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Items: 1 to 50 of 94

1.

Association between antibiotic residues, antibiotic resistant bacteria and antibiotic resistance genes in anthropogenic wastewater - An evaluation of clinical influences.

Voigt AM, Zacharias N, Timm C, Wasser F, Sib E, Skutlarek D, Parcina M, Schmithausen RM, Schwartz T, Hembach N, Tiehm A, Stange C, Engelhart S, Bierbaum G, Kistemann T, Exner M, Faerber HA, Schreiber C.

Chemosphere. 2019 Oct 5;241:125032. doi: 10.1016/j.chemosphere.2019.125032. [Epub ahead of print]

PMID:
31622887
2.

The Washing Machine as a Reservoir for Transmission of Extended-Spectrum-Beta-Lactamase (CTX-M-15)-Producing Klebsiella oxytoca ST201 to Newborns.

Schmithausen RM, Sib E, Exner M, Hack S, Rösing C, Ciorba P, Bierbaum G, Savin M, Bloomfield SF, Kaase M, Jacobshagen A, Gemein S, Gebel J, Engelhart S, Exner D.

Appl Environ Microbiol. 2019 Oct 30;85(22). pii: e01435-19. doi: 10.1128/AEM.01435-19. Print 2019 Nov 15.

3.

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus.

Monk IR, Shaikh N, Begg SL, Gajdiss M, Sharkey LKR, Lee JYH, Pidot SJ, Seemann T, Kuiper M, Winnen B, Hvorup R, Collins BM, Bierbaum G, Udagedara SR, Morey JR, Pulyani N, Howden BP, Maher MJ, McDevitt CA, King GF, Stinear TP.

Nat Commun. 2019 Jul 11;10(1):3067. doi: 10.1038/s41467-019-10932-4.

4.

Antibiotic resistant bacteria and resistance genes in biofilms in clinical wastewater networks.

Sib E, Voigt AM, Wilbring G, Schreiber C, Faerber HA, Skutlarek D, Parcina M, Mahn R, Wolf D, Brossart P, Geiser F, Engelhart S, Exner M, Bierbaum G, Schmithausen RM.

Int J Hyg Environ Health. 2019 May;222(4):655-662. doi: 10.1016/j.ijheh.2019.03.006. Epub 2019 Mar 21.

PMID:
30905579
5.

Detection of methicillin-resistant coagulase-negative staphylococci harboring the class A mec complex by MALDI-TOF mass spectrometry.

Schuster D, Josten M, Janssen K, Bodenstein I, Albert C, Schallenberg A, Gajdiss M, Sib E, Szekat C, Kehl K, Parčina M, Hischebeth GTR, Bierbaum G.

Int J Med Microbiol. 2018 Jul;308(5):522-526. doi: 10.1016/j.ijmm.2018.05.001. Epub 2018 May 8.

PMID:
29764754
6.

Dissemination of multi-resistant Gram-negative bacteria into German wastewater and surface waters.

Müller H, Sib E, Gajdiss M, Klanke U, Lenz-Plet F, Barabasch V, Albert C, Schallenberg A, Timm C, Zacharias N, Schmithausen RM, Engelhart S, Exner M, Parcina M, Schreiber C, Bierbaum G.

FEMS Microbiol Ecol. 2018 May 1;94(5). doi: 10.1093/femsec/fiy057.

PMID:
29659796
7.

Rapid monitoring of vancomycin-resistant Enterococcus faecium in hospital departments by repetitive element palindromic polymerase chain reaction.

Froeschen F, Gajdiss M, Uebele J, Meilaender A, Hoerauf A, Exner M, Molitor E, Bierbaum G, Engelhart S, Bekeredjian-Ding I.

J Hosp Infect. 2018 Jun;99(2):208-217. doi: 10.1016/j.jhin.2017.11.017. Epub 2018 Jan 17.

PMID:
29203445
8.

