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Items: 32

1.

Non-viral ocular gene therapy, pEYS606, for the treatment of non-infectious uveitis: Preclinical evaluation of the medicinal product.

Touchard E, Benard R, Bigot K, Laffitte JD, Buggage R, Bordet T, Behar-Cohen F.

J Control Release. 2018 Sep 10;285:244-251. doi: 10.1016/j.jconrel.2018.07.013. Epub 2018 Aug 1. Review.

PMID:
30009894
2.

Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells.

Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S.

Cell Death Dis. 2018 Feb 19;9(3):287. doi: 10.1038/s41419-018-0331-5.

3.

Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice.

Beckmann N, Doelemeyer A, Zurbruegg S, Bigot K, Theil D, Frieauff W, Kolly C, Moulin P, Neddermann D, Kreutzer R, Perrot L, Brzak I, Jacobson LH, Staufenbiel M, Neumann U, Shimshek DR.

Neurobiol Aging. 2016 Sep;45:50-60. doi: 10.1016/j.neurobiolaging.2016.05.009. Epub 2016 May 17.

4.

Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.

Shimshek DR, Jacobson LH, Kolly C, Zamurovic N, Balavenkatraman KK, Morawiec L, Kreutzer R, Schelle J, Jucker M, Bertschi B, Theil D, Heier A, Bigot K, Beltz K, Machauer R, Brzak I, Perrot L, Neumann U.

Sci Rep. 2016 Feb 25;6:21917. doi: 10.1038/srep21917.

5.

Phototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditions.

Arnault E, Barrau C, Nanteau C, Gondouin P, Bigot K, Viénot F, Gutman E, Fontaine V, Villette T, Cohen-Tannoudji D, Sahel JA, Picaud S.

PLoS One. 2013 Aug 23;8(8):e71398. doi: 10.1371/journal.pone.0071398. eCollection 2013.

6.

AON-mediated Exon Skipping Restores Ciliation in Fibroblasts Harboring the Common Leber Congenital Amaurosis CEP290 Mutation.

Gerard X, Perrault I, Hanein S, Silva E, Bigot K, Defoort-Delhemmes S, Rio M, Munnich A, Scherman D, Kaplan J, Kichler A, Rozet JM.

Mol Ther Nucleic Acids. 2012 Jun 26;1:e29. doi: 10.1038/mtna.2012.21.

7.

Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations.

Perrault I, Saunier S, Hanein S, Filhol E, Bizet AA, Collins F, Salih MA, Gerber S, Delphin N, Bigot K, Orssaud C, Silva E, Baudouin V, Oud MM, Shannon N, Le Merrer M, Roche O, Pietrement C, Goumid J, Baumann C, Bole-Feysot C, Nitschke P, Zahrate M, Beales P, Arts HH, Munnich A, Kaplan J, Antignac C, Cormier-Daire V, Rozet JM.

Am J Hum Genet. 2012 May 4;90(5):864-70. doi: 10.1016/j.ajhg.2012.03.006. Epub 2012 Apr 12.

8.

A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor.

Chabot S, Jabrane-Ferrat N, Bigot K, Tabiasco J, Provost A, Golzio M, Noman MZ, Giustiniani J, Bellard E, Brayer S, Aguerre-Girr M, Meggetto F, Giuriato S, Malecaze F, Galiacy S, Jaïs JP, Chose O, Kadouche J, Chouaib S, Teissié J, Abitbol M, Bensussan A, Le Bouteiller P.

J Exp Med. 2011 May 9;208(5):973-86. doi: 10.1084/jem.20100810. Epub 2011 Apr 11.

9.

Phenotypic variability in a French family with a novel mutation in the BEST1 gene causing multifocal best vitelliform macular dystrophy.

Lacassagne E, Dhuez A, Rigaudière F, Dansault A, Vêtu C, Bigot K, Vieira V, Puech B, Defoort-Dhellemmes S, Abitbol M.

Mol Vis. 2011 Jan 29;17:309-22.

10.

Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina.

Bigot K, Leemput J, Vacher M, Campalans A, Radicella JP, Lacassagne E, Provost A, Masson C, Menasche M, Abitbol M.

Mol Vis. 2009 Jun 5;15:1139-52.

11.

Morphologic and electroretinographic phenotype of SR-BI knockout mice after a long-term atherogenic diet.

Provost AC, Vede L, Bigot K, Keller N, Tailleux A, Jaïs JP, Savoldelli M, Ameqrane I, Lacassagne E, Legeais JM, Staels B, Menasche M, Mallat Z, Behar-Cohen F, Abitbol M.

Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3931-42. doi: 10.1167/iovs.08-2527. Epub 2009 May 6.

PMID:
19420333
12.

Sirt1 involvement in rd10 mouse retinal degeneration.

Jaliffa C, Ameqrane I, Dansault A, Leemput J, Vieira V, Lacassagne E, Provost A, Bigot K, Masson C, Menasche M, Abitbol M.

Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3562-72. doi: 10.1167/iovs.08-2817. Epub 2009 Apr 30.

PMID:
19407027
13.

CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation.

Auffray C, Fogg DK, Narni-Mancinelli E, Senechal B, Trouillet C, Saederup N, Leemput J, Bigot K, Campisi L, Abitbol M, Molina T, Charo I, Hume DA, Cumano A, Lauvau G, Geissmann F.

J Exp Med. 2009 Mar 16;206(3):595-606. doi: 10.1084/jem.20081385. Epub 2009 Mar 9.

