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Items: 28

1.

c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer.

Caggiano C, Pieraccioli M, Panzeri V, Sette C, Bielli P.

Nucleic Acids Res. 2019 May 8. pii: gkz344. doi: 10.1093/nar/gkz344. [Epub ahead of print]

PMID:
31066450
2.

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation.

Naro C, Pellegrini L, Jolly A, Farini D, Cesari E, Bielli P, de la Grange P, Sette C.

Cell Rep. 2019 Mar 12;26(11):2929-2941.e5. doi: 10.1016/j.celrep.2019.02.058.

3.

The emerging role of PTBP1 in human cancer: novel prognostic factor in non-muscle invasive bladder cancer.

Bielli P, Di Stasi SM, Sette C.

Transl Androl Urol. 2018 Dec;7(Suppl 6):S765-S767. doi: 10.21037/tau.2018.12.01. No abstract available.

4.

The Splicing Factor PTBP1 Promotes Expression of Oncogenic Splice Variants and Predicts Poor Prognosis in Patients with Non-muscle-Invasive Bladder Cancer.

Bielli P, Panzeri V, Lattanzio R, Mutascio S, Pieraccioli M, Volpe E, Pagliarulo V, Piantelli M, Giannantoni A, Di Stasi SM, Sette C.

Clin Cancer Res. 2018 Nov 1;24(21):5422-5432. doi: 10.1158/1078-0432.CCR-17-3850. Epub 2018 Jul 16.

PMID:
30012566
5.

DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.

Pascarella A, Ferrandino G, Credendino SC, Moccia C, D'Angelo F, Miranda B, D'Ambrosio C, Bielli P, Spadaro O, Ceccarelli M, Scaloni A, Sette C, De Felice M, De Vita G, Amendola E.

Sci Rep. 2018 May 17;8(1):7794. doi: 10.1038/s41598-018-26093-1.

6.

Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells.

Passacantilli I, Panzeri V, Bielli P, Farini D, Pilozzi E, Fave GD, Capurso G, Sette C.

Cell Death Dis. 2017 Nov 9;8(11):e3168. doi: 10.1038/cddis.2017.562.

7.
8.

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, De la Grange P, Sette C.

Dev Cell. 2017 Apr 10;41(1):82-93.e4. doi: 10.1016/j.devcel.2017.03.003. Epub 2017 Mar 30.

9.

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

Nazio F, Carinci M, Valacca C, Bielli P, Strappazzon F, Antonioli M, Ciccosanti F, Rodolfo C, Campello S, Fimia GM, Sette C, Bonaldo P, Cecconi F.

J Cell Biol. 2016 Dec 19;215(6):841-856. Epub 2016 Dec 8.

10.

Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing.

La Rosa P, Bielli P, Compagnucci C, Cesari E, Volpe E, Farioli Vecchioli S, Sette C.

Elife. 2016 Nov 15;5. pii: e20750. doi: 10.7554/eLife.20750.

11.

MIR retroposon exonization promotes evolutionary variability and generates species-specific expression of IGF-1 splice variants.

Annibalini G, Bielli P, De Santi M, Agostini D, Guescini M, Sisti D, Contarelli S, Brandi G, Villarini A, Stocchi V, Sette C, Barbieri E.

Biochim Biophys Acta. 2016 May;1859(5):757-68. doi: 10.1016/j.bbagrm.2016.03.014. Epub 2016 Apr 19.

PMID:
27048986
12.

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells.

Calabretta S, Bielli P, Passacantilli I, Pilozzi E, Fendrich V, Capurso G, Fave GD, Sette C.

Oncogene. 2016 Apr 21;35(16):2031-9. doi: 10.1038/onc.2015.270. Epub 2015 Aug 3.

13.

The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability.

Naro C, Bielli P, Pagliarini V, Sette C.

Front Genet. 2015 Apr 15;6:142. doi: 10.3389/fgene.2015.00142. eCollection 2015.

