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Items: 1 to 50 of 57

1.

Candida auris outbreak on a vascular ward - the unexpected arrival of an anticipated pathogen.

O'Connor C, Bicanic T, Dave J, Evans TJ, Moxey P, Adamu U, Shakespeare D, Cotter M.

J Hosp Infect. 2019 Sep;103(1):106-108. doi: 10.1016/j.jhin.2019.06.002. Epub 2019 Jun 17. No abstract available.

PMID:
31220481
2.

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis.

Stone NR, Rhodes J, Fisher MC, Mfinanga S, Kivuyo S, Rugemalila J, Segal ES, Needleman L, Molloy SF, Kwon-Chung J, Harrison TS, Hope W, Berman J, Bicanic T.

J Clin Invest. 2019 Mar 1;129(3):999-1014. doi: 10.1172/JCI124516. Epub 2019 Jan 28.

3.

Transcriptional Profiling of Patient Isolates Identifies a Novel TOR/Starvation Regulatory Pathway in Cryptococcal Virulence.

Park YD, Jarvis JN, Hu G, Davis SE, Qiu J, Zhang N, Hollingsworth C, Loyse A, Gardina PJ, Valyi-Nagy T, Myers TG, Harrison TS, Bicanic T, Williamson PR.

MBio. 2018 Dec 18;9(6). pii: e02353-18. doi: 10.1128/mBio.02353-18.

4.

Effectiveness of an antifungal stewardship programme at a London teaching hospital 2010-16.

Whitney L, Al-Ghusein H, Glass S, Koh M, Klammer M, Ball J, Youngs J, Wake R, Houston A, Bicanic T.

J Antimicrob Chemother. 2019 Jan 1;74(1):234-241. doi: 10.1093/jac/dky389.

PMID:
30376118
5.

Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries.

Loyse A, Burry J, Cohn J, Ford N, Chiller T, Ribeiro I, Koulla-Shiro S, Mghamba J, Ramadhani A, Nyirenda R, Aliyu SH, Wilson D, Le T, Oladele R, Lesikari S, Muzoora C, Kalata N, Temfack E, Mapoure Y, Sini V, Chanda D, Shimwela M, Lakhi S, Ngoma J, Gondwe-Chunda L, Perfect C, Shroufi A, Andrieux-Meyer I, Chan A, Schutz C, Hosseinipour M, Van der Horst C, Klausner JD, Boulware DR, Heyderman R, Lalloo D, Day J, Jarvis JN, Rodrigues M, Jaffar S, Denning D, Migone C, Doherty M, Lortholary O, Dromer F, Stack M, Molloy SF, Bicanic T, van Oosterhout J, Mwaba P, Kanyama C, Kouanfack C, Mfinanga S, Govender N, Harrison TS.

Lancet Infect Dis. 2019 Apr;19(4):e143-e147. doi: 10.1016/S1473-3099(18)30493-6. Epub 2018 Oct 18. Review.

PMID:
30344084
6.

Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis.

Eshun-Wilson I, Okwen MP, Richardson M, Bicanic T.

Cochrane Database Syst Rev. 2018 Jul 24;7:CD009012. doi: 10.1002/14651858.CD009012.pub3. Review.

7.

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis.

Dambuza IM, Drake T, Chapuis A, Zhou X, Correia J, Taylor-Smith L, LeGrave N, Rasmussen T, Fisher MC, Bicanic T, Harrison TS, Jaspars M, May RC, Brown GD, Yuecel R, MacCallum DM, Ballou ER.

PLoS Pathog. 2018 May 18;14(5):e1006978. doi: 10.1371/journal.ppat.1006978. eCollection 2018 May.

8.

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

Molloy SF, Kanyama C, Heyderman RS, Loyse A, Kouanfack C, Chanda D, Mfinanga S, Temfack E, Lakhi S, Lesikari S, Chan AK, Stone N, Kalata N, Karunaharan N, Gaskell K, Peirse M, Ellis J, Chawinga C, Lontsi S, Ndong JG, Bright P, Lupiya D, Chen T, Bradley J, Adams J, van der Horst C, van Oosterhout JJ, Sini V, Mapoure YN, Mwaba P, Bicanic T, Lalloo DG, Wang D, Hosseinipour MC, Lortholary O, Jaffar S, Harrison TS; ACTA Trial Study Team.

N Engl J Med. 2018 Mar 15;378(11):1004-1017. doi: 10.1056/NEJMoa1710922.

9.

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level.

