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Items: 1 to 50 of 152

1.

Kinetochore-associated Stu2 promotes chromosome biorientation in vivo.

Miller MP, Evans RK, Zelter A, Geyer EA, MacCoss MJ, Rice LM, Davis TN, Asbury CL, Biggins S.

PLoS Genet. 2019 Oct 4;15(10):e1008423. doi: 10.1371/journal.pgen.1008423. [Epub ahead of print]

2.

Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores.

Koch LB, Opoku KN, Deng Y, Barber A, Littleton AJ, London N, Biggins S, Asbury CL.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17355-17360. doi: 10.1073/pnas.1901653116. Epub 2019 Aug 12.

PMID:
31405987
3.

Copper Deficiency in Liver Diseases: A Case Series and Pathophysiological Considerations.

Yu L, Liou IW, Biggins SW, Yeh M, Jalikis F, Chan LN, Burkhead J.

Hepatol Commun. 2019 Jun 26;3(8):1159-1165. doi: 10.1002/hep4.1393. eCollection 2019 Aug.

4.

New Evidence Supporting Increased Use of Split Liver Transplantation.

Perkins JD, Dick AA, Healey PJ, Montenovo MI, Biggins SW, Sibulesky L, Reyes JD.

Transplantation. 2019 Jun 27. doi: 10.1097/TP.0000000000002853. [Epub ahead of print]

PMID:
31335771
5.

The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest.

Leontiou I, London N, May KM, Ma Y, Grzesiak L, Medina-Pritchard B, Amin P, Jeyaprakash AA, Biggins S, Hardwick KG.

Curr Biol. 2019 Jul 22;29(14):2407-2414.e7. doi: 10.1016/j.cub.2019.06.011. Epub 2019 Jun 27.

6.

Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.

Bajaj JS, OʼLeary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Biggins SW, Lai JC, Vargas HE, Maliakkal B, Fallon MB, Thuluvath PJ, Subramanian RM, Thacker LR, Reddy KR.

Am J Gastroenterol. 2019 Jul;114(7):1091-1100. doi: 10.14309/ajg.0000000000000280.

PMID:
31180922
7.

Listing practices and graft utilization of hepatitis C-positive deceased donors in liver and kidney transplant.

Kling CE, Perkins JD, Biggins SW, Johnson CK, Limaye AP, Sibulesky L.

Surgery. 2019 Jul;166(1):102-108. doi: 10.1016/j.surg.2019.03.015. Epub 2019 May 6.

PMID:
31072671
8.

Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.

Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR.

Aliment Pharmacol Ther. 2019 Jun;49(12):1518-1527. doi: 10.1111/apt.15265. Epub 2019 Apr 29.

PMID:
31032966
9.

Albumin in Cirrhosis: More Than a Colloid.

Paine CH, Biggins SW, Pichler RH.

Curr Treat Options Gastroenterol. 2019 Jun;17(2):231-243. doi: 10.1007/s11938-019-00227-4. Review.

PMID:
30968341
10.

Thromboelastography Parameters Are Associated with Cirrhosis Severity.

Kohli R, Shingina A, New S, Chaturvedi S, Benson A, Biggins SW, Bambha K.

Dig Dis Sci. 2019 Sep;64(9):2661-2670. doi: 10.1007/s10620-019-05597-4. Epub 2019 Mar 26.

PMID:
30915655
11.

Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.

Wong F, Reddy KR, O'Leary JG, Tandon P, Biggins SW, Garcia-Tsao G, Maliakkal BJ, Lai JC, Fallon MB, Vargas HE, Subramanian R, Thuluvath PJ, Kamath PS, Thacker L, Bajaj JS.

Liver Transpl. 2019 Jun;25(6):870-880. doi: 10.1002/lt.25454. Epub 2019 Apr 25.

PMID:
30908855
12.

Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.

O'Leary JG, Bajaj JS, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Reddy KR.

Liver Transpl. 2019 Apr;25(4):571-579. doi: 10.1002/lt.25426. Epub 2019 Mar 24.

PMID:
30724010
13.

A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence After Liver Transplantation: The Recurrent Hepatocellular Carcinoma-Initial, Maximum, Last Classification.

Vutien P, Dodge J, Bambha KM, Nordstrom EM, Gralla J, Campbell K, Levek C, Nydam T, Fix O, Ioannou G, Biggins SW.

