Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 102

1.

Chernobyl cleanup workers from Estonia: cohort description and related epidemiological research.

Rahu K, Rahu M, Tekkel M, Veidebaum T, Hakulinen T, Auvinen A, Bigbee WL, Hartshorne MF, Inskip PD, Boice JD Jr.

J Radiol Prot. 2015 Dec;35(4):R35-45. doi: 10.1088/0952-4746/35/4/R35. Epub 2015 Oct 29. Review.

PMID:
26512763
2.

Validation of a blood protein signature for non-small cell lung cancer.

Mehan MR, Williams SA, Siegfried JM, Bigbee WL, Weissfeld JL, Wilson DO, Pass HI, Rom WN, Muley T, Meister M, Franklin W, Miller YE, Brody EN, Ostroff RM.

Clin Proteomics. 2014 Aug 1;11(1):32. doi: 10.1186/1559-0275-11-32. eCollection 2014.

3.

Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma.

Zaidi AH, Gopalakrishnan V, Kasi PM, Zeng X, Malhotra U, Balasubramanian J, Visweswaran S, Sun M, Flint MS, Davison JM, Hood BL, Conrads TP, Bergman JJ, Bigbee WL, Jobe BA.

Cancer. 2014 Dec 15;120(24):3902-13. doi: 10.1002/cncr.28963. Epub 2014 Aug 5.

4.

Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration.

McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA.

BMC Med. 2013 Oct 17;11:220. doi: 10.1186/1741-7015-11-220.

5.

Criteria for the use of omics-based predictors in clinical trials.

McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA.

Nature. 2013 Oct 17;502(7471):317-20. doi: 10.1038/nature12564.

6.

Proteomic Analysis of Matched Formalin-Fixed, Paraffin-Embedded Specimens in Patients with Advanced Serous Ovarian Carcinoma.

Smith AL, Sun M, Bhargava R, Stewart NA, Flint MS, Bigbee WL, Krivak TC, Strange MA, Cooper KL, Zorn KK.

Proteomes. 2013 Oct 17;1(3):240-253. doi: 10.3390/proteomes1030240.

7.

Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study.

Seymour CW, Yende S, Scott MJ, Pribis J, Mohney RP, Bell LN, Chen YF, Zuckerbraun BS, Bigbee WL, Yealy DM, Weissfeld L, Kellum JA, Angus DC.

Intensive Care Med. 2013 Aug;39(8):1423-34. doi: 10.1007/s00134-013-2935-7. Epub 2013 May 15.

8.

Automated lobe-based airway labeling.

Gu S, Wang Z, Siegfried JM, Wilson D, Bigbee WL, Pu J.

Int J Biomed Imaging. 2012;2012:382806. doi: 10.1155/2012/382806. Epub 2012 Oct 9.

9.

Three-dimensional airway tree architecture and pulmonary function.

Pu J, Leader JK, Meng X, Whiting B, Wilson D, Sciurba FC, Reilly JJ, Bigbee WL, Siegfried J, Gur D.

Acad Radiol. 2012 Nov;19(11):1395-401. doi: 10.1016/j.acra.2012.06.007. Epub 2012 Aug 11.

10.

Identification of pulmonary fissures using a piecewise plane fitting algorithm.

Gu S, Wilson D, Wang Z, Bigbee WL, Siegfried J, Gur D, Pu J.

Comput Med Imaging Graph. 2012 Oct;36(7):560-71. doi: 10.1016/j.compmedimag.2012.06.001. Epub 2012 Jun 29.

11.

A multiplexed serum biomarker immunoassay panel discriminates clinical lung cancer patients from high-risk individuals found to be cancer-free by CT screening.

Bigbee WL, Gopalakrishnan V, Weissfeld JL, Wilson DO, Dacic S, Lokshin AE, Siegfried JM.

J Thorac Oncol. 2012 Apr;7(4):698-708. doi: 10.1097/JTO.0b013e31824ab6b0.

12.

Serum biomarker profiles as diagnostic tools in lung cancer.

Nolen BM, Langmead CJ, Choi S, Lomakin A, Marrangoni A, Bigbee WL, Weissfeld JL, Wilson DO, Dacic S, Siegfried JM, Lokshin AE.

Cancer Biomark. 2011-2012;10(1):3-12. doi: 10.3233/CBM-2012-0229.

13.

A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface.

