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Items: 1 to 50 of 304

1.

Impact of multipoint pacing on projected battery longevity in cardiac resynchronization therapy. An IRON-MPP study sub-analysis.

Forleo GB, Gasperetti A, Ricciardi D, Curnis A, Bertaglia E, Calò L, Pignalberi C, Calzolari V, Ribatti V, Lavalle C, Potenza D, Tondi L, Natale V, Notarstefano P, Viecca M, Morani G, Biffi M, Giammaria M, Zanon F, Santini L.

J Cardiovasc Electrophysiol. 2019 Oct 29. doi: 10.1111/jce.14254. [Epub ahead of print]

PMID:
31661172
2.

Are Atrial High-Rate Episodes Associated With Increased Risk of Ventricular Arrhythmias and Mortality?

Vergara P, Solimene F, D'Onofrio A, Pisanò EC, Zanotto G, Pignalberi C, Iacopino S, Maglia G, Della Bella P, Calvi V, Curnis A, Senatore G, Biffi M, Capucci A, Parisi Q, Quartieri F, Caravati F, Giammaria M, Marini M, Rapacciuolo A, Manzo M, Giacopelli D, Gargaro A, Ricci RP.

JACC Clin Electrophysiol. 2019 Oct;5(10):1197-1208. doi: 10.1016/j.jacep.2019.06.018. Epub 2019 Aug 28.

PMID:
31648745
3.

Temporal patterns of premature atrial complexes predict atrial fibrillation occurrence in bradycardia patients continuously monitored through pacemaker diagnostics.

Boriani G, Botto GL, Pieragnoli P, Ricci R, Biffi M, Marini M, Sagone A, Avella A, Pignalberi C, Ziacchi M, Ricciardi G, Tartaglione E, Grammatico A, Gasparini M.

Intern Emerg Med. 2019 Sep 9. doi: 10.1007/s11739-019-02182-5. [Epub ahead of print]

PMID:
31502237
4.

Lead choice in cardiac implantable electronic devices: an Italian survey promoted by AIAC (Italian Association of Arrhythmias and Cardiac Pacing).

Ziacchi M, Palmisano P, Biffi M, Guerra F, Stabile G, Forleo GB, Zanotto G, D'Onofrio A, Landolina M, De Ponti R, Zoni Berisso M, Ricci RP, Boriani G.

Expert Rev Med Devices. 2019 Sep;16(9):821-828. doi: 10.1080/17434440.2019.1649134. Epub 2019 Aug 5.

PMID:
31348864
5.

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation.

Boriani G, Biffi M.

N Engl J Med. 2019 Jul 25;381(4):385-386. doi: 10.1056/NEJMc1906729. No abstract available.

PMID:
31340101
6.

Automatic verification of capture in the scenario of His bundle pacing: still an unmet need?

Massaro G, Lorenzetti S, Statuto G, Biffi M.

J Cardiovasc Electrophysiol. 2019 Oct;30(10):2110-2112. doi: 10.1111/jce.14085. Epub 2019 Jul 23. No abstract available.

PMID:
31328351
7.

Rate-responsive pacing and atrial high rate episodes in cardiac resynchronization therapy patients: Is low heart rate the key?

Biffi M, D'Onofrio A, Pignalberi C, Pisanò EC, Iacopino S, Curnis A, Senatore G, Capucci A, Della Bella P, Calvi V, Zanotto G, Caravati F, Maglia G, Manzo M, Santamaria M, Ziacchi M, Lissoni F, Giacopelli D, Gargaro A, Solimene F.

Clin Cardiol. 2019 Jul 7. doi: 10.1002/clc.23227. [Epub ahead of print]

8.

Real-life outcome of implantable cardioverter-defibrillator and cardiac resynchronization defibrillator replacement/upgrade in a contemporary population: observations from the multicentre DECODE registry.

Biffi M, Ammendola E, Menardi E, Parisi Q, Narducci ML, De Filippo P, Manzo M, Stabile G, Potenza DR, Zanon F, Quartieri F, Rillo M, Saporito D, Zacà V, Berisso MZ, Bertini M, Tumietto F, Malacrida M, Diemberger I.

Europace. 2019 Oct 1;21(10):1527-1536. doi: 10.1093/europace/euz166.

