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Items: 46

1.

Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.

Kirkling ME, Cytlak U, Lau CM, Lewis KL, Resteu A, Khodadadi-Jamayran A, Siebel CW, Salmon H, Merad M, Tsirigos A, Collin M, Bigley V, Reizis B.

Cell Rep. 2018 Jun 19;23(12):3658-3672.e6. doi: 10.1016/j.celrep.2018.05.068.

2.

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans.

Cytlak U, Resteu A, Bogaert D, Kuehn HS, Altmann T, Gennery A, Jackson G, Kumanovics A, Voelkerding KV, Prader S, Dullaers M, Reichenbach J, Hill H, Haerynck F, Rosenzweig SD, Collin M, Bigley V.

Nat Commun. 2018 Mar 27;9(1):1239. doi: 10.1038/s41467-018-02977-8.

3.

Human dendritic cell immunodeficiencies.

Bigley V, Cytlak U, Collin M.

Semin Cell Dev Biol. 2019 Feb;86:50-61. doi: 10.1016/j.semcdb.2018.02.020. Epub 2018 Feb 23. Review.

PMID:
29452225
4.

Human dendritic cell subsets: an update.

Collin M, Bigley V.

Immunology. 2018 May;154(1):3-20. doi: 10.1111/imm.12888. Epub 2018 Feb 27. Review.

5.

In vivo T-depleted reduced-intensity transplantation for GATA2-related immune dysfunction.

Tholouli E, Sturgess K, Dickinson RE, Gennery A, Cant AJ, Jackson G, Lordan J, Hambleton S, Slatter MA, Bigley V, Collin M.

Blood. 2018 Mar 22;131(12):1383-1387. doi: 10.1182/blood-2017-10-811489. Epub 2018 Jan 2. No abstract available.

6.

Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency.

Fox TA, Chakraverty R, Burns S, Carpenter B, Thomson K, Lowe D, Fielding A, Peggs K, Kottaridis P, Uttenthal B, Bigley V, Buckland M, Grandage V, Denovan S, Grace S, Dahlstrom J, Workman S, Symes A, Mackinnon S, Hough R, Morris E.

Blood. 2018 Feb 22;131(8):917-931. doi: 10.1182/blood-2017-09-807487. Epub 2017 Dec 26.

7.

Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.

Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M.

J Allergy Clin Immunol. 2018 Jun;141(6):2234-2248. doi: 10.1016/j.jaci.2017.08.044. Epub 2017 Nov 8.

8.

A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.

Bogaert DJ, Kuehn HS, Bonroy C, Calvo KR, Dehoorne J, Vanlander AV, De Bruyne M, Cytlak U, Bigley V, De Baets F, De Baere E, Rosenzweig SD, Haerynck F, Dullaers M.

J Allergy Clin Immunol. 2018 Jan;141(1):432-435.e7. doi: 10.1016/j.jaci.2017.08.019. Epub 2017 Sep 18. No abstract available.

PMID:
28927821
9.

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2.

McGovern N, Shin A, Low G, Low D, Duan K, Yao LJ, Msallam R, Low I, Shadan NB, Sumatoh HR, Soon E, Lum J, Mok E, Hubert S, See P, Kunxiang EH, Lee YH, Janela B, Choolani M, Mattar CNZ, Fan Y, Lim TKH, Chan DKH, Tan KK, Tam JKC, Schuster C, Elbe-Bürger A, Wang XN, Bigley V, Collin M, Haniffa M, Schlitzer A, Poidinger M, Albani S, Larbi A, Newell EW, Chan JKY, Ginhoux F.

Nature. 2017 Jun 29;546(7660):662-666. doi: 10.1038/nature22795. Epub 2017 Jun 14.

PMID:
28614294
10.

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation.

Patel AA, Zhang Y, Fullerton JN, Boelen L, Rongvaux A, Maini AA, Bigley V, Flavell RA, Gilroy DW, Asquith B, Macallan D, Yona S.

J Exp Med. 2017 Jul 3;214(7):1913-1923. doi: 10.1084/jem.20170355. Epub 2017 Jun 12.

11.

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.

Milne P, Bigley V, Bacon CM, Néel A, McGovern N, Bomken S, Haniffa M, Diamond EL, Durham BH, Visser J, Hunt D, Gunawardena H, Macheta M, McClain KL, Allen C, Abdel-Wahab O, Collin M.

