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Items: 1 to 50 of 66

1.

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Mouradov D, Sloggett C, Jorissen RN, Love CG, Li S, Burgess AW, Arango D, Strausberg RL, Buchanan D, Wormald S, O'Connor L, Wilding JL, Bicknell D, Tomlinson IP, Bodmer WF, Mariadason JM, Sieber OM.

Cancer Res. 2014 Jun 15;74(12):3238-47. doi: 10.1158/0008-5472.CAN-14-0013. Epub 2014 Apr 22.

2.

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.

Chan CW, Wong NA, Liu Y, Bicknell D, Turley H, Hollins L, Miller CJ, Wilding JL, Bodmer WF.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41. doi: 10.1073/pnas.0812904106. Epub 2009 Feb 2.

3.

Use of an optimized 1,2-indanedione process for the development of latent prints*.

Bicknell DE, Ramotowski RS.

J Forensic Sci. 2008 Sep;53(5):1108-16. doi: 10.1111/j.1556-4029.2008.00826.x. Epub 2008 Jul 15.

PMID:
18637975
4.

Mutations in the AXIN1 gene in advanced prostate cancer.

Yardy GW, Bicknell DC, Wilding JL, Bartlett S, Liu Y, Winney B, Turner GD, Brewster SF, Bodmer WF.

Eur Urol. 2009 Sep;56(3):486-94. doi: 10.1016/j.eururo.2008.05.029. Epub 2008 May 23.

PMID:
18514389
5.

Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen.

Conaghan P, Ashraf S, Tytherleigh M, Wilding J, Tchilian E, Bicknell D, Mortensen NJ, Bodmer W.

Br J Cancer. 2008 Apr 8;98(7):1217-25. doi: 10.1038/sj.bjc.6604289. Epub 2008 Mar 18.

6.

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.

Emaduddin M, Bicknell DC, Bodmer WF, Feller SM.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2358-62. doi: 10.1073/pnas.0712176105. Epub 2008 Feb 7.

7.

Multigene amplification and massively parallel sequencing for cancer mutation discovery.

Dahl F, Stenberg J, Fredriksson S, Welch K, Zhang M, Nilsson M, Bicknell D, Bodmer WF, Davis RW, Ji H.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9387-92. Epub 2007 May 17.

8.

Observed smoking in cars: a method and differences by socioeconomic area.

Martin J, George R, Andrews K, Barr P, Bicknell D, Insull E, Knox C, Liu J, Naqshband M, Romeril K, Wong D, Thomson G, Wilson N.

Tob Control. 2006 Oct;15(5):409-11.

9.

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers.

Gaasenbeek M, Howarth K, Rowan AJ, Gorman PA, Jones A, Chaplin T, Liu Y, Bicknell D, Davison EJ, Fiegler H, Carter NP, Roylance RR, Tomlinson IP.

Cancer Res. 2006 Apr 1;66(7):3471-9.

10.

A mutated HLA-A*0101 allele in the colorectal cell line HCA-7.

Bicknell DC, Bodmer WF.

Tissue Antigens. 2005 Sep;66(3):231-7.

PMID:
16101834
11.

Preclinical application of radioimmunoguided surgery using anti-carcinoembryonic antigen biparatopic antibody in the colon cancer.

Kim JC, Roh SA, Koo KH, Cho YK, Kim HC, Yu CS, Oh SJ, Ryu JS, Bicknell DC, Bodmer WF.

Eur Surg Res. 2005 Jan-Feb;37(1):36-44.

PMID:
15818040
12.

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC, Tomlinson IP, Mortensen NJ, Bodmer WF.

Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15992-7. Epub 2004 Nov 1.

13.

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas.

Douglas EJ, Fiegler H, Rowan A, Halford S, Bicknell DC, Bodmer W, Tomlinson IP, Carter NP.

Cancer Res. 2004 Jul 15;64(14):4817-25.

14.

Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines.

Wong NA, Britton MP, Choi GS, Stanton TK, Bicknell DC, Wilding JL, Bodmer WF.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):574-9. Epub 2004 Jan 2.

15.

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags.

