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Items: 1 to 50 of 190

1.

c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces.

Gallagher KA, Schumacher MA, Bush MJ, Bibb MJ, Chandra G, Holmes NA, Zeng W, Henderson M, Zhang H, Findlay KC, Brennan RG, Buttner MJ.

Mol Cell. 2019 Nov 27. pii: S1097-2765(19)30835-4. doi: 10.1016/j.molcel.2019.11.006. [Epub ahead of print]

PMID:
31810759
2.

In situ activation and heterologous production of a cryptic lantibiotic from a plant-ant derived Saccharopolyspora species.

Vikeli E, Widdick DA, Batey SF, Heine D, Holmes NA, Bibb MJ, Martins DJ, Pierce NE, Hutchings MI, Wilkinson B.

Appl Environ Microbiol. 2019 Nov 15. pii: AEM.01876-19. doi: 10.1128/AEM.01876-19. [Epub ahead of print]

3.

Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34T Yields a Novel Lasso Peptide, Leepeptin.

Gomez-Escribano JP, Castro JF, Razmilic V, Jarmusch SA, Saalbach G, Ebel R, Jaspars M, Andrews B, Asenjo JA, Bibb MJ.

Appl Environ Microbiol. 2019 Nov 14;85(23). pii: e01752-19. doi: 10.1128/AEM.01752-19. Print 2019 Dec 1.

4.

Defining the regulon of genes controlled by σE , a key regulator of the cell envelope stress response in Streptomyces coelicolor.

Tran NT, Huang X, Hong HJ, Bush MJ, Chandra G, Pinto D, Bibb MJ, Hutchings MI, Mascher T, Buttner MJ.

Mol Microbiol. 2019 Aug;112(2):461-481. doi: 10.1111/mmi.14250. Epub 2019 Apr 29.

5.

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.

Dong YY, Wang H, Pike ACW, Cochrane SA, Hamedzadeh S, Wyszyński FJ, Bushell SR, Royer SF, Widdick DA, Sajid A, Boshoff HI, Park Y, Lucas R, Liu WM, Lee SS, Machida T, Minall L, Mehmood S, Belaya K, Liu WW, Chu A, Shrestha L, Mukhopadhyay SMM, Strain-Damerell C, Chalk R, Burgess-Brown NA, Bibb MJ, Barry Iii CE, Robinson CV, Beeson D, Davis BG, Carpenter EP.

Cell. 2018 Nov 1;175(4):1045-1058.e16. doi: 10.1016/j.cell.2018.10.037.

6.

The crystal structure of the RsbN-σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor.

Schumacher MA, Bush MJ, Bibb MJ, Ramos-León F, Chandra G, Zeng W, Buttner MJ.

Nucleic Acids Res. 2018 Aug 21;46(14):7467-7468. doi: 10.1093/nar/gky616. No abstract available.

7.

The crystal structure of the RsbN-σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor.

Schumacher MA, Bush MJ, Bibb MJ, Ramos-León F, Chandra G, Zeng W, Buttner MJ.

Nucleic Acids Res. 2018 Aug 21;46(14):7405-7417. doi: 10.1093/nar/gky493. Erratum in: Nucleic Acids Res. 2018 Aug 21;46(14):7467-7468.

8.

Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity.

Widdick D, Royer SF, Wang H, Vior NM, Gomez-Escribano JP, Davis BG, Bibb MJ.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00130-18. doi: 10.1128/AAC.00130-18. Print 2018 Aug.

9.

The 'gifted' actinomycete Streptomyces leeuwenhoekii.

Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo J, Bibb M.

Antonie Van Leeuwenhoek. 2018 Aug;111(8):1433-1448. doi: 10.1007/s10482-018-1034-8. Epub 2018 Feb 3. Review.

PMID:
29397490
10.

Two dynamin-like proteins stabilize FtsZ rings during Streptomyces sporulation.

Schlimpert S, Wasserstrom S, Chandra G, Bibb MJ, Findlay KC, Flärdh K, Buttner MJ.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6176-E6183. doi: 10.1073/pnas.1704612114. Epub 2017 Jul 7.

11.

Watasemycin biosynthesis in Streptomyces venezuelae: thiazoline C-methylation by a type B radical-SAM methylase homologue.

Inahashi Y, Zhou S, Bibb MJ, Song L, Al-Bassam MM, Bibb MJ, Challis GL.

Chem Sci. 2017 Apr 1;8(4):2823-2831. doi: 10.1039/c6sc03533g. Epub 2017 Jan 19.

12.

A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646.

O'Rourke S, Widdick D, Bibb M.

J Ind Microbiol Biotechnol. 2017 May;44(4-5):563-572. doi: 10.1007/s10295-016-1869-9. Epub 2016 Nov 17.

13.

Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster.

Thanapipatsiri A, Gomez-Escribano JP, Song L, Bibb MJ, Al-Bassam M, Chandra G, Thamchaipenet A, Challis GL, Bibb MJ.

Chembiochem. 2016 Nov 17;17(22):2189-2198. doi: 10.1002/cbic.201600396. Epub 2016 Oct 13.

14.