Blood. 2017 Jul 13;130(2):167-175. doi: 10.1182/blood-2016-12-757823. Epub 2017 May 16.

12.

Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts.

Green K, Pearce K, Sellar RS, Jardine L, Nicolson PLR, Nagra S, Bigley V, Jackson G, Dickinson AM, Thomson K, Mackinnon S, Craddock C, Peggs KS, Collin M.

Biol Blood Marrow Transplant. 2017 May;23(5):805-812. doi: 10.1016/j.bbmt.2017.02.007. Epub 2017 Feb 14.

13.

Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells.

Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang SC, Allan DS, Davidson-Moncada JK, Dickinson RE, Holmes TD, Hsu AP, Townsley D, Winkler T, Wang W, Aukrust P, Nordøy I, Calvo KR, Holland SM, Collin M, Dunbar CE, Bryceson YT.

Blood. 2017 Apr 6;129(14):1927-1939. doi: 10.1182/blood-2016-08-734236. Epub 2017 Feb 16.

14.

Early Molecular Stratification of High-risk Primary Biliary Cholangitis.

Hardie C, Green K, Jopson L, Millar B, Innes B, Pagan S, Tiniakos D, Dyson J, Haniffa M, Bigley V, Jones DE, Brain J, Walker LJ.

EBioMedicine. 2016 Dec;14:65-73. doi: 10.1016/j.ebiom.2016.11.021. Epub 2016 Nov 21.

15.

Biallelic mutations in IRF8 impair human NK cell maturation and function.

Mace EM, Bigley V, Gunesch JT, Chinn IK, Angelo LS, Care MA, Maisuria S, Keller MD, Togi S, Watkin LB, LaRosa DF, Jhangiani SN, Muzny DM, Stray-Pedersen A, Coban Akdemir Z, Smith JB, Hernández-Sanabria M, Le DT, Hogg GD, Cao TN, Freud AG, Szymanski EP, Savic S, Collin M, Cant AJ, Gibbs RA, Holland SM, Caligiuri MA, Ozato K, Paust S, Doody GM, Lupski JR, Orange JS.

J Clin Invest. 2017 Jan 3;127(1):306-320. doi: 10.1172/JCI86276. Epub 2016 Nov 28.

16.

Targeted treatment of brainstem neurohistiocytosis guided by urinary cell-free DNA.

Hunt D, Milne P, Fernandes P, Bigley V, Collin M.

Neurol Neuroimmunol Neuroinflamm. 2016 Nov 3;4(1):e299. eCollection 2017 Jan.

17.

Dendritic cell analysis in primary immunodeficiency.

Bigley V, Barge D, Collin M.

Curr Opin Allergy Clin Immunol. 2016 Dec;16(6):530-540. Review.

18.

Monocyte, Macrophage, and Dendritic Cell Development: the Human Perspective.

Collin M, Bigley V.

Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.MCHD-0015-2015. Review.

PMID:
27780016
19.

Timely follow-up of a GATA2 deficiency patient allows successful treatment.

Ciullini Mannurita S, Vignoli M, Colarusso G, Tucci F, Veltroni M, Frenos S, Tintori V, Aricò M, Bigley V, Collin M, Favre C, Gambineri E.

J Allergy Clin Immunol. 2016 Nov;138(5):1480-1483.e4. doi: 10.1016/j.jaci.2016.06.004. Epub 2016 Jul 29. No abstract available.

PMID:
27481672
20.

Single-gene association between GATA-2 and autoimmune hepatitis: A novel genetic insight highlighting immunologic pathways to disease.

Webb G, Chen YY, Li KK, Neil D, Oo YH, Richter A, Bigley V, Collin M, Adams DH, Hirschfield GM.

J Hepatol. 2016 May;64(5):1190-1193. doi: 10.1016/j.jhep.2016.01.017. Epub 2016 Jan 23.

21.

Cell(s) of Origin of Langerhans Cell Histiocytosis.

Collin M, Bigley V, McClain KL, Allen CE.

Hematol Oncol Clin North Am. 2015 Oct;29(5):825-38. doi: 10.1016/j.hoc.2015.06.003. Epub 2015 Aug 20. Review.

22.

Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.