Brentani H, Caballero OL, Camargo AA, da Silva AM, da Silva WA Jr, Dias Neto E, Grivet M, Gruber A, Guimaraes PE, Hide W, Iseli C, Jongeneel CV, Kelso J, Nagai MA, Ojopi EP, Osorio EC, Reis EM, Riggins GJ, Simpson AJ, de Souza S, Stevenson BJ, Strausberg RL, Tajara EH, Verjovski-Almeida S, Acencio ML, Bengtson MH, Bettoni F, Bodmer WF, Briones MR, Camargo LP, Cavenee W, Cerutti JM, Coelho Andrade LE, Costa dos Santos PC, Ramos Costa MC, da Silva IT, Estécio MR, Sa Ferreira K, Furnari FB, Faria M Jr, Galante PA, Guimaraes GS, Holanda AJ, Kimura ET, Leerkes MR, Lu X, Maciel RM, Martins EA, Massirer KB, Melo AS, Mestriner CA, Miracca EC, Miranda LL, Nobrega FG, Oliveira PS, Paquola AC, Pandolfi JR, Campos Pardini MI, Passetti F, Quackenbush J, Schnabel B, Sogayar MC, Souza JE, Valentini SR, Zaiats AC, Amaral EJ, Arnaldi LA, de Araújo AG, de Bessa SA, Bicknell DC, Ribeiro de Camaro ME, Carraro DM, Carrer H, Carvalho AF, Colin C, Costa F, Curcio C, Guerreiro da Silva ID, Pereira da Silva N, Dellamano M, El-Dorry H, Espreafico EM, Scattone Ferreira AJ, Ayres Ferreira C, Fortes MA, Gama AH, Giannella-Neto D, Giannella ML, Giorgi RR, Goldman GH, Goldman MH, Hackel C, Ho PL, Kimura EM, Kowalski LP, Krieger JE, Leite LC, Lopes A, Luna AM, Mackay A, Mari SK, Marques AA, Martins WK, Montagnini A, Mourão Neto M, Nascimento AL, Neville AM, Nobrega MP, O'Hare MJ, Otsuka AY, Ruas de Melo AI, Paco-Larson ML, Guimarães Pereira G, Pereira da Silva N, Pesquero JB, Pessoa JG, Rahal P, Rainho CA, Rodrigues V, Rogatto SR, Romano CM, Romeiro JG, Rossi BM, Rusticci M, Guerra de Sá R, Sant' Anna SC, Sarmazo ML, Silva TC, Soares FA, Sonati Mde F, de Freitas Sousa J, Queiroz D, Valente V, Vettore AL, Villanova FE, Zago MA, Zalcberg H; Human Cancer Genome Project/Cancer Genome Anatomy Project Annotation Consortium; Human Cancer Genome Project Sequencing Consortium.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13418-23. Epub 2003 Oct 30.

16.

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. Epub 2001 Jul 31.

17.

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.

Woodford-Richens KL, Halford S, Rowan A, Bevan S, Aaltonen LA, Wasan H, Bicknell D, Bodmer WF, Houlston RS, Tomlinson IP.

Br J Cancer. 2001 May 18;84(10):1314-6.

18.

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

Abdel-Rahman WM, Katsura K, Rens W, Gorman PA, Sheer D, Bicknell D, Bodmer WF, Arends MJ, Wyllie AH, Edwards PA.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2538-43. Epub 2001 Feb 20.

19.

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.

Playford MP, Bicknell D, Bodmer WF, Macaulay VM.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12103-8.

20.

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".

Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3352-7.

21.

Carcino-embryonic antigen may function as a chemo-attractant in colorectal-carcinoma cell lines.

Kim JC, Koo KH, Kim BS, Park KC, Bicknell DC, Bodmer WF.

Int J Cancer. 1999 Sep 9;82(6):880-5.

22.

Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.

Rowan A, Bataille V, MacKie R, Healy E, Bicknell D, Bodmer W, Tomlinson I.

J Invest Dermatol. 1999 Apr;112(4):509-11.

23.

Selection for beta 2-microglobulin mutation in mismatch repair-defective colorectal carcinomas.

Bicknell DC, Kaklamanis L, Hampson R, Bodmer WF, Karran P.

Curr Biol. 1996 Dec 1;6(12):1695-7.

24.

Mechanisms of loss of HLA class I expression on colorectal tumor cells.

Browning M, Petronzelli F, Bicknell D, Krausa P, Rowan A, Tonks S, Murray N, Bodmer J, Bodmer W.

Tissue Antigens. 1996 May;47(5):364-71.

PMID:
8795136
25.

Immune surveillance in colorectal carcinoma.

Branch P, Bicknell DC, Rowan A, Bodmer WF, Karran P.

Nat Genet. 1995 Mar;9(3):231-2. No abstract available.