Developmental delay in a Streptomyces venezuelae glgE null mutant is associated with the accumulation of α-maltose 1-phosphate.

Miah F, Bibb MJ, Barclay JE, Findlay KC, Bornemann S.

Microbiology. 2016 Jul;162(7):1208-1219. doi: 10.1099/mic.0.000296. Epub 2016 Apr 26.

16.

Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural Products.

Gomez-Escribano JP, Alt S, Bibb MJ.

Mar Drugs. 2016 Apr 13;14(4). pii: E78. doi: 10.3390/md14040078. Review.

17.

A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes.

Thanapipatsiri A, Claesen J, Gomez-Escribano JP, Bibb M, Thamchaipenet A.

Microb Cell Fact. 2015 Sep 16;14:145. doi: 10.1186/s12934-015-0335-0.

18.

Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate.

Rateb ME, Zhai Y, Ehrner E, Rath CM, Wang X, Tabudravu J, Ebel R, Bibb M, Kyeremeh K, Dorrestein PC, Hong K, Jaspars M, Deng H.

Org Biomol Chem. 2015 Oct 7;13(37):9585-92. doi: 10.1039/c5ob01269d.

PMID:
26256511
19.

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2.

Gomez-Escribano JP, Castro JF, Razmilic V, Chandra G, Andrews B, Asenjo JA, Bibb MJ.

BMC Genomics. 2015 Jun 30;16:485. doi: 10.1186/s12864-015-1652-8.

20.

Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii.

Castro JF, Razmilic V, Gomez-Escribano JP, Andrews B, Asenjo JA, Bibb MJ.

Appl Environ Microbiol. 2015 Sep 1;81(17):5820-31. doi: 10.1128/AEM.01039-15. Epub 2015 Jun 19.

21.

Two Master Switch Regulators Trigger A40926 Biosynthesis in Nonomuraea sp. Strain ATCC 39727.

Lo Grasso L, Maffioli S, Sosio M, Bibb M, Puglia AM, Alduina R.

J Bacteriol. 2015 Aug 1;197(15):2536-44. doi: 10.1128/JB.00262-15. Epub 2015 May 18.

22.

A relA-dependent regulatory cascade for auto-induction of microbisporicin production in Microbispora corallina.

Fernández-Martínez LT, Gomez-Escribano JP, Bibb MJ.

Mol Microbiol. 2015 Aug;97(3):502-14. doi: 10.1111/mmi.13046. Epub 2015 May 29.

23.

Use of the meganuclease I-SceI of Saccharomyces cerevisiae to select for gene deletions in actinomycetes.

Fernández-Martínez LT, Bibb MJ.

Sci Rep. 2014 Nov 18;4:7100. doi: 10.1038/srep07100.

24.

New insights into chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712.

Fernández-Martínez LT, Borsetto C, Gomez-Escribano JP, Bibb MJ, Al-Bassam MM, Chandra G, Bibb MJ.

Antimicrob Agents Chemother. 2014 Dec;58(12):7441-50. doi: 10.1128/AAC.04272-14. Epub 2014 Sep 29.

25.

Response regulator heterodimer formation controls a key stage in Streptomyces development.

Al-Bassam MM, Bibb MJ, Bush MJ, Chandra G, Buttner MJ.

PLoS Genet. 2014 Aug 7;10(8):e1004554. doi: 10.1371/journal.pgen.1004554. eCollection 2014 Aug.

26.

Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727.

Marcone GL, Binda E, Carrano L, Bibb M, Marinelli F.

Antimicrob Agents Chemother. 2014 Sep;58(9):5191-201. doi: 10.1128/AAC.02626-14. Epub 2014 Jun 23.

27.

Understanding and manipulating antibiotic production in actinomycetes.

Bibb MJ.

Biochem Soc Trans. 2013 Dec;41(6):1355-64. doi: 10.1042/BST20130214. Review.

PMID:
24256223
28.

Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways.

Gomez-Escribano JP, Bibb MJ.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):425-31. doi: 10.1007/s10295-013-1348-5. Epub 2013 Oct 6. Review.

PMID:
24096958
29.

Genes required for aerial growth, cell division, and chromosome segregation are targets of WhiA before sporulation in Streptomyces venezuelae.

Bush MJ, Bibb MJ, Chandra G, Findlay KC, Buttner MJ.

MBio. 2013 Sep 24;4(5):e00684-13. doi: 10.1128/mBio.00684-13.

30.

Evolutionary relationships among actinophages and a putative adaptation for growth in Streptomyces spp.

Smith MC, Hendrix RW, Dedrick R, Mitchell K, Ko CC, Russell D, Bell E, Gregory M, Bibb MJ, Pethick F, Jacobs-Sera D, Herron P, Buttner MJ, Hatfull GF.

J Bacteriol. 2013 Nov;195(21):4924-35. doi: 10.1128/JB.00618-13. Epub 2013 Aug 30.

31.

Phage p1-derived artificial chromosomes facilitate heterologous expression of the FK506 gene cluster.

Jones AC, Gust B, Kulik A, Heide L, Buttner MJ, Bibb MJ.

PLoS One. 2013 Jul 11;8(7):e69319. doi: 10.1371/journal.pone.0069319. Print 2013.