Holzinger D, Fassl SK, de Jager W, Lohse P, Röhrig UF, Gattorno M, Omenetti A, Chiesa S, Schena F, Austermann J, Vogl T, Kuhns DB, Holland SM, Rodríguez-Gallego C, López-Almaraz R, Arostegui JI, Colino E, Roldan R, Fessatou S, Isidor B, Poignant S, Ito K, Epple HJ, Bernstein JA, Jeng M, Frankovich J, Lionetti G, Church JA, Ong PY, LaPlant M, Abinun M, Skinner R, Bigley V, Sachs UJ, Hinze C, Hoppenreijs E, Ehrchen J, Foell D, Chae JJ, Ombrello A, Aksentijevich I, Sunderkoetter C, Roth J.

J Allergy Clin Immunol. 2015 Nov;136(5):1337-45. doi: 10.1016/j.jaci.2015.04.016. Epub 2015 May 27.

PMID:
26025129
23.

Human mononuclear phagocyte system reunited.

Haniffa M, Bigley V, Collin M.

Semin Cell Dev Biol. 2015 May;41:59-69. doi: 10.1016/j.semcdb.2015.05.004. Epub 2015 May 15. Review.

PMID:
25986054
24.

Haematopoietic and immune defects associated with GATA2 mutation.

Collin M, Dickinson R, Bigley V.

Br J Haematol. 2015 Apr;169(2):173-87. doi: 10.1111/bjh.13317. Epub 2015 Feb 23. Review.

25.

Population of Monocyte-Derived Macrophages.

McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Larbi A, Wasan PS, Kaibo D, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M.

Immunity. 2015 Feb 17;42(2):391. doi: 10.1016/j.immuni.2015.01.018. Epub 2015 Feb 17. No abstract available.

26.

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Clausen BE, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE.

J Exp Med. 2015 Feb 9;212(2):281. doi: 10.1084/jem.2013097701202015c. Epub 2015 Feb 2. No abstract available.

27.

A comparative study of reduced dose alemtuzumab in matched unrelated donor and related donor reduced intensity transplants.

Jardine L, Publicover A, Bigley V, Hale G, Pearce K, Dickinson A, Jackson G, Collin M.

Br J Haematol. 2015 Mar;168(6):874-81. doi: 10.1111/bjh.13239. Epub 2015 Jan 29.

28.

Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells.

Bigley V, McGovern N, Milne P, Dickinson R, Pagan S, Cookson S, Haniffa M, Collin M.

J Leukoc Biol. 2015 Apr;97(4):627-34. doi: 10.1189/jlb.1HI0714-351R. Epub 2014 Dec 16.

29.

CD1c+ blood dendritic cells have Langerhans cell potential.

Milne P, Bigley V, Gunawan M, Haniffa M, Collin M.

Blood. 2015 Jan 15;125(3):470-3. doi: 10.1182/blood-2014-08-593582. Epub 2014 Oct 28.

30.

Human dermal CD14⁺ cells are a transient population of monocyte-derived macrophages.

McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Larbi A, Wasan PS, Duan K, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M.

Immunity. 2014 Sep 18;41(3):465-477. doi: 10.1016/j.immuni.2014.08.006. Epub 2014 Sep 4. Erratum in: Immunity. 2015 Feb 17;42(2):391. Saavedra, Diego Miranda [corrected to Miranda-Saavedra, Diego].

31.

Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation.

Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P.

Blood. 2014 Sep 18;124(12):1894-904.

32.

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE.

J Exp Med. 2014 Apr 7;211(4):669-83. doi: 10.1084/jem.20130977. Epub 2014 Mar 17. Erratum in: J Exp Med. 2015 Feb 9;212(2):281.

33.

Rapid detection of dendritic cell and monocyte disorders using CD4 as a lineage marker of the human peripheral blood antigen-presenting cell compartment.

Jardine L, Barge D, Ames-Draycott A, Pagan S, Cookson S, Spickett G, Haniffa M, Collin M, Bigley V.

Front Immunol. 2013 Dec 27;4:495. doi: 10.3389/fimmu.2013.00495. eCollection 2013.

34.

The evolution of cellular deficiency in GATA2 mutation.

