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Access Sites for TAVI: Patient Selection Criteria, Technical Aspects, and Outcomes.

Biasco L, Ferrari E, Pedrazzini G, Faletra F, Moccetti T, Petracca F, Moccetti M.

Front Cardiovasc Med. 2018 Jul 17;5:88. doi: 10.3389/fcvm.2018.00088. eCollection 2018. Review.


Radiological exposure of patients undergoing transcatheter aortic valve implantation in contemporary practice.

Biasco L, Pedrazzini G, De Backer O, Klersy C, Bellesi L, Presilla S, Badini M, Faletra F, Pasotti E, Ferrari E, Demertzis S, Moccetti T, Aviano D, Moccetti M.

J Cardiovasc Med (Hagerstown). 2018 Oct;19(10):579-585. doi: 10.2459/JCM.0000000000000692.


Echocardiographic-fluoroscopic fusion imaging for transcatheter mitral valve repair guidance.

Faletra FF, Pozzoli A, Agricola E, Guidotti A, Biasco L, Leo LA, Taramasso M, Pasotti E, Kuwata S, Moccetti M, Tanner FC, Pedrazzini G, Nietlispach F, Moccetti T, Zuber M, Maisano F.

Eur Heart J Cardiovasc Imaging. 2018 Jul 1;19(7):715-726. doi: 10.1093/ehjci/jey067.


Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE.

Yadak R, Cabrera-Pérez R, Torres-Torronteras J, Bugiani M, Haeck JC, Huston MW, Bogaerts E, Goffart S, Jacobs EH, Stok M, Leonardelli L, Biasco L, Verdijk RM, Bernsen MR, Ruijter G, Martí R, Wagemaker G, van Til NP, de Coo IFM.

Mol Ther Methods Clin Dev. 2018 Jan 8;8:152-165. doi: 10.1016/j.omtm.2018.01.001. eCollection 2018 Mar 16.


New-onset or Pre-existing Atrial Fibrillation in Acute Coronary Syndromes: Two Distinct Phenomena With a Similar Prognosis.

Biasco L, Radovanovic D, Moccetti M, Rickli H, Roffi M, Eberli F, Jeger R, Moccetti T, Erne P, Pedrazzini G.

Rev Esp Cardiol (Engl Ed). 2018 Apr 10. pii: S1885-5857(18)30079-3. doi: 10.1016/j.rec.2018.03.002. [Epub ahead of print] English, Spanish.


Multiple embolization in infective endocarditis.

Boscolo Berto M, Biasco L, Demertzis S, Pedrazzini GB.

Eur Heart J. 2018 May 14;39(19):1739. doi: 10.1093/eurheartj/ehy073. No abstract available.


Tiara Valve Implantation in a Patient With Previously Implanted Mono-disk Mechanical Aortic Prosthesis.

Ferrari E, Biasco L, Faletra F, Cheung A, Moccetti M, Pedrazzini G, Demertzis S, Moccetti T.

Semin Thorac Cardiovasc Surg. 2018 Summer;30(2):160-163. doi: 10.1053/j.semtcvs.2018.02.028. Epub 2018 Mar 5.


Angiography vs transesophageal echocardiography-guided patent foramen ovale closure: A propensity score matched analysis of a two-center registry.

Scacciatella P, Meynet I, Giorgi M, Biava LM, Matranga I, Biasco L, Omedè P, Orzan F, Gaita F.

Echocardiography. 2018 Jun;35(6):834-840. doi: 10.1111/echo.13842. Epub 2018 Feb 19.


Integration Site Analysis in Gene Therapy Patients: Expectations and Reality.

Biasco L.

Hum Gene Ther. 2017 Dec;28(12):1122-1129. doi: 10.1089/hum.2017.183. Review.


Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy.

Biasco L, Rothe M, Büning H, Schambach A.

Mol Ther Methods Clin Dev. 2017 Oct 5;8:21-30. doi: 10.1016/j.omtm.2017.10.002. eCollection 2018 Mar 16. Review.


Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis.

Biasco L, Rothe M, Schott JW, Schambach A.

Hematol Oncol Clin North Am. 2017 Oct;31(5):737-752. doi: 10.1016/j.hoc.2017.06.009. Review.


Multiparametric Whole Blood Dissection: A one-shot comprehensive picture of the human hematopoietic system.

Basso-Ricci L, Scala S, Milani R, Migliavacca M, Rovelli A, Bernardo ME, Ciceri F, Aiuti A, Biasco L.

Cytometry A. 2017 Oct;91(10):952-965. doi: 10.1002/cyto.a.23148. Epub 2017 Jun 13.


Echocardiographic-Fluoroscopic Fusion Imaging in Transseptal Puncture: A New Technology for an Old Procedure.

Faletra FF, Biasco L, Pedrazzini G, Moccetti M, Pasotti E, Leo LA, Cautilli G, Moccetti T, Monaghan MJ.

J Am Soc Echocardiogr. 2017 Sep;30(9):886-895. doi: 10.1016/j.echo.2017.05.001. Epub 2017 Jun 7. Review.


Safety and Efficacy of Transcatheter Aortic Valve Replacement in the Treatment of Pure Aortic Regurgitation in Native Valves and Failing Surgical Bioprostheses: Results From an International Registry Study.

Sawaya FJ, Deutsch MA, Seiffert M, Yoon SH, Codner P, Wickramarachchi U, Latib A, Petronio AS, Rodés-Cabau J, Taramasso M, Spaziano M, Bosmans J, Biasco L, Mylotte D, Savontaus M, Gheeraert P, Chan J, Jørgensen TH, Sievert H, Mocetti M, Lefèvre T, Maisano F, Mangieri A, Hildick-Smith D, Kornowski R, Makkar R, Bleiziffer S, Søndergaard L, De Backer O.

JACC Cardiovasc Interv. 2017 May 22;10(10):1048-1056. doi: 10.1016/j.jcin.2017.03.004.


Multicenter Experience With Treatment of Residual Mitral Regurgitation After MitraClip Implantation Using Amplatzer Closure Device: Mid-Term Results.

Taramasso M, Alessandrini H, Kuwata S, Biasco L, Nietlispach F, Gaemperli O, Zuber M, Linka A, Pedrazzini G, Kreidel F, Frerker C, Kuck KH, Maisano F.

JACC Cardiovasc Interv. 2017 May 8;10(9):966-970. doi: 10.1016/j.jcin.2017.02.011. No abstract available.


Evaluation of a protocol for same-day discharge after radial lounge monitoring in a southern Swiss referral percutaneous coronary intervention centre.

Biasco L, Pedrazzini GB, Araco M, Petracca F, Del Monte D, Sürder D, Bomio F, Berto MB, Montrasio G, Del Bufalo A, Pasotti E, Moccetti T, Moccetti M.

J Cardiovasc Med (Hagerstown). 2017 Aug;18(8):590-595. doi: 10.2459/JCM.0000000000000519.


EAPCI Focus on the EAPCI Fellowship Experience. An interview with Luigi Biasco, EAPCI Fellowship awardee 2014.

Biasco L.

EuroIntervention. 2016 Apr;11(14):2 p following e1576-8. No abstract available.


Electrocardiograms of Children and Adolescents Practicing Non-competitive Sports: Normal Limits and Abnormal Findings in a Large European Cohort Evaluated by Telecardiology.

Molinari G, Brunetti ND, Biasco L, Squarcia S, Cristoforetti Y, Bennicelli R, Del Vecchio C, Viacava C, Giustetto C, Gaita F.

Sports Med. 2017 Mar;47(3):555-563. doi: 10.1007/s40279-016-0609-7.


In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A.

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016. Epub 2016 May 26.


Invasive angiography and revascularization in patients with stable angina following prior coronary artery bypass grafting: Results from the East Denmark heart registry.