32.

Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2).

Uguru GC, Mondhe M, Goh S, Hesketh A, Bibb MJ, Good L, Stach JE.

PLoS One. 2013 Jun 27;8(6):e67509. doi: 10.1371/journal.pone.0067509. Print 2013.

33.

The antibiotic planosporicin coordinates its own production in the actinomycete Planomonospora alba.

Sherwood EJ, Bibb MJ.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2500-9. doi: 10.1073/pnas.1305392110. Epub 2013 Jun 17.

34.

Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography.

Stevenson CE, Assaad A, Chandra G, Le TB, Greive SJ, Bibb MJ, Lawson DM.

Nucleic Acids Res. 2013 Aug;41(14):7009-22. doi: 10.1093/nar/gkt523. Epub 2013 Jun 7.

35.

Cloning and analysis of the planosporicin lantibiotic biosynthetic gene cluster of Planomonospora alba.

Sherwood EJ, Hesketh AR, Bibb MJ.

J Bacteriol. 2013 May;195(10):2309-21. doi: 10.1128/JB.02291-12. Epub 2013 Mar 8.

36.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA.

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f. Review.

37.

Streptomyces coelicolor as an expression host for heterologous gene clusters.

Gomez-Escribano JP, Bibb MJ.

Methods Enzymol. 2012;517:279-300. doi: 10.1016/B978-0-12-404634-4.00014-0.

PMID:
23084944
38.

High resolution crystal structure of Sco5413, a widespread actinomycete MarR family transcriptional regulator of unknown function.

Holley TA, Stevenson CE, Bibb MJ, Lawson DM.

Proteins. 2013 Jan;81(1):176-82. doi: 10.1002/prot.24197. Epub 2012 Nov 5.

PMID:
23042442
39.

Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates.

Wyszynski FJ, Lee SS, Yabe T, Wang H, Gomez-Escribano JP, Bibb MJ, Lee SJ, Davies GJ, Davis BG.

Nat Chem. 2012 May 20;4(7):539-46. doi: 10.1038/nchem.1351.

PMID:
22717438
40.

Expression of the chaplin and rodlin hydrophobic sheath proteins in Streptomyces venezuelae is controlled by σ(BldN) and a cognate anti-sigma factor, RsbN.

Bibb MJ, Domonkos A, Chandra G, Buttner MJ.

Mol Microbiol. 2012 Jun;84(6):1033-49. doi: 10.1111/j.1365-2958.2012.08070.x. Epub 2012 May 14.

41.

A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor.

Murakami T, Burian J, Yanai K, Bibb MJ, Thompson CJ.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16020-5. doi: 10.1073/pnas.1108124108. Epub 2011 Sep 8.

42.

Draft genome sequence of Streptomyces strain S4, a symbiont of the leaf-cutting ant Acromyrmex octospinosus.

Seipke RF, Crossman L, Drou N, Heavens D, Bibb MJ, Caccamo M, Hutchings MI.

J Bacteriol. 2011 Aug;193(16):4270-1. doi: 10.1128/JB.05275-11. Epub 2011 Jun 17.

43.

Abyssomicin biosynthesis: formation of an unusual polyketide, antibiotic-feeding studies and genetic analysis.

Gottardi EM, Krawczyk JM, von Suchodoletz H, Schadt S, Mühlenweg A, Uguru GC, Pelzer S, Fiedler HP, Bibb MJ, Stach JE, Süssmuth RD.

Chembiochem. 2011 Jun 14;12(9):1401-10. doi: 10.1002/cbic.201100172. No abstract available.

44.

Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope.

Hesketh A, Hill C, Mokhtar J, Novotna G, Tran N, Bibb M, Hong HJ.

BMC Genomics. 2011 May 11;12:226. doi: 10.1186/1471-2164-12-226.

45.

Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.

Roh H, Uguru GC, Ko HJ, Kim S, Kim BY, Goodfellow M, Bull AT, Kim KH, Bibb MJ, Choi IG, Stach JE.

J Bacteriol. 2011 Jul;193(13):3391-2. doi: 10.1128/JB.05041-11. Epub 2011 May 6.

46.

Feed-forward regulation of microbisporicin biosynthesis in Microbispora corallina.

Foulston L, Bibb M.

J Bacteriol. 2011 Jun;193(12):3064-71. doi: 10.1128/JB.00250-11. Epub 2011 Apr 8.

47.

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.

Pullan ST, Chandra G, Bibb MJ, Merrick M.

BMC Genomics. 2011 Apr 4;12:175. doi: 10.1186/1471-2164-12-175.

48.
49.

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

Gomez-Escribano JP, Bibb MJ.

Microb Biotechnol. 2011 Mar;4(2):207-15. doi: 10.1111/j.1751-7915.2010.00219.x. Epub 2010 Oct 26.

50.

ZouA, a putative relaxase, is essential for dna amplification in Streptomyces kanamyceticus.

Murakami T, Sumida N, Bibb M, Yanai K.

J Bacteriol. 2011 Apr;193(8):1815-22. doi: 10.1128/JB.01325-10. Epub 2011 Feb 4.

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