14.

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.

Bielli P, Bordi M, Di Biasio V, Sette C.

Nucleic Acids Res. 2014 Oct 29;42(19):12070-81. doi: 10.1093/nar/gku922. Epub 2014 Oct 7.

15.

The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.

Bielli P, Busà R, Di Stasi SM, Munoz MJ, Botti F, Kornblihtt AR, Sette C.

EMBO Rep. 2014 Apr;15(4):419-27. doi: 10.1002/embr.201338241. Epub 2014 Feb 10.

16.

The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells.

Cappellari M, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Saarikettu J, Silvennoinen O, Sette C.

Oncogene. 2014 Jul 17;33(29):3794-802. doi: 10.1038/onc.2013.360. Epub 2013 Sep 2.

PMID:
23995791
17.

ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.

Fausti F, Di Agostino S, Cioce M, Bielli P, Sette C, Pandolfi PP, Oren M, Sudol M, Strano S, Blandino G.

Cell Death Differ. 2013 Nov;20(11):1498-509. doi: 10.1038/cdd.2013.101. Epub 2013 Aug 9.

18.

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

Nazio F, Strappazzon F, Antonioli M, Bielli P, Cianfanelli V, Bordi M, Gretzmeier C, Dengjel J, Piacentini M, Fimia GM, Cecconi F.

Nat Cell Biol. 2013 Apr;15(4):406-16. doi: 10.1038/ncb2708. Epub 2013 Mar 24.

PMID:
23524951
19.

The RNA-binding protein Sam68 is a multifunctional player in human cancer.

Bielli P, Busà R, Paronetto MP, Sette C.

Endocr Relat Cancer. 2011 Jul 1;18(4):R91-R102. doi: 10.1530/ERC-11-0041. Print 2011 Aug. Review.

PMID:
21565971
20.

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.

Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C.

EMBO J. 2010 Apr 7;29(7):1235-47. doi: 10.1038/emboj.2010.19. Epub 2010 Feb 25.

21.

Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.

Bianchini A, Loiarro M, Bielli P, Busà R, Paronetto MP, Loreni F, Geremia R, Sette C.

Carcinogenesis. 2008 Dec;29(12):2279-88. doi: 10.1093/carcin/bgn221. Epub 2008 Sep 22.

PMID:
18809972
22.

Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain.

Casavola EC, Catucci A, Bielli P, Di Pentima A, Porcu G, Pennestri M, Cicero DO, Ragnini-Wilson A.

Mol Microbiol. 2008 Mar;67(5):1051-66. doi: 10.1111/j.1365-2958.2008.06106.x. Epub 2008 Jan 23.

23.

GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.

Bielli P, Casavola EC, Biroccio A, Urbani A, Ragnini-Wilson A.

Mol Microbiol. 2006 Mar;59(5):1576-90.

24.

Assignment of the 1H, 13C and 15N resonances of Mlc1p from Saccharomices cerevisiae.

Melino S, Pennestri M, Santoprete A, Bielli P, Paci M, Ragnini-Wilson A, Cicero DO.

J Biomol NMR. 2005 Apr;31(4):367-8. No abstract available.

PMID:
15929007
25.

Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.

Wagner W, Bielli P, Wacha S, Ragnini-Wilson A.

EMBO J. 2002 Dec 2;21(23):6397-408.

26.

Structure to function relationships in ceruloplasmin: a 'moonlighting' protein.

Bielli P, Calabrese L.

Cell Mol Life Sci. 2002 Sep;59(9):1413-27. Review.

PMID:
12440766
27.
28.

Release of highly active Fet3 from membranes of the yeast Pichia pastoris by limited proteolysis.

Bonaccorsi di Patti MC, Bellenchi GC, Bielli P, Calabrese L.

Arch Biochem Biophys. 1999 Dec 15;372(2):295-9.

PMID:
10600167

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