PMID:
31209482
9.

Less invasive ventricular enhancement (LIVE) as potential therapy for ischaemic cardiomyopathy end-stage heart failure.

Loforte A, Alfonsi J, Gliozzi G, Folesani G, Fiorentino M, Biffi M, Marinelli G, Di Bartolomeo R, Pacini D.

J Thorac Dis. 2019 Apr;11(Suppl 6):S921-S928. doi: 10.21037/jtd.2019.02.86.

10.

The never-ending story of CIED infection prevention: Shall we WRAP-IT and go?

Biffi M.

J Cardiovasc Electrophysiol. 2019 Aug;30(8):1191-1196. doi: 10.1111/jce.14010. Epub 2019 Jul 9.

PMID:
31172637
11.

Long-term outcomes after prophylactic ICD and CRT-D implantation in nonischemic patients: Analysis from a nationwide database of daily remote-monitoring transmissions.

Forleo GB, Solimene F, Pisanò EC, Zanotto G, Calvi V, Pignalberi C, Maglia G, Iacopino S, Quartieri F, Biffi M, Caravati F, Curnis A, Capucci A, Senatore G, Santamaria M, Della Bella P, Manzo M, Giacopelli D, Gargaro A, D'Onofrio A.

J Cardiovasc Electrophysiol. 2019 Sep;30(9):1626-1635. doi: 10.1111/jce.14006. Epub 2019 Jun 18.

PMID:
31165517
12.

Time to therapy delivery and effectiveness of the subcutaneous implantable cardioverter-defibrillator.

Diemberger I, Migliore F, Ricciardi G, Ottaviano L, Tavoletta V, Francia P, Viani S, Capucci A, de Filippo P, Nigro G, Caravati F, Palmisano P, Ziacchi M, Lovecchio M, Valsecchi S, Bongiorni MG, Biffi M; “S-ICD Rhythm Detect” Investigators.

Heart Rhythm. 2019 Oct;16(10):1531-1537. doi: 10.1016/j.hrthm.2019.05.028. Epub 2019 May 29.

PMID:
31150817
13.

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates.

Milani M, Annoni A, Moalli F, Liu T, Cesana D, Calabria A, Bartolaccini S, Biffi M, Russo F, Visigalli I, Raimondi A, Patarroyo-White S, Drager D, Cristofori P, Ayuso E, Montini E, Peters R, Iannacone M, Cantore A, Naldini L.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7325. doi: 10.1126/scitranslmed.aav7325.

PMID:
31118293
14.

Effect of lead design and pacing vector on electrical parameters of quadripolar coronary sinus leads: The RALLY-X4 study.

Burri H, Schrage MO, Morani G, Sakata Y, Hermida JS, Solimene F, Rauwolf T, Kayser T, Pakarinen S, Biffi M.

Pacing Clin Electrophysiol. 2019 Jul;42(7):1018-1025. doi: 10.1111/pace.13716. Epub 2019 May 20.

PMID:
31050004
15.

Wireless Endocardial Atrial (and Ventricular) Sensing with no Implanted Power Source: a Proposal.

Corazza I, Diemberger I, Martignani C, Ziacchi M, Rossi PL, Lombi A, Zannoli R, Biffi M.

J Med Syst. 2019 Apr 26;43(6):159. doi: 10.1007/s10916-019-1277-6.

PMID:
31028553
16.

Successful defibrillation verification in subcutaneous implantable cardioverter-defibrillator recipients by low-energy shocks.

Biffi M, Ziacchi M, Angeletti A, Castelli A, Massaro G, Martignani C, Lovecchio M, Valsecchi S, Diemberger I.

Clin Cardiol. 2019 Jun;42(6):612-617. doi: 10.1002/clc.23184. Epub 2019 Apr 25.

17.

Percutaneous Pulmonary Artery Venting via Jugular Vein While on Peripheral Extracorporeal Life Support.

Loforte A, Baiocchi M, Dal Checco E, Gliozzi G, Fiorentino M, Lo Coco V, Martin Suarez S, Marrozzini C, Biffi M, Marinelli G, Pacini D.

ASAIO J. 2019 Mar 19. doi: 10.1097/MAT.0000000000000991. [Epub ahead of print]

PMID:
30908287
18.

