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Items: 1 to 50 of 230

1.

SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas.

Kim AL, Back JH, Chaudhary SC, Zhu Y, Athar M, Bickers DR.

J Invest Dermatol. 2018 Mar 14. pii: S0022-202X(18)30229-X. doi: 10.1016/j.jid.2018.01.040. [Epub ahead of print]

PMID:
29550418
2.

Correction: Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation.

Liu L, Rezvani HR, Back JH, Hosseini M, Tang X, Zhu Y, Mahfouf W, Raad H, Ragi G, Athar M, Kim AL, Bickers DR.

PLoS One. 2017 Feb 14;12(2):e0172451. doi: 10.1371/journal.pone.0172451. eCollection 2017.

3.

Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.

Tang JY, Ally MS, Chanana AM, Mackay-Wiggan JM, Aszterbaum M, Lindgren JA, Ulerio G, Rezaee MR, Gildengorin G, Marji J, Clark C, Bickers DR, Epstein EH Jr.

Lancet Oncol. 2016 Dec;17(12):1720-1731. doi: 10.1016/S1470-2045(16)30566-6. Epub 2016 Nov 10.

PMID:
27838224
4.

AKT1 Activation is Obligatory for Spontaneous BCC Tumor Growth in a Murine Model that Mimics Some Features of Basal Cell Nevus Syndrome.

Kim AL, Back JH, Zhu Y, Tang X, Yardley NP, Kim KJ, Athar M, Bickers DR.

Cancer Prev Res (Phila). 2016 Oct;9(10):794-802. Epub 2016 Jul 7.

5.

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.

Chaudhary SC, Tang X, Arumugam A, Li C, Srivastava RK, Weng Z, Xu J, Zhang X, Kim AL, McKay K, Elmets CA, Kopelovich L, Bickers DR, Athar M.

Oncotarget. 2015 Nov 3;6(34):36789-814. doi: 10.18632/oncotarget.5103.

6.

Leonard C. Harber (1927-2014).

Bickers DR.

J Invest Dermatol. 2015 Apr;135(4):935-6. doi: 10.1038/jid.2014.550. No abstract available.

7.

The scientific legacy of Stephen Rothman.

Burgdorf WHC, Bickers DR.

J Invest Dermatol. 2015 Apr;135(4):954-959. doi: 10.1038/jid.2014.447. Epub 2014 Nov 6. Review.

8.

Sonic hedgehog signaling in Basal cell nevus syndrome.

Athar M, Li C, Kim AL, Spiegelman VS, Bickers DR.

Cancer Res. 2014 Sep 15;74(18):4967-75. doi: 10.1158/0008-5472.CAN-14-1666. Epub 2014 Aug 29. Review.

9.

Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation.

Liu L, Rezvani HR, Back JH, Hosseini M, Tang X, Zhu Y, Mahfouf W, Raad H, Ragi G, Athar M, Kim AL, Bickers DR.

PLoS One. 2014 May 13;9(5):e97245. doi: 10.1371/journal.pone.0097245. eCollection 2014. Erratum in: PLoS One. 2017 Feb 14;12 (2):e0172451.

10.

Strange bedfellows.

Burgdorf WH, Bickers DR, Hoenig LJ.

JAMA Dermatol. 2014 Apr;150(4):365. doi: 10.1001/jamadermatol.2013.9136. No abstract available.

PMID:
24718427
11.

Hair follicle disruption facilitates pathogenesis to UVB-induced cutaneous inflammation and basal cell carcinoma development in Ptch(+/-) mice.

Xu J, Weng Z, Arumugam A, Tang X, Chaudhary SC, Li C, Christiano AM, Elmets CA, Bickers DR, Athar M.

Am J Pathol. 2014 May;184(5):1529-40. doi: 10.1016/j.ajpath.2014.01.013. Epub 2014 Mar 12.

12.

The use of vismodegib to shrink keratocystic odontogenic tumors in patients with basal cell nevus syndrome.

Ally MS, Tang JY, Joseph T, Thompson B, Lindgren J, Raphael MA, Ulerio G, Chanana AM, Mackay-Wiggan JM, Bickers DR, Epstein EH Jr.

JAMA Dermatol. 2014 May;150(5):542-5. doi: 10.1001/jamadermatol.2013.7444.

13.

Tazarotene: randomized, double-blind, vehicle-controlled, and open-label concurrent trials for basal cell carcinoma prevention and therapy in patients with basal cell nevus syndrome.

Tang JY, Chiou AS, Mackay-Wiggan JM, Aszterbaum M, Chanana AM, Lee W, Lindgren JA, Raphael MA, Thompson BJ, Bickers DR, Epstein EH Jr.

Cancer Prev Res (Phila). 2014 Mar;7(3):292-9. doi: 10.1158/1940-6207.CAPR-13-0305. Epub 2014 Jan 17.

14.

Downregulation of STRA6 expression in epidermal keratinocytes leads to hyperproliferation-associated differentiation in both in vitro and in vivo skin models.

Skazik C, Amann PM, Heise R, Marquardt Y, Czaja K, Kim A, Rühl R, Kurschat P, Merk HF, Bickers DR, Baron JM.