Dickinson RE, Milne P, Jardine L, Zandi S, Swierczek SI, McGovern N, Cookson S, Ferozepurwalla Z, Langridge A, Pagan S, Gennery A, Heiskanen-Kosma T, Hämäläinen S, Seppänen M, Helbert M, Tholouli E, Gambineri E, Reykdal S, Gottfreðsson M, Thaventhiran JE, Morris E, Hirschfield G, Richter AG, Jolles S, Bacon CM, Hambleton S, Haniffa M, Bryceson Y, Allen C, Prchal JT, Dick JE, Bigley V, Collin M.

Blood. 2014 Feb 6;123(6):863-74. doi: 10.1182/blood-2013-07-517151. Epub 2013 Dec 17.

35.

Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts.

Hügle T, O'Reilly S, Simpson R, Kraaij MD, Bigley V, Collin M, Krippner-Heidenreich A, van Laar JM.

Arthritis Rheum. 2013 Feb;65(2):481-91. doi: 10.1002/art.37738.

36.

Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.

Haniffa M, Shin A, Bigley V, McGovern N, Teo P, See P, Wasan PS, Wang XN, Malinarich F, Malleret B, Larbi A, Tan P, Zhao H, Poidinger M, Pagan S, Cookson S, Dickinson R, Dimmick I, Jarrett RF, Renia L, Tam J, Song C, Connolly J, Chan JK, Gehring A, Bertoletti A, Collin M, Ginhoux F.

Immunity. 2012 Jul 27;37(1):60-73. doi: 10.1016/j.immuni.2012.04.012. Epub 2012 Jul 12.

37.

Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands.

Jardine L, Hambleton S, Bigley V, Pagan S, Wang XN, Collin M.

Leuk Lymphoma. 2013 Jan;54(1):167-73. doi: 10.3109/10428194.2012.708026. Epub 2012 Sep 8.

PMID:
22742576
38.

Human dendritic cell deficiency: the missing ID?

Collin M, Bigley V, Haniffa M, Hambleton S.

Nat Rev Immunol. 2011 Aug 19;11(9):575-83. doi: 10.1038/nri3046. Review.

PMID:
21852794
39.

Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome.

Bigley V, Collin M.

Haematologica. 2011 Aug;96(8):1081-3. doi: 10.3324/haematol.2011.048355. No abstract available.

40.

Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.

Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M.

Blood. 2011 Sep 8;118(10):2656-8. doi: 10.1182/blood-2011-06-360313. Epub 2011 Jul 15.

41.

IRF8 mutations and human dendritic-cell immunodeficiency.

Hambleton S, Salem S, Bustamante J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez L, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, Alsina L, Zumwalt TJ, Kong XF, Kumararatne D, Butler K, Hubeau M, Feinberg J, Al-Muhsen S, Cant A, Abel L, Chaussabel D, Doffinger R, Talesnik E, Grumach A, Duarte A, Abarca K, Moraes-Vasconcelos D, Burk D, Berghuis A, Geissmann F, Collin M, Casanova JL, Gros P.

N Engl J Med. 2011 Jul 14;365(2):127-38. doi: 10.1056/NEJMoa1100066. Epub 2011 Apr 27.

42.

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M.

J Exp Med. 2011 Feb 14;208(2):227-34. doi: 10.1084/jem.20101459. Epub 2011 Jan 17.

43.

Connecting the dots: monocyte/DC and NK subsets in human peripheral blood.

Bigley V, Spence LE, Collin M.

Blood. 2010 Oct 14;116(15):2859-60. doi: 10.1182/blood-2010-05-285676. No abstract available.

44.

Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation.

Haniffa M, Ginhoux F, Wang XN, Bigley V, Abel M, Dimmick I, Bullock S, Grisotto M, Booth T, Taub P, Hilkens C, Merad M, Collin M.

J Exp Med. 2009 Feb 16;206(2):371-85. doi: 10.1084/jem.20081633. Epub 2009 Jan 26.

45.

Nephropathic cystinosis with bone marrow involvement.

Bigley V, Bhartia S, Wood A.

Br J Haematol. 2007 Jan;136(2):180. No abstract available.

PMID:
17233816
46.

Fusarium dimerum infection in a stem cell transplant recipient treated successfully with voriconazole.

Bigley VH, Duarte RF, Gosling RD, Kibbler CC, Seaton S, Potter M.

Bone Marrow Transplant. 2004 Nov;34(9):815-7.

PMID:
15361915

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