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Items: 1 to 50 of 138

1.

Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host.

Schmidt F, Keele BF, Del Prete GQ, Voronin D, Fennessey CM, Soll S, Kane M, Raymond A, Gifford RJ, KewalRamani V, Lifson JD, Bieniasz PD, Hatziioannou T.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10504-10509. doi: 10.1073/pnas.1818059116. Epub 2019 May 2.

PMID:
31048506
2.

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.

O'Brien SP, Swanstrom AE, Pegu A, Ko SY, Immonen TT, Del Prete GQ, Fennessey CM, Gorman J, Foulds KE, Schmidt SD, Doria-Rose N, Williamson C, Hatziioannou T, Bieniasz PD, Li H, Shaw GM, Mascola JR, Koup RA, Kwong PD, Lifson JD, Roederer M, Keele BF.

PLoS Pathog. 2019 Apr 3;15(4):e1007632. doi: 10.1371/journal.ppat.1007632. eCollection 2019 Apr.

3.

The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression.

Kueck T, Cassella E, Holler J, Kim B, Bieniasz PD.

Elife. 2018 Aug 22;7. pii: e38867. doi: 10.7554/eLife.38867.

4.

Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2.

Kane M, Rebensburg SV, Takata MA, Zang TM, Yamashita M, Kvaratskhelia M, Bieniasz PD.

Elife. 2018 Aug 7;7. pii: e35738. doi: 10.7554/eLife.35738.

5.

CLIP-related methodologies and their application to retrovirology.

Bieniasz PD, Kutluay SB.

Retrovirology. 2018 May 2;15(1):35. doi: 10.1186/s12977-018-0417-2. Review.

6.

Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L.

Blanco-Melo D, Gifford RJ, Bieniasz PD.

Retrovirology. 2018 May 2;15(1):34. doi: 10.1186/s12977-018-0416-3.

7.

Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.

Feng J, Wickenhagen A, Turnbull ML, Rezelj VV, Kreher F, Tilston-Lunel NL, Slack GS, Brennan B, Koudriakova E, Shaw AE, Rihn SJ, Rice CM, Bieniasz PD, Elliott RM, Shi X, Wilson SJ.

J Virol. 2018 Jun 13;92(13). pii: e02140-17. doi: 10.1128/JVI.02140-17. Print 2018 Jul 1.

8.

Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication.

Takata MA, Soll SJ, Emery A, Blanco-Melo D, Swanstrom R, Bieniasz PD.

PLoS Pathog. 2018 Jan 29;14(1):e1006824. doi: 10.1371/journal.ppat.1006824. eCollection 2018 Jan.

9.

A multimodal antiretroviral protein.

Bieniasz PD.

Nat Microbiol. 2018 Feb;3(2):122-123. doi: 10.1038/s41564-017-0104-4. No abstract available.

PMID:
29358682
10.

APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.

Bohn JA, Thummar K, York A, Raymond A, Brown WC, Bieniasz PD, Hatziioannou T, Smith JL.

Nat Commun. 2017 Oct 18;8(1):1021. doi: 10.1038/s41467-017-01309-6.

11.

CG dinucleotide suppression enables antiviral defence targeting non-self RNA.

Takata MA, Gon├žalves-Carneiro D, Zang TM, Soll SJ, York A, Blanco-Melo D, Bieniasz PD.

Nature. 2017 Oct 5;550(7674):124-127. doi: 10.1038/nature24039. Epub 2017 Sep 27.

PMID:
28953888
12.

A single gp120 residue can affect HIV-1 tropism in macaques.

Del Prete GQ, Keele BF, Fode J, Thummar K, Swanstrom AE, Rodriguez A, Raymond A, Estes JD, LaBranche CC, Montefiori DC, KewalRamani VN, Lifson JD, Bieniasz PD, Hatziioannou T.

PLoS Pathog. 2017 Sep 25;13(9):e1006572. doi: 10.1371/journal.ppat.1006572. eCollection 2017 Sep.

13.

Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors.

Blanco-Melo D, Gifford RJ, Bieniasz PD.