14.

ATM localization and gene expression in the adult mouse eye.

Leemput J, Masson C, Bigot K, Errachid A, Dansault A, Provost A, Gadin S, Aoufouchi S, Menasche M, Abitbol M.

Mol Vis. 2009;15:393-416. Epub 2009 Feb 20.

15.

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes.

Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, Brooks BP, Vijayalakshmi P, Sauvé Y, Abitbol M, Sundaresan P, van Heyningen V, Pourquié O, Underhill TM, Waskiewicz AJ, Lehmann OJ.

Hum Mol Genet. 2009 Mar 15;18(6):1110-21. doi: 10.1093/hmg/ddp008. Epub 2009 Jan 6.

PMID:
19129173
16.

Novel mouse model of monocular amaurosis fugax.

Lelong DC, Bieche I, Perez E, Bigot K, Leemput J, Laurendeau I, Vidaud M, Jais JP, Menasche M, Abitbol M.

Stroke. 2007 Dec;38(12):3237-44. Epub 2007 Nov 1.

PMID:
17975099
17.

Three new PAX6 mutations including one causing an unusual ophthalmic phenotype associated with neurodevelopmental abnormalities.

Dansault A, David G, Schwartz C, Jaliffa C, Vieira V, de la Houssaye G, Bigot K, Catin F, Tattu L, Chopin C, Halimi P, Roche O, Van Regemorter N, Munier F, Schorderet D, Dufier JL, Marsac C, Ricquier D, Menasche M, Penfornis A, Abitbol M.

Mol Vis. 2007 Apr 2;13:511-23.

18.

New VMD2 gene mutations identified in patients affected by Best vitelliform macular dystrophy.

Marchant D, Yu K, Bigot K, Roche O, Germain A, Bonneau D, Drouin-Garraud V, Schorderet DF, Munier F, Schmidt D, Le Neindre P, Marsac C, Menasche M, Dufier JL, Fischmeister R, Hartzell C, Abitbol M.

J Med Genet. 2007 Mar;44(3):e70. Epub 2007 Feb 7.

19.

Refeeding and insulin activate the AKT/p70S6 kinase pathway without affecting IRS1 tyrosine phosphorylation in chicken muscle.

Duchêne S, Métayer S, Audouin E, Bigot K, Dupont J, Tesseraud S.

Domest Anim Endocrinol. 2008 Jan;34(1):1-13. Epub 2006 Sep 25.

PMID:
17029674
20.

Regulation of protein metabolism by insulin: value of different approaches and animal models.

Tesseraud S, Métayer S, Duchêne S, Bigot K, Grizard J, Dupont J.

Domest Anim Endocrinol. 2007 Aug;33(2):123-42. Epub 2006 Jun 30. Review.

PMID:
16876379
21.

Mechanisms involved in the nutritional regulation of mRNA translation: features of the avian model.

Tesseraud S, Abbas M, Duchene S, Bigot K, Vaudin P, Dupont J.

Nutr Res Rev. 2006 Jun;19(1):104-16. doi: 10.1079/NRR2006120.

PMID:
19079879
22.

Early post-hatching starvation delays p70 S6 kinase activation in the muscle of neonatal chicks.

Bigot K, Taouis M, Picard M, Tesseraud S.

Br J Nutr. 2003 Dec;90(6):1023-9.

PMID:
14641961
23.

Is ribosomal capacity a potential metabolic marker of muscle development? Measurement by muscular biopsy.

Quentin M, Bigot K, Tesseraud S, Boirie Y, Bouvarel I, Picard M.

Poult Sci. 2003 Oct;82(10):1530-5.

PMID:
14601728
24.

Effects of delayed feed intake on body, intestine, and muscle development in neonate broilers.

Bigot K, Mignon-Grasteau S, Picard M, Tesseraud S.

Poult Sci. 2003 May;82(5):781-8.

PMID:
12762401
25.
26.

Refeeding and insulin regulate S6K1 activity in chicken skeletal muscles.

Bigot K, Taouis M, Tesseraud S.

J Nutr. 2003 Feb;133(2):369-73.

PMID:
12566469
27.

Early-age thermal conditioning reduces uncoupling protein messenger RNA expression in pectoral muscle of broiler chicks at seven days of age.

Taouis M, De Basilio V, Mignon-Grasteau S, Crochet S, Bouchot C, Bigot K, Collin A, Picard M.

Poult Sci. 2002 Nov;81(11):1640-3.

PMID:
12455589
28.

Establishment of an in vitro reporter gene assay for developmental cardiac toxicity.

Bremer S, Worth AP, Paparella M, Bigot K, Kolossov E, Fleischmann BK, Hescheler J, Balls M.

Toxicol In Vitro. 2001 Jun;15(3):215-23.

PMID:
11377094
29.

Comparison of hepatic and renal drug-metabolising enzyme activities in sheep given single or two-fold challenge infections with Fasciola hepatica.

Calléja C, Bigot K, Eeckhoutte C, Sibille P, Boulard C, Galtier P.

Int J Parasitol. 2000 Jul;30(8):953-8.

PMID:
10927086
30.
31.
32.

The Relative Semi-quantification of mRNA Expression as a Useful Toxicological Endpoint for the Identification of Embryotoxic/Teratogenic Substances.

Bigot K, de Lange J, Archer G, Clothier R, Bremer S.

Toxicol In Vitro. 1999 Aug-Oct;13(4-5):619-23.

PMID:
20654525

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