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Items: 1 to 50 of 132

1.

IL-17-high asthma with features of a psoriasis immunophenotype.

Östling J, van Geest M, Schofield JPR, Jevnikar Z, Wilson S, Ward J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Horváth I, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, Auffray C, Sousa AR, Guo Y, Adcock IM, Howarth P, Chung KF, Bigler J, Sterk PJ, Skipp PJ, Djukanović R, Vaarala O; U-BIOPRED Study Group.

J Allergy Clin Immunol. 2019 Nov;144(5):1198-1213. doi: 10.1016/j.jaci.2019.03.027. Epub 2019 Apr 15.

PMID:
30998987
2.

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.

Werth VP, Fiorentino D, Sullivan BA, Boedigheimer MJ, Chiu K, Wang C, Arnold GE, Damore MA, Bigler J, Welcher AA, Russell CB, Martin DA, Chung JB.

Arthritis Rheumatol. 2017 May;69(5):1028-1034. doi: 10.1002/art.40052. Epub 2017 Mar 31.

3.

A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U-BIOPRED Cohorts.

Bigler J, Boedigheimer M, Schofield JPR, Skipp PJ, Corfield J, Rowe A, Sousa AR, Timour M, Twehues L, Hu X, Roberts G, Welcher AA, Yu W, Lefaudeux D, Meulder B, Auffray C, Chung KF, Adcock IM, Sterk PJ, Djukanović R; U-BIOPRED Study Group ‖.

Am J Respir Crit Care Med. 2017 May 15;195(10):1311-1320. doi: 10.1164/rccm.201604-0866OC.

4.

Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.

Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD.

Genom Data. 2015 Sep 1;6:154-8. doi: 10.1016/j.gdata.2015.08.029. eCollection 2015 Dec.

5.

Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

Maxwell JR, Zhang Y, Brown WA, Smith CL, Byrne FR, Fiorino M, Stevens E, Bigler J, Davis JA, Rottman JB, Budelsky AL, Symons A, Towne JE.

Immunity. 2015 Oct 20;43(4):739-50. doi: 10.1016/j.immuni.2015.08.019. Epub 2015 Sep 29.

6.

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK).

Heaney LG, Djukanovic R, Woodcock A, Walker S, Matthews JG, Pavord ID, Bradding P, Niven R, Brightling CE, Chaudhuri R, Arron JR, Choy DF, Cowan D, Mansur A, Menzies-Gow A, Adcock I, Chung KF, Corrigan C, Coyle P, Harrison T, Johnston S, Howarth P, Lordan J, Sabroe I, Bigler J, Smith D, Catley M, May R, Pierre L, Stevenson C, Crater G, Keane F, Costello RW, Hudson V, Supple D, Hardman T.

Thorax. 2016 Feb;71(2):187-9. doi: 10.1136/thoraxjnl-2015-207326. Epub 2015 Jul 23. Review.

7.

Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.

Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD.

BMC Med Genet. 2015 Mar 24;16:18. doi: 10.1186/s12881-015-0161-6.

8.

Effects of an anti-TSLP antibody on allergen-induced asthmatic responses.

Gauvreau GM, O'Byrne PM, Boulet LP, Wang Y, Cockcroft D, Bigler J, FitzGerald JM, Boedigheimer M, Davis BE, Dias C, Gorski KS, Smith L, Bautista E, Comeau MR, Leigh R, Parnes JR.

N Engl J Med. 2014 May 29;370(22):2102-10. doi: 10.1056/NEJMoa1402895. Epub 2014 May 20.

9.

Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.

Russell CB, Rand H, Bigler J, Kerkof K, Timour M, Bautista E, Krueger JG, Salinger DH, Welcher AA, Martin DA.

J Immunol. 2014 Apr 15;192(8):3828-36. doi: 10.4049/jimmunol.1301737. Epub 2014 Mar 19.

10.

Trends in blood mercury concentrations and fish consumption among U.S. women of reproductive age, NHANES, 1999-2010.

Birch RJ, Bigler J, Rogers JW, Zhuang Y, Clickner RP.

Environ Res. 2014 Aug;133:431-8. doi: 10.1016/j.envres.2014.02.001. Epub 2014 Mar 3.

PMID:
24602558
11.

Butyrophilin-like 2 modulates B7 costimulation to induce Foxp3 expression and regulatory T cell development in mature T cells.

Swanson RM, Gavin MA, Escobar SS, Rottman JB, Lipsky BP, Dube S, Li L, Bigler J, Wolfson M, Arnett HA, Viney JL.

J Immunol. 2013 Mar 1;190(5):2027-35. doi: 10.4049/jimmunol.1201760. Epub 2013 Jan 28.

12.

Cross-study homogeneity of psoriasis gene expression in skin across a large expression range.

Bigler J, Rand HA, Kerkof K, Timour M, Russell CB.