Influence of IS256 on Genome Variability and Formation of Small-Colony Variants in Staphylococcus aureus.

Kleinert F, Kallies R, Hort M, Zweynert A, Szekat C, Nagel M, Bierbaum G.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00144-17. doi: 10.1128/AAC.00144-17. Print 2017 Aug.

9.

Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.

Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I.

PLoS Pathog. 2017 May 25;13(5):e1006387. doi: 10.1371/journal.ppat.1006387. eCollection 2017 May.

10.

Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition.

Schüller A, Matzner D, Lünse CE, Wittmann V, Schumacher C, Unsleber S, Brötz-Oesterhelt H, Mayer C, Bierbaum G, Mayer G.

Chembiochem. 2017 Mar 2;18(5):435-440. doi: 10.1002/cbic.201600491. Epub 2017 Jan 30.

PMID:
28012261
11.

The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus.

Hardt P, Engels I, Rausch M, Gajdiss M, Ulm H, Sass P, Ohlsen K, Sahl HG, Bierbaum G, Schneider T, Grein F.

Int J Med Microbiol. 2017 Jan;307(1):1-10. doi: 10.1016/j.ijmm.2016.12.001. Epub 2016 Dec 12.

PMID:
27989665
12.

Differentiation of Staphylococcus argenteus (formerly: Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape.

Schuster D, Rickmeyer J, Gajdiss M, Thye T, Lorenzen S, Reif M, Josten M, Szekat C, Melo LDR, Schmithausen RM, Liégeois F, Sahl HG, Gonzalez JJ, Nagel M, Bierbaum G.

Int J Med Microbiol. 2017 Jan;307(1):57-63. doi: 10.1016/j.ijmm.2016.11.003. Epub 2016 Nov 30.

PMID:
27931949
13.

Bacterial Histidine Kinases: Overexpression, Purification, and Inhibitor Screen.

Gajdiss M, Türck M, Bierbaum G.

Methods Mol Biol. 2017;1520:247-259. doi: 10.1007/978-1-4939-6634-9_15.

PMID:
27873257
14.

Draft Genome Sequences of Three Northern German Epidemic Staphylococcus aureus (ST247) Strains Containing Multiple Copies of IS256.

Kleinert F, Kallies R, Zweynert A, Bierbaum G.

Genome Announc. 2016 Sep 8;4(5). pii: e00936-16. doi: 10.1128/genomeA.00936-16.

15.

Genome Sequence of Bacillus pumilus Strain Bonn, Isolated from an Anthrax-Like Necrotic Skin Infection Site of a Child.

Grass G, Bierbaum G, Molitor E, Götte N, Antwerpen M.

Genome Announc. 2016 Feb 11;4(1). pii: e01741-15. doi: 10.1128/genomeA.01741-15.

16.

Insights into Structure-Activity Relationships of Bacterial RNA Polymerase Inhibiting Corallopyronin Derivatives.

Schäberle TF, Schmitz A, Zocher G, Schiefer A, Kehraus S, Neu E, Roth M, Vassylyev DG, Stehle T, Bierbaum G, Hoerauf A, Pfarr K, König GM.

J Nat Prod. 2015 Oct 23;78(10):2505-9. doi: 10.1021/acs.jnatprod.5b00175. Epub 2015 Oct 2.

PMID:
26431157
17.

Analysis of Transmission of MRSA and ESBL-E among Pigs and Farm Personnel.

Schmithausen RM, Schulze-Geisthoevel SV, Stemmer F, El-Jade M, Reif M, Hack S, Meilaender A, Montabauer G, Fimmers R, Parcina M, Hoerauf A, Exner M, Petersen B, Bierbaum G, Bekeredjian-Ding I.

PLoS One. 2015 Sep 30;10(9):e0138173. doi: 10.1371/journal.pone.0138173. eCollection 2015.

18.