Antibacterial Envelope to Prevent Cardiac Implantable Device Infection.

Tarakji KG, Mittal S, Kennergren C, Corey R, Poole JE, Schloss E, Gallastegui J, Pickett RA, Evonich R, Philippon F, McComb JM, Roark SF, Sorrentino D, Sholevar D, Cronin E, Berman B, Riggio D, Biffi M, Khan H, Silver MT, Collier J, Eldadah Z, Wright DJ, Lande JD, Lexcen DR, Cheng A, Wilkoff BL; WRAP-IT Investigators.

N Engl J Med. 2019 May 16;380(20):1895-1905. doi: 10.1056/NEJMoa1901111. Epub 2019 Mar 17.

PMID:
30883056
19.

Bipolar active fixation left ventricular lead or quadripolar passive fixation lead? An Italian multicenter experience.

Ziacchi M, Giannola G, Lunati M, Infusino T, Luzzi G, Rordorf R, Pecora D, Bongiorni MG, De Ruvo E, Biffi M.

J Cardiovasc Med (Hagerstown). 2019 Apr;20(4):192-200. doi: 10.2459/JCM.0000000000000778.

PMID:
30762662
20.

Effect of PR interval and pacing mode on persistent atrial fibrillation incidence in dual chamber pacemaker patients: a sub-study of the international randomized MINERVA trial.

Boriani G, Pieragnoli P, Botto GL, Puererfellner H, Mont L, Ziacchi M, Manolis AS, Gulizia M, Tukkie R, Landolina M, Ricciardi G, Cicconelli M, Grammatico A, Biffi M.

Europace. 2019 Apr 1;21(4):636-644. doi: 10.1093/europace/euy286.

PMID:
30649270
21.

Performance and clinical comparison between left ventricular quadripolar and bipolar leads in cardiac resynchronization therapy: Observational research.

Ziacchi M, Zucchelli G, Ricciardi D, Morani G, De Ruvo E, Calzolari V, Viani S, Calabrese V, Tomasi L, Calò L, De Mattia L, Bongiorni MG, Boriani G, Biffi M.

Indian Heart J. 2018 Nov - Dec;70(6):864-871. doi: 10.1016/j.ihj.2018.05.007. Epub 2018 May 16.

22.

An indissoluble knot: An unexpected troubleshooting during Micra implantation.

Cipolletta L, Volpato G, Biffi M, Capucci A.

Pacing Clin Electrophysiol. 2019 Jun;42(6):747-748. doi: 10.1111/pace.13584. Epub 2018 Dec 27.

PMID:
30552694
23.

Use and outcomes of subcutaneous implantable cardioverter-defibrillator (ICD) after transvenous ICD extraction: An analysis of current clinical practice and a comparison with transvenous ICD reimplantation.

Viani S, Migliore F, Tola G, Pisanò ECL, Russo AD, Luzzi G, Sartori P, Piro A, Rordorf R, Forleo GB, Rago A, Segreti L, Bertaglia E, Biffi M, Lovecchio M, Valsecchi S, Diemberger I, Bongiorni MG.

Heart Rhythm. 2019 Apr;16(4):564-571. doi: 10.1016/j.hrthm.2018.10.026. Epub 2018 Oct 24.

PMID:
30366163
24.

Seasonal trend of ventricular arrhythmias in a nationwide remote monitoring database of implantable defibrillators and cardiac resynchronization devices.

Russo V, Solimene F, Zanotto G, Pisanò EC, Della Bella P, Iacopino S, Pignalberi C, Calvi V, Maglia G, Quartieri F, Biffi M, Curnis A, Giacopelli D, Gargaro A, D'Onofrio A.

Int J Cardiol. 2019 Jan 15;275:104-106. doi: 10.1016/j.ijcard.2018.10.025. Epub 2018 Oct 10.

PMID:
30327133
25.

Comparison of cryoballoon and radiofrequency ablation techniques for atrial fibrillation: a meta-analysis.

Maltoni S, Negro A, Camerlingo MD, Pecoraro V, Sassone B, Biffi M, Boriani G.

J Cardiovasc Med (Hagerstown). 2018 Dec;19(12):725-738. doi: 10.2459/JCM.0000000000000725.

PMID:
30320723
26.

