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Use of 3D Models in the Surgical Decision-Making Process in a Case of Double-Outlet Right Ventricle With Multiple Ventricular Septal Defects.

Shearn AIU, Yeong M, Richard M, Ordoñez MV, Pinchbeck H, Milano EG, Hayes A, Caputo M, Biglino G.

Front Pediatr. 2019 Aug 20;7:330. doi: 10.3389/fped.2019.00330. eCollection 2019.


Beyond apical ballooning: computational modelling reveals morphological features of Takotsubo cardiomyopathy.

Pontecorboli G, Biglino G, Milano EG, Sophocleous F, Biffi B, Dastidar AG, Schievano S, Di Mario C, Bucciarelli-Ducci C.

Comput Methods Biomech Biomed Engin. 2019 Nov;22(14):1103-1106. doi: 10.1080/10255842.2019.1632836. Epub 2019 Jul 3.


Three-dimensional printing in congenital heart disease: Considerations on training and clinical implementation from a teaching session.

Biglino G, Milano EG, Capelli C, Wray J, Shearn AI, Caputo M, Bucciarelli-Ducci C, Taylor AM, Schievano S.

Int J Artif Organs. 2019 Oct;42(10):595-599. doi: 10.1177/0391398819849074. Epub 2019 May 20.


MicroRNAs as potential biomarkers in congenital heart surgery.

Stoica SC, Dorobantu DM, Vardeu A, Biglino G, Ford KL, Bruno DV, Zakkar M, Mumford A, Angelini GD, Caputo M, Emanueli C.

J Thorac Cardiovasc Surg. 2019 Apr 4. pii: S0022-5223(19)30740-8. doi: 10.1016/j.jtcvs.2019.03.062. [Epub ahead of print]


Long term cardiovascular magnetic resonance phenotyping of anthracycline cardiomyopathy.

Harries I, Biglino G, Baritussio A, De Garate E, Dastidar A, Plana JC, Bucciarelli-Ducci C.

Int J Cardiol. 2019 Oct 1;292:248-252. doi: 10.1016/j.ijcard.2019.04.026. Epub 2019 Apr 10.


Towards a narrative cardiology: exploring, holding and re-presenting narratives of heart disease.

Biglino G, Bucciarelli-Ducci C, Caputo M, Carel H, Hurwitz B, Layton S, Stretton-Downes J, Tiwari N, Wray J, Vaccarella M.

Cardiovasc Diagn Ther. 2019 Feb;9(1):73-77. doi: 10.21037/cdt.2018.11.03. No abstract available.


Evaluating 3D-printed models of coronary anomalies: a survey among clinicians and researchers at a university hospital in the UK.

Lee M, Moharem-Elgamal S, Beckingham R, Hamilton M, Manghat N, Milano EG, Bucciarelli-Ducci C, Caputo M, Biglino G.

BMJ Open. 2019 Mar 8;9(3):e025227. doi: 10.1136/bmjopen-2018-025227.


Prognostic Role of CMR and Conventional Risk Factors in Myocardial Infarction With Nonobstructed Coronary Arteries.

Dastidar AG, Baritussio A, De Garate E, Drobni Z, Biglino G, Singhal P, Milano EG, Angelini GD, Dorman S, Strange J, Johnson T, Bucciarelli-Ducci C.

JACC Cardiovasc Imaging. 2019 Oct;12(10):1973-1982. doi: 10.1016/j.jcmg.2018.12.023. Epub 2019 Feb 13.


Arrhythmogenic right ventricular cardiomyopathy (ARVC) mimics: the knot unravelled by cardiovascular MRI.

Amadu AM, Baritussio A, Dastidar AG, De Garate E, Rodrigues JCL, Biglino G, Lyen S, Diab I, Duncan E, Nisbet A, Thomas G, Angelini GD, Bucciarelli-Ducci C.

Clin Radiol. 2019 Mar;74(3):228-234. doi: 10.1016/j.crad.2018.12.002. Epub 2019 Jan 23.


