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Items: 45


Quantification of microaerobic growth of Geobacter sulfurreducens.

Engel CEA, Vorländer D, Biedendieck R, Krull R, Dohnt K.

PLoS One. 2020 Jan 16;15(1):e0215341. doi: 10.1371/journal.pone.0215341. eCollection 2020.


Complete Genome Sequence of Raoultella electrica 1GB (DSM 102253T), Isolated from Anodic Biofilms of a Glucose-Fed Microbial Fuel Cell.

Thiel S, Bunk B, Spröer C, Overmann J, Jahn D, Biedendieck R.

Microbiol Resour Announc. 2019 Oct 24;8(43). pii: e00800-19. doi: 10.1128/MRA.00800-19.


Spray-Dried Hierarchical Aggregates of Iron Oxide Nanoparticles and Their Functionalization for Downstream Processing in Biotechnology.

Kleinfeldt L, Gädke J, Biedendieck R, Krull R, Garnweitner G.

ACS Omega. 2019 Sep 26;4(15):16300-16308. doi: 10.1021/acsomega.9b01549. eCollection 2019 Oct 8.


Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability.

Mayer J, Pippel J, Günther G, Müller C, Lauermann A, Knuuti T, Blankenfeldt W, Jahn D, Biedendieck R.

Appl Microbiol Biotechnol. 2019 Sep;103(18):7537-7552. doi: 10.1007/s00253-019-09977-8. Epub 2019 Jun 21.


Evolutionary model for the unequal segregation of high copy plasmids.

Münch K, Münch R, Biedendieck R, Jahn D, Müller J.

PLoS Comput Biol. 2019 Mar 5;15(3):e1006724. doi: 10.1371/journal.pcbi.1006724. eCollection 2019 Mar.


Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production.

Hofmann JD, Otto A, Berges M, Biedendieck R, Michel AM, Becher D, Jahn D, Neumann-Schaal M.

Front Microbiol. 2018 Aug 21;9:1970. doi: 10.3389/fmicb.2018.01970. eCollection 2018.


Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from nonmodel bacteria.

Moore SJ, MacDonald JT, Wienecke S, Ishwarbhai A, Tsipa A, Aw R, Kylilis N, Bell DJ, McClymont DW, Jensen K, Polizzi KM, Biedendieck R, Freemont PS.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4340-E4349. doi: 10.1073/pnas.1715806115. Epub 2018 Apr 17.


Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy.

Blaženović I, Kind T, Torbašinović H, Obrenović S, Mehta SS, Tsugawa H, Wermuth T, Schauer N, Jahn M, Biedendieck R, Jahn D, Fiehn O.

J Cheminform. 2017 May 25;9(1):32. doi: 10.1186/s13321-017-0219-x.


Selective manipulation of superparamagnetic nanoparticles for product purification and microfluidic diagnostics.

Gädke J, Thies JW, Kleinfeldt L, Schulze T, Biedendieck R, Rustenbeck I, Garnweitner G, Krull R, Dietzel A.

Eur J Pharm Biopharm. 2018 May;126:67-74. doi: 10.1016/j.ejpb.2017.09.008. Epub 2017 Sep 13. Review.


Mini review: Recombinant production of tailored bio-pharmaceuticals in different Bacillus strains and future perspectives.

Lakowitz A, Godard T, Biedendieck R, Krull R.

Eur J Pharm Biopharm. 2018 May;126:27-39. doi: 10.1016/j.ejpb.2017.06.008. Epub 2017 Jun 9. Review.


Recombinant production of the antibody fragment D1.3 scFv with different Bacillus strains.

Lakowitz A, Krull R, Biedendieck R.

Microb Cell Fact. 2017 Jan 23;16(1):14. doi: 10.1186/s12934-017-0625-9.


In situ affinity purification of his-tagged protein A from Bacillus megaterium cultivation using recyclable superparamagnetic iron oxide nanoparticles.

Gädke J, Kleinfeldt L, Schubert C, Rohde M, Biedendieck R, Garnweitner G, Krull R.

J Biotechnol. 2017 Jan 20;242:55-63. doi: 10.1016/j.jbiotec.2016.11.018. Epub 2016 Nov 23.


A Bacillus megaterium System for the Production of Recombinant Proteins and Protein Complexes.

Biedendieck R.

Adv Exp Med Biol. 2016;896:97-113. doi: 10.1007/978-3-319-27216-0_7. Review.


Complete genome sequence of the bioleaching bacterium Leptospirillum sp. group II strain CF-1.

Ferrer A, Bunk B, Spröer C, Biedendieck R, Valdés N, Jahn M, Jahn D, Orellana O, Levicán G.

J Biotechnol. 2016 Mar 20;222:21-2. doi: 10.1016/j.jbiotec.2016.02.008. Epub 2016 Feb 4.


Functionalized PHB granules provide the basis for the efficient side-chain cleavage of cholesterol and analogs in recombinant Bacillus megaterium.

Gerber A, Kleser M, Biedendieck R, Bernhardt R, Hannemann F.

Microb Cell Fact. 2015 Jul 29;14:107. doi: 10.1186/s12934-015-0300-y.


Impact of rare codons and the functional coproduction of rate-limiting tRNAs on recombinant protein production in Bacillus megaterium.

Finger C, Gamer M, Klunkelfuß S, Bunk B, Biedendieck R.

Appl Microbiol Biotechnol. 2015 Nov;99(21):8999-9010. doi: 10.1007/s00253-015-6744-5. Epub 2015 Jul 3.


Polar Fixation of Plasmids during Recombinant Protein Production in Bacillus megaterium Results in Population Heterogeneity.

Münch KM, Müller J, Wienecke S, Bergmann S, Heyber S, Biedendieck R, Münch R, Jahn D.

Appl Environ Microbiol. 2015 Sep 1;81(17):5976-86. doi: 10.1128/AEM.00807-15. Epub 2015 Jun 26.


Towards a cell factory for vitamin B12 production in Bacillus megaterium: bypassing of the cobalamin riboswitch control elements.

Moore SJ, Mayer MJ, Biedendieck R, Deery E, Warren MJ.

N Biotechnol. 2014 Dec 25;31(6):553-61. doi: 10.1016/j.nbt.2014.03.003. Epub 2014 Mar 20.


Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12).

Moore SJ, Lawrence AD, Biedendieck R, Deery E, Frank S, Howard MJ, Rigby SE, Warren MJ.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14906-11. doi: 10.1073/pnas.1308098110. Epub 2013 Aug 6.


Bacillus megaterium has both a functional BluB protein required for DMB synthesis and a related flavoprotein that forms a stable radical species.

Collins HF, Biedendieck R, Leech HK, Gray M, Escalante-Semerena JC, McLean KJ, Munro AW, Rigby SE, Warren MJ, Lawrence AD.

PLoS One. 2013;8(2):e55708. doi: 10.1371/journal.pone.0055708. Epub 2013 Feb 14.


Systems metabolic engineering of xylose-utilizing Corynebacterium glutamicum for production of 1,5-diaminopentane.

Buschke N, Becker J, Schäfer R, Kiefer P, Biedendieck R, Wittmann C.

Biotechnol J. 2013 May;8(5):557-70. doi: 10.1002/biot.201200367. Epub 2013 Apr 16.


High yield production of extracellular recombinant levansucrase by Bacillus megaterium.

Korneli C, Biedendieck R, David F, Jahn D, Wittmann C.

Appl Microbiol Biotechnol. 2013 Apr;97(8):3343-53. doi: 10.1007/s00253-012-4567-1. Epub 2012 Nov 23.


Characterization of the enzyme CbiH60 involved in anaerobic ring contraction of the cobalamin (vitamin B12) biosynthetic pathway.

Moore SJ, Biedendieck R, Lawrence AD, Deery E, Howard MJ, Rigby SE, Warren MJ.

J Biol Chem. 2013 Jan 4;288(1):297-305. doi: 10.1074/jbc.M112.422535. Epub 2012 Nov 15.


TLM-Tracker: software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies.

Klein J, Leupold S, Biegler I, Biedendieck R, Münch R, Jahn D.

Bioinformatics. 2012 Sep 1;28(17):2276-7. doi: 10.1093/bioinformatics/bts424. Epub 2012 Jul 5.


Getting the big beast to work--systems biotechnology of Bacillus megaterium for novel high-value proteins.

Korneli C, David F, Biedendieck R, Jahn D, Wittmann C.

J Biotechnol. 2013 Jan 20;163(2):87-96. doi: 10.1016/j.jbiotec.2012.06.018. Epub 2012 Jun 28. Review.


Systems biology of recombinant protein production using Bacillus megaterium.

Biedendieck R, Borgmeier C, Bunk B, Stammen S, Scherling C, Meinhardt F, Wittmann C, Jahn D.

Methods Enzymol. 2011;500:165-95. doi: 10.1016/B978-0-12-385118-5.00010-4.


Transcriptome profiling of degU expression reveals unexpected regulatory patterns in Bacillus megaterium and discloses new targets for optimizing expression.

Borgmeier C, Biedendieck R, Hoffmann K, Jahn D, Meinhardt F.

Appl Microbiol Biotechnol. 2011 Nov;92(3):583-96. doi: 10.1007/s00253-011-3575-x. Epub 2011 Sep 21. Erratum in: Appl Microbiol Biotechnol. 2011 Dec;92(6):1315-6.


Genome sequences of the biotechnologically important Bacillus megaterium strains QM B1551 and DSM319.

Eppinger M, Bunk B, Johns MA, Edirisinghe JN, Kutumbaka KK, Koenig SS, Creasy HH, Rosovitz MJ, Riley DR, Daugherty S, Martin M, Elbourne LD, Paulsen I, Biedendieck R, Braun C, Grayburn S, Dhingra S, Lukyanchuk V, Ball B, Ul-Qamar R, Seibel J, Bremer E, Jahn D, Ravel J, Vary PS.

J Bacteriol. 2011 Aug;193(16):4199-213. doi: 10.1128/JB.00449-11. Epub 2011 Jun 24.


A short story about a big magic bug.

Bunk B, Schulz A, Stammen S, Münch R, Warren MJ, Rohde M, Jahn D, Biedendieck R.

Bioeng Bugs. 2010 Mar-Apr;1(2):85-91. doi: 10.4161/bbug.1.2.11101. Epub 2010 Jan 4.


Metabolic engineering of cobalamin (vitamin B12) production in Bacillus megaterium.

Biedendieck R, Malten M, Barg H, Bunk B, Martens JH, Deery E, Leech H, Warren MJ, Jahn D.

Microb Biotechnol. 2010 Jan;3(1):24-37. doi: 10.1111/j.1751-7915.2009.00125.x. Epub 2009 Jun 10.


Application of Escherichia coli phage K1E DNA-dependent RNA polymerase for in vitro RNA synthesis and in vivo protein production in Bacillus megaterium.

Stammen S, Schuller F, Dietrich S, Gamer M, Biedendieck R, Jahn D.

Appl Microbiol Biotechnol. 2010 Sep;88(2):529-39. doi: 10.1007/s00253-010-2732-y. Epub 2010 Jul 2.


Heme biosynthesis is coupled to electron transport chains for energy generation.

Möbius K, Arias-Cartin R, Breckau D, Hännig AL, Riedmann K, Biedendieck R, Schröder S, Becher D, Magalon A, Moser J, Jahn M, Jahn D.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10436-41. doi: 10.1073/pnas.1000956107. Epub 2010 May 19.


High-yield intra- and extracellular protein production using Bacillus megaterium.

Stammen S, Müller BK, Korneli C, Biedendieck R, Gamer M, Franco-Lara E, Jahn D.

Appl Environ Microbiol. 2010 Jun;76(12):4037-46. doi: 10.1128/AEM.00431-10. Epub 2010 Apr 30.


Systems biology of recombinant protein production in Bacillus megaterium.

Biedendieck R, Bunk B, Fürch T, Franco-Lara E, Jahn M, Jahn D.

Adv Biochem Eng Biotechnol. 2010;120:133-61. doi: 10.1007/10_2009_62.


A T7 RNA polymerase-dependent gene expression system for Bacillus megaterium.

Gamer M, Fröde D, Biedendieck R, Stammen S, Jahn D.

Appl Microbiol Biotechnol. 2009 Apr;82(6):1195-203. doi: 10.1007/s00253-009-1952-5. Epub 2009 Mar 24.


Demonstration that CobG, the monooxygenase associated with the ring contraction process of the aerobic cobalamin (vitamin B12) biosynthetic pathway, contains an Fe-S center and a mononuclear non-heme iron center.

Schroeder S, Lawrence AD, Biedendieck R, Rose RS, Deery E, Graham RM, McLean KJ, Munro AW, Rigby SE, Warren MJ.

J Biol Chem. 2009 Feb 20;284(8):4796-805. doi: 10.1074/jbc.M807184200. Epub 2008 Dec 8.


A sucrose-inducible promoter system for the intra- and extracellular protein production in Bacillus megaterium.

Biedendieck R, Gamer M, Jaensch L, Meyer S, Rohde M, Deckwer WD, Jahn D.

J Biotechnol. 2007 Dec 1;132(4):426-30. Epub 2007 Jul 10.


Bacillus megaterium--from simple soil bacterium to industrial protein production host.

Vary PS, Biedendieck R, Fuerch T, Meinhardt F, Rohde M, Deckwer WD, Jahn D.

Appl Microbiol Biotechnol. 2007 Oct;76(5):957-67. Epub 2007 Jul 26. Review.


D-mannitol production by resting state whole cell biotrans-formation of D-fructose by heterologous mannitol and formate dehydrogenase gene expression in Bacillus megaterium.

Bäumchen C, Roth AH, Biedendieck R, Malten M, Follmann M, Sahm H, Bringer-Meyer S, Jahn D.

Biotechnol J. 2007 Nov;2(11):1408-16.


Export, purification, and activities of affinity tagged Lactobacillus reuteri levansucrase produced by Bacillus megaterium.

Biedendieck R, Beine R, Gamer M, Jordan E, Buchholz K, Seibel J, Dijkhuizen L, Malten M, Jahn D.

Appl Microbiol Biotechnol. 2007 Apr;74(5):1062-73. Epub 2007 Jan 24.


Production of recombinant antibody fragments in Bacillus megaterium.

Jordan E, Hust M, Roth A, Biedendieck R, Schirrmann T, Jahn D, Dübel S.

Microb Cell Fact. 2007 Jan 15;6:2.


High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium.

Yang Y, Biedendieck R, Wang W, Gamer M, Malten M, Jahn D, Deckwer WD.

Microb Cell Fact. 2006 Nov 28;5:36.


Plasmid system for the intracellular production and purification of affinity-tagged proteins in Bacillus megaterium.

Biedendieck R, Yang Y, Deckwer WD, Malten M, Jahn D.

Biotechnol Bioeng. 2007 Feb 15;96(3):525-37.


A Bacillus megaterium plasmid system for the production, export, and one-step purification of affinity-tagged heterologous levansucrase from growth medium.

Malten M, Biedendieck R, Gamer M, Drews AC, Stammen S, Buchholz K, Dijkhuizen L, Jahn D.

Appl Environ Microbiol. 2006 Feb;72(2):1677-9.

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