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Items: 35


Alternative trafficking of Weibel-Palade body proteins in CRISPR/Cas9-engineered von Willebrand factor-deficient blood outgrowth endothelial cells.

Schillemans M, Kat M, Westeneng J, Gangaev A, Hofman M, Nota B, van Alphen FPJ, de Boer M, van den Biggelaar M, Margadant C, Voorberg J, Bierings R.

Res Pract Thromb Haemost. 2019 Aug 1;3(4):718-732. doi: 10.1002/rth2.12242. eCollection 2019 Oct.


WPBs: making a mark and leaving a trail.

Carter T, Bierings R.

Blood. 2019 Sep 19;134(12):909-910. doi: 10.1182/blood.2019002322. No abstract available.


Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.

Schillemans M, Karampini E, Hoogendijk AJ, Wahedi M, van Alphen FPJ, van den Biggelaar M, Voorberg J, Bierings R.

J Proteomics. 2019 Aug 15;205:103417. doi: 10.1016/j.jprot.2019.103417. Epub 2019 Jun 13.


Chronotyping glaucoma patients with the Munich ChronoType Questionnaire: A case-control study.

Bierings RAJM, Gordijn MCM, Jansonius NM.

PLoS One. 2019 Mar 28;14(3):e0214046. doi: 10.1371/journal.pone.0214046. eCollection 2019.


Spatial contrast sensitivity from star- to sunlight in healthy subjects and patients with glaucoma.

Bierings RAJM, Overkempe T, van Berkel CM, Kuiper M, Jansonius NM.

Vision Res. 2019 May;158:31-39. doi: 10.1016/j.visres.2019.01.011. Epub 2019 Feb 23.


Synaptotagmin 5 regulates Ca2+-dependent Weibel-Palade body exocytosis in human endothelial cells.

Lenzi C, Stevens J, Osborn D, Hannah MJ, Bierings R, Carter T.

J Cell Sci. 2019 Feb 15;132(5). pii: jcs221952. doi: 10.1242/jcs.221952.


Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R.

Haematologica. 2019 Oct;104(10):2091-2099. doi: 10.3324/haematol.2018.207787. Epub 2019 Jan 10.


Exocytosis of Weibel-Palade bodies: how to unpack a vascular emergency kit.

Schillemans M, Karampini E, Kat M, Bierings R.

J Thromb Haemost. 2019 Jan;17(1):6-18. doi: 10.1111/jth.14322. Epub 2018 Dec 13. Review.


Visual Performance as a Function of Luminance in Glaucoma: The De Vries-Rose, Weber's, and Ferry-Porter's Law.

Bierings RAJM, de Boer MH, Jansonius NM.

Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3416-3423. doi: 10.1167/iovs.17-22497.


Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans M, Karampini E, van den Eshof BL, Gangaev A, Hofman M, van Breevoort D, Meems H, Janssen H, Mulder AA, Jost CR, Escher JC, Adam R, Carter T, Koster AJ, van den Biggelaar M, Voorberg J, Bierings R.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1549-1561. doi: 10.1161/ATVBAHA.117.310701. Epub 2018 Jun 7.


A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation.

Rijkers M, Saris A, Heidt S, Mulder A, Porcelijn L, Claas FHJ, Bierings R, Leebeek FWG, Jansen AJG, Vidarsson G, Voorberg J, de Haas M.

Haematologica. 2018 Oct;103(10):1741-1752. doi: 10.3324/haematol.2018.189365. Epub 2018 Jun 1.


Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

Smeets MWJ, Bierings R, Meems H, Mul FPJ, Geerts D, Vlaar APJ, Voorberg J, Hordijk PL.

PLoS One. 2018 Mar 21;13(3):e0194958. doi: 10.1371/journal.pone.0194958. eCollection 2018.


Visual complaints of patients with glaucoma and controls under optimal and extreme luminance conditions.

Bierings RAJM, van Sonderen FLP, Jansonius NM.

Acta Ophthalmol. 2018 May;96(3):288-294. doi: 10.1111/aos.13695. Epub 2018 Mar 9.


Foveal light and dark adaptation in patients with glaucoma and healthy subjects: A case-control study.

Bierings RAJM, Kuiper M, van Berkel CM, Overkempe T, Jansonius NM.

PLoS One. 2018 Mar 6;13(3):e0193663. doi: 10.1371/journal.pone.0193663. eCollection 2018.


Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

Smeets MW, Bierings R, Meems H, Mul FP, Geerts D, Vlaar AP, Voorberg J, Hordijk PL.

PLoS One. 2017 Mar 1;12(3):e0173077. doi: 10.1371/journal.pone.0173077. eCollection 2017. Erratum in: PLoS One. 2018 Mar 21;13(3):e0194958.


Up or out: polarity of VWF release.

Bierings R, Voorberg J.

Blood. 2016 Jul 14;128(2):154-5. doi: 10.1182/blood-2016-05-713057. No abstract available.


Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis.

Conte IL, Hellen N, Bierings R, Mashanov GI, Manneville JB, Kiskin NI, Hannah MJ, Molloy JE, Carter T.

J Cell Sci. 2016 Feb 1;129(3):592-603. doi: 10.1242/jcs.178285. Epub 2015 Dec 16.


Is there more than one way to unpack a Weibel-Palade body?

