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Items: 1 to 50 of 79

1.

Maximal Dexamethasone Inhibition of Luminal Epithelial Proliferation Involves Progesterone Receptor (PR)- and Non-PR-Mediated Mechanisms in Neonatal Mouse Uterus.

Nanjappa MK, Medrano TI, Lydon JP, Bigsby RM, Cooke PS.

Biol Reprod. 2015 May;92(5):122. doi: 10.1095/biolreprod.114.123463. Epub 2015 Apr 16.

PMID:
25882702
2.

Subcutaneous wounding postirradiation reduces radiation lethality in mice.

Garrett J, Orschell CM, Mendonca MS, Bigsby RM, Dynlacht JR.

Radiat Res. 2014 Jun;181(6):578-83. doi: 10.1667/RR13267.1. Epub 2014 May 8.

PMID:
24811864
3.

Error-promoting DNA synthesis in ovarian cancer cells.

Dai H, Hickey RJ, Liu J, Bigsby RM, Lanner C, Malkas LH.

Gynecol Oncol. 2013 Oct;131(1):198-206. doi: 10.1016/j.ygyno.2013.06.022. Epub 2013 Jul 12.

4.

Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. II. Sparsely ionizing (low-LET) radiation.

Dynlacht JR, Valluri S, Garrett J, Nees J, Caperell-Grant A, DesRosiers C, Bigsby RM.

Radiat Res. 2012 Oct;178(4):260-5. Epub 2012 Aug 10.

PMID:
22880623
5.

The role for estrogen receptor-alpha and prolactin receptor in sex-dependent DEN-induced liver tumorigenesis.

Bigsby RM, Caperell-Grant A.

Carcinogenesis. 2011 Aug;32(8):1162-6. doi: 10.1093/carcin/bgr094. Epub 2011 May 23.

6.

Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. I. Densely ionizing (high-LET) radiation.

Dynlacht JR, Valluri S, Garrett J, Mendonca MS, Lopez JT, Caperell-Grant A, Bigsby RM.

Radiat Res. 2011 Jan;175(1):37-43. doi: 10.1667/RR2319.1. Epub 2010 Nov 10.

PMID:
21175345
7.

Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells.

Bapat SA, Jin V, Berry N, Balch C, Sharma N, Kurrey N, Zhang S, Fang F, Lan X, Li M, Kennedy B, Bigsby RM, Huang TH, Nephew KP.

Epigenetics. 2010 Nov-Dec;5(8):716-29. Epub 2010 Nov 1.

8.

Effects of estrogen and gender on cataractogenesis induced by high-LET radiation.

Henderson MA, Valluri S, Garrett J, Lopez JT, Caperell-Grant A, Mendonca MS, Rusek A, Bigsby RM, Dynlacht JR.

Radiat Res. 2010 Feb;173(2):191-6. doi: 10.1667/RR1917.1.

PMID:
20095851
9.

Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase.

Shao M, Cao L, Shen C, Satpathy M, Chelladurai B, Bigsby RM, Nakshatri H, Matei D.

Cancer Res. 2009 Dec 15;69(24):9192-201. doi: 10.1158/0008-5472.CAN-09-1257.

10.

Interstrain differences in the development of pyometra after estrogen treatment of rats.

Brossia LJ, Roberts CS, Lopez JT, Bigsby RM, Dynlacht JR.

J Am Assoc Lab Anim Sci. 2009 Sep;48(5):517-20.

11.

Effect of gender on radiation-induced cataractogenesis.

Henderson MA, Valluri S, DesRosiers C, Lopez JT, Batuello CN, Caperell-Grant A, Mendonca MS, Powers EM, Bigsby RM, Dynlacht JR.

Radiat Res. 2009 Jul;172(1):129-33. doi: 10.1667/RR1589.1.

PMID:
19580515
12.

Ovarian hormone modulation of radiation-induced cataractogenesis: dose-response studies.

Bigsby RM, Valluri S, Lopez J, Mendonca MS, Caperell-Grant A, DesRosiers C, Dynlacht JR.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3304-10. doi: 10.1167/iovs.08-3262. Epub 2009 Feb 28.

PMID:
19255148
13.

Hydroxylated metabolites of polybrominated diphenyl ethers in human blood samples from the United States.

Qiu X, Bigsby RM, Hites RA.

Environ Health Perspect. 2009 Jan;117(1):93-8. doi: 10.1289/ehp.11660. Epub 2008 Aug 1.

14.

