA, Bruyn GA, Wouters JM, Voskuyl AE, van Laar JM, Bijlsma JJ, van der Heijde DM, Breedveld FC, van de Putte LB, Miltenburg AM, de Keyser F.

Ann Rheum Dis. 2010 Sep;69(9):1655-9. doi: 10.1136/ard.2009.117234. Epub 2009 Sep 23.


Adherence to emergency department discharge prescriptions.

Hohl CM, Abu-Laban RB, Brubacher JR, Zed PJ, Sobolev B, Tsai G, Kretz P, Nemethy K, Bijlsma JJ, Purssell RA.

CJEM. 2009 Mar;11(2):131-8.


Opposite effects of Mn2+ and Zn2+ on PsaR-mediated expression of the virulence genes pcpA, prtA, and psaBCA of Streptococcus pneumoniae.

Kloosterman TG, Witwicki RM, van der Kooi-Pol MM, Bijlsma JJ, Kuipers OP.

J Bacteriol. 2008 Aug;190(15):5382-93. doi: 10.1128/JB.00307-08. Epub 2008 May 30.


The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae.

Kloosterman TG, van der Kooi-Pol MM, Bijlsma JJ, Kuipers OP.

Mol Microbiol. 2007 Aug;65(4):1049-63. Epub 2007 Jul 19.


Search for genes essential for pneumococcal transformation: the RADA DNA repair protein plays a role in genomic recombination of donor DNA.

Burghout P, Bootsma HJ, Kloosterman TG, Bijlsma JJ, de Jongh CE, Kuipers OP, Hermans PW.

J Bacteriol. 2007 Sep;189(18):6540-50. Epub 2007 Jul 13.


Development of genomic array footprinting for identification of conditionally essential genes in Streptococcus pneumoniae.

Bijlsma JJ, Burghout P, Kloosterman TG, Bootsma HJ, de Jong A, Hermans PW, Kuipers OP.

Appl Environ Microbiol. 2007 Mar;73(5):1514-24. Epub 2007 Jan 19.


BAGEL: a web-based bacteriocin genome mining tool.

de Jong A, van Hijum SA, Bijlsma JJ, Kok J, Kuipers OP.

Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W273-9.


Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae.

Kloosterman TG, Hendriksen WT, Bijlsma JJ, Bootsma HJ, van Hijum SA, Kok J, Hermans PW, Kuipers OP.

J Biol Chem. 2006 Sep 1;281(35):25097-109. Epub 2006 Jun 20.


To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae.

Kloosterman TG, Bijlsma JJ, Kok J, Kuipers OP.

Microbiology. 2006 Feb;152(Pt 2):351-9.


Making informed decisions: regulatory interactions between two-component systems.

Bijlsma JJ, Groisman EA.

Trends Microbiol. 2003 Aug;11(8):359-66. Review. No abstract available.


The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake.

van Vliet AH, Stoof J, Vlasblom R, Wainwright SA, Hughes NJ, Kelly DJ, Bereswill S, Bijlsma JJ, Hoogenboezem T, Vandenbroucke-Grauls CM, Kist M, Kuipers EJ, Kusters JG.

Helicobacter. 2002 Aug;7(4):237-44.


Identification of environmental stress-regulated genes in Helicobacter pylori by a lacZ reporter gene fusion system.

de Vries N, Kuipers EJ, Kramer NE, van Vliet AH, Bijlsma JJ, Kist M, Bereswill S, Vandenbroucke-Grauls CM, Kusters JG.

Helicobacter. 2001 Dec;6(4):300-9.


The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance.

Bijlsma JJ, Waidner B, Vliet AH, Hughes NJ, Häg S, Bereswill S, Kelly DJ, Vandenbroucke-Grauls CM, Kist M, Kusters JG.

Infect Immun. 2002 Feb;70(2):606-11.


Phase variation in the Helicobacter pylori phospholipase A gene and its role in acid adaptation.

Tannaes T, Dekker N, Bukholm G, Bijlsma JJ, Appelmelk BJ.

Infect Immun. 2001 Dec;69(12):7334-40.


The Bacillus subtilis competence transcription factor, ComK, overrides LexA-imposed transcriptional inhibition without physically displacing LexA.

Hamoen LW, Haijema B, Bijlsma JJ, Venema G, Lovett CM.

J Biol Chem. 2001 Nov 16;276(46):42901-7. Epub 2001 Sep 12.


Identification of loci essential for the growth of Helicobacter pylori under acidic conditions.

Bijlsma JJ, Lie-A-Ling M, Nootenboom IC, Vandenbroucke-Grauls CM, Kusters JG.

J Infect Dis. 2000 Nov;182(5):1566-9. Epub 2000 Oct 9.


comH, a novel gene essential for natural transformation of Helicobacter pylori.

Smeets LC, Bijlsma JJ, Boomkens SY, Vandenbroucke-Grauls CM, Kusters JG.

J Bacteriol. 2000 Jul;182(14):3948-54.


The dprA gene is required for natural transformation of Helicobacter pylori.

Smeets LC, Bijlsma JJ, Kuipers EJ, Vandenbroucke-Grauls CM, Kusters JG.

FEMS Immunol Med Microbiol. 2000 Feb;27(2):99-102.


Identification of virulence genes of Helicobacter pylori by random insertion mutagenesis.

Bijlsma JJ, Vandenbroucke-Grauls CM, Phadnis SH, Kusters JG.

Infect Immun. 1999 May;67(5):2433-40.


Cloning of fibA, encoding an immunogenic subunit of the fibril-like surface structure of Peptostreptococcus micros.

Kremer BH, Bijlsma JJ, Kusters JG, de Graaff J, van Steenbergen TJ.

J Bacteriol. 1999 Apr;181(8):2485-91.


Urease-positive, acid-sensitive mutants of Helicobacter pylori: urease-independent acid resistance involved in growth at low pH.

Bijlsma JJ, Gerrits MM, Imamdi R, Vandenbroucke-Grauls CM, Kusters JG.

FEMS Microbiol Lett. 1998 Oct 15;167(2):309-13.


Sustained release and standard methylphenidate effects on cognitive and social behavior in children with attention deficit disorder.

Pelham WE Jr, Sturges J, Hoza J, Schmidt C, Bijlsma JJ, Milich R, Moorer S.

Pediatrics. 1987 Oct;80(4):491-501.


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