Rhodes J, Desjardins CA, Sykes SM, Beale MA, Vanhove M, Sakthikumar S, Chen Y, Gujja S, Saif S, Chowdhary A, Lawson DJ, Ponzio V, Colombo AL, Meyer W, Engelthaler DM, Hagen F, Illnait-Zaragozi MT, Alanio A, Vreulink JM, Heitman J, Perfect JR, Litvintseva AP, Bicanic T, Harrison TS, Fisher MC, Cuomo CA.

Genetics. 2017 Sep;207(1):327-346. doi: 10.1534/genetics.117.203836. Epub 2017 Jul 5.

10.

Cryptococcal meningitis: A neglected NTD?

Molloy SF, Chiller T, Greene GS, Burry J, Govender NP, Kanyama C, Mfinanga S, Lesikari S, Mapoure YN, Kouanfack C, Sini V, Temfack E, Boulware DR, Dromer F, Denning DW, Day J, Stone NRH, Bicanic T, Jarvis JN, Lortholary O, Harrison TS, Jaffar S, Loyse A.

PLoS Negl Trop Dis. 2017 Jun 29;11(6):e0005575. doi: 10.1371/journal.pntd.0005575. eCollection 2017 Jun. No abstract available.

11.

AIDS-Related Mycoses: Current Progress in the Field and Future Priorities.

Armstrong-James D, Bicanic T, Brown GD, Hoving JC, Meintjes G, Nielsen K; Working Group from the EMBO Workshop on AIDS-Related Mycoses.

Trends Microbiol. 2017 Jun;25(6):428-430. doi: 10.1016/j.tim.2017.02.013. Epub 2017 Apr 25.

PMID:
28454846
12.

A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection.

Rhodes J, Beale MA, Vanhove M, Jarvis JN, Kannambath S, Simpson JA, Ryan A, Meintjes G, Harrison TS, Fisher MC, Bicanic T.

G3 (Bethesda). 2017 Apr 3;7(4):1165-1176. doi: 10.1534/g3.116.037499.

13.

The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.

Kwon-Chung KJ, Bennett JE, Wickes BL, Meyer W, Cuomo CA, Wollenburg KR, Bicanic TA, Castañeda E, Chang YC, Chen J, Cogliati M, Dromer F, Ellis D, Filler SG, Fisher MC, Harrison TS, Holland SM, Kohno S, Kronstad JW, Lazera M, Levitz SM, Lionakis MS, May RC, Ngamskulrongroj P, Pappas PG, Perfect JR, Rickerts V, Sorrell TC, Walsh TJ, Williamson PR, Xu J, Zelazny AM, Casadevall A.

mSphere. 2017 Jan 11;2(1). pii: e00357-16. doi: 10.1128/mSphere.00357-16. eCollection 2017 Jan-Feb.

14.

Genomic epidemiology of Cryptococcus yeasts identifies adaptation to environmental niches underpinning infection across an African HIV/AIDS cohort.

Vanhove M, Beale MA, Rhodes J, Chanda D, Lakhi S, Kwenda G, Molloy S, Karunaharan N, Stone N, Harrison TS, Bicanic T, Fisher MC.

Mol Ecol. 2017 Apr;26(7):1991-2005. doi: 10.1111/mec.13891. Epub 2016 Nov 8.

15.

Liposomal Amphotericin B (AmBisome(®)): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions.

Stone NR, Bicanic T, Salim R, Hope W.

Drugs. 2016 Mar;76(4):485-500. doi: 10.1007/s40265-016-0538-7. Review.

16.

Reproducibility of CSF quantitative culture methods for estimating rate of clearance in cryptococcal meningitis.

Dyal J, Akampurira A, Rhein J, Morawski BM, Kiggundu R, Nabeta HW, Musubire AK, Bahr NC, Williams DA, Bicanic T, Larsen RA, Meya DB, Boulware DR; ASTRO-CM Trial Team.

Med Mycol. 2016 May;54(4):361-9. doi: 10.1093/mmy/myv104. Epub 2016 Jan 14.

17.

Cryptococcus: from environmental saprophyte to global pathogen.

May RC, Stone NR, Wiesner DL, Bicanic T, Nielsen K.

Nat Rev Microbiol. 2016 Feb;14(2):106-17. doi: 10.1038/nrmicro.2015.6. Epub 2015 Dec 21. Review.

18.

Toxicity of Amphotericin B Deoxycholate-Based Induction Therapy in Patients with HIV-Associated Cryptococcal Meningitis.

Bicanic T, Bottomley C, Loyse A, Brouwer AE, Muzoora C, Taseera K, Jackson A, Phulusa J, Hosseinipour MC, van der Horst C, Limmathurotsakul D, White NJ, Wilson D, Wood R, Meintjes G, Harrison TS, Jarvis JN.

