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Items: 5


Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis.

Bien CM, Espenshade PJ.

Eukaryot Cell. 2010 Mar;9(3):352-9. doi: 10.1128/EC.00358-09. Epub 2010 Jan 29. Review.


Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs.

Bien CM, Chang YC, Nes WD, Kwon-Chung KJ, Espenshade PJ.

Mol Microbiol. 2009 Nov;74(3):672-90. doi: 10.1111/j.1365-2958.2009.06895.x. Epub 2009 Oct 8.


Cobalt chloride, a hypoxia-mimicking agent, targets sterol synthesis in the pathogenic fungus Cryptococcus neoformans.

Lee H, Bien CM, Hughes AL, Espenshade PJ, Kwon-Chung KJ, Chang YC.

Mol Microbiol. 2007 Aug;65(4):1018-33. Epub 2007 Jul 21.


4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.

Hughes AL, Lee CY, Bien CM, Espenshade PJ.

J Biol Chem. 2007 Aug 17;282(33):24388-96. Epub 2007 Jun 26.


Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans.

Chang YC, Bien CM, Lee H, Espenshade PJ, Kwon-Chung KJ.

Mol Microbiol. 2007 May;64(3):614-29.

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