PLoS One. 2013;8(1):e52242. doi: 10.1371/journal.pone.0052242. Epub 2013 Jan 4.

13.

UGT1A6 and UGT2B15 polymorphisms and acetaminophen conjugation in response to a randomized, controlled diet of select fruits and vegetables.

Navarro SL, Chen Y, Li L, Li SS, Chang JL, Schwarz Y, King IB, Potter JD, Bigler J, Lampe JW.

Drug Metab Dispos. 2011 Sep;39(9):1650-7. doi: 10.1124/dmd.111.039149. Epub 2011 Jun 10.

14.

Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases.

Navarro SL, Saracino MR, Makar KW, Thomas SS, Li L, Zheng Y, Levy L, Schwarz Y, Bigler J, Potter JD, Lampe JW.

J Nutrigenet Nutrigenomics. 2011;4(2):110-8. doi: 10.1159/000327782. Epub 2011 May 28.

15.

DNA damage and repair: fruit and vegetable effects in a feeding trial.

Chang JL, Chen G, Ulrich CM, Bigler J, King IB, Schwarz Y, Li S, Li L, Potter JD, Lampe JW.

Nutr Cancer. 2010;62(3):329-35. doi: 10.1080/01635580903407106.

16.

Comparison of the evaluations of a case-based reasoning decision support tool by specialist expert reviewers with those of end users.

Walsh P, Doyle D, McQuillen KK, Bigler J, Thompson C, Lin E, Cunningham P.

West J Emerg Med. 2008 May;9(2):74-80.

17.

Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism.

Saracino MR, Bigler J, Schwarz Y, Chang JL, Li S, Li L, White E, Potter JD, Lampe JW.

J Nutr. 2009 Mar;139(3):555-60. doi: 10.3945/jn.108.097279. Epub 2009 Jan 13.

18.

C-reactive protein genotypes and haplotypes, polymorphisms in NSAID-metabolizing enzymes, and risk of colorectal polyps.

Poole EM, Bigler J, Whitton J, Sibert JG, Potter JD, Ulrich CM.

Pharmacogenet Genomics. 2009 Feb;19(2):113-20. doi: 10.1097/FPC.0b013e32831bd976.

19.

Assisted suicide and euthanasia should not be practiced in palliative care units.

Pereira J, Anwar D, Pralong G, Pralong J, Mazzocato C, Bigler JM.

J Palliat Med. 2008 Oct;11(8):1074-6. doi: 10.1089/jpm.2008.0093. No abstract available.

PMID:
18980445
20.

Serum beta-glucuronidase activity in response to fruit and vegetable supplementation: a controlled feeding study.

Maruti SS, Chang JL, Prunty JA, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW.

Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1808-12. doi: 10.1158/1055-9965.EPI-07-2660.

21.

Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors.

Campbell PT, Curtin K, Ulrich CM, Samowitz WS, Bigler J, Velicer CM, Caan B, Potter JD, Slattery ML.

Gut. 2009 May;58(5):661-7. doi: 10.1136/gut.2007.144220. Epub 2008 Jun 3.

22.

DNA methyltransferase and alcohol dehydrogenase: gene-nutrient interactions in relation to risk of colorectal polyps.

Jung AY, Poole EM, Bigler J, Whitton J, Potter JD, Ulrich CM.

Cancer Epidemiol Biomarkers Prev. 2008 Feb;17(2):330-8. doi: 10.1158/1055-9965.EPI-07-2608.

23.

UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.

Chen Y, Kuehl GE, Bigler J, Rimorin CF, Schwarz Y, Shen DD, Lampe JW.

Pharmacogenet Genomics. 2007 Aug;17(8):571-9.

PMID:
17622933
24.

Polymorphisms predicted to alter function in prostaglandin E2 synthase and prostaglandin E2 receptors.

Bigler J, Sibert JG, Poole EM, Carlson CS, Potter JD, Ulrich CM.

Pharmacogenet Genomics. 2007 Mar;17(3):221-7.

PMID:
17460551
25.

Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.

Curtin K, Slattery ML, Ulrich CM, Bigler J, Levin TR, Wolff RK, Albertsen H, Potter JD, Samowitz WS.

Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21.

26.

UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial.

Chang JL, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW.

J Nutr. 2007 Apr;137(4):890-7.

PMID:
17374650
27.

Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival.

Curtin K, Ulrich CM, Samowitz WS, Bigler J, Caan B, Potter JD, Slattery ML.

Int J Cancer. 2007 May 15;120(10):2226-32.

28.

Genetic variability in prostaglandin synthesis, fish intake and risk of colorectal polyps.

Poole EM, Bigler J, Whitton J, Sibert JG, Kulmacz RJ, Potter JD, Ulrich CM.

Carcinogenesis. 2007 Jun;28(6):1259-63. Epub 2007 Feb 2.

