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Items: 1 to 50 of 58

1.

Quality of Life After Total Mesorectal Excision and Rectal Replacement: Comparing Side-to-End, Colon J-Pouch and Straight Colorectal Reconstruction in a Randomized, Phase III Trial (SAKK 40/04).

Ribi K, Marti WR, Bernhard J, Grieder F, Graf M, Gloor B, Curti G, Zuber M, Demartines N, Andrieu C, Bigler M, Hayoz S, Wehrli H, Kettelhack C, Lerf B, Fasolini F, Hamel C; Swiss group for clinical cancer research, section surgery.

Ann Surg Oncol. 2019 Jun 21. doi: 10.1245/s10434-019-07525-2. [Epub ahead of print]

PMID:
31228136
2.

The sympathomimetic agonist mirabegron did not lower JAK2-V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with myeloproliferative neoplasms: results of phase II study SAKK 33/14.

Drexler B, Passweg JR, Tzankov A, Bigler M, Theocharides AP, Cantoni N, Keller P, Stussi G, Ruefer A, Benz R, Favre G, Lundberg P, Nienhold R, Fuhrer A, Biaggi C, Manz MG, Bargetzi M, Mendez-Ferrer S, Skoda RC; Swiss Group for Clinical Cancer Research (SAKK).

Haematologica. 2019 Apr;104(4):710-716. doi: 10.3324/haematol.2018.200014. Epub 2018 Nov 8.

3.

Clinical Outcome After Rectal Replacement With Side-to-End, Colon-J-Pouch, or Straight Colorectal Anastomosis Following Total Mesorectal Excision: A Swiss Prospective, Randomized, Multicenter Trial (SAKK 40/04).

Marti WR, Curti G, Wehrli H, Grieder F, Graf M, Gloor B, Zuber M, Demartines N, Fasolini F, Lerf B, Kettelhack C, Andrieu C, Bigler M, Hayoz S, Ribi K, Hamel C; Swiss Group for Clinical Cancer Research (SAKK), Section Surgery.

Ann Surg. 2019 May;269(5):827-835. doi: 10.1097/SLA.0000000000003057.

PMID:
30252681
4.

MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources.

Marks PC, Bigler M, Alsop EB, Vigneron A, Lomans BP, De Paula R, Geissler B, Tsesmetzis N.

Database (Oxford). 2018 Jan 1;2018:1-10. doi: 10.1093/database/bay087.

5.

Immune system correlates of extensive limb swelling in response to conjugated pneumococcal vaccination.

Recher M, Hirsiger JR, Bigler MB, Iff M, Lemaître B, Scherer K, Häusermann P, Siegrist CA, Berger CT.

NPJ Vaccines. 2018 May 18;3:17. doi: 10.1038/s41541-018-0059-3. eCollection 2018.

6.

Greenland records of aerosol source and atmospheric lifetime changes from the Eemian to the Holocene.

Schüpbach S, Fischer H, Bigler M, Erhardt T, Gfeller G, Leuenberger D, Mini O, Mulvaney R, Abram NJ, Fleet L, Frey MM, Thomas E, Svensson A, Dahl-Jensen D, Kettner E, Kjaer H, Seierstad I, Steffensen JP, Rasmussen SO, Vallelonga P, Winstrup M, Wegner A, Twarloh B, Wolff K, Schmidt K, Goto-Azuma K, Kuramoto T, Hirabayashi M, Uetake J, Zheng J, Bourgeois J, Fisher D, Zhiheng D, Xiao C, Legrand M, Spolaor A, Gabrieli J, Barbante C, Kang JH, Hur SD, Hong SB, Hwang HJ, Hong S, Hansson M, Iizuka Y, Oyabu I, Muscheler R, Adolphi F, Maselli O, McConnell J, Wolff EW.

Nat Commun. 2018 Apr 16;9(1):1476. doi: 10.1038/s41467-018-03924-3.

7.

Varicella zoster virus-specific T cell responses in untreated giant cell arteritis: comment on the article by England et al.

Bigler MB, Hirsiger JR, Recher M, Mehling M, Daikeler T, Berger CT.

Arthritis Rheumatol. 2018 Feb;70(2):318-320. doi: 10.1002/art.40363. Epub 2017 Dec 20. No abstract available.

8.

NSAID treatment with meloxicam enhances peripheral stem cell mobilization in myeloma.

Jeker B, Novak U, Mansouri Taleghani B, Baerlocher GM, Seipel K, Mueller BU, Bigler M, Betticher D, Luethi JM, Farese S, Ruefer A, Pabst T.