Estrogen protects against radiation-induced cataractogenesis.

Dynlacht JR, Valluri S, Lopez J, Greer F, Desrosiers C, Caperell-Grant A, Mendonca MS, Bigsby RM.

Radiat Res. 2008 Dec;170(6):758-64. doi: 10.1667/RR1416.1.

15.

Hydroxylated metabolites of the polybrominated diphenyl ether mixture DE-71 are weak estrogen receptor-alpha ligands.

Mercado-Feliciano M, Bigsby RM.

Environ Health Perspect. 2008 Oct;116(10):1315-21. doi: 10.1289/ehp.11343. Epub 2008 May 27.

16.

Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms.

Long X, Fan M, Bigsby RM, Nephew KP.

Mol Cancer Ther. 2008 Jul;7(7):2096-108. doi: 10.1158/1535-7163.MCT-07-2350.

17.

S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells.

Wang D, Zhao Z, Caperell-Grant A, Yang G, Mok SC, Liu J, Bigsby RM, Xu Y.

Mol Cancer Ther. 2008 Jul;7(7):1993-2002. doi: 10.1158/1535-7163.MCT-08-0088.

18.

Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.

Hammoud Z, Tan B, Badve S, Bigsby RM.

Endocr Relat Cancer. 2008 Jun;15(2):475-83. doi: 10.1677/ERC-08-0002.

PMID:
18509000
19.

The polybrominated diphenyl ether mixture DE-71 is mildly estrogenic.

Mercado-Feliciano M, Bigsby RM.

Environ Health Perspect. 2008 May;116(5):605-11. doi: 10.1289/ehp.10643.

20.

Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase.

Tan B, Long X, Nakshatri H, Nephew KP, Bigsby RM.

J Mol Endocrinol. 2008 May;40(5):199-210. doi: 10.1677/JME-07-0132.

PMID:
18434427
21.
22.

A role for sulfation-desulfation in the uptake of bisphenol a into breast tumor cells.

Stowell CL, Barvian KK, Young PC, Bigsby RM, Verdugo DE, Bertozzi CR, Widlanski TS.

Chem Biol. 2006 Aug;13(8):891-7.

23.

Effect of estrogen on radiation-induced cataractogenesis.

Dynlacht JR, Tyree C, Valluri S, DesRosiers C, Caperell-Grant A, Mendonca MS, Timmerman R, Bigsby RM.

Radiat Res. 2006 Jan;165(1):9-15.

PMID:
16392957
24.

Interleukin-1 alpha promotes tumor growth and cachexia in MCF-7 xenograft model of breast cancer.

Kumar S, Kishimoto H, Chua HL, Badve S, Miller KD, Bigsby RM, Nakshatri H.

Am J Pathol. 2003 Dec;163(6):2531-41.

25.

Use of the Leksell Gamma Knife for localized small field lens irradiation in rodents.

DesRosiers C, Mendonca MS, Tyree C, Moskvin V, Bank M, Massaro L, Bigsby RM, Caperall-Grant A, Valluri S, Dynlacht JR, Timmerman R.

Technol Cancer Res Treat. 2003 Oct;2(5):449-54.

PMID:
14529310
26.

Estrogen induces a systemic growth factor through an estrogen receptor-alpha-dependent mechanism.

Bigsby RM, Caperell-Grant A, Berry N, Nephew K, Lubahn D.

Biol Reprod. 2004 Jan;70(1):178-83. Epub 2003 Sep 17.

PMID:
13679309
27.

Polybrominated diphenyl ethers in maternal and fetal blood samples.

Mazdai A, Dodder NG, Abernathy MP, Hites RA, Bigsby RM.

Environ Health Perspect. 2003 Jul;111(9):1249-52.

29.

Control of growth and differentiation of the endometrium: the role of tissue interactions.

Bigsby RM.

Ann N Y Acad Sci. 2002 Mar;955:110-7; discussion 118, 396-406. Review.

PMID:
11949941
30.
31.

The activating enzyme of NEDD8 inhibits steroid receptor function.

Fan M, Long X, Bailey JA, Reed CA, Osborne E, Gize EA, Kirk EA, Bigsby RM, Nephew KP.

Mol Endocrinol. 2002 Feb;16(2):315-30.

PMID:
11818503
32.

Evidence for estrogenic contamination of the MAPK inhibitor PD98059.

Long X, Gize EA, Nephew K, Bigsby RM.

Endocrinology. 2001 Dec;142(12):5390-3.

PMID:
11713241
33.