Antimicrob Agents Chemother. 2015 Dec;59(12):7224-31. doi: 10.1128/AAC.01698-15. Epub 2015 Sep 8.

19.

Genotypic Diversity Is Associated with Clinical Outcome and Phenotype in Cryptococcal Meningitis across Southern Africa.

Beale MA, Sabiiti W, Robertson EJ, Fuentes-Cabrejo KM, O'Hanlon SJ, Jarvis JN, Loyse A, Meintjes G, Harrison TS, May RC, Fisher MC, Bicanic T.

PLoS Negl Trop Dis. 2015 Jun 25;9(6):e0003847. doi: 10.1371/journal.pntd.0003847. eCollection 2015.

20.

Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis.

Jarvis JN, Meintjes G, Bicanic T, Buffa V, Hogan L, Mo S, Tomlinson G, Kropf P, Noursadeghi M, Harrison TS.

PLoS Pathog. 2015 Apr 8;11(4):e1004754. doi: 10.1371/journal.ppat.1004754. eCollection 2015 Apr.

21.

Microrheology with optical tweezers: measuring the relative viscosity of solutions 'at a glance'.

Tassieri M, Del Giudice F, Robertson EJ, Jain N, Fries B, Wilson R, Glidle A, Greco F, Netti PA, Maffettone PL, Bicanic T, Cooper JM.

Sci Rep. 2015 Mar 6;5:8831. doi: 10.1038/srep08831.

22.

Neurological, visual, and MRI brain scan findings in 87 South African patients with HIV-associated cryptococcal meningoencephalitis.

Loyse A, Moodley A, Rich P, Molloy SF, Bicanic T, Bishop L, Rae WI, Bhigjee AI, Loubser ND, Michowicz AJ, Wilson D, Harrison TS.

J Infect. 2015 Jun;70(6):668-75. doi: 10.1016/j.jinf.2014.10.007. Epub 2014 Oct 22.

PMID:
25444972
23.

Treatment principles for Candida and Cryptococcus.

Whitney LC, Bicanic T.

Cold Spring Harb Perspect Med. 2014 Nov 10;5(6). pii: a024158. doi: 10.1101/cshperspect.a024158. Review.

24.

Cryptococcosis diagnosis and treatment: What do we know now.

Perfect JR, Bicanic T.

Fungal Genet Biol. 2015 May;78:49-54. doi: 10.1016/j.fgb.2014.10.003. Epub 2014 Oct 13. Review.

25.

Very low levels of 25-hydroxyvitamin D are not associated with immunologic changes or clinical outcome in South African patients with HIV-associated cryptococcal meningitis.

Jarvis JN, Bicanic T, Loyse A, Meintjes G, Hogan L, Roberts CH, Shoham S, Perfect JR, Govender NP, Harrison TS.

Clin Infect Dis. 2014 Aug 15;59(4):493-500. doi: 10.1093/cid/ciu349. Epub 2014 May 13.

26.

Access to antifungal medicines in resource-poor countries - authors' reply.

Loyse A, Thangaraj H, Govender NP, Harrison T, Bicanic T; all authors.

Lancet Infect Dis. 2014 May;14(5):371. doi: 10.1016/S1473-3099(14)70068-4. No abstract available.

PMID:
24758994
27.

Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis.

Sabiiti W, Robertson E, Beale MA, Johnston SA, Brouwer AE, Loyse A, Jarvis JN, Gilbert AS, Fisher MC, Harrison TS, May RC, Bicanic T.

J Clin Invest. 2014 May;124(5):2000-8. doi: 10.1172/JCI72950. Epub 2014 Apr 17.

28.

AIDS-related mycoses: the way forward.

Brown GD, Meintjes G, Kolls JK, Gray C, Horsnell W; Working Group from the EMBO-AIDS Related Mycoses Workshop, Achan B, Alber G, Aloisi M, Armstrong-James D, Beale M, Bicanic T, Black J, Bohjanen P, Botes A, Boulware DR, Brown G, Bunjun R, Carr W, Casadevall A, Chang C, Chivero E, Corcoran C, Cross A, Dawood H, Day J, De Bernardis F, De Jager V, De Repentigny L, Denning D, Eschke M, Finkelman M, Govender N, Gow N, Graham L, Gryschek R, Hammond-Aryee K, Harrison T, Heard N, Hill M, Hoving JC, Janoff E, Jarvis J, Kayuni S, King K, Kolls J, Kullberg BJ, Lalloo DG, Letang E, Levitz S, Limper A, Longley N, Machiridza TR, Mahabeer Y, Martinsons N, Meiring S, Meya D, Miller R, Molloy S, Morris L, Mukaremera L, Musubire AK, Muzoora C, Nair A, Nakiwala Kimbowa J, Netea M, Nielsen K, O'hern J, Okurut S, Parker A, Patterson T, Pennap G, Perfect J, Prinsloo C, Rhein J, Rolfes MA, Samuel C, Schutz C, Scriven J, Sebolai OM, Sojane K, Sriruttan C, Stead D, Steyn A, Thawer NK, Thienemann F, Von Hohenberg M, Vreulink JM, Wessels J, Wood K, Yang YL.