Leadless left ventricular endocardial pacing: a real alternative or a luxury for a few?

De Maria E, Ziacchi M, Diemberger I, Biffi M.

Cardiovasc Diagn Ther. 2018 Aug;8(4):530-533. doi: 10.21037/cdt.2018.03.08. No abstract available.

27.

Contribution of PET imaging to mortality risk stratification in candidates to lead extraction for pacemaker or defibrillator infection: a prospective single center study.

Diemberger I, Bonfiglioli R, Martignani C, Graziosi M, Biffi M, Lorenzetti S, Ziacchi M, Nanni C, Fanti S, Boriani G.

Eur J Nucl Med Mol Imaging. 2019 Jan;46(1):194-205. doi: 10.1007/s00259-018-4142-9. Epub 2018 Sep 8.

PMID:
30196365
28.

Cardiac resynchronization therapy: a comparison among left ventricular bipolar, quadripolar and active fixation leads.

Ziacchi M, Diemberger I, Corzani A, Martignani C, Mazzotti A, Massaro G, Valzania C, Rapezzi C, Boriani G, Biffi M.

Sci Rep. 2018 Sep 5;8(1):13262. doi: 10.1038/s41598-018-31692-z.

29.

Electrical manipulation of the failing heart.

Zacà V, Murphy T, Biffi M.

Heart Fail Rev. 2018 Nov;23(6):885-896. doi: 10.1007/s10741-018-9732-x. Review.

PMID:
30099646
30.

Subcutaneous implantable cardioverter defibrillator implantation: An analysis of Italian clinical practice and its evolution.

D'Onofrio A, Pieragnoli P, Biffi M, Nigro G, Migliore F, Francia P, De Filippo P, Capucci A, Botto GL, Giammaria M, Palmisano P, Pisanò E, Bisignani G, La Greca C, Sarubbi B, Sala S, Viscusi M, Landolina M, Lovecchio M, Valsecchi S, Bongiorni MG; "S-ICD Rhythm Detect" Investigators.

Int J Cardiol. 2018 Dec 1;272:162-167. doi: 10.1016/j.ijcard.2018.07.139. Epub 2018 Jul 31.

PMID:
30087041
31.

Is ventricular sensing always right, when it is left?

Biffi M, de Zan G, Massaro G, Angeletti A, Martignani C, Boriani G, Diemberger I, Ziacchi M.

Clin Cardiol. 2018 Sep;41(9):1238-1245. doi: 10.1002/clc.23033. Epub 2018 Sep 21.

32.

Impact of pacemaker longevity on expected device replacement rates: Results from computer simulations based on a multicenter registry (ESSENTIAL).

Boriani G, Bertini M, Saporito D, Belotti G, Quartieri F, Tomasi C, Pucci A, Boggian G, Mazzocca GF, Giorgi D, Diotallevi P, Sassone B, Grassini D, Gargaro A, Biffi M; on the behalf of ESSENTIAL Investigators.

Clin Cardiol. 2018 Sep;41(9):1185-1191. doi: 10.1002/clc.23003. Epub 2018 Sep 22.

33.

Long-term progression of rhythm and conduction disturbances in pacemaker recipients: findings from the Pacemaker Expert Programming study.

Palmisano P, Ziacchi M, Ammendola E, Dell'Era G, Guerra F, Aspromonte V, Boriani G, Nigro G, Occhetta E, Capucci A, Ricci RP, Maglia G, Biffi M, Accogli M; Italian Association of Arrhythmology, Cardiac Pacing (AIAC).

J Cardiovasc Med (Hagerstown). 2018 Jul;19(7):357-365. doi: 10.2459/JCM.0000000000000673.

PMID:
29846304
34.

Long-term electrical performance of Attain Performa quadripolar left ventricular leads with all steroid-eluting electrodes: Results from a large worldwide clinical trial.

Lin AC, Biffi M, Exner DV, Johnson WB, Gras D, Hussin A, Singh B, Yang Z, Hine D, Li S, Crossley GH.

Pacing Clin Electrophysiol. 2018 May 29. doi: 10.1111/pace.13389. [Epub ahead of print]

PMID:
29808920
35.

Benefits of left ventricular endocardial pacing comparing failed implants and prior non-responders to conventional cardiac resynchronization therapy: A subanalysis from the ALSYNC study.