Expression and subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in epithelial ovarian cancer.

Hurteau JA, Allison BM, Brutkiewicz SA, Goebl MG, Heilman DK, Bigsby RM, Harrington MA.

Gynecol Oncol. 2001 Nov;83(2):292-8.

PMID:
11606087
34.
35.

DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization.

Ahluwalia A, Yan P, Hurteau JA, Bigsby RM, Jung SH, Huang TH, Nephew KP.

Gynecol Oncol. 2001 Aug;82(2):261-8.

PMID:
11531277
36.

Estrogen receptor beta in the sheep ovary during the estrous cycle and early pregnancy.

Cárdenas H, Burke KA, Bigsby RM, Pope WF, Nephew KP.

Biol Reprod. 2001 Jul;65(1):128-34.

PMID:
11420232
37.

Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat.

Long X, Burke KA, Bigsby RM, Nephew KP.

Exp Biol Med (Maywood). 2001 May;226(5):477-83.

PMID:
11393178
38.

Understanding enantioselective processes: a laboratory rat model for alpha-hexachlorocyclohexane accumulation.

Ulrich EM, Willett KL, Caperell-Grant A, Bigsby RM, Hites RA.

Environ Sci Technol. 2001 Apr 15;35(8):1604-9.

PMID:
11329709
39.

Expression of protein kinase C isozymes in nonpregnant and pregnant human myometrium.

Hurd WW, Fomin VP, Natarajan V, Brown HL, Bigsby RM, Singh DM.

Am J Obstet Gynecol. 2000 Dec;183(6):1525-31.

PMID:
11120522
40.

Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice.

Ulrich EM, Caperell-Grant A, Jung SH, Hites RA, Bigsby RM.

Environ Health Perspect. 2000 Oct;108(10):973-7.

41.

Expression of estrogen receptor coactivators in the rat uterus.

Nephew KP, Ray S, Hlaing M, Ahluwalia A, Wu SD, Long X, Hyder SM, Bigsby RM.

Biol Reprod. 2000 Aug;63(2):361-7.

PMID:
10906038
42.

Immunohistochemical detection of estrogen receptor alpha in male rat spinal cord during development.

Burke KA, Schroeder DM, Abel RA, Richardson SC, Bigsby RM, Nephew KP.

J Neurosci Res. 2000 Aug 1;61(3):329-37.

PMID:
10900080
43.

Strain differences in vaginal responses to the xenoestrogen bisphenol A.

Long X, Steinmetz R, Ben-Jonathan N, Caperell-Grant A, Young PC, Nephew KP, Bigsby RM.

Environ Health Perspect. 2000 Mar;108(3):243-7.

44.

Expression of fos and jun proto-oncogenes in benign versus malignant human uterine tissue.

Nephew KP, Choi CM, Polek TC, McBride R, Bigsby RM, Khan SA, Husseinzadeh N.

Gynecol Oncol. 2000 Mar;76(3):388-96.

PMID:
10684716
45.

Effect of estradiol on estrogen receptor expression in rat uterine cell types.

Nephew KP, Long X, Osborne E, Burke KA, Ahluwalia A, Bigsby RM.

Biol Reprod. 2000 Jan;62(1):168-77.

PMID:
10611082
46.

Protective effects of estrogen in a rat model of age-related cataracts.

Bigsby RM, Cardenas H, Caperell-Grant A, Grubbs CJ.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9328-32.

47.

Transforming growth factor-beta differentially inhibits epithelial ovarian carcinoma cells from primary and metastatic isolates without up-regulation of p21WAF1.

Hurteau JA, Allison B, Sutton GP, Moore DH, Look KY, Hurd W, Bigsby RM.

Cancer. 1999 Apr 15;85(8):1810-5.

PMID:
10223576
48.

A 310-bp minimal promoter mediates smooth muscle cell-specific expression of telokin.

Smith AF, Bigsby RM, Word RA, Herring BP.

Am J Physiol. 1998 May;274(5 Pt 1):C1188-95; discussion C1187.

PMID:
9612204
49.

The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract.

Steinmetz R, Mitchner NA, Grant A, Allen DL, Bigsby RM, Ben-Jonathan N.

Endocrinology. 1998 Jun;139(6):2741-7.

PMID:
9607780
50.

Organochlorine residues and breast cancer.

Bigsby RM, Steinmetz R.

N Engl J Med. 1998 Apr 2;338(14):990; author reply 991. No abstract available.

PMID:
9527609

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