Li X, LeBlanc J, Truong A, Vuthoori R, Chen SS, Lustgarten JL, Roth B, Allard J, Ippoliti A, Presley LL, Borneman J, Bigbee WL, Gopalakrishnan V, Graeber TG, Elashoff D, Braun J, Goodglick L.

PLoS One. 2011;6(11):e26542. doi: 10.1371/journal.pone.0026542. Epub 2011 Nov 21.

14.

Relative quantitation of proteins in expressed prostatic secretion with a stable isotope labeled secretome standard.

Zhao T, Zeng X, Bateman NW, Sun M, Teng PN, Bigbee WL, Dhir R, Nelson JB, Conrads TP, Hood BL.

J Proteome Res. 2012 Feb 3;11(2):1089-99. doi: 10.1021/pr200829f. Epub 2011 Dec 1.

PMID:
22077639
15.

Transfer learning of classification rules for biomarker discovery and verification from molecular profiling studies.

Ganchev P, Malehorn D, Bigbee WL, Gopalakrishnan V.

J Biomed Inform. 2011 Dec;44 Suppl 1:S17-23. doi: 10.1016/j.jbi.2011.04.009. Epub 2011 May 6.

16.

Lung cancer serum biomarker discovery using label-free liquid chromatography-tandem mass spectrometry.

Zeng X, Hood BL, Zhao T, Conrads TP, Sun M, Gopalakrishnan V, Grover H, Day RS, Weissfeld JL, Wilson DO, Siegfried JM, Bigbee WL.

J Thorac Oncol. 2011 Apr;6(4):725-34. doi: 10.1097/JTO.0b013e31820c312e.

17.

Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.

Ostroff RM, Bigbee WL, Franklin W, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld JL, Williams S, Zichi D, Brody EN.

PLoS One. 2010 Dec 7;5(12):e15003. doi: 10.1371/journal.pone.0015003.

18.

Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry.

Zeng X, Hood BL, Sun M, Conrads TP, Day RS, Weissfeld JL, Siegfried JM, Bigbee WL.

J Proteome Res. 2010 Dec 3;9(12):6440-9. doi: 10.1021/pr100696n. Epub 2010 Oct 28.

19.

Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR.

Ostrow KL, Hoque MO, Loyo M, Brait M, Greenberg A, Siegfried JM, Grandis JR, Gaither Davis A, Bigbee WL, Rom W, Sidransky D.

Clin Cancer Res. 2010 Jul 1;16(13):3463-72. doi: 10.1158/1078-0432.CCR-09-3304. Epub 2010 Jun 30.

20.

Cigarette smoking during pregnancy: chromosome translocations and phenotypic susceptibility in mothers and newborns.

Bennett LM, Wang Y, Ramsey MJ, Harger GF, Bigbee WL, Tucker JD.

Mutat Res. 2010 Feb;696(1):81-8. doi: 10.1016/j.mrgentox.2009.12.015. Epub 2010 Jan 7.

21.

Serum proteomics using mass spectrometry.

Hood BL, Malehorn DE, Conrads TP, Bigbee WL.

Methods Mol Biol. 2009;520:107-28. doi: 10.1007/978-1-60327-811-9_8.

PMID:
19381950
22.

County mortality and cancer incidence in relation to living near two former nuclear materials processing facilities in Pennsylvania--an update.

Boice JD Jr, Bigbee WL, Mumma MT, Tarone RE, Blot WJ.

Health Phys. 2009 Feb;96(2):128-37. doi: 10.1097/01.HP.0000327664.79349.d4.

PMID:
19131734
23.

Cancer incidence in municipalities near two former nuclear materials processing facilities in Pennsylvania--an update.

Boice JD Jr, Bigbee WL, Mumma MT, Heath CW Jr, Blot WJ.

Health Phys. 2009 Feb;96(2):118-27. doi: 10.1097/01.HP.0000334548.64581.f2.

PMID:
19131733
24.

AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma.

Albertus DL, Seder CW, Chen G, Wang X, Hartojo W, Lin L, Silvers A, Thomas DG, Giordano TJ, Chang AC, Orringer MB, Bigbee WL, Chinnaiyan AM, Beer DG.

J Thorac Oncol. 2008 Nov;3(11):1236-44. doi: 10.1097/JTO.0b013e318189f5ec.

25.

Use of novel autoantibody and cancer-related protein arrays for the detection of esophageal adenocarcinoma in serum.

Kilic A, Schuchert MJ, Luketich JD, Landreneau RJ, Lokshin AE, Bigbee WL, El-Hefnawy T.