Elife. 2017 Apr 11;6. pii: e22519. doi: 10.7554/eLife.22519.

14.

Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis.

Liberatore RA, Mastrocola EJ, Powell C, Bieniasz PD.

J Virol. 2017 May 26;91(12). pii: e02286-16. doi: 10.1128/JVI.02286-16. Print 2017 Jun 15.

15.

Identification of Interferon-Stimulated Genes with Antiretroviral Activity.

Kane M, Zang TM, Rihn SJ, Zhang F, Kueck T, Alim M, Schoggins J, Rice CM, Wilson SJ, Bieniasz PD.

Cell Host Microbe. 2016 Sep 14;20(3):392-405. doi: 10.1016/j.chom.2016.08.005.

16.

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis.

Kessl JJ, Kutluay SB, Townsend D, Rebensburg S, Slaughter A, Larue RC, Shkriabai N, Bakouche N, Fuchs JR, Bieniasz PD, Kvaratskhelia M.

Cell. 2016 Aug 25;166(5):1257-1268.e12. doi: 10.1016/j.cell.2016.07.044.

17.

The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid.

York A, Kutluay SB, Errando M, Bieniasz PD.

PLoS Pathog. 2016 Aug 19;12(8):e1005833. doi: 10.1371/journal.ppat.1005833. eCollection 2016 Aug.

18.

Origins and Evolution of tetherin, an Orphan Antiviral Gene.

Blanco-Melo D, Venkatesh S, Bieniasz PD.

Cell Host Microbe. 2016 Aug 10;20(2):189-201. doi: 10.1016/j.chom.2016.06.007. Epub 2016 Jul 14.

19.

Analysis of the human immunodeficiency virus-1 RNA packageome.

Eckwahl MJ, Arnion H, Kharytonchyk S, Zang T, Bieniasz PD, Telesnitsky A, Wolin SL.

RNA. 2016 Aug;22(8):1228-38. doi: 10.1261/rna.057299.116. Epub 2016 May 31.

20.

Analysis of HIV-1 Gag-RNA Interactions in Cells and Virions by CLIP-seq.

Kutluay SB, Bieniasz PD.

Methods Mol Biol. 2016;1354:119-31. doi: 10.1007/978-1-4939-3046-3_8.

21.

Correction for Bitzegeio et al., Adaptation to the Interferon-Induced Antiviral State by Human and Simian Immunodeficiency Viruses.

Bitzegeio J, Sampias M, Bieniasz PD, Hatziioannou T.

J Virol. 2015 Oct;89(19):10133. doi: 10.1128/JVI.01711-15. No abstract available.

22.

Single-Cell and Single-Cycle Analysis of HIV-1 Replication.

Holmes M, Zhang F, Bieniasz PD.

PLoS Pathog. 2015 Jun 18;11(6):e1004961. doi: 10.1371/journal.ppat.1004961. eCollection 2015 Jun.

23.

A serpin shapes the extracellular environment to prevent influenza A virus maturation.

Dittmann M, Hoffmann HH, Scull MA, Gilmore RH, Bell KL, Ciancanelli M, Wilson SJ, Crotta S, Yu Y, Flatley B, Xiao JW, Casanova JL, Wack A, Bieniasz PD, Rice CM.

Cell. 2015 Feb 12;160(4):631-643. doi: 10.1016/j.cell.2015.01.040.

24.

Global changes in the RNA binding specificity of HIV-1 gag regulate virion genesis.

Kutluay SB, Zang T, Blanco-Melo D, Powell C, Jannain D, Errando M, Bieniasz PD.

Cell. 2014 Nov 20;159(5):1096-1109. doi: 10.1016/j.cell.2014.09.057. Epub 2014 Nov 6.

25.

Uneven genetic robustness of HIV-1 integrase.

Rihn SJ, Hughes J, Wilson SJ, Bieniasz PD.

J Virol. 2015 Jan;89(1):552-67. doi: 10.1128/JVI.02451-14. Epub 2014 Oct 22.

26.

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins.

Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM, Chertova E, Smedley J, LaBranche CC, Montefiori DC, Burton DR, Shaw GM, Markowitz M, Piatak M Jr, KewalRamani VN, Bieniasz PD, Lifson JD, Hatziioannou T.

Cell Host Microbe. 2014 Sep 10;16(3):412-8. doi: 10.1016/j.chom.2014.08.003.

27.

Temporal and spatial organization of ESCRT protein recruitment during HIV-1 budding.

Bleck M, Itano MS, Johnson DS, Thomas VK, North AJ, Bieniasz PD, Simon SM.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12211-6. doi: 10.1073/pnas.1321655111. Epub 2014 Aug 6.

28.

HIV-1-induced AIDS in monkeys.

Hatziioannou T, Del Prete GQ, Keele BF, Estes JD, McNatt MW, Bitzegeio J, Raymond A, Rodriguez A, Schmidt F, Mac Trubey C, Smedley J, Piatak M Jr, KewalRamani VN, Lifson JD, Bieniasz PD.

Science. 2014 Jun 20;344(6190):1401-5. doi: 10.1126/science.1250761.

29.

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.

Li SX, Barrett BS, Heilman KJ, Messer RJ, Liberatore RA, Bieniasz PD, Kassiotis G, Hasenkrug KJ, Santiago ML.

J Immunol. 2014 Jul 1;193(1):306-16. doi: 10.4049/jimmunol.1400490. Epub 2014 May 28.

30.

Host and viral determinants of Mx2 antiretroviral activity.

Busnadiego I, Kane M, Rihn SJ, Preugschas HF, Hughes J, Blanco-Melo D, Strouvelle VP, Zang TM, Willett BJ, Boutell C, Bieniasz PD, Wilson SJ.

J Virol. 2014 Jul;88(14):7738-52. doi: 10.1128/JVI.00214-14. Epub 2014 Apr 23.

31.

MX2 is an interferon-induced inhibitor of HIV-1 infection.

Kane M, Yadav SS, Bitzegeio J, Kutluay SB, Zang T, Wilson SJ, Schoggins JW, Rice CM, Yamashita M, Hatziioannou T, Bieniasz PD.

Nature. 2013 Oct 24;502(7472):563-6. doi: 10.1038/nature12653. Epub 2013 Oct 13.

32.

Assisted evolution enables HIV-1 to overcome a high TRIM5╬▒-imposed genetic barrier to rhesus macaque tropism.

Soll SJ, Wilson SJ, Kutluay SB, Hatziioannou T, Bieniasz PD.

PLoS Pathog. 2013;9(9):e1003667. doi: 10.1371/journal.ppat.1003667. Epub 2013 Sep 26.

33.

Mechanism of HIV-1 virion entrapment by tetherin.

Venkatesh S, Bieniasz PD.

PLoS Pathog. 2013;9(7):e1003483. doi: 10.1371/journal.ppat.1003483. Epub 2013 Jul 18.

34.

SAMHD1-dependent retroviral control and escape in mice.

Rehwinkel J, Maelfait J, Bridgeman A, Rigby R, Hayward B, Liberatore RA, Bieniasz PD, Towers GJ, Moita LF, Crow YJ, Bonthron DT, Reis e Sousa C.

EMBO J. 2013 Sep 11;32(18):2454-62. doi: 10.1038/emboj.2013.163. Epub 2013 Jul 19.

35.

Extreme genetic fragility of the HIV-1 capsid.

Rihn SJ, Wilson SJ, Loman NJ, Alim M, Bakker SE, Bhella D, Gifford RJ, Rixon FJ, Bieniasz PD.

PLoS Pathog. 2013;9(6):e1003461. doi: 10.1371/journal.ppat.1003461. Epub 2013 Jun 20.

36.

Vpu binds directly to tetherin and displaces it from nascent virions.

McNatt MW, Zang T, Bieniasz PD.

PLoS Pathog. 2013;9(4):e1003299. doi: 10.1371/journal.ppat.1003299. Epub 2013 Apr 25.

37.