Aortic morphological variability in patients with bicuspid aortic valve and aortic coarctation.

Sophocleous F, Biffi B, Milano EG, Bruse J, Caputo M, Rajakaruna C, Schievano S, Emanueli C, Bucciarelli-Ducci C, Biglino G.

Eur J Cardiothorac Surg. 2019 Apr 1;55(4):704-713. doi: 10.1093/ejcts/ezy339.


BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase).

Descamps B, Saif J, Benest AV, Biglino G, Bates DO, Chamorro-Jorganes A, Emanueli C.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2117-2125. doi: 10.1161/ATVBAHA.118.311400.


'Making the Invisible Visible': an audience response to an art installation representing the complexity of congenital heart disease and heart transplantation.

Biglino G, Layton S, Lee M, Sophocleous F, Hall S, Wray J.

Med Humanit. 2018 Oct 18. pii: medhum-2018-011466. doi: 10.1136/medhum-2018-011466. [Epub ahead of print]


Current and future applications of 3D printing in congenital cardiology and cardiac surgery.

Milano EG, Capelli C, Wray J, Biffi B, Layton S, Lee M, Caputo M, Taylor AM, Schievano S, Biglino G.

Br J Radiol. 2019 Feb;92(1094):20180389. doi: 10.1259/bjr.20180389. Epub 2018 Nov 1.


Wave intensity analysis in the internal carotid artery of hypertensive subjects using phase-contrast MR angiography and preliminary assessment of the effect of vessel morphology on wave dynamics.

Neumann S, Sophocleous F, Kobetic MD, Hart EC, Nightingale AK, Parker KH, Hamilton MK, Biglino G.

Physiol Meas. 2018 Oct 19;39(10):104003. doi: 10.1088/1361-6579/aadfc5.


Applications of 3D printing in paediatric cardiology: its potential and the need for gathering evidence.

Biglino G, Milano EG.

Transl Pediatr. 2018 Jul;7(3):219-221. doi: 10.21037/tp.2018.07.02. No abstract available.


Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product.

MacAskill MG, Saif J, Condie A, Jansen MA, MacGillivray TJ, Tavares AAS, Fleisinger L, Spencer HL, Besnier M, Martin E, Biglino G, Newby DE, Hadoke PWF, Mountford JC, Emanueli C, Baker AH.

Mol Ther. 2018 Jul 5;26(7):1669-1684. doi: 10.1016/j.ymthe.2018.03.017. Epub 2018 Mar 28.


Enlightening the Association between Bicuspid Aortic Valve and Aortopathy.

Sophocleous F, Milano EG, Pontecorboli G, Chivasso P, Caputo M, Rajakaruna C, Bucciarelli-Ducci C, Emanueli C, Biglino G.

J Cardiovasc Dev Dis. 2018 Apr 19;5(2). pii: E21. doi: 10.3390/jcdd5020021. Review.


Fortune favours the brave: composite first-person narrative of adolescents with congenital heart disease.

Biglino G, Layton S, Leaver LK, Wray J.

BMJ Paediatr Open. 2017 Nov 17;1(1):e000186. doi: 10.1136/bmjpo-2017-000186. eCollection 2017.


Beyond Heart Symbolism: Artistic Representation of Narratives of Congenital Heart Disease.

Biglino G, Layton S, Wray J.

JAMA. 2017 Nov 14;318(18):1740-1742. doi: 10.1001/jama.2017.14285. No abstract available.


The Perception of a Three-Dimensional-Printed Heart Model from the Perspective of Different Stakeholders: A Complex Case of Truncus Arteriosus.

Biglino G, Moharem-Elgamal S, Lee M, Tulloh R, Caputo M.

Front Pediatr. 2017 Sep 28;5:209. doi: 10.3389/fped.2017.00209. eCollection 2017.


Editorial: Ventricular Mechanics in Congenital Heart Disease.

Biglino G, de Vecchi A.