J Invest Dermatol. 2014 Jun;134(6):1579-1588. doi: 10.1038/jid.2013.507. Epub 2013 Nov 27.

15.

Bechet vs Behçet: the name is not the same.

Burgdorf WH, Bickers DR, Hoenig LJ.

JAMA Dermatol. 2013 Oct;149(10):1223. doi: 10.1001/jamadermatol.2013.7559. No abstract available.

PMID:
24132319
16.

Dermatologic relationships between the United States and German-speaking countries: part 3--the Europeans come to the United States.

Burgdorf WH, Bickers DR.

JAMA Dermatol. 2013 Oct;149(10):1217-20. doi: 10.1001/jamadermatol.2013.5783.

PMID:
24026481
17.

Dermatologic relationships between the United States and German-speaking countries: part 2--the exodus of Jewish dermatologists.

Burgdorf WH, Bickers DR.

JAMA Dermatol. 2013 Sep;149(9):1090-4. doi: 10.1001/jamadermatol.2013.5023.

PMID:
23986294
18.

Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption.

Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):879-87. doi: 10.1016/j.taap.2013.08.004. Epub 2013 Aug 14.

19.
20.

Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling.

Kim H, Casta A, Tang X, Luke CT, Kim AL, Bickers DR, Athar M, Christiano AM.

PLoS One. 2012;7(6):e39691. doi: 10.1371/journal.pone.0039691. Epub 2012 Jun 25.

21.

Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome.

Tang JY, Mackay-Wiggan JM, Aszterbaum M, Yauch RL, Lindgren J, Chang K, Coppola C, Chanana AM, Marji J, Bickers DR, Epstein EH Jr.

N Engl J Med. 2012 Jun 7;366(23):2180-8. doi: 10.1056/NEJMoa1113538.

22.
23.

Ultraviolet B radiation and reactive oxygen species modulate interleukin-31 expression in T lymphocytes, monocytes and dendritic cells.

Cornelissen C, Brans R, Czaja K, Skazik C, Marquardt Y, Zwadlo-Klarwasser G, Kim A, Bickers DR, Lüscher-Firzlaff J, Lüscher B, Baron JM.

Br J Dermatol. 2011 Nov;165(5):966-75. doi: 10.1111/j.1365-2133.2011.10487.x. Epub 2011 Oct 17.

PMID:
21711332
24.

P-glycoprotein (ABCB1) expression in human skin is mainly restricted to dermal components.

Skazik C, Wenzel J, Marquardt Y, Kim A, Merk HF, Bickers DR, Baron JM.

Exp Dermatol. 2011 May;20(5):450-2. doi: 10.1111/j.1600-0625.2010.01237.x. Epub 2011 Mar 1.

PMID:
21366702
25.

XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas.

Rezvani HR, Kim AL, Rossignol R, Ali N, Daly M, Mahfouf W, Bellance N, Taïeb A, de Verneuil H, Mazurier F, Bickers DR.

J Clin Invest. 2011 Jan;121(1):195-211. doi: 10.1172/JCI40087. Epub 2010 Dec 1.

26.

High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome.

Tang JY, Wu A, Linos E, Parimi N, Lee W, Aszterbaum M, Asgari MM, Bickers DR, Epstein EH Jr.

Arch Dermatol. 2010 Oct;146(10):1105-10. doi: 10.1001/archdermatol.2010.247.

27.

Resveratrol targets transforming growth factor-β2 signaling to block UV-induced tumor progression.

Kim KH, Back JH, Zhu Y, Arbesman J, Athar M, Kopelovich L, Kim AL, Bickers DR.

J Invest Dermatol. 2011 Jan;131(1):195-202. doi: 10.1038/jid.2010.250. Epub 2010 Aug 19.

28.

Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice.

Tang JY, Aszterbaum M, Athar M, Barsanti F, Cappola C, Estevez N, Hebert J, Hwang J, Khaimskiy Y, Kim A, Lu Y, So PL, Tang X, Kohn MA, McCulloch CE, Kopelovich L, Bickers DR, Epstein EH Jr.

Cancer Prev Res (Phila). 2010 Jan;3(1):25-34. doi: 10.1158/1940-6207.CAPR-09-0200.

29.

Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes.

Rezvani HR, Mahfouf W, Ali N, Chemin C, Ged C, Kim AL, de Verneuil H, Taïeb A, Bickers DR, Mazurier F.

Nucleic Acids Res. 2010 Jan;38(3):797-809. doi: 10.1093/nar/gkp1072. Epub 2009 Nov 24.

30.

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms.

Athar M, Back JH, Kopelovich L, Bickers DR, Kim AL.

Arch Biochem Biophys. 2009 Jun 15;486(2):95-102. Review.

31.

Expression and function of cytochrome p450-dependent enzymes in human skin cells.

Baron JM, Wiederholt T, Heise R, Merk HF, Bickers DR.

Curr Med Chem. 2008;15(22):2258-64. Review.

PMID:
18781947
32.