Joshi FR, Biasco L, Pedersen F, Holmvang L, Helqvist S, Tilsted HH, Abildgaard U, Kelbaek H, Lassen JF, Jørgensen E, De Backer O, Engstrøm T.

Catheter Cardiovasc Interv. 2017 Feb 15;89(3):341-349. doi: 10.1002/ccd.26598. Epub 2016 May 24.


Current Approaches and Future Perspectives for In Vivo Clonal Tracking of Hematopoietic Cells.

Scala S, Leonardelli L, Biasco L.

Curr Gene Ther. 2016;16(3):184-93. Review.


First-in-Man Experience With the ClearLumen Thrombectomy System as an Adjunctive Therapy in Primary Percutaneous Coronary Interventions.

Biasco L, Götberg M, Harnek J, Lundin A, Kandzari DE, De Backer O, Olivecrona GK.

J Interv Cardiol. 2016 Apr;29(2):155-61. doi: 10.1111/joic.12285.


Acquired intracoronary ADAMTS13 deficiency and VWF retention at sites of critical coronary stenosis in patients with STEMI.

Pedrazzini G, Biasco L, Sulzer I, Anesini A, Moccetti T, Kremer Hovinga JA, Alberio L.

Blood. 2016 Jun 9;127(23):2934-6. doi: 10.1182/blood-2015-12-688010. Epub 2016 Mar 31. No abstract available.


Long-term outcome of FFR-guided PCI for stable coronary artery disease in daily clinical practice: a propensity score-matched landmark analysis.

De Backer O, Biasco L, Lønborg J, Pedersen F, Holmvang L, Kelbaek H, Arnous S, Saunamäki K, Helqvist S, Kastrup J, Jørgensen E, Engstrøm T.

EuroIntervention. 2016 Feb;11(11):e1257-66. doi: 10.4244/EIJV11I11A247.


Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

Oliveira G, Ruggiero E, Stanghellini MT, Cieri N, D'Agostino M, Fronza R, Lulay C, Dionisio F, Mastaglio S, Greco R, Peccatori J, Aiuti A, Ambrosi A, Biasco L, Bondanza A, Lambiase A, Traversari C, Vago L, von Kalle C, Schmidt M, Bordignon C, Ciceri F, Bonini C.

Sci Transl Med. 2015 Dec 9;7(317):317ra198. doi: 10.1126/scitranslmed.aac8265. Erratum in: Sci Transl Med. 2015 Dec 23;7(319):319er9. D'Agostino, Mattio [corrected to D'Agostino, Mattia].


J-wave duration and slope as potential tools to discriminate between benign and malignant early repolarization.

Cristoforetti Y, Biasco L, Giustetto C, De Backer O, Castagno D, Astegiano P, Ganzit G, Gribaudo CG, Moccetti M, Gaita F.

Heart Rhythm. 2016 Mar;13(3):806-11. doi: 10.1016/j.hrthm.2015.11.029. Epub 2015 Nov 18. Review. No abstract available.


Early repolarization: an evolving concept for the past 70 years.

Biasco L, Cristoforetti Y, De Backer O, Castagno D, Giustetto C, Orzan F, Gaita F.

J Cardiovasc Med (Hagerstown). 2016 Jan;17(1):4-10. doi: 10.2459/JCM.0000000000000276. Review.


Prehospital administration of P2Y12 inhibitors and early coronary reperfusion in primary PCI: an observational comparative study.

De Backer O, Ratcovich H, Biasco L, Pedersen F, Helqvist S, Saunamäki K, Tilsted HH, Clemmensen P, Olivecrona G, Kelbaek H, Jørgensen E, Engstrøm T, Holmvang L.

Thromb Haemost. 2015 Aug 31;114(3):623-31. doi: 10.1160/TH15-01-0026. Epub 2015 May 21.


Angiographic characteristics of intermediate stenosis of the left anterior descending artery for determination of lesion significance as identified by fractional flow reserve.

Biasco L, Pedersen F, Lønborg J, Holmvang L, Helqvist S, Saunamäki K, Kelbaek