PMID:
17277229
29.

Genetic tools to tailor cancer prevention by NSAIDs.

Ulrich CM, Bigler J, Potter JD.

Discov Med. 2006 Apr;6(32):71-4.

30.

Ascending the learning curve--MSI testing experience of a six-laboratory consortium.

Lindor NM, Smalley R, Barker M, Bigler J, Krumroy LM, Lum-Jones A, Plummer SJ, Selander T, Thomas S, Youash M, Seminara D, Casey G, Bapat B, Thibodeau SN.

Cancer Biomark. 2006;2(1-2):5-9.

PMID:
17192055
31.

Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.

Goode EL, Potter JD, Bamlet WR, Rider DN, Bigler J.

Carcinogenesis. 2007 Feb;28(2):328-41. Epub 2006 Aug 21.

PMID:
16926176
32.
33.

Risk of microsatellite-unstable colorectal cancer is associated jointly with smoking and nonsteroidal anti-inflammatory drug use.

Chia VM, Newcomb PA, Bigler J, Morimoto LM, Thibodeau SN, Potter JD.

Cancer Res. 2006 Jul 1;66(13):6877-83.

34.

Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.

Thomas SS, Li SS, Lampe JW, Potter JD, Bigler J.

Hum Mutat. 2006 Jul;27(7):717.

PMID:
16786511
35.

Mismatch repair polymorphisms and colorectal polyps: hMLH1-93G>A variant modifies risk associated with smoking.

Yu JH, Bigler J, Whitton J, Potter JD, Ulrich CM.

Am J Gastroenterol. 2006 Jun;101(6):1313-9.

PMID:
16771955
36.

Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.

Poole EM, Bigler J, Whitton J, Sibert JG, Potter JD, Ulrich CM.

Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):502-8.

37.

Methylenetetrahydrofolate reductase and thymidylate synthase genotypes modify oral mucositis severity following hematopoietic stem cell transplantation.

Robien K, Schubert MM, Chay T, Bigler J, Storb R, Yasui Y, Potter JD, Ulrich CM.

Bone Marrow Transplant. 2006 Apr;37(8):799-800. No abstract available.

PMID:
16501586
38.

Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics.

Ulrich CM, Bigler J, Potter JD.

Nat Rev Cancer. 2006 Feb;6(2):130-40. Review.

PMID:
16491072
39.

Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer.

Ulrich CM, Curtin K, Potter JD, Bigler J, Caan B, Slattery ML.

Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2509-16.

40.

DNA repair polymorphisms and risk of colorectal adenomatous or hyperplastic polyps.

Bigler J, Ulrich CM, Kawashima T, Whitton J, Potter JD.

Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2501-8.

41.

Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.

Kuehl GE, Bigler J, Potter JD, Lampe JW.

Drug Metab Dispos. 2006 Feb;34(2):199-202. Epub 2005 Oct 28.

PMID:
16258079
42.

MTHFR variants reduce the risk of G:C->A:T transition mutations within the p53 tumor suppressor gene in colon tumors.

Ulrich CM, Curtin K, Samowitz W, Bigler J, Potter JD, Caan B, Slattery ML.

J Nutr. 2005 Oct;135(10):2462-7.

PMID:
16177213
43.

Thromboxane synthase (TBXAS1) polymorphisms in African-American and Caucasian populations: evidence for selective pressure.

Ulrich CM, Carlson CS, Sibert J, Poole EM, Yu JH, Wang LH, Sparks R, Potter JD, Bigler J.

Hum Mutat. 2005 Oct;26(4):394-5.

PMID:
16134166
44.

Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: personal and lifestyle factors (United States).

Morimoto LM, Newcomb PA, White E, Bigler J, Potter JD.

Cancer Causes Control. 2005 Oct;16(8):917-27.

PMID:
16132801
45.

FDR-controlling testing procedures and sample size determination for microarrays.

Li SS, Bigler J, Lampe JW, Potter JD, Feng Z.

Stat Med. 2005 Aug 15;24(15):2267-80.

PMID:
15977294
46.

Accuracy and reproducibility of short tandem repeat assays.

Bigler J.

Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1581; author reply 1581-2. No abstract available.

47.

Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: genetic factors.

Morimoto LM, Newcomb PA, White E, Bigler J, Potter JD.

Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1394-401.

48.

Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk.

Robien K, Curtin K, Ulrich CM, Bigler J, Samowitz W, Caan B, Potter JD, Slattery ML.

Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1350-2. No abstract available.

49.

Insulin-like growth factor polymorphisms and colorectal cancer risk.

Morimoto LM, Newcomb PA, White E, Bigler J, Potter JD.

Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1204-11.

50.

Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans.

Peterson S, Bigler J, Horner NK, Potter JD, Lampe JW.

J Nutr. 2005 May;135(5):1051-5.

PMID:
15867280

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