Bone Marrow Transplant. 2018 Feb;53(2):175-179. doi: 10.1038/bmt.2017.234. Epub 2017 Oct 23.

PMID:
29058701
9.

Detection of Sp110 by Flow Cytometry and Application to Screening Patients for Veno-occlusive Disease with Immunodeficiency.

Marquardsen FA, Baldin F, Wunderer F, Al-Herz W, Mikhael R, Lefranc G, Baz Z, Rezaee F, Hanna R, Kfir-Erenfeld S, Stepensky P, Meyer B, Jauch A, Bigler MB, Burgener AV, Higgins R, Navarini AA, Church JA, Chou J, Geha R, Notarangelo LD, Hess C, Berger CT, Bloch DB, Recher M.

J Clin Immunol. 2017 Oct;37(7):707-714. doi: 10.1007/s10875-017-0431-5. Epub 2017 Aug 21.

10.

Phase I trial of the androgen receptor modulator CR1447 in breast cancer patients.

Zweifel M, Thürlimann B, Riniker S, Weder P, von Moos R, Pagani O, Bigler M, Rothgiesser KM, Pilop C, Hawle H, Brauchli P, Tapia C, Schoenfeld W, Sessa C; Swiss Group for Clinical Cancer Research (SAKK).

Endocr Connect. 2017 Oct;6(7):549-556. doi: 10.1530/EC-17-0174. Epub 2017 Aug 16.

11.

Milk replacers supplemented with either L-arginine or L-carnitine potentially improve muscle maturation of early reared low birth weight piglets from hyperprolific sows.

Madsen JG, Mueller S, Kreuzer M, Bigler MB, Silacci P, Bee G.

Animal. 2018 Jan;12(1):43-53. doi: 10.1017/S175173111700132X. Epub 2017 Jun 23.

PMID:
28641602
12.

Adjuvant treatment recommendations for patients with ER-positive/HER2-negative early breast cancer by Swiss tumor boards using the 21-gene recurrence score (SAKK 26/10).

Pestalozzi BC, Tausch C, Dedes KJ, Rochlitz C, Zimmermann S, von Moos R, Winterhalder R, Ruhstaller T, Mueller A, Buser K, Borner M, Novak U, Nussbaum CU, Seifert B, Bigler M, Bize V, Vilei SB, Rageth C, Aebi S; Swiss Group for Clinical Cancer Research (SAKK).

BMC Cancer. 2017 Apr 13;17(1):265. doi: 10.1186/s12885-017-3261-1.

13.

External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26.

Herrmann E, Naehrig D, Sassowsky M, Bigler M, Buijsen J, Ciernik I, Zwahlen D, Pellanda AF, Meister A, Brauchli P, Berardi S, Kuettel E, Dufour JF, Aebersold DM; Swiss Group for Clinical Cancer Research (SAKK).

Radiat Oncol. 2017 Jan 13;12(1):12. doi: 10.1186/s13014-016-0745-0.

14.

Characteristics of autoantibodies targeting 14-3-3 proteins and their association with clinical features in newly diagnosed giant cell arteritis.

Kistner A, Bigler MB, Glatz K, Egli SB, Baldin FS, Marquardsen FA, Mehling M, Rentsch KM, Staub D, Aschwanden M, Recher M, Daikeler T, Berger CT.

Rheumatology (Oxford). 2017 May 1;56(5):829-834. doi: 10.1093/rheumatology/kew469.

PMID:
28064210
15.

Vedolizumab as a successful treatment of CTLA-4-associated autoimmune enterocolitis.

Navarini AA, Hruz P, Berger CT, Hou TZ, Schwab C, Gabrysch A, Higgins R, Frede N, Padberg Sgier BC, Kämpe O, Burgener AV, Marquardsen F, Baldin F, Bigler M, Kistner A, Jauch A, Bignucolo O, Meyer B, Meienberg F, Mehling M, Jeker LT, Heijnen I, Daikeler TD, Gebbers JO, Grimbacher B, Sansom DM, Jeker R, Hess C, Recher M.

J Allergy Clin Immunol. 2017 Mar;139(3):1043-1046.e5. doi: 10.1016/j.jaci.2016.08.042. Epub 2016 Nov 28. No abstract available.

PMID:
27908448
16.

SAKK 24/09: safety and tolerability of bevacizumab plus paclitaxel vs. bevacizumab plus metronomic cyclophosphamide and capecitabine as first-line therapy in patients with HER2-negative advanced stage breast cancer - a multicenter, randomized phase III trial.