Eradication of methicillin-resistant Staphylococcus aureus and of Enterobacteriaceae expressing extended-spectrum beta-lactamases on a model pig farm.

Schmithausen RM, Kellner SR, Schulze-Geisthoevel SV, Hack S, Engelhart S, Bodenstein I, Al-Sabti N, Reif M, Fimmers R, Körber-Irrgang B, Harlizius J, Hoerauf A, Exner M, Bierbaum G, Petersen B, Bekeredjian-Ding I.

Appl Environ Microbiol. 2015 Nov;81(21):7633-43. doi: 10.1128/AEM.01713-15. Epub 2015 Sep 4.

19.

Pseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides.

Basi-Chipalu S, Dischinger J, Josten M, Szekat C, Zweynert A, Sahl HG, Bierbaum G.

Appl Environ Microbiol. 2015 May 15;81(10):3419-29. doi: 10.1128/AEM.00299-15. Epub 2015 Mar 13.

20.

Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymes.

Wilmes M, Stockem M, Bierbaum G, Schlag M, Götz F, Tran DQ, Schaal JB, Ouellette AJ, Selsted ME, Sahl HG.

Antibiotics (Basel). 2014;3(4):617-31. doi: 10.3390/antibiotics3040617.

21.

Structural variations of the cell wall precursor lipid II and their influence on binding and activity of the lipoglycopeptide antibiotic oritavancin.

Münch D, Engels I, Müller A, Reder-Christ K, Falkenstein-Paul H, Bierbaum G, Grein F, Bendas G, Sahl HG, Schneider T.

Antimicrob Agents Chemother. 2015 Feb;59(2):772-81. doi: 10.1128/AAC.02663-14. Epub 2014 Nov 17.

22.

Identification of agr-positive methicillin-resistant Staphylococcus aureus harbouring the class A mec complex by MALDI-TOF mass spectrometry.

Josten M, Dischinger J, Szekat C, Reif M, Al-Sabti N, Sahl HG, Parcina M, Bekeredjian-Ding I, Bierbaum G.

Int J Med Microbiol. 2014 Nov;304(8):1018-23. doi: 10.1016/j.ijmm.2014.07.005. Epub 2014 Jul 25.

PMID:
25116838
23.

Generation of a vancomycin-intermediate Staphylococcus aureus (VISA) strain by two amino acid exchanges in VraS.

Berscheid A, François P, Strittmatter A, Gottschalk G, Schrenzel J, Sass P, Bierbaum G.

J Antimicrob Chemother. 2014 Dec;69(12):3190-8. doi: 10.1093/jac/dku297. Epub 2014 Aug 6.

PMID:
25103491
24.

Heterogeneity of host TLR2 stimulation by Staphylocoocus aureus isolates.

Hilmi D, Parcina M, Stollewerk D, Ostrop J, Josten M, Meilaender A, Zaehringer U, Wichelhaus TA, Bierbaum G, Heeg K, Wolz C, Bekeredjian-Ding I.

PLoS One. 2014 May 8;9(5):e96416. doi: 10.1371/journal.pone.0096416. eCollection 2014.

25.

Lantibiotics: promising candidates for future applications in health care.

Dischinger J, Basi Chipalu S, Bierbaum G.

Int J Med Microbiol. 2014 Jan;304(1):51-62. doi: 10.1016/j.ijmm.2013.09.003. Epub 2013 Sep 4. Review.

PMID:
24210177
26.

The search for new anti-infective drugs: untapped resources and strategies.

Bierbaum G, Sahl HG.

Int J Med Microbiol. 2014 Jan;304(1):1-2. doi: 10.1016/j.ijmm.2013.10.003. Epub 2013 Oct 11. No abstract available.

PMID:
24183099
27.

Antibiotic-induced autoactivation of IS256 in Staphylococcus aureus.

Schreiber F, Szekat C, Josten M, Sahl HG, Bierbaum G.