Biffi M, Defaye P, Jaïs P, Ruffa F, Leclercq C, Gras D, Yang Z, Gerritse B, Ziacchi M, Morgan JM; ALSYNC Investigators.

Int J Cardiol. 2018 May 15;259:88-93. doi: 10.1016/j.ijcard.2018.01.030.

PMID:
29579617
36.

Atrial fibrillation and prediction of mortality by conventional clinical score systems according to the setting of care.

Diemberger I, Fantecchi E, Reggiani MLB, Martignani C, Angeletti A, Massaro G, Ziacchi M, Biffi M, Lip GYH, Boriani G.

Int J Cardiol. 2018 Jun 15;261:73-77. doi: 10.1016/j.ijcard.2018.03.058. Epub 2018 Mar 14.

PMID:
29572083
37.

External implantable defibrillator as a bridge to reimplant after explant for infection: Experience from two centers.

Dell'Era G, Ziacchi M, Prenna E, Diemberger I, Varalda M, Martignani C, Guerra F, Biffi M, Occhetta E.

Pacing Clin Electrophysiol. 2018 May;41(5):532-535. doi: 10.1111/pace.13320. Epub 2018 Apr 15.

PMID:
29518264
38.

Subcutaneous implantable cardioverter defibrillator eligibility according to a novel automated screening tool and agreement with the standard manual electrocardiographic morphology tool.

Francia P, Ziacchi M, De Filippo P, Viani S, D'Onofrio A, Russo V, Adduci C, Biffi M, Ferrari P, Bianchi V, Ammendola E, Palano F, Frisoni J, Valsecchi S, Lovecchio M, Bongiorni MG.

J Interv Card Electrophysiol. 2018 Jun;52(1):61-67. doi: 10.1007/s10840-018-0326-2. Epub 2018 Mar 3.

PMID:
29502193
39.

Does the CHA2DS2-VASc score reliably predict atrial arrhythmias? Analysis of a nationwide database of remote monitoring data transmitted daily from cardiac implantable electronic devices.

Rovaris G, Solimene F, D'Onofrio A, Zanotto G, Ricci RP, Mazzella T, Iacopino S, Della Bella P, Maglia G, Senatore G, Quartieri F, Biffi M, Curnis A, Calvi V, Rapacciuolo A, Santamaria M, Capucci A, Giammaria M, Campana A, Caravati F, Giacopelli D, Gargaro A, Pisanò EC.

Heart Rhythm. 2018 Jul;15(7):971-979. doi: 10.1016/j.hrthm.2018.02.023. Epub 2018 Mar 1.

PMID:
29477974
40.

Clinically oriented device programming in bradycardia patients: part 2 (atrioventricular blocks and neurally mediated syncope). Proposals from AIAC (Italian Association of Arrhythmology and Cardiac Pacing).

Palmisano P, Ziacchi M, Biffi M, Ricci RP, Landolina M, Zoni-Berisso M, Occhetta E, Maglia G, Botto G, Padeletti L, Boriani G; Italian Association of Arrhythmology and Cardiac Pacing (AIAC).

J Cardiovasc Med (Hagerstown). 2018 Apr;19(4):170-180. doi: 10.2459/JCM.0000000000000629. Review.

PMID:
29470251
41.

Clinically oriented device programming in bradycardia patients: part 1 (sinus node disease). Proposals from AIAC (Italian Association of Arrhythmology and Cardiac Pacing).

Ziacchi M, Palmisano P, Biffi M, Ricci RP, Landolina M, Zoni-Berisso M, Occhetta E, Maglia G, Botto G, Padeletti L, Boriani G; Italian Association of Arrhythmology and Cardiac Pacing (AIAC).

J Cardiovasc Med (Hagerstown). 2018 Apr;19(4):161-169. doi: 10.2459/JCM.0000000000000630. Review.

PMID:
29470250
42.

Atrioventricular junction ablation in patients with atrial fibrillation treated with cardiac resynchronization therapy: positive impact on ventricular arrhythmias, implantable cardioverter-defibrillator therapies and hospitalizations.

Gasparini M, Kloppe A, Lunati M, Anselme F, Landolina M, Martinez-Ferrer JB, Proclemer A, Morani G, Biffi M, Ricci R, Rordorf R, Mangoni L, Manotta L, Grammatico A, Leyva F, Boriani G.