Liver Transpl. 2019 Apr;25(4):559-570. doi: 10.1002/lt.25422.

PMID:
30706653
14.

Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.

Bajaj JS, Tandon P, OʼLeary JG, Wong F, Biggins SW, Garcia-Tsao G, Kamath PS, Maliakkal B, Fallon MB, Lai JC, Thuluvath PJ, Vargas HE, Subramanian RM, Thacker LR, Reddy KR.

Am J Gastroenterol. 2019 Apr;114(4):599-606. doi: 10.14309/ajg.0000000000000044.

PMID:
30694868
15.

Reply.

Biggins SW, Dodge J, Bambha K.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):574-575. doi: 10.1016/j.cgh.2018.08.062. No abstract available.

PMID:
30678843
16.

Future Trends in Demand for Liver Transplant: Birth Cohort Effects Among Patients With NASH and HCC.

Shingina A, DeWitt PE, Dodge JL, Biggins SW, Gralla J, Sprague D, Bambha K.

Transplantation. 2019 Jan;103(1):140-148. doi: 10.1097/TP.0000000000002497.

PMID:
30451739
17.

Protecting kidneys in liver transplant patients: A pathway to preventive interventions.

Sibulesky L, Biggins SW, Pichler R.

World J Hepatol. 2018 Sep 27;10(9):637-638. doi: 10.4254/wjh.v10.i9.637.

18.

A Kinesin-5, Cin8, Recruits Protein Phosphatase 1 to Kinetochores and Regulates Chromosome Segregation.

Suzuki A, Gupta A, Long SK, Evans R, Badger BL, Salmon ED, Biggins S, Bloom K.

Curr Biol. 2018 Sep 10;28(17):2697-2704.e3. doi: 10.1016/j.cub.2018.08.038. Epub 2018 Aug 30.

19.

An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast.

Lang J, Barber A, Biggins S.

Elife. 2018 Aug 17;7. pii: e37819. doi: 10.7554/eLife.37819.

20.

Design principles of a microtubule polymerase.

Geyer EA, Miller MP, Brautigam CA, Biggins S, Rice LM.

Elife. 2018 Jun 13;7. pii: e34574. doi: 10.7554/eLife.34574.

21.

The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.

Bajaj JS, Tandon P, OʼLeary JG, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Thuluvath P, Vargas HE, Subramanian RM, Thacker LR, Reddy RK.

Am J Gastroenterol. 2018 Sep;113(9):1339. doi: 10.1038/s41395-018-0119-3. Epub 2018 Jun 8.

PMID:
29880972
22.

Purification of kinetochores from the budding yeast Saccharomyces cerevisiae.

Gupta A, Evans RK, Koch LB, Littleton AJ, Biggins S.

Methods Cell Biol. 2018;144:349-370. doi: 10.1016/bs.mcb.2018.03.023. Epub 2018 May 11.

23.

Calcineurin Inhibitor and Nonsteroidal Anti-inflammatory Drug Interaction: Implications of Changes in Renal Function Associated With Concurrent Use.

Delzer LM, Golightly LK, Kiser TH, Biggins SW, Lewis VJ, Kim II.

J Clin Pharmacol. 2018 Nov;58(11):1443-1451. doi: 10.1002/jcph.1264. Epub 2018 May 25.

PMID:
29799625
24.

Neutrophil-to-Lymphocyte Ratio Associates Independently With Mortality in Hospitalized Patients With Cirrhosis.

Rice J, Dodge JL, Bambha KM, Bajaj JS, Reddy KR, Gralla J, Ganapathy D, Mitrani R, Reuter B, Palecki J, Acharya C, Shaw J, Burton JR, Biggins SW.

Clin Gastroenterol Hepatol. 2018 Nov;16(11):1786-1791.e1. doi: 10.1016/j.cgh.2018.04.045. Epub 2018 Apr 26.

PMID:
29705264
25.

Trends in liver transplantation for hepatitis C in a country with reduced access to direct-acting antiviral agents.

Dirchwolf M, Marciano S, Giunta DH, Posadas-Martínez ML, Biggins SW, Ruf AE.