Front Pediatr. 2017 May 31;5:129. doi: 10.3389/fped.2017.00129. eCollection 2017. No abstract available.


The landscape of congenital heart disease.

Biglino G.

Cardiovasc Diagn Ther. 2017 Apr;7(Suppl 1):S55-S56. doi: 10.21037/cdt.2017.03.08. No abstract available.


Utility of Cardiovascular Magnetic Resonance-Derived Wave Intensity Analysis As a Marker of Ventricular Function in Children with Heart Failure and Normal Ejection Fraction.

Ntsinjana HN, Chung R, Ciliberti P, Muthurangu V, Schievano S, Marek J, Parker KH, Taylor AM, Biglino G.

Front Pediatr. 2017 Apr 3;5:65. doi: 10.3389/fped.2017.00065. eCollection 2017.


Out of hospital cardiac arrest survivors with inconclusive coronary angiogram: Impact of cardiovascular magnetic resonance on clinical management and decision-making.

Baritussio A, Zorzi A, Ghosh Dastidar A, Susana A, Mattesi G, Rodrigues JCL, Biglino G, Scatteia A, De Garate E, Strange J, Cacciavillani L, Iliceto S, Nisbet A, Angelini GD, Corrado D, Perazzolo Marra M, Bucciarelli-Ducci C.

Resuscitation. 2017 Jul;116:91-97. doi: 10.1016/j.resuscitation.2017.03.039. Epub 2017 Apr 1.


Piloting the Use of Patient-Specific Cardiac Models as a Novel Tool to Facilitate Communication During Cinical Consultations.

Biglino G, Koniordou D, Gasparini M, Capelli C, Leaver LK, Khambadkone S, Schievano S, Taylor AM, Wray J.

Pediatr Cardiol. 2017 Apr;38(4):813-818. doi: 10.1007/s00246-017-1586-9. Epub 2017 Feb 18.


A method to implement the reservoir-wave hypothesis using phase-contrast magnetic resonance imaging.

Gray RD, Parker KH, Quail MA, Taylor AM, Biglino G.

MethodsX. 2016 Aug 25;3:508-512. doi: 10.1016/j.mex.2016.08.004. eCollection 2016.


A Mock Circulatory System Incorporating a Compliant 3D-Printed Anatomical Model to Investigate Pulmonary Hemodynamics.

Knoops PGM, Biglino G, Hughes AD, Parker KH, Xu L, Schievano S, Torii R.

Artif Organs. 2017 Jul;41(7):637-646. doi: 10.1111/aor.12809. Epub 2016 Dec 7.


Modulating microRNAs in cardiac surgery patients: Novel therapeutic opportunities?

Biglino G, Caputo M, Rajakaruna C, Angelini G, van Rooij E, Emanueli C.

Pharmacol Ther. 2017 Feb;170:192-204. doi: 10.1016/j.pharmthera.2016.11.004. Epub 2016 Nov 27. Review.


Computational modelling for congenital heart disease: how far are we from clinical translation?

Biglino G, Capelli C, Bruse J, Bosi GM, Taylor AM, Schievano S.

Heart. 2017 Jan 15;103(2):98-103. doi: 10.1136/heartjnl-2016-310423. Epub 2016 Oct 25. Review.


How successful is successful? Aortic arch shape after successful aortic coarctation repair correlates with left ventricular function.

Bruse JL, Khushnood A, McLeod K, Biglino G, Sermesant M, Pennec X, Taylor AM, Hsia TY, Schievano S; Modeling of Congenital Hearts Alliance Collaborative Group.

J Thorac Cardiovasc Surg. 2017 Feb;153(2):418-427. doi: 10.1016/j.jtcvs.2016.09.018. Epub 2016 Sep 22.


Use of 3D models of congenital heart disease as an education tool for cardiac nurses.

Biglino G, Capelli C, Koniordou D, Robertshaw D, Leaver LK, Schievano S, Taylor AM, Wray J.