J Thorac Cardiovasc Surg. 2008 Jul;136(1):199-204. doi: 10.1016/j.jtcvs.2008.01.012. Epub 2008 May 22.

26.

SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer.

McLerran D, Grizzle WE, Feng Z, Thompson IM, Bigbee WL, Cazares LH, Chan DW, Dahlgren J, Diaz J, Kagan J, Lin DW, Malik G, Oelschlager D, Partin A, Randolph TW, Sokoll L, Srivastava S, Srivastava S, Thornquist M, Troyer D, Wright GL, Zhang Z, Zhu L, Semmes OJ.

Clin Chem. 2008 Jan;54(1):53-60. Epub 2007 Nov 16.

27.

Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias.

McLerran D, Grizzle WE, Feng Z, Bigbee WL, Banez LL, Cazares LH, Chan DW, Diaz J, Izbicka E, Kagan J, Malehorn DE, Malik G, Oelschlager D, Partin A, Randolph T, Rosenzweig N, Srivastava S, Srivastava S, Thompson IM, Thornquist M, Troyer D, Yasui Y, Zhang Z, Zhu L, Semmes OJ.

Clin Chem. 2008 Jan;54(1):44-52. Epub 2007 Nov 2.

28.

Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer.

Yildiz PB, Shyr Y, Rahman JS, Wardwell NR, Zimmerman LJ, Shakhtour B, Gray WH, Chen S, Li M, Roder H, Liebler DC, Bigbee WL, Siegfried JM, Weissfeld JL, Gonzalez AL, Ninan M, Johnson DH, Carbone DP, Caprioli RM, Massion PP.

J Thorac Oncol. 2007 Oct;2(10):893-901.

29.

Intersession reproducibility of mass spectrometry profiles and its effect on accuracy of multivariate classification models.

Pelikan R, Bigbee WL, Malehorn D, Lyons-Weiler J, Hauskrecht M.

Bioinformatics. 2007 Nov 15;23(22):3065-72. Epub 2007 Aug 30.

PMID:
17766268
30.

Serum proteomic patterns as a predictor of severity in acute pancreatitis.

Papachristou GI, Malehorn DE, Lamb J, Slivka A, Bigbee WL, Whitcomb DC.

Pancreatology. 2007;7(4):317-24. Epub 2007 Jul 11.

PMID:
17627096
31.

Multiple cytokine and growth factor serum biomarkers predict therapeutic response and survival in advanced-stage head and neck cancer patients.

Bigbee WL, Grandis JR, Siegfried JM.

Clin Cancer Res. 2007 Jun 1;13(11):3107-8. No abstract available.

32.

Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma.

Chen G, Wang X, Yu J, Varambally S, Yu J, Thomas DG, Lin MY, Vishnu P, Wang Z, Wang R, Fielhauer J, Ghosh D, Giordano TJ, Giacherio D, Chang AC, Orringer MB, El-Hefnawy T, Bigbee WL, Beer DG, Chinnaiyan AM.

Cancer Res. 2007 Apr 1;67(7):3461-7.

33.

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

Escobar PA, Olivero OA, Wade NA, Abrams EJ, Nesel CJ, Ness RB, Day RD, Day BW, Meng Q, O'Neill JP, Walker DM, Poirier MC, Walker VE, Bigbee WL.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):330-43.

PMID:
17358027
34.

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs.

Meng Q, Olivero OA, Fasco MJ, Bellisario R, Kaminsky L, Pass KA, Wade NA, Abrams EJ, Nesel CJ, Ness RB, Bigbee WL, O'Neill JP, Walker DM, Poirier MC, Walker VE.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):307-21.

PMID:
17358024
35.

Multianalyte profiling of serum cytokines for detection of pancreatic cancer.

Zeh HJ, Winikoff S, Landsittel DP, Gorelik E, Marrangoni AM, Velikokhatnaya L, Winans MT, Lee K, Moser A, Bartlett D, Lotze MT, Siegfried JM, Whitcomb D, Papacristou G, Slivka A, Bigbee WL, Lokshin AE.

Cancer Biomark. 2005;1(6):259-69. Erratum in: Cancer Biomark. 2006;2(3-4):175. Papacristou, G [added].

PMID:
17192050
36.

The absence of interaction between drug metabolizing enzyme genotypes and maternal lifestyle factors on glycophorin A somatic mutation frequency levels in newborns.