Fates of retroviral core components during unrestricted and TRIM5-restricted infection.

Kutluay SB, Perez-Caballero D, Bieniasz PD.

PLoS Pathog. 2013 Mar;9(3):e1003214. doi: 10.1371/journal.ppat.1003214. Epub 2013 Mar 7.

38.

Adaptation to the interferon-induced antiviral state by human and simian immunodeficiency viruses.

Bitzegeio J, Sampias M, Bieniasz PD, Hatziioannou T.

J Virol. 2013 Mar;87(6):3549-60. doi: 10.1128/JVI.03219-12. Epub 2013 Jan 16. Erratum in: J Virol. 2015 Oct;89(19):10133.

39.

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, Mouquet H, Spatz LA, Diskin R, Abadir A, Zang T, Dorner M, Billerbeck E, Labitt RN, Gaebler C, Marcovecchio P, Incesu RB, Eisenreich TR, Bieniasz PD, Seaman MS, Bjorkman PJ, Ravetch JV, Ploss A, Nussenzweig MC.

Nature. 2012 Dec 6;492(7427):118-22. doi: 10.1038/nature11604. Epub 2012 Oct 24.

40.

Inhibition of HIV-1 particle assembly by 2',3'-cyclic-nucleotide 3'-phosphodiesterase.

Wilson SJ, Schoggins JW, Zang T, Kutluay SB, Jouvenet N, Alim MA, Bitzegeio J, Rice CM, Bieniasz PD.

Cell Host Microbe. 2012 Oct 18;12(4):585-97. doi: 10.1016/j.chom.2012.08.012.

41.

Intrinsic cellular defenses against human immunodeficiency viruses.

Blanco-Melo D, Venkatesh S, Bieniasz PD.

Immunity. 2012 Sep 21;37(3):399-411. doi: 10.1016/j.immuni.2012.08.013.

42.

A facile quantitative assay for viral particle genesis reveals cooperativity in virion assembly and saturation of an antiviral protein.

Yadav SS, Wilson SJ, Bieniasz PD.

Virology. 2012 Aug 1;429(2):155-62. doi: 10.1016/j.virol.2012.04.008. Epub 2012 May 8.

43.

HIV Restriction Factors and Mechanisms of Evasion.

Malim MH, Bieniasz PD.

Cold Spring Harb Perspect Med. 2012 May;2(5):a006940. doi: 10.1101/cshperspect.a006940. Review.

44.

An overview of intracellular interactions between immunodeficiency viruses and their hosts.

Bieniasz PD.

AIDS. 2012 Jun 19;26(10):1243-54. doi: 10.1097/QAD.0b013e328353bd04. Review.

PMID:
22472854
45.

Antiretroviral restriction factors.

Hatziioannou T, Bieniasz PD.

Curr Opin Virol. 2011 Dec;1(6):526-32. doi: 10.1016/j.coviro.2011.10.007. Review.

46.

Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo.

Liberatore RA, Bieniasz PD.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18097-101. doi: 10.1073/pnas.1113694108. Epub 2011 Oct 24.

47.

Sensing retroviruses.

Liberatore RA, Bieniasz PD.

Immunity. 2011 Jul 22;35(1):8-10. doi: 10.1016/j.immuni.2011.07.004.

48.

Visualizing HIV-1 assembly.

Jouvenet N, Simon SM, Bieniasz PD.

J Mol Biol. 2011 Jul 22;410(4):501-11. doi: 10.1016/j.jmb.2011.04.062. Review.

49.

Clathrin facilitates the morphogenesis of retrovirus particles.

Zhang F, Zang T, Wilson SJ, Johnson MC, Bieniasz PD.

PLoS Pathog. 2011 Jun;7(6):e1002119. doi: 10.1371/journal.ppat.1002119. Epub 2011 Jun 30.

50.

SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release.

Zhang F, Landford WN, Ng M, McNatt MW, Bieniasz PD, Hatziioannou T.

PLoS Pathog. 2011 May;7(5):e1002039. doi: 10.1371/journal.ppat.1002039. Epub 2011 May 19.

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