Congenit Heart Dis. 2017 Jan;12(1):113-118. doi: 10.1111/chd.12414. Epub 2016 Sep 26.


Looks Do Matter! Aortic Arch Shape After Hypoplastic Left Heart Syndrome Palliation Correlates With Cavopulmonary Outcomes.

Bruse JL, Cervi E, McLeod K, Biglino G, Sermesant M, Pennec X, Taylor AM, Schievano S, Hsia TY; Modeling of Congenital Hearts Alliance (MOCHA) Collaborative Group.

Ann Thorac Surg. 2017 Feb;103(2):645-654. doi: 10.1016/j.athoracsur.2016.06.041. Epub 2016 Sep 1.


Can finite element models of ballooning procedures yield mechanical response of the cardiovascular site to overexpansion?

Bosi GM, Biffi B, Biglino G, Lintas V, Jones R, Tzamtzis S, Burriesci G, Migliavacca F, Khambadkone S, Taylor AM, Schievano S.

J Biomech. 2016 Sep 6;49(13):2778-2784. doi: 10.1016/j.jbiomech.2016.06.021. Epub 2016 Jun 23.


A statistical shape modelling framework to extract 3D shape biomarkers from medical imaging data: assessing arch morphology of repaired coarctation of the aorta.

Bruse JL, McLeod K, Biglino G, Ntsinjana HN, Capelli C, Hsia TY, Sermesant M, Pennec X, Taylor AM, Schievano S; Modeling of Congenital Hearts Alliance (MOCHA) Collaborative Group.

BMC Med Imaging. 2016 May 31;16(1):40. doi: 10.1186/s12880-016-0142-z.


Numerical model of a valvuloplasty balloon: in vitro validation in a rapid-prototyped phantom.

Biffi B, Bosi GM, Lintas V, Jones R, Tzamtzis S, Burriesci G, Migliavacca F, Taylor AM, Schievano S, Biglino G.

Biomed Eng Online. 2016 Apr 12;15:37. doi: 10.1186/s12938-016-0155-4.


In Vitro Validation of a Multiscale Patient-Specific Norwood Palliation Model.

Hang T, Giardini A, Biglino G, Conover T, Figliola RS; MOCHA Collaborative Group.

ASAIO J. 2016 May-Jun;62(3):317-24. doi: 10.1097/MAT.0000000000000336.


Using 4D Cardiovascular Magnetic Resonance Imaging to Validate Computational Fluid Dynamics: A Case Study.

Biglino G, Cosentino D, Steeden JA, De Nova L, Castelli M, Ntsinjana H, Pennati G, Taylor AM, Schievano S.

Front Pediatr. 2015 Dec 14;3:107. doi: 10.3389/fped.2015.00107. eCollection 2015.


3D-manufactured patient-specific models of congenital heart defects for communication in clinical practice: feasibility and acceptability.

Biglino G, Capelli C, Wray J, Schievano S, Leaver LK, Khambadkone S, Giardini A, Derrick G, Jones A, Taylor AM.

BMJ Open. 2015 Apr 30;5(4):e007165. doi: 10.1136/bmjopen-2014-007165.


Involving patients, families and medical staff in the evaluation of 3D printing models of congenital heart disease.

Biglino G, Capelli C, Leaver LK, Schievano S, Taylor AM, Wray J.

Commun Med. 2015;12(2-3):157-69.


Integration of clinical data collected at different times for virtual surgery in single ventricle patients: a case study.

Corsini C, Baker C, Baretta A, Biglino G, Hlavacek AM, Hsia TY, Kung E, Marsden A, Migliavacca F, Vignon-Clementel I, Pennati G; Modeling of Congenital Hearts Alliance (MOCHA) Investigators.

Ann Biomed Eng. 2015 Jun;43(6):1310-20. doi: 10.1007/s10439-014-1113-6. Epub 2014 Oct 25.


Ventriculovascular interactions late after atrial and arterial repair of transposition of the great arteries.