Conte IL, Cookson E, Hellen N, Bierings R, Mashanov G, Carter T.

Blood. 2015 Oct 29;126(18):2165-7. doi: 10.1182/blood-2015-08-664961. Epub 2015 Sep 16. No abstract available.


The prion protein inhibits monocytic cell migration by stimulating β1 integrin adhesion and uropod formation.

Richardson DD, Tol S, Valle-Encinas E, Pleguezuelos C, Bierings R, Geerts D, Fernandez-Borja M.

J Cell Sci. 2015 Aug 15;128(16):3018-29. doi: 10.1242/jcs.165365. Epub 2015 Jul 9.


Individual with subclinical atherosclerosis have impaired proliferation of blood outgrowth endothelial cells, which can be restored by statin therapy.

Martin-Ramirez J, Kok MG, Hofman M, Bierings R, Creemers EE, Meijers JC, Voorberg J, Pinto-Sietsma SJ.

PLoS One. 2014 Jun 23;9(6):e99890. doi: 10.1371/journal.pone.0099890. eCollection 2014.


STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.

van Breevoort D, Snijders AP, Hellen N, Weckhuysen S, van Hooren KW, Eikenboom J, Valentijn K, Fernandez-Borja M, Ceulemans B, De Jonghe P, Voorberg J, Hannah M, Carter T, Bierings R.

Blood. 2014 May 15;123(20):3185-94. doi: 10.1182/blood-2013-10-535831. Epub 2014 Apr 3.


Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells.

van Hooren KW, Spijkers LJ, van Breevoort D, Fernandez-Borja M, Bierings R, van Buul JD, Alewijnse AE, Peters SL, Voorberg J.

PLoS One. 2014 Mar 14;9(3):e91346. doi: 10.1371/journal.pone.0091346. eCollection 2014.


Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies.

van Hooren KW, van Breevoort D, Fernandez-Borja M, Meijer AB, Eikenboom J, Bierings R, Voorberg J.

J Thromb Haemost. 2014 Feb;12(2):273-81. doi: 10.1111/jth.12460.


The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.

Bierings R, Hellen N, Kiskin N, Knipe L, Fonseca AV, Patel B, Meli A, Rose M, Hannah MJ, Carter T.

Blood. 2012 Sep 27;120(13):2757-67. Epub 2012 Aug 16.


The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies.

van Agtmaal EL, Bierings R, Dragt BS, Leyen TA, Fernandez-Borja M, Horrevoets AJ, Voorberg J.

PLoS One. 2012;7(6):e38399. doi: 10.1371/journal.pone.0038399. Epub 2012 Jun 8.


The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells.

van Hooren KW, van Agtmaal EL, Fernandez-Borja M, van Mourik JA, Voorberg J, Bierings R.

J Biol Chem. 2012 Jul 13;287(29):24713-20. doi: 10.1074/jbc.M111.321976. Epub 2012 Apr 16.


Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies.

van Breevoort D, van Agtmaal EL, Dragt BS, Gebbinck JK, Dienava-Verdoold I, Kragt A, Bierings R, Horrevoets AJ, Valentijn KM, Eikenboom JC, Fernandez-Borja M, Meijer AB, Voorberg J.

J Proteome Res. 2012 May 4;11(5):2925-36. doi: 10.1021/pr300010r. Epub 2012 Apr 12.


A revised model for the secretion of tPA and cytokines from cultured endothelial cells.

Knipe L, Meli A, Hewlett L, Bierings R, Dempster J, Skehel P, Hannah MJ, Carter T.

Blood. 2010 Sep 23;116(12):2183-91. doi: 10.1182/blood-2010-03-276170. Epub 2010 Jun 10.


Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells.

Rondaij MG, Bierings R, van Agtmaal EL, Gijzen KA, Sellink E, Kragt A, Ferguson SS, Mertens K, Hannah MJ, van Mourik JA, Fernandez-Borja M, Voorberg J.

Blood. 2008 Jul 1;112(1):56-63. doi: 10.1182/blood-2007-07-099309. Epub 2008 Apr 16.


Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.

van den Biggelaar M, Bierings R, Storm G, Voorberg J, Mertens K.

J Thromb Haemost. 2007 Nov;5(11):2235-42.


Efficiency of von Willebrand factor-mediated targeting of interleukin-8 into Weibel-Palade bodies.

Bierings R, van den Biggelaar M, Kragt A, Mertens K, Voorberg J, van Mourik JA.

J Thromb Haemost. 2007 Dec;5(12):2512-9. Epub 2007 Sep 19.


Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network.

Derry WB, Bierings R, van Iersel M, Satkunendran T, Reinke V, Rothman JH.

Cell Death Differ. 2007 Apr;14(4):662-70. Epub 2006 Dec 22.


Dynamics and plasticity of Weibel-Palade bodies in endothelial cells.

Rondaij MG, Bierings R, Kragt A, van Mourik JA, Voorberg J.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):1002-7. Epub 2006 Feb 9. Review.


Dynein-dynactin complex mediates protein kinase A-dependent clustering of Weibel-Palade bodies in endothelial cells.

Rondaij MG, Bierings R, Kragt A, Gijzen KA, Sellink E, van Mourik JA, Fernandez-Borja M, Voorberg J.

Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):49-55. Epub 2005 Oct 20.


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