Rochlitz C, Bigler M, von Moos R, Bernhard J, Matter-Walstra K, Wicki A, Zaman K, Anchisi S, Küng M, Na KJ, Bärtschi D, Borner M, Rordorf T, Rauch D, Müller A, Ruhstaller T, Vetter M, Trojan A, Hasler-Strub U, Cathomas R, Winterhalder R; Swiss Group for Clinical Cancer Research (SAKK).

BMC Cancer. 2016 Oct 10;16(1):780.

17.

Pericapillary basement membrane thickening in human skeletal muscles.

Baum O, Bigler M.

Am J Physiol Heart Circ Physiol. 2016 Sep 1;311(3):H654-66. doi: 10.1152/ajpheart.00048.2016. Epub 2016 Jul 1. Review.

18.

A systematic review and meta-analysis on the influence of biological implant surface coatings on periimplant bone formation.

Jenny G, Jauernik J, Bierbaum S, Bigler M, Grätz KW, Rücker M, Stadlinger B.

J Biomed Mater Res A. 2016 Nov;104(11):2898-910. doi: 10.1002/jbm.a.35805. Epub 2016 Jul 4. Review.

19.

Morphometry of skeletal muscle capillaries: the relationship between capillary ultrastructure and ageing in humans.

Bigler M, Koutsantonis D, Odriozola A, Halm S, Tschanz SA, Zakrzewicz A, Weichert A, Baum O.

Acta Physiol (Oxf). 2016 Oct;218(2):98-111. doi: 10.1111/apha.12709. Epub 2016 Jun 16.

PMID:
27174490
20.

Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels.

Bigler MB, Egli SB, Hysek CM, Hoenger G, Schmied L, Baldin FS, Marquardsen FA, Recher M, Liechti ME, Hess C, Berger CT.

PLoS One. 2015 Dec 23;10(12):e0145635. doi: 10.1371/journal.pone.0145635. eCollection 2015.

21.

Risk factors for pneumocystis pneumonia in giant cell arteritis: a single-centre cohort study.

Berger CT, Greiff V, John S, Koenig KF, Bigler MB, Recher M, Hess C, Daikeler T.

Clin Exp Rheumatol. 2015 Mar-Apr;33(2 Suppl 89):S-122-5. Epub 2015 May 26.

PMID:
26016762
22.

OrthoInspector 2.0: Software and database updates.

Linard B, Allot A, Schneider R, Morel C, Ripp R, Bigler M, Thompson JD, Poch O, Lecompte O.

Bioinformatics. 2015 Feb 1;31(3):447-8. doi: 10.1093/bioinformatics/btu642. Epub 2014 Oct 1.

23.

Continuous flow analysis method for determination of dissolved reactive phosphorus in ice cores.

Kjær HA, Vallelonga P, Svensson A, Kristensen ME, Tibuleac C, Bigler M.

Environ Sci Technol. 2013;47(21):12325-32. doi: 10.1021/es402274z. Epub 2013 Oct 15.

PMID:
24128116
24.

Continuous flow analysis of labile iron in ice-cores.

Hiscock WT, Fischer H, Bigler M, Gfeller G, Leuenberger D, Mini O.

Environ Sci Technol. 2013 May 7;47(9):4416-25. doi: 10.1021/es3047087. Epub 2013 Apr 17.

PMID:
23594184
25.

Optimization of high-resolution continuous flow analysis for transient climate signals in ice cores.

Bigler M, Svensson A, Kettner E, Vallelonga P, Nielsen ME, Steffensen JP.

Environ Sci Technol. 2011 May 15;45(10):4483-9. doi: 10.1021/es200118j. Epub 2011 Apr 19.

PMID:
21504155
26.

[Concerning confused persons. The burden should not become and abandonment].

Bigler M.

Krankenpfl Soins Infirm. 2010;103(6):12-4, 44-6, 64-6. French, German, Italian. No abstract available.

PMID:
20575242
27.

Absence of prosthesis-patient mismatch with the new generation of Edwards stented aortic bioprosthesis.

Wyss TR, Bigler M, Stalder M, Englberger L, Aymard T, Kadner A, Carrel TP.

Interact Cardiovasc Thorac Surg. 2010 Jun;10(6):884-7; discussion 887-8. doi: 10.1510/icvts.2009.224915. Epub 2010 Mar 16.

PMID:
20233807
28.

Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis.

Joyce-Shaikh B, Bigler ME, Chao CC, Murphy EE, Blumenschein WM, Adamopoulos IE, Heyworth PG, Antonenko S, Bowman EP, McClanahan TK, Phillips JH, Cua DJ.