Trends Microbiol. 2014 Mar;22(3):107-9. doi: 10.1016/j.tim.2013.12.008.

29.

The Cryptococcus neoformans transcriptome at the site of human meningitis.

Chen Y, Toffaletti DL, Tenor JL, Litvintseva AP, Fang C, Mitchell TG, McDonald TR, Nielsen K, Boulware DR, Bicanic T, Perfect JR.

MBio. 2014 Feb 4;5(1):e01087-13. doi: 10.1128/mBio.01087-13.

30.

Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes.

Jarvis JN, Bicanic T, Loyse A, Namarika D, Jackson A, Nussbaum JC, Longley N, Muzoora C, Phulusa J, Taseera K, Kanyembe C, Wilson D, Hosseinipour MC, Brouwer AE, Limmathurotsakul D, White N, van der Horst C, Wood R, Meintjes G, Bradley J, Jaffar S, Harrison T.

Clin Infect Dis. 2014 Mar;58(5):736-45. doi: 10.1093/cid/cit794. Epub 2013 Dec 6.

31.

Cryptococcus neoformans ex vivo capsule size is associated with intracranial pressure and host immune response in HIV-associated cryptococcal meningitis.

Robertson EJ, Najjuka G, Rolfes MA, Akampurira A, Jain N, Anantharanjit J, von Hohenberg M, Tassieri M, Carlsson A, Meya DB, Harrison TS, Fries BC, Boulware DR, Bicanic T.

J Infect Dis. 2014 Jan 1;209(1):74-82. doi: 10.1093/infdis/jit435. Epub 2013 Aug 14.

32.

Combination antifungal therapy for cryptococcal meningitis.

Loyse A, Bicanic T, Jarvis JN.

N Engl J Med. 2013 Jun 27;368(26):2522. doi: 10.1056/NEJMc1305981. No abstract available.

33.

Cryptococcal meningitis: improving access to essential antifungal medicines in resource-poor countries.

Loyse A, Thangaraj H, Easterbrook P, Ford N, Roy M, Chiller T, Govender N, Harrison TS, Bicanic T.

Lancet Infect Dis. 2013 Jul;13(7):629-37. doi: 10.1016/S1473-3099(13)70078-1. Epub 2013 Jun 2. Review.

PMID:
23735626
34.

British HIV Association opportunistic infection guidelines: in defence of amphotericin B deoxycholate.

Bicanic T, Ogden D, Whitney L, Loyse A, Jarvis J.

HIV Med. 2012 Nov;13(10):636-7. doi: 10.1111/j.1468-1293.2012.01022.x. No abstract available.

35.

The prevalence of cryptococcal antigenemia in newly diagnosed HIV patients in a Southwest London cohort.

Patel S, Shin GY, Wijewardana I, Vitharana SR, Cormack I, Pakianathan M, Harrison TS, Bicanic T.

J Infect. 2013 Jan;66(1):75-9. doi: 10.1016/j.jinf.2012.09.014. Epub 2012 Oct 6.

36.

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial.

Jarvis JN, Meintjes G, Rebe K, Williams GN, Bicanic T, Williams A, Schutz C, Bekker LG, Wood R, Harrison TS.

AIDS. 2012 Jun 1;26(9):1105-13. doi: 10.1097/QAD.0b013e3283536a93.

37.

Comparison of the early fungicidal activity of high-dose fluconazole, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for the treatment of HIV-associated cryptococcal meningitis.

Loyse A, Wilson D, Meintjes G, Jarvis JN, Bicanic T, Bishop L, Rebe K, Williams A, Jaffar S, Bekker LG, Wood R, Harrison TS.

Clin Infect Dis. 2012 Jan 1;54(1):121-8. doi: 10.1093/cid/cir745. Epub 2011 Nov 3.

PMID:
22052885
38.

Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients.

Hu G, Wang J, Choi J, Jung WH, Liu I, Litvintseva AP, Bicanic T, Aurora R, Mitchell TG, Perfect JR, Kronstad JW.

BMC Genomics. 2011 Oct 27;12:526. doi: 10.1186/1471-2164-12-526.

39.