Antimicrob Agents Chemother. 2013 Dec;57(12):6381-4. doi: 10.1128/AAC.01585-13. Epub 2013 Sep 30.

28.

Salimyxins and enhygrolides: antibiotic, sponge-related metabolites from the obligate marine myxobacterium Enhygromyxa salina.

Felder S, Kehraus S, Neu E, Bierbaum G, Schäberle TF, König GM.

Chembiochem. 2013 Jul 22;14(11):1363-71. doi: 10.1002/cbic.201300268. Epub 2013 Jun 21.

PMID:
23794290
29.

Salimabromide: unexpected chemistry from the obligate marine myxobacterium Enhygromxya salina.

Felder S, Dreisigacker S, Kehraus S, Neu E, Bierbaum G, Wright PR, Menche D, Schäberle TF, König GM.

Chemistry. 2013 Jul 8;19(28):9319-24. doi: 10.1002/chem.201301379. Epub 2013 May 22.

PMID:
23703738
30.

Analysis of the matrix-assisted laser desorption ionization-time of flight mass spectrum of Staphylococcus aureus identifies mutations that allow differentiation of the main clonal lineages.

Josten M, Reif M, Szekat C, Al-Sabti N, Roemer T, Sparbier K, Kostrzewa M, Rohde H, Sahl HG, Bierbaum G.

J Clin Microbiol. 2013 Jun;51(6):1809-17. doi: 10.1128/JCM.00518-13. Epub 2013 Apr 3.

31.

Production of capsular polysaccharide does not influence Staphylococcus aureus vancomycin susceptibility.

Jansen A, Szekat C, Schröder W, Wolz C, Goerke C, Lee JC, Türck M, Bierbaum G.

BMC Microbiol. 2013 Mar 22;13:65. doi: 10.1186/1471-2180-13-65.

32.

Human-associated Staphylococcus aureus strains within great ape populations in Central Africa (Gabon).

Nagel M, Dischinger J, Türck M, Verrier D, Oedenkoven M, Ngoubangoye B, Le Flohic G, Drexler JF, Bierbaum G, Gonzalez JP.

Clin Microbiol Infect. 2013 Nov;19(11):1072-7. doi: 10.1111/1469-0691.12119. Epub 2013 Feb 11.

33.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA.

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f. Review.

34.

Diversification of clonal complex 5 methicillin-resistant Staphylococcus aureus strains (Rhine-Hesse clone) within Germany.

Schulte B, Bierbaum G, Pohl K, Goerke C, Wolz C.

J Clin Microbiol. 2013 Jan;51(1):212-6. doi: 10.1128/JCM.01967-12. Epub 2012 Nov 7.

35.

Genome sequence of Staphylococcus aureus VC40, a vancomycin- and daptomycin-resistant strain, to study the genetics of development of resistance to currently applied last-resort antibiotics.

Sass P, Berscheid A, Jansen A, Oedenkoven M, Szekat C, Strittmatter A, Gottschalk G, Bierbaum G.

J Bacteriol. 2012 Apr;194(8):2107-8. doi: 10.1128/JB.06631-11.

36.

Revisiting the genomes of the Staphylococcus aureus strains NCTC 8325 and RN4220.

Berscheid A, Sass P, Weber-Lassalle K, Cheung AL, Bierbaum G.

Int J Med Microbiol. 2012 Mar;302(2):84-7. doi: 10.1016/j.ijmm.2012.01.002. Epub 2012 Mar 12.

PMID:
22417616
37.

Purification and activity testing of the full-length YycFGHI proteins of Staphylococcus aureus.

Türck M, Bierbaum G.

PLoS One. 2012;7(1):e30403. doi: 10.1371/journal.pone.0030403. Epub 2012 Jan 20.

38.

Expression of the lantibiotic mersacidin in Bacillus amyloliquefaciens FZB42.

Herzner AM, Dischinger J, Szekat C, Josten M, Schmitz S, Yakéléba A, Reinartz R, Jansen A, Sahl HG, Piel J, Bierbaum G.