PMID:
7773283
26.

Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors.

Bicknell DC, Rowan A, Bodmer WF.

Proc Natl Acad Sci U S A. 1994 May 24;91(11):4751-5.

27.

Loss of human leukocyte antigen expression on colorectal tumor cell lines: implications for anti-tumor immunity and immunotherapy.

Browning MJ, Krausa P, Rowan A, Hill AB, Bicknell DC, Bodmer JG, Bodmer WF.

J Immunother Emphasis Tumor Immunol. 1993 Oct;14(3):163-8.

PMID:
8297898
28.

Tumor escape from immune response by variation in HLA expression and other mechanisms.

Bodmer WF, Browning MJ, Krausa P, Rowan A, Bicknell DC, Bodmer JG.

Ann N Y Acad Sci. 1993 Aug 12;690:42-9. Review. No abstract available.

PMID:
8368769
29.

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

Browning MJ, Krausa P, Rowan A, Bicknell DC, Bodmer JG, Bodmer WF.

Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2842-5.

30.

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.

Cottrell S, Bicknell D, Kaklamanis L, Bodmer WF.

Lancet. 1992 Sep 12;340(8820):626-30.

PMID:
1355210
31.

The human chromosome content in human x rodent somatic cell hybrids analyzed by a screening technique using Alu PCR.

Bicknell DC, Markie D, Spurr NK, Bodmer WF.

Genomics. 1991 May;10(1):186-92.

PMID:
2045101
33.

Alkaline phosphatases.

Trowsdale J, Martin D, Bicknell D, Campbell I.

Biochem Soc Trans. 1990 Apr;18(2):178-80. No abstract available.

PMID:
2379681
34.

Consent for children and adolescents who have an intellectual handicap.

Bicknell DJ.

Arch Dis Child. 1989 Nov;64(11):1529-32. Review. No abstract available.

35.

Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis.

Broxmeyer HE, Williams DE, Geissler K, Hangoc G, Cooper S, Bicknell DC, Levi S, Arosio P.

Blood. 1989 Jan;73(1):74-9.

36.

Synergistic interaction of hematopoietic colony stimulating and growth factors in the regulation of myelopoiesis.

Broxmeyer HE, Williams DE, Cooper S, Ralph P, Gillis S, Bicknell DC, Hangoc G, Drummond R, Lu L.

Behring Inst Mitt. 1988 Aug;(83):80-4.

PMID:
3266466
38.

Purified murine granulocyte/macrophage progenitor cells express a high-affinity receptor for recombinant murine granulocyte/macrophage colony-stimulating factor.

Williams DE, Bicknell DC, Park LS, Straneva JE, Cooper S, Broxmeyer HE.

Proc Natl Acad Sci U S A. 1988 Jan;85(2):487-91.

40.

Modulation of Friend virus infectivity in vivo by administration of purified preparations of human lactoferrin and recombinant murine interleukin-3 to mice.

Hangoc G, Lu L, Oliff A, Gillis S, Hu W, Bicknell DC, Williams D, Broxmeyer HE.

Leukemia. 1987 Nov;1(11):762-4.

PMID:
3500373
42.
43.

The opposing actions in vivo on murine myelopoiesis of purified preparations of lactoferrin and the colony stimulating factors.

Broxmeyer HE, Williams DE, Hangoc G, Cooper S, Gentile P, Shen RN, Ralph P, Gillis S, Bicknell DC.

Blood Cells. 1987;13(1-2):31-48.

PMID:
3499193
44.
46.

Monoclonal antibody (II2C) to human lactoferrin inactivates the myelopoietic suppressive effect of human lactoferrin in vitro.

Sledge GW Jr, Bicknell DC, Harris EL, Zegarra G, Broxmeyer HE.

Exp Hematol. 1986 Jun;14(5):333-7.

PMID:
3709705
47.

Structural and functional features of a cell surface phosphoglycoprotein associated with tumorigenic phenotype in human fibroblast x HeLa cell hybrids.

Sutherland DR, Bicknell DC, Downward J, Parker P, Waterfield MD, Baker MA, Greaves MF, Stanbridge EJ.

J Biol Chem. 1986 Feb 15;261(5):2418-24.

49.
50.

Monoclonal antibodies specific for a tumor-associated membrane phosphoprotein in human cell hybrids.

Bicknell DC, Sutherland DR, Stanbridge EJ, Greaves MF.

Hybridoma. 1985 Summer;4(2):143-52.

PMID:
2408990

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