Large volume lumbar punctures in cryptococcal meningitis clear cryptococcal antigen as well as lowering pressure.

Wijewardana I, Jarvis JN, Meintjes G, Harrison TS, Bicanic T.

J Infect. 2011 Dec;63(6):484-6. doi: 10.1016/j.jinf.2011.09.002. Epub 2011 Sep 14. No abstract available.

PMID:
21930156
40.

Routine cryptococcal antigen screening for HIV-infected patients with low CD4+ T-lymphocyte counts--time to implement in South Africa?

Jarvis JN, Harrison TS, Govender N, Lawn SD, Longley N, Bicanic T, Maartens G, Venter F, Bekker LG, Wood R, Meintjes G.

S Afr Med J. 2011 Apr;101(4):232-4. No abstract available.

PMID:
21786721
41.

Should antiretroviral therapy be delayed for 10 weeks for patients treated with fluconazole for cryptococcal meningitis?

Bicanic T, Jarvis JN, Muzoora C, Harrison TS.

Clin Infect Dis. 2010 Oct 15;51(8):986-7; author reply 987-9. doi: 10.1086/656437. No abstract available.

PMID:
20858077
42.

Positive predictive value of the UK clinical case definition for H1N1/09 ('swine') influenza.

Bicanic T, Solomon AW, Karunaharan N, Chua F, Pope C, Pond M, Herman J, Loyse A, Harrison T, Wansbrough-Jones M.

J Infect. 2010 May;60(5):405-7. doi: 10.1016/j.jinf.2010.02.001. Epub 2010 Feb 7. No abstract available.

PMID:
20144897
43.

Histopathology of the arachnoid granulations and brain in HIV-associated cryptococcal meningitis: correlation with cerebrospinal fluid pressure.

Loyse A, Wainwright H, Jarvis JN, Bicanic T, Rebe K, Meintjes G, Harrison TS.

AIDS. 2010 Jan 28;24(3):405-10. doi: 10.1097/QAD.0b013e328333c005.

44.

Independent association between rate of clearance of infection and clinical outcome of HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients.

Bicanic T, Muzoora C, Brouwer AE, Meintjes G, Longley N, Taseera K, Rebe K, Loyse A, Jarvis J, Bekker LG, Wood R, Limmathurotsakul D, Chierakul W, Stepniewska K, White NJ, Jaffar S, Harrison TS.

Clin Infect Dis. 2009 Sep 1;49(5):702-9. doi: 10.1086/604716.

45.

High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out.

Jarvis JN, Boulle A, Loyse A, Bicanic T, Rebe K, Williams A, Harrison TS, Meintjes G.

AIDS. 2009 Jun 1;23(9):1182-3. doi: 10.1097/QAD.0b013e32832be0fc. No abstract available.

46.

Immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis: a prospective study.

Bicanic T, Meintjes G, Rebe K, Williams A, Loyse A, Wood R, Hayes M, Jaffar S, Harrison T.

J Acquir Immune Defic Syndr. 2009 Jun 1;51(2):130-4. doi: 10.1097/QAI.0b013e3181a56f2e.

PMID:
19365271
47.

Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures.

Bicanic T, Brouwer AE, Meintjes G, Rebe K, Limmathurotsakul D, Chierakul W, Teparrakkul P, Loyse A, White NJ, Wood R, Jaffar S, Harrison T.

AIDS. 2009 Mar 27;23(6):701-6. doi: 10.1097/QAD.0b013e32832605fe.

PMID:
19279443
48.

High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial.

Bicanic T, Wood R, Meintjes G, Rebe K, Brouwer A, Loyse A, Bekker LG, Jaffar S, Harrison T.

Clin Infect Dis. 2008 Jul 1;47(1):123-30. doi: 10.1086/588792.

PMID:
18505387
49.

Lymphatic abnormalities demonstrated by lymphoscintigraphy after lower limb cellulitis.

Soo JK, Bicanic TA, Heenan S, Mortimer PS.

Br J Dermatol. 2008 Jun;158(6):1350-3. doi: 10.1111/j.1365-2133.2007.08423.x. Epub 2008 Jan 30.

PMID:
18241266
50.

Fungal burden, early fungicidal activity, and outcome in cryptococcal meningitis in antiretroviral-naive or antiretroviral-experienced patients treated with amphotericin B or fluconazole.

Bicanic T, Meintjes G, Wood R, Hayes M, Rebe K, Bekker LG, Harrison T.

Clin Infect Dis. 2007 Jul 1;45(1):76-80. Epub 2007 May 25. Erratum in: Clin Infect Dis. 2007 Aug 15;45(4):526.

PMID:
17554704

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