Eur J Heart Fail. 2018 Oct;20(10):1472-1481. doi: 10.1002/ejhf.1117. Epub 2017 Dec 18.

43.

Appropriate implantable cardioverter-defibrillator interventions in cardiac resynchronization therapy-defibrillator (CRT-D) patients undergoing device replacement: time to downgrade from CRT-D to CRT-pacemaker? Insights from real-world clinical practice in the DECODE CRT-D analysis.

Narducci ML, Biffi M, Ammendola E, Vado A, Campana A, Potenza DR, Iori M, Zanon F, Zacà V, Zoni Berisso M, Bertini M, Lissoni F, Bandini A, Malacrida M, Crea F.

Europace. 2018 Sep 1;20(9):1475-1483. doi: 10.1093/europace/eux323.

PMID:
29186401
44.

The "Subtle" connection between development of cardiac implantable electrical device infection and survival after complete system removal: An observational prospective multicenter study.

Diemberger I, Migliore F, Biffi M, Cipriani A, Bertaglia E, Lorenzetti S, Massaro G, Tanzarella G, Boriani G.

Int J Cardiol. 2018 Jan 1;250:146-149. doi: 10.1016/j.ijcard.2017.07.061. Epub 2017 Oct 9.

PMID:
29032885
45.

Manufacturer change and risk of system-related complications after implantable cardioverter defibrillator replacement: physicians' survey and data from the Detect Long-term Complications After Implantable Cardioverter Defibrillator Replacement Registry.

Biffi M, Menardi E, Narducci ML, Ammendola E, Messano L, Giofrè F, Baiocchi C, Saporito D, Lissoni F, Bertini M, Pierantozzi A, Zingarini G, Malacrida M, Ziacchi M.

J Cardiovasc Med (Hagerstown). 2017 Dec;18(12):968-975. doi: 10.2459/JCM.0000000000000572.

PMID:
29028784
46.

Predictors of long-term survival free from relapses after extraction of infected CIED.

Diemberger I, Biffi M, Lorenzetti S, Martignani C, Raffaelli E, Ziacchi M, Rapezzi C, Pacini D, Boriani G.

Europace. 2018 Jun 1;20(6):1018-1027. doi: 10.1093/europace/eux121.

PMID:
29016771
47.

Less is more: Can we achieve cardiac resynchronization with 2 leads only?

Biffi M, Massaro G, Candelora A, Angeletti A, Valzania C, Martignani C, Grassini D, Diemberger I, Ziacchi M.

Int J Cardiol. 2017 Dec 15;249:184-190. doi: 10.1016/j.ijcard.2017.09.189. Epub 2017 Sep 24.

PMID:
28966043
48.

Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy.

Milani M, Annoni A, Bartolaccini S, Biffi M, Russo F, Di Tomaso T, Raimondi A, Lengler J, Holmes MC, Scheiflinger F, Lombardo A, Cantore A, Naldini L.

EMBO Mol Med. 2017 Nov;9(11):1558-1573. doi: 10.15252/emmm.201708148.

49.

Effects of cardiac resynchronization therapy on right ventricular function during rest and exercise, as assessed by radionuclide angiography, and on NT-proBNP levels.

Valzania C, Biffi M, Bonfiglioli R, Fallani F, Martignani C, Diemberger I, Ziacchi M, Frisoni J, Tomasi L, Fanti S, Rapezzi C, Boriani G.

J Nucl Cardiol. 2019 Feb;26(1):123-132. doi: 10.1007/s12350-017-0971-3. Epub 2017 Jun 30.

PMID:
28667454
50.

Cardiac resynchronization therapy and electrical storm: results of the OBSERVational registry on long-term outcome of ICD patients (OBSERVO-ICD).

Guerra F, Palmisano P, Dell'Era G, Ziacchi M, Ammendola E, Pongetti G, Bonelli P, Patani F, Devecchi C, Accogli M, Occhetta E, Nigro G, Biffi M, Boriani G, Capucci A; Italian Association of Arrhythmology and Cardiac Pacing (AIAC).

Europace. 2018 Jun 1;20(6):979-985. doi: 10.1093/europace/eux166.

PMID:
28595339

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