PLoS One. 2011;6(7):e22389. doi: 10.1371/journal.pone.0022389. Epub 2011 Jul 21.

39.

Successful management of an MRSA outbreak in a neonatal intensive care unit.

Heinrich N, Mueller A, Bartmann P, Simon A, Bierbaum G, Engelhart S.

Eur J Clin Microbiol Infect Dis. 2011 Jul;30(7):909-13. doi: 10.1007/s10096-011-1175-4. Epub 2011 Feb 6.

PMID:
21298461
40.

Influence of ciprofloxacin and vancomycin on mutation rate and transposition of IS256 in Staphylococcus aureus.

Nagel M, Reuter T, Jansen A, Szekat C, Bierbaum G.

Int J Med Microbiol. 2011 Mar;301(3):229-36. doi: 10.1016/j.ijmm.2010.08.021. Epub 2010 Nov 5.

PMID:
21115395
41.

Marine myxobacteria as a source of antibiotics--comparison of physiology, polyketide-type genes and antibiotic production of three new isolates of Enhygromyxa salina.

Schäberle TF, Goralski E, Neu E, Erol O, Hölzl G, Dörmann P, Bierbaum G, König GM.

Mar Drugs. 2010 Sep 3;8(9):2466-79. doi: 10.3390/md8092466.

42.

Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13.

Dischinger J, Josten M, Szekat C, Sahl HG, Bierbaum G.

PLoS One. 2009 Aug 26;4(8):e6788. doi: 10.1371/journal.pone.0006788.

43.

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates.

Marklein G, Josten M, Klanke U, Müller E, Horré R, Maier T, Wenzel T, Kostrzewa M, Bierbaum G, Hoerauf A, Sahl HG.

J Clin Microbiol. 2009 Sep;47(9):2912-7. doi: 10.1128/JCM.00389-09. Epub 2009 Jul 1.

44.

Dissecting structural and functional diversity of the lantibiotic mersacidin.

Appleyard AN, Choi S, Read DM, Lightfoot A, Boakes S, Hoffmann A, Chopra I, Bierbaum G, Rudd BA, Dawson MJ, Cortes J.

Chem Biol. 2009 May 29;16(5):490-8. doi: 10.1016/j.chembiol.2009.03.011.

45.

Lantibiotics: mode of action, biosynthesis and bioengineering.

Bierbaum G, Sahl HG.

Curr Pharm Biotechnol. 2009 Jan;10(1):2-18. Review.

PMID:
19149587
46.

Native graS mutation supports the susceptibility of Staphylococcus aureus strain SG511 to antimicrobial peptides.

Sass P, Bierbaum G.

Int J Med Microbiol. 2009 Jun;299(5):313-22. doi: 10.1016/j.ijmm.2008.10.005. Epub 2009 Jan 9.

PMID:
19138560
47.

The lantibiotic mersacidin is a strong inducer of the cell wall stress response of Staphylococcus aureus.

Sass P, Jansen A, Szekat C, Sass V, Sahl HG, Bierbaum G.

BMC Microbiol. 2008 Oct 23;8:186. doi: 10.1186/1471-2180-8-186.

48.

Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge.

Sass V, Pag U, Tossi A, Bierbaum G, Sahl HG.

Int J Med Microbiol. 2008 Oct;298(7-8):619-33. doi: 10.1016/j.ijmm.2008.01.011. Epub 2008 May 1.

PMID:
18455476
49.

Detection of astrovirus in premature infants with necrotizing enterocolitis.

Bagci S, Eis-Hübinger AM, Franz AR, Bierbaum G, Heep A, Schildgen O, Bartmann P, Kupfer B, Mueller A.

Pediatr Infect Dis J. 2008 Apr;27(4):347-50. doi: 10.1097/INF.0b013e318162a17a.

PMID:
18316982
50.

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