J Exp Med. 2010 Mar 15;207(3):579-89. doi: 10.1084/jem.20090516. Epub 2010 Mar 8.

29.

Modulation of paired immunoglobulin-like type 2 receptor signaling alters the host response to Staphylococcus aureus-induced pneumonia.

Banerjee A, Stevenaert F, Pande K, Haghjoo E, Antonenko S, Gorman DM, Sathe M, McClanahan TK, Pierce R, Turner SP, Bigler ME, Phillips JH, Heyworth PG.

Infect Immun. 2010 Mar;78(3):1353-63. doi: 10.1128/IAI.00969-09. Epub 2010 Jan 11.

30.

Sulfate spikes in the deep layers of EPICA-Dome C ice core: evidence of glaciological artifacts.

Traversi R, Becagli S, Castellano E, Marino F, Rugi F, Severi M, de Angelis M, Fischer H, Hansson M, Stauffer B, Steffensen JP, Bigler M, Udisti R.

Environ Sci Technol. 2009 Dec 1;43(23):8737-43. doi: 10.1021/es901426y.

PMID:
19943640
31.

An improved continuous flow analysis system for high-resolution field measurements on ice cores.

Kaufmann PR, Federer U, Hutterli MA, Bigler M, Schüpbach S, Ruth U, Schmitt J, Stocker TF.

Environ Sci Technol. 2008 Nov 1;42(21):8044-50.

PMID:
19031900
32.

Proxies and measurement techniques for mineral dust in Antarctic ice cores.

Ruth U, Barbante C, Bigler M, Delmonte B, Fischer H, Gabrielli P, Gaspari V, Kaufmann P, Lambert F, Maggi V, Marino F, Petit JR, Udisti R, Wagenbach D, Wegner A, Wolff EW.

Environ Sci Technol. 2008 Aug 1;42(15):5675-81.

PMID:
18754492
33.

High-resolution Greenland ice core data show abrupt climate change happens in few years.

Steffensen JP, Andersen KK, Bigler M, Clausen HB, Dahl-Jensen D, Fischer H, Goto-Azuma K, Hansson M, Johnsen SJ, Jouzel J, Masson-Delmotte V, Popp T, Rasmussen SO, Röthlisberger R, Ruth U, Stauffer B, Siggaard-Andersen ML, Sveinbjörnsdóttir AE, Svensson A, White JW.

Science. 2008 Aug 1;321(5889):680-4. doi: 10.1126/science.1157707. Epub 2008 Jun 19.

34.

Dust-climate couplings over the past 800,000 years from the EPICA Dome C ice core.

Lambert F, Delmonte B, Petit JR, Bigler M, Kaufmann PR, Hutterli MA, Stocker TF, Ruth U, Steffensen JP, Maggi V.

Nature. 2008 Apr 3;452(7187):616-9. doi: 10.1038/nature06763.

PMID:
18385736
35.

Southern Ocean sea-ice extent, productivity and iron flux over the past eight glacial cycles.

Wolff EW, Fischer H, Fundel F, Ruth U, Twarloh B, Littot GC, Mulvaney R, Röthlisberger R, de Angelis M, Boutron CF, Hansson M, Jonsell U, Hutterli MA, Lambert F, Kaufmann P, Stauffer B, Stocker TF, Steffensen JP, Bigler M, Siggaard-Andersen ML, Udisti R, Becagli S, Castellano E, Severi M, Wagenbach D, Barbante C, Gabrielli P, Gaspari V.

Nature. 2006 Mar 23;440(7083):491-6. Erratum in: Nature. 2007 Oct 11;449(7163):748.

PMID:
16554810
36.

The CD200 receptor is a novel and potent regulator of murine and human mast cell function.

Cherwinski HM, Murphy CA, Joyce BL, Bigler ME, Song YS, Zurawski SM, Moshrefi MM, Gorman DM, Miller KL, Zhang S, Sedgwick JD, Phillips JH.

J Immunol. 2005 Feb 1;174(3):1348-56.

37.

High-resolution record of Northern Hemisphere climate extending into the last interglacial period.

