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Items: 25

1.

CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease.

Döring Y, van der Vorst EPC, Duchene J, Jansen Y, Gencer S, Bidzhekov K, Atzler D, Santovito D, Rader DJ, Saleheen D, Weber C.

Circulation. 2019 Mar 5;139(10):1338-1340. doi: 10.1161/CIRCULATIONAHA.118.037953. No abstract available.

PMID:
30865486
2.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29.

PMID:
30709741
3.

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.

Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.

Circulation. 2017 Jul 25;136(4):388-403. doi: 10.1161/CIRCULATIONAHA.117.027646. Epub 2017 Apr 27.

4.

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.

PMID:
28381538
5.

The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.

Schloss MJ, Horckmans M, Nitz K, Duchene J, Drechsler M, Bidzhekov K, Scheiermann C, Weber C, Soehnlein O, Steffens S.

EMBO Mol Med. 2016 Aug 1;8(8):937-48. doi: 10.15252/emmm.201506083. Print 2016 Aug.

6.

Recurrent spontaneous coronary dissections in a patient with a de novo fibrillin-1 mutation without Marfan syndrome.

von Hundelshausen P, Oexle K, Bidzhekov K, Schmitt MM, Hristov M, Blanchet X, Kaemmerer H, Matyas G, Meitinger T, Weber C.

Thromb Haemost. 2015 Mar;113(3):668-70. doi: 10.1160/TH14-11-0913. Epub 2014 Dec 18. No abstract available.

PMID:
25519456
7.

Hyperreactivity of junctional adhesion molecule A-deficient platelets accelerates atherosclerosis in hyperlipidemic mice.

Karshovska E, Zhao Z, Blanchet X, Schmitt MM, Bidzhekov K, Soehnlein O, von Hundelshausen P, Mattheij NJ, Cosemans JM, Megens RT, Koeppel TA, Schober A, Hackeng TM, Weber C, Koenen RR.

Circ Res. 2015 Feb 13;116(4):587-99. doi: 10.1161/CIRCRESAHA.116.304035. Epub 2014 Dec 3.

PMID:
25472975
8.

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1.

Schober A, Nazari-Jahantigh M, Wei Y, Bidzhekov K, Gremse F, Grommes J, Megens RT, Heyll K, Noels H, Hristov M, Wang S, Kiessling F, Olson EN, Weber C.

Nat Med. 2014 Apr;20(4):368-76. doi: 10.1038/nm.3487. Epub 2014 Mar 2.

9.

Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis.

Schmitt MM, Megens RT, Zernecke A, Bidzhekov K, van den Akker NM, Rademakers T, van Zandvoort MA, Hackeng TM, Koenen RR, Weber C.

Circulation. 2014 Jan 7;129(1):66-76. doi: 10.1161/CIRCULATIONAHA.113.004149. Epub 2013 Sep 24.

PMID:
24065611
10.

microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans.

Bidzhekov K, Gan L, Denecke B, Rostalsky A, Hristov M, Koeppel TA, Zernecke A, Weber C.

Thromb Haemost. 2012 Apr;107(4):619-25. doi: 10.1160/TH11-09-0607. Epub 2012 Feb 28.

PMID:
22370758
11.

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.

Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A.

J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925.

12.

C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice.

Shagdarsuren E, Bidzhekov K, Mause SF, Simsekyilmaz S, Polakowski T, Hawlisch H, Gessner JE, Zernecke A, Weber C.

Circulation. 2010 Sep 7;122(10):1026-36. doi: 10.1161/CIRCULATIONAHA.110.954370. Epub 2010 Aug 23.

PMID:
20733098
13.

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.

Massberg S, Grahl L, von Bruehl ML, Manukyan D, Pfeiler S, Goosmann C, Brinkmann V, Lorenz M, Bidzhekov K, Khandagale AB, Konrad I, Kennerknecht E, Reges K, Holdenrieder S, Braun S, Reinhardt C, Spannagl M, Preissner KT, Engelmann B.

Nat Med. 2010 Aug;16(8):887-96. doi: 10.1038/nm.2184. Epub 2010 Aug 1.