Clin Transplant. 2018 Apr;32(4):e13230. doi: 10.1111/ctr.13230. Epub 2018 Mar 23.

PMID:
29485711
26.

New paradigms for organ allocation and distribution in liver transplantation.

Kalra A, Biggins SW.

Curr Opin Gastroenterol. 2018 May;34(3):123-131. doi: 10.1097/MOG.0000000000000434. Review.

PMID:
29465430
27.

Assessment of the spectrum of hepatic encephalopathy: A multicenter study.

Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS.

Liver Transpl. 2018 May;24(5):587-594. doi: 10.1002/lt.25032.

28.

NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.

O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS.

Hepatology. 2018 Jun;67(6):2367-2374. doi: 10.1002/hep.29773. Epub 2018 Apr 19.

PMID:
29315693
29.

Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.

Bajaj JS, Reddy RK, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, OʼLeary JG.

Am J Gastroenterol. 2018 Apr;113(4):556-563. doi: 10.1038/ajg.2017.471. Epub 2017 Dec 19.

PMID:
29257141
30.

Stochastic Modeling Yields a Mechanistic Framework for Spindle Attachment Error Correction in Budding Yeast Mitosis.

Tubman ES, Biggins S, Odde DJ.

Cell Syst. 2017 Jun 28;4(6):645-650.e5. doi: 10.1016/j.cels.2017.05.003. Epub 2017 Jun 7.

31.

Acute Kidney Injury in Cirrhosis: Baseline Serum Creatinine Predicts Patient Outcomes.

Wong F, O'Leary JG, Reddy KR, Garcia-Tsao G, Fallon MB, Biggins SW, Subramanian RM, Thuluvath PJ, Kamath PS, Patton H, Maliakkal B, Tandon P, Vargas H, Thacker L, Bajaj JS.

Am J Gastroenterol. 2017 Jul;112(7):1103-1110. doi: 10.1038/ajg.2017.122. Epub 2017 Apr 25.

PMID:
28440305
32.

Gender-Specific Differences in Baseline, Peak, and Delta Serum Creatinine: The NACSELD Experience.

O'Leary JG, Wong F, Reddy KR, Garcia-Tsao G, Kamath PS, Biggins SW, Fallon MB, Subramanian RM, Maliakkal B, Thacker L, Bajaj JS.

Dig Dis Sci. 2017 Mar;62(3):768-776. doi: 10.1007/s10620-016-4416-7. Epub 2016 Dec 26.

PMID:
28025746
33.

Neutrophil-to-lymphocyte ratio correlates with proinflammatory neutrophils and predicts death in low model for end-stage liver disease patients with cirrhosis.

Kalra A, Wedd JP, Bambha KM, Gralla J, Golden-Mason L, Collins C, Rosen HR, Biggins SW.

Liver Transpl. 2017 Feb;23(2):155-165. doi: 10.1002/lt.24702.

34.

Corrigendum: Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit.

Akiyoshi B, Nelson CR, Ranish JA, Biggins S.

Genes Dev. 2016 Oct 15;30(20):2339. No abstract available.

35.

Histone H4 Facilitates the Proteolysis of the Budding Yeast CENP-ACse4 Centromeric Histone Variant.

Deyter GM, Hildebrand EM, Barber AD, Biggins S.

Genetics. 2017 Jan;205(1):113-124. doi: 10.1534/genetics.116.194027. Epub 2016 Oct 28.

36.

A Karnofsky performance status-based score predicts death after hospital discharge in patients with cirrhosis.

Tandon P, Reddy KR, O'Leary JG, Garcia-Tsao G, Abraldes JG, Wong F, Biggins SW, Maliakkal B, Fallon MB, Subramanian RM, Thuluvath P, Kamath PS, Thacker LR, Bajaj JS; North American Consortium for the Study of End-Stage Liver Disease.

Hepatology. 2017 Jan;65(1):217-224. doi: 10.1002/hep.28900. Epub 2016 Nov 29.

PMID:
27775842
37.

Revising metrics for aggressiveness assessment in liver transplantation centers.

Ruf AE, Dirchwolf M, Biggins SW, Villamil FG.

J Hepatol. 2016 Nov;65(5):1066-1067. doi: 10.1016/j.jhep.2016.06.033. Epub 2016 Jul 28. No abstract available.

PMID:
27476766
38.

Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.

Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Maliakkal B, Biggins SW, Thuluvath PJ, Fallon MB, Subramanian RM, Vargas HE, Lai J, Thacker LR, Reddy KR.

Clin Gastroenterol Hepatol. 2017 Apr;15(4):565-574.e4. doi: 10.1016/j.cgh.2016.09.157. Epub 2016 Oct 5.

PMID:
27720916
39.

Predicting renal recovery after liver transplant with severe pretransplant subacute kidney injury: The impact of warm ischemia time.

Laskey HL, Schomaker N, Hung KW, Asrani SK, Jennings L, Nydam TL, Gralla J, Wiseman A, Rosen HR, Biggins SW.

Liver Transpl. 2016 Aug;22(8):1085-91. doi: 10.1002/lt.24488. Epub 2016 Jul 12.

40.

A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments.

Miller MP, Asbury CL, Biggins S.

Cell. 2016 Jun 2;165(6):1428-1439. doi: 10.1016/j.cell.2016.04.030. Epub 2016 May 5.

41.

Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects.

Hildebrand EM, Biggins S.

PLoS Genet. 2016 Mar 16;12(3):e1005930. doi: 10.1371/journal.pgen.1005930. eCollection 2016 Mar.

42.

Changing prioritization for transplantation: MELD-Na, hepatocellular carcinoma exceptions, and more.

Kalra A, Wedd JP, Biggins SW.

Curr Opin Organ Transplant. 2016 Apr;21(2):120-6. doi: 10.1097/MOT.0000000000000281. Review.

PMID:
26825358
43.

The 3-month readmission rate remains unacceptably high in a large North American cohort of patients with cirrhosis.

Bajaj JS, Reddy KR, Tandon P, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Biggins SW, Thuluvath PJ, Fallon MB, Subramanian RM, Vargas H, Thacker LR, O'Leary JG; North American Consortium for the Study of End-Stage Liver Disease.

Hepatology. 2016 Jul;64(1):200-8. doi: 10.1002/hep.28414. Epub 2016 Feb 19.

44.

Consensus Interferon for Recurrent Hepatitis C Infection in Nonresponders to Peginterferon and Ribavirin After Liver Transplant.

Nordstrom EM, Biggins SW, Gralla J, Rosen HR, Everson GT, Burton JR Jr.

Exp Clin Transplant. 2015 Dec;13(6):543-9.

45.

Impact of body mass index on posttransplant outcomes reexamined.

Bambha KM, Dodge JL, Gralla J, Biggins SW.

Liver Transpl. 2016 Feb;22(2):261-2. doi: 10.1002/lt.24363. No abstract available.

46.

Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure.

Rosen HR, Biggins SW, Niki T, Gralla J, Hillman H, Hirashima M, Schilsky M, Lee WM; Acute Liver Failure Study Group.

Clin Gastroenterol Hepatol. 2016 Apr;14(4):606-612.e3. doi: 10.1016/j.cgh.2015.09.040. Epub 2015 Oct 20.

PMID:
26499927
47.

Hepatocellular carcinoma in patients listed for liver transplantation: Current and future allocation policy and management strategies for the individual patient.

Wedd JP, Nordstrom E, Nydam T, Durham J, Zimmerman M, Johnson T, Thomas Purcell W, Biggins SW.

Liver Transpl. 2015 Dec;21(12):1543-52. doi: 10.1002/lt.24356. Review.

48.

Under Tension: Kinetochores and Basic Research.

Biggins S.

Genetics. 2015 Jul;200(3):681-2. doi: 10.1534/genetics.115.178467.

49.

Low, rather than high, body mass index confers increased risk for post-liver transplant death and graft loss: Risk modulated by model for end-stage liver disease.

Bambha KM, Dodge JL, Gralla J, Sprague D, Biggins SW.

Liver Transpl. 2015 Oct;21(10):1286-94. doi: 10.1002/lt.24188.

50.

The corrected donor age for hepatitis C virus-infected liver transplant recipients.

Dirchwolf M, Dodge JL, Gralla J, Bambha KM, Nydam T, Hung KW, Rosen HR, Feng S, Terrault NA, Biggins SW.

Liver Transpl. 2015 Aug;21(8):1022-30. doi: 10.1002/lt.24194.

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