Biglino G, Ntsinjana H, Plymen C, Tann O, Giardini A, Derrick G, Parker KH, Tsang V, Schievano S, Taylor AM.

J Thorac Cardiovasc Surg. 2014 Dec;148(6):2627-33. doi: 10.1016/j.jtcvs.2014.07.072. Epub 2014 Aug 5.


3D morphometric analysis of the arterial switch operation using in vivo MRI data.

Ntsinjana HN, Capelli C, Biglino G, Cook AC, Tann O, Derrick G, Taylor AM, Schievano S.

Clin Anat. 2014 Nov;27(8):1212-22. doi: 10.1002/ca.22458. Epub 2014 Aug 26.


Computational models of aortic coarctation in hypoplastic left heart syndrome: considerations on validation of a detailed 3D model.

Biglino G, Corsini C, Schievano S, Dubini G, Giardini A, Hsia TY, Pennati G, Taylor AM; Mocha Collaborative Group.

Int J Artif Organs. 2014 May;37(5):371-81. doi: 10.5301/ijao.5000332. Epub 2014 May 30.


The effect of modified Blalock-Taussig shunt size and coarctation severity on coronary perfusion after the Norwood operation.

Corsini C, Biglino G, Schievano S, Hsia TY, Migliavacca F, Pennati G, Taylor AM; MOCHA Collaborative Group.

Ann Thorac Surg. 2014 Aug;98(2):648-54. doi: 10.1016/j.athoracsur.2014.04.047. Epub 2014 Jun 4.


Ventriculoarterial coupling in palliated hypoplastic left heart syndrome: Noninvasive assessment of the effects of surgical arch reconstruction and shunt type.

Biglino G, Giardini A, Ntsinjana HN, Schievano S, Hsia TY, Taylor AM; Modeling of Congenital Hearts Alliance Collaborative Group.

J Thorac Cardiovasc Surg. 2014 Oct;148(4):1526-33. doi: 10.1016/j.jtcvs.2014.02.012. Epub 2014 Feb 10.


Modeling single ventricle physiology: review of engineering tools to study first stage palliation of hypoplastic left heart syndrome.

Biglino G, Giardini A, Hsia TY, Figliola R, Taylor AM, Schievano S; MOCHA Collaborative Group.

Front Pediatr. 2013 Oct 30;1:31. doi: 10.3389/fped.2013.00031. Review.


Aortic arch shape is not associated with hypertensive response to exercise in patients with repaired congenital heart diseases.

Ntsinjana HN, Biglino G, Capelli C, Tann O, Giardini A, Derrick G, Schievano S, Taylor AM.

J Cardiovasc Magn Reson. 2013 Nov 12;15:101. doi: 10.1186/1532-429X-15-101.


An integrated approach to patient-specific predictive modeling for single ventricle heart palliation.

Corsini C, Baker C, Kung E, Schievano S, Arbia G, Baretta A, Biglino G, Migliavacca F, Dubini G, Pennati G, Marsden A, Vignon-Clementel I, Taylor A, Hsia TY, Dorfman A; Modeling of Congenital Hearts Alliance (MOCHA) Investigators.

Comput Methods Biomech Biomed Engin. 2014;17(14):1572-89. doi: 10.1080/10255842.2012.758254. Epub 2013 Jan 23.


Rapid prototyping compliant arterial phantoms for in-vitro studies and device testing.

Biglino G, Verschueren P, Zegels R, Taylor AM, Schievano S.

J Cardiovasc Magn Reson. 2013 Jan 16;15:2. doi: 10.1186/1532-429X-15-2.


Implementing the Sano modification in an experimental model of first-stage palliation of hypoplastic left heart syndrome.

Biglino G, Giardini A, Baker C, Figliola RS, Hsia TY, Taylor AM, Schievano S; MOCHA Collaborative Group.

ASAIO J. 2013 Jan-Feb;59(1):86-9. doi: 10.1097/MAT.0b013e3182768b7f.


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