Andersen KK, Azuma N, Barnola JM, Bigler M, Biscaye P, Caillon N, Chappellaz J, Clausen HB, Dahl-Jensen D, Fischer H, Flückiger J, Fritzsche D, Fujii Y, Goto-Azuma K, Grønvold K, Gundestrup NS, Hansson M, Huber C, Hvidberg CS, Johnsen SJ, Jonsell U, Jouzel J, Kipfstuhl S, Landais A, Leuenberger M, Lorrain R, Masson-Delmotte V, Miller H, Motoyama H, Narita H, Popp T, Rasmussen SO, Raynaud D, Rothlisberger R, Ruth U, Samyn D, Schwander J, Shoji H, Siggard-Andersen ML, Steffensen JP, Stocker T, Sveinbjörnsdóttir AE, Svensson A, Takata M, Tison JL, Thorsteinsson T, Watanabe O, Wilhelms F, White JW; North Greenland Ice Core Project members.

Nature. 2004 Sep 9;431(7005):147-51.

PMID:
15356621
38.

Eight glacial cycles from an Antarctic ice core.

Augustin L, Barbante C, Barnes PR, Barnola JM, Bigler M, Castellano E, Cattani O, Chappellaz J, Dahl-Jensen D, Delmonte B, Dreyfus G, Durand G, Falourd S, Fischer H, Flückiger J, Hansson ME, Huybrechts P, Jugie G, Johnsen SJ, Jouzel J, Kaufmann P, Kipfstuhl J, Lambert F, Lipenkov VY, Littot GC, Longinelli A, Lorrain R, Maggi V, Masson-Delmotte V, Miller H, Mulvaney R, Oerlemans J, Oerter H, Orombelli G, Parrenin F, Peel DA, Petit JR, Raynaud D, Ritz C, Ruth U, Schwander J, Siegenthaler U, Souchez R, Stauffer B, Steffensen JP, Stenni B, Stocker TF, Tabacco IE, Udisti R, Van De Wal RS, Van Den Broeke M, Weiss J, Wilhelms F, Winther JG, Wolff EW, Zucchelli M; EPICA community members.

Nature. 2004 Jun 10;429(6992):623-8.

PMID:
15190344
39.

Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.

Wright GJ, Cherwinski H, Foster-Cuevas M, Brooke G, Puklavec MJ, Bigler M, Song Y, Jenmalm M, Gorman D, McClanahan T, Liu MR, Brown MH, Sedgwick JD, Phillips JH, Barclay AN.

J Immunol. 2003 Sep 15;171(6):3034-46.

40.

IL-10 transgenic mice present a defect in T cell development reminiscent of SCID patients.

Rouleau M, Cottrez F, Bigler M, Antonenko S, Carballido JM, Zlotnik A, Roncarolo MG, Groux H.

J Immunol. 1999 Aug 1;163(3):1420-7.

41.

High spontaneous IL-10 production in unrelated bone marrow transplant recipients is associated with fewer transplant-related complications and early deaths.

Baker KS, Roncarolo MG, Peters C, Bigler M, DeFor T, Blazar BR.

Bone Marrow Transplant. 1999 Jun;23(11):1123-9.

42.

A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells.

Groux H, Cottrez F, Rouleau M, Mauze S, Antonenko S, Hurst S, McNeil T, Bigler M, Roncarolo MG, Coffman RL.

J Immunol. 1999 Feb 1;162(3):1723-9.

43.

Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells.

Groux H, Bigler M, de Vries JE, Roncarolo MG.

J Immunol. 1998 Apr 1;160(7):3188-93.

44.

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis.

Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, Roncarolo MG.

Nature. 1997 Oct 16;389(6652):737-42.

PMID:
9338786
45.

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.

Groux H, Bigler M, de Vries JE, Roncarolo MG.

J Exp Med. 1996 Jul 1;184(1):19-29.

46.

Immune functions of cord blood cells before and after transplantation.

Roncarolo MG, Bigler M, Martino S, Ciuti E, Tovo PA, Wagner J.

J Hematother. 1996 Apr;5(2):157-60. Review.

PMID:
8723794
47.
48.

HIV antibody testing and client retention in the therapeutic community. A preliminary report of Phoenix House.

Gonzalez I, Rosenthal MS, Bigler MO, Alper K, Geringer W.

J Subst Abuse Treat. 1994 Sep-Oct;11(5):481-8.

PMID:
7869470
49.

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

Bacchetta R, Bigler M, Touraine JL, Parkman R, Tovo PA, Abrams J, de Waal Malefyt R, de Vries JE, Roncarolo MG.

J Exp Med. 1994 Feb 1;179(2):493-502.

50.

Immune responses by cord blood cells.

Roncarolo MG, Bigler M, Ciuti E, Martino S, Tovo PA.

Blood Cells. 1994;20(2-3):573-85; discussion 585-6.

PMID:
7749123

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