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Items: 8


Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition.

Bigley AL, Klein SK, Davies B, Williams L, Rudmann DG.

Toxicol Pathol. 2016 Jul;44(5):663-72. doi: 10.1177/0192623316629805. Epub 2016 Mar 2.


Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract.

Leeming GH, Kipar A, Hughes DJ, Bingle L, Bennett E, Moyo NA, Tripp RA, Bigley AL, Bingle CD, Sample JT, Stewart JP.

Lab Invest. 2015 Jun;95(6):610-24. doi: 10.1038/labinvest.2014.162. Epub 2014 Dec 22.


Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis.

Jones HB, Reens J, Brocklehurst SR, Betts CJ, Bickerton S, Bigley AL, Jenkins RP, Whalley NM, Morgan D, Smith DM.

Int J Exp Pathol. 2014 Feb;95(1):29-48. doi: 10.1111/iep.12066.


Expression and localization of rat aldo-keto reductases and induction of the 1B13 and 1D2 isoforms by phenolic antioxidants.

MacLeod AK, Kelly VP, Higgins LG, Kelleher MO, Price SA, Bigley AL, Betton GR, Hayes JD.

Drug Metab Dispos. 2010 Feb;38(2):341-6. doi: 10.1124/dmd.109.030544. Epub 2009 Nov 17.


AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.

Wedge SR, Kendrew J, Hennequin LF, Valentine PJ, Barry ST, Brave SR, Smith NR, James NH, Dukes M, Curwen JO, Chester R, Jackson JA, Boffey SJ, Kilburn LL, Barnett S, Richmond GH, Wadsworth PF, Walker M, Bigley AL, Taylor ST, Cooper L, Beck S, Jürgensmeier JM, Ogilvie DJ.

Cancer Res. 2005 May 15;65(10):4389-400.


Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa.

Thomson RE, Bigley AL, Foster JR, Jowsey IR, Elcombe CR, Orton TC, Hayes JD.

J Histochem Cytochem. 2004 May;52(5):653-62.


ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Chester R, Jackson JA, Boffey SJ, Valentine PJ, Curwen JO, Musgrove HL, Graham GA, Hughes GD, Thomas AP, Stokes ES, Curry B, Richmond GH, Wadsworth PF, Bigley AL, Hennequin LF.

Cancer Res. 2002 Aug 15;62(16):4645-55.

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