Effects of photodynamic therapy evaluated in a novel three-dimensional squamous cell carcinoma organ construct of the skin.

Obrigkeit DH, Jugert FK, Beermann T, Baron JM, Frank J, Merk HF, Bickers DR, Abuzahra F.

Photochem Photobiol. 2009 Jan-Feb;85(1):272-8. doi: 10.1111/j.1751-1097.2008.00432.x. Epub 2008 Aug 27.

PMID:
18764893
33.

Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice.

Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M.

Photochem Photobiol. 2008 Mar-Apr;84(2):522-7. doi: 10.1111/j.1751-1097.2008.00303.x. Epub 2008 Feb 2.

PMID:
18266822
34.

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, Bickers DR, Athar M.

J Clin Invest. 2007 Dec;117(12):3753-64.

35.

Resveratrol: a review of preclinical studies for human cancer prevention.

Athar M, Back JH, Tang X, Kim KH, Kopelovich L, Bickers DR, Kim AL.

Toxicol Appl Pharmacol. 2007 Nov 1;224(3):274-83. Epub 2007 Jan 3. Review.

36.

Oxidative stress in the pathogenesis of skin disease.

Bickers DR, Athar M.

J Invest Dermatol. 2006 Dec;126(12):2565-75. Review.

37.

The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology.

Bickers DR, Lim HW, Margolis D, Weinstock MA, Goodman C, Faulkner E, Gould C, Gemmen E, Dall T; American Academy of Dermatology Association; Society for Investigative Dermatology.

J Am Acad Dermatol. 2006 Sep;55(3):490-500.

PMID:
16908356
38.
39.

Skin retinoid concentrations are modulated by CYP26AI expression restricted to basal keratinocytes in normal human skin and differentiated 3D skin models.

Heise R, Mey J, Neis MM, Marquardt Y, Joussen S, Ott H, Wiederholt T, Kurschat P, Megahed M, Bickers DR, Merk HF, Baron JM.

J Invest Dermatol. 2006 Nov;126(11):2473-80. Epub 2006 Jun 15.

40.

Resveratrol inhibits proliferation of human epidermoid carcinoma A431 cells by modulating MEK1 and AP-1 signalling pathways.

Kim AL, Zhu Y, Zhu H, Han L, Kopelovich L, Bickers DR, Athar M.

Exp Dermatol. 2006 Jul;15(7):538-46.

PMID:
16761963
41.

Refractory eczematous dermatitis associated with retained suture material.

Ascherman JA, Hunter CJ, Bickers DR.

Ann Plast Surg. 2006 Feb;56(2):205-7.

PMID:
16432334
42.

Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer.

Lee JL, Kim A, Kopelovich L, Bickers DR, Athar M.

J Invest Dermatol. 2005 Oct;125(4):818-25.

43.

Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro.

Baron JM, Heise R, Blaner WS, Neis M, Joussen S, Dreuw A, Marquardt Y, Saurat JH, Merk HF, Bickers DR, Jugert FK.

J Invest Dermatol. 2005 Jul;125(1):143-53.

44.

Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice.

Kim AL, Labasi JM, Zhu Y, Tang X, McClure K, Gabel CA, Athar M, Bickers DR.

J Invest Dermatol. 2005 Jun;124(6):1318-25. Erratum in: J Invest Dermatol. 2005 Dec;125(6):1320.

45.

Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.

Athar M, Li C, Tang X, Chi S, Zhang X, Kim AL, Tyring SK, Kopelovich L, Hebert J, Epstein EH Jr, Bickers DR, Xie J.

Cancer Res. 2004 Oct 15;64(20):7545-52.

46.

Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.

Tang X, Kim AL, Feith DJ, Pegg AE, Russo J, Zhang H, Aszterbaum M, Kopelovich L, Epstein EH Jr, Bickers DR, Athar M.

J Clin Invest. 2004 Mar;113(6):867-75.

47.

Immunoprevention of basal cell carcinomas with recombinant hedgehog-interacting protein.

Vogt A, Chuang PT, Hebert J, Hwang J, Lu Y, Kopelovich L, Athar M, Bickers DR, Epstein EH Jr.

J Exp Med. 2004 Mar 15;199(6):753-61.

48.

Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.

Athar M, An KP, Tang X, Morel KD, Kim AL, Kopelovich L, Bickers DR.

Toxicol Appl Pharmacol. 2004 Mar 15;195(3):370-8.

PMID:
15020200
49.

Considerations for testing irritancy, allergy, and photoreactivity in fragrance safety evaluations.

Hanifin JM, Api AM, Bickers DR.

Am J Contact Dermat. 2003 Jun;14(2):100-3.

PMID:
14749031
50.

Multiple patch-test reactions: a pilot evaluation of a combination approach to visualize patterns of multiple sensitivity in patch-test databases and a proposal for a multiple sensitivity index.

Dickel H, Taylor JS, Bickers DR, Merk HF, Bruckner TM.

Am J Contact Dermat. 2003 Sep;14(3):148-53. Erratum in: Am J Contact Dermat. 2003 Dec;14(4):224.

PMID:
14744406

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