PMID:
20676107
14.

Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury.

Mause SF, Ritzel E, Liehn EA, Hristov M, Bidzhekov K, Müller-Newen G, Soehnlein O, Weber C.

Circulation. 2010 Aug 3;122(5):495-506. doi: 10.1161/CIRCULATIONAHA.109.909473. Epub 2010 Jul 19.

PMID:
20644015
15.

Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection.

Zernecke A, Bidzhekov K, Noels H, Shagdarsuren E, Gan L, Denecke B, Hristov M, Köppel T, Jahantigh MN, Lutgens E, Wang S, Olson EN, Schober A, Weber C.

Sci Signal. 2009 Dec 8;2(100):ra81. doi: 10.1126/scisignal.2000610.

PMID:
19996457
16.

Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report.

Shagdarsuren E, Djalali-Talab Y, Aurrand-Lions M, Bidzhekov K, Liehn EA, Imhof BA, Weber C, Zernecke A.

Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1161-3. doi: 10.1161/ATVBAHA.109.187898. Epub 2009 Jun 11.

PMID:
19520977
17.

Neutrophil secretion products pave the way for inflammatory monocytes.

Soehnlein O, Zernecke A, Eriksson EE, Rothfuchs AG, Pham CT, Herwald H, Bidzhekov K, Rottenberg ME, Weber C, Lindbom L.

Blood. 2008 Aug 15;112(4):1461-71. doi: 10.1182/blood-2008-02-139634. Epub 2008 May 19.

18.

Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.

Bidzhekov K, Hautmann M, Semisch M, Weber C, Engelmann B, Hatzopoulos AK.

J Cell Mol Med. 2007 Nov-Dec;11(6):1395-407. doi: 10.1111/j.1582-4934.2007.00123.x.

19.

C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice.

Shagdarsuren E, Bidzhekov K, Djalali-Talab Y, Liehn EA, Hristov M, Matthijsen RA, Buurman WA, Zernecke A, Weber C.

Circulation. 2008 Jan 1;117(1):70-8. Epub 2007 Dec 10. Erratum in: Circulation. 2008 Jan 29;117(4):e147.

PMID:
18071075
20.

Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis.

Zernecke A, Bot I, Djalali-Talab Y, Shagdarsuren E, Bidzhekov K, Meiler S, Krohn R, Schober A, Sperandio M, Soehnlein O, Bornemann J, Tacke F, Biessen EA, Weber C.

Circ Res. 2008 Feb 1;102(2):209-17. Epub 2007 Nov 8.

PMID:
17991882
21.

Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury.

Hristov M, Zernecke A, Bidzhekov K, Liehn EA, Shagdarsuren E, Ludwig A, Weber C.

Circ Res. 2007 Mar 2;100(4):590-7. Epub 2007 Feb 1.

PMID:
17272812
22.

Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.

Braunersreuther V, Zernecke A, Arnaud C, Liehn EA, Steffens S, Shagdarsuren E, Bidzhekov K, Burger F, Pelli G, Luckow B, Mach F, Weber C.

Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):373-9. Epub 2006 Nov 30.

PMID:
17138939
23.

Eosinophils are a major intravascular location for tissue factor storage and exposure.

Moosbauer C, Morgenstern E, Cuvelier SL, Manukyan D, Bidzhekov K, Albrecht S, Lohse P, Patel KD, Engelmann B.

Blood. 2007 Feb 1;109(3):995-1002. Epub 2006 Sep 26.

24.

MCP-1 induces a novel transcription factor with proapoptotic activity.

Bidzhekov K, Zernecke A, Weber C.

Circ Res. 2006 May 12;98(9):1107-9. Review. No abstract available.

PMID:
16690887
25.

CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation.

Zernecke A, Bidzhekov K, Ozüyaman B, Fraemohs L, Liehn EA, Lüscher-Firzlaff JM, Lüscher B, Schrader J, Weber C.

Circulation. 2006 May 2;113(17):2120-7. Epub 2006 Apr 24.

PMID:
16636171

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