Nukui T, Day RD, Gordish-Dressman HA, Harger G, Bigbee WL, Ness RB, Romkes M.

Pharmacogenet Genomics. 2006 Feb;16(2):129-38.

PMID:
16424825
37.

Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles.

Hauskrecht M, Pelikan R, Malehorn DE, Bigbee WL, Lotze MT, Zeh HJ, Whitcomb DC, Lyons-Weiler J.

Appl Bioinformatics. 2005;4(4):227-46.

PMID:
16309341
38.

Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy.

Miyamae T, Malehorn DE, Lemster B, Mori M, Imagawa T, Yokota S, Bigbee WL, Welsh M, Klarskov K, Nishomoto N, Vallejo AN, Hirsch R.

Arthritis Res Ther. 2005;7(4):R746-55. Epub 2005 Apr 4.

39.

Multiplexed immunobead-based cytokine profiling for early detection of ovarian cancer.

Gorelik E, Landsittel DP, Marrangoni AM, Modugno F, Velikokhatnaya L, Winans MT, Bigbee WL, Herberman RB, Lokshin AE.

Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):981-7.

40.

HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy.

Keohavong P, Xi L, Day RD, Zhang L, Grant SG, Day BW, Ness RB, Bigbee WL.

Mutat Res. 2005 May 2;572(1-2):156-66.

PMID:
15790499
41.

Multiplexed analysis of serum cytokines as biomarkers in squamous cell carcinoma of the head and neck patients.

Hathaway B, Landsittel DP, Gooding W, Whiteside TL, Grandis JR, Siegfried JM, Bigbee WL, Ferris RL.

Laryngoscope. 2005 Mar;115(3):522-7.

PMID:
15744170
43.

Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.

Semmes OJ, Feng Z, Adam BL, Banez LL, Bigbee WL, Campos D, Cazares LH, Chan DW, Grizzle WE, Izbicka E, Kagan J, Malik G, McLerran D, Moul JW, Partin A, Prasanna P, Rosenzweig J, Sokoll LJ, Srivastava S, Srivastava S, Thompson I, Welsh MJ, White N, Winget M, Yasui Y, Zhang Z, Zhu L.

Clin Chem. 2005 Jan;51(1):102-12.

44.

Glycophorin A is a potential biomarker for the mutagenic effects of pesticides.

Takaro TK, Engel LS, Keifer M, Bigbee WL, Kavanagh TJ, Checkoway H.

Int J Occup Environ Health. 2004 Jul-Sep;10(3):256-61.

PMID:
15473078
45.

Glycophorin A somatic cell mutations in a population living in the proximity of the Semipalatinsk nuclear test site.

Lindholm C, Murphy BP, Bigbee WL, Bersimbaev RI, Hultén MA, Dubrova YE, Salomaa S.

Radiat Res. 2004 Aug;162(2):164-70.

PMID:
15387144
46.

Serum protein expression profiling for cancer detection: validation of a SELDI-based approach for prostate cancer.

Grizzle WE, Adam BL, Bigbee WL, Conrads TP, Carroll C, Feng Z, Izbicka E, Jendoubi M, Johnsey D, Kagan J, Leach RJ, McCarthy DB, Semmes OJ, Srivastava S, Srivastava S, Thompson IM, Thornquist MD, Verma M, Zhang Z, Zou Z.

Dis Markers. 2003-2004;19(4-5):185-95.

47.

Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics.

El-Hefnawy T, Raja S, Kelly L, Bigbee WL, Kirkwood JM, Luketich JD, Godfrey TE.

Clin Chem. 2004 Mar;50(3):564-73. Epub 2004 Jan 12.

48.

Cancer mortality in counties near two former nuclear materials processing facilities in Pennsylvania, 1950-1995.

Boice JD Jr, Bigbee WL, Mumma MT, Blot WJ.

Health Phys. 2003 Dec;85(6):691-700.

PMID:
14626320
49.

Cancer incidence in municipalities near two former nuclear materials processing facilities in Pennsylvania.

Boice JD Jr, Bigbee WL, Mumma MT, Blot WJ.

Health Phys. 2003 Dec;85(6):678-90.

PMID:
14626319
50.

Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation.

Gorbunov NV, Pogue-Geile KL, Epperly MW, Bigbee WL, Draviam R, Day BW, Wald N, Watkins SC, Greenberger JS.

Radiat Res. 2000 Jul;154(1):73-86.

PMID:
10856968

Supplemental Content

Loading ...
Support Center