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Items: 20

1.

Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling.

Chien AJ, Haydu LE, Biechele TL, Kulikauskas RM, Rizos H, Kefford RF, Scolyer RA, Moon RT, Long GV.

PLoS One. 2014 Apr 14;9(4):e94748. doi: 10.1371/journal.pone.0094748. eCollection 2014.

2.

Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling.

Robin NC, Agoston Z, Biechele TL, James RG, Berndt JD, Moon RT.

Stem Cell Reports. 2013 Dec 26;2(1):9-17. doi: 10.1016/j.stemcr.2013.11.002. eCollection 2014 Jan 14.

3.

Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.

James RG, Bosch KA, Kulikauskas RM, Yang PT, Robin NC, Toroni RA, Biechele TL, Berndt JD, von Haller PD, Eng JK, Wolf-Yadlin A, Chien AJ, Moon RT.

J Biol Chem. 2013 Nov 29;288(48):34658-70. doi: 10.1074/jbc.M113.500314. Epub 2013 Oct 10.

4.

WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling.

James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT.

PLoS One. 2012;7(12):e50457. doi: 10.1371/journal.pone.0050457. Epub 2012 Dec 5.

5.

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ.

Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16.

6.

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4.

Davidson KC, Adams AM, Goodson JM, McDonald CE, Potter JC, Berndt JD, Biechele TL, Taylor RJ, Moon RT.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4485-90. doi: 10.1073/pnas.1118777109. Epub 2012 Mar 5.

7.

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ.

Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274.

8.

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT.

Oncogene. 2012 Aug 9;31(32):3696-708. doi: 10.1038/onc.2011.528. Epub 2011 Dec 19.

9.

Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3.

Oikonomopoulos A, Sereti KI, Conyers F, Bauer M, Liao A, Guan J, Crapps D, Han JK, Dong H, Bayomy AF, Fine GC, Westerman K, Biechele TL, Moon RT, Force T, Liao R.

Circ Res. 2011 Dec 9;109(12):1363-74. doi: 10.1161/CIRCRESAHA.111.250282. Epub 2011 Oct 27.

10.

AKT kinase activity is required for lithium to modulate mood-related behaviors in mice.

Pan JQ, Lewis MC, Ketterman JK, Clore EL, Riley M, Richards KR, Berry-Scott E, Liu X, Wagner FF, Holson EB, Neve RL, Biechele TL, Moon RT, Scolnick EM, Petryshen TL, Haggarty SJ.

Neuropsychopharmacology. 2011 Jun;36(7):1397-411. doi: 10.1038/npp.2011.24. Epub 2011 Mar 9.

11.

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.

Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT.

Chem Biol. 2010 Nov 24;17(11):1177-82. doi: 10.1016/j.chembiol.2010.08.012.

12.

Re: Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.

Biechele TL, Chien AJ.

Carcinogenesis. 2011 Jan;32(1):120; author reply 121. doi: 10.1093/carcin/bgq217. Epub 2010 Oct 27. No abstract available.

PMID:
20980347
13.

Transcription-based reporters of Wnt/beta-catenin signaling.

Biechele TL, Adams AM, Moon RT.

Cold Spring Harb Protoc. 2009 Jun;2009(6):pdb.prot5223. doi: 10.1101/pdb.prot5223. No abstract available.

PMID:
20147181
14.

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.

James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT.

Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230.

15.

Integrative analysis of genome-wide RNA interference screens.

Berndt JD, Biechele TL, Moon RT, Major MB.

Sci Signal. 2009 May 12;2(70):pt4. doi: 10.1126/scisignal.270pt4.

PMID:
19436058
16.

Assaying beta-catenin/TCF transcription with beta-catenin/TCF transcription-based reporter constructs.

Biechele TL, Moon RT.

Methods Mol Biol. 2008;468:99-110. doi: 10.1007/978-1-59745-249-6_8.

PMID:
19099249
17.

Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells.

Woll PS, Morris JK, Painschab MS, Marcus RK, Kohn AD, Biechele TL, Moon RT, Kaufman DS.

Blood. 2008 Jan 1;111(1):122-31. Epub 2007 Sep 17.

18.

Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma.

Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA.

J Immunol. 2007 Jun 15;178(12):7879-89.

19.

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.

Science. 2007 May 18;316(5827):1043-6.

20.

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT.

Nat Cell Biol. 2006 Apr;8(4):348-57. Epub 2006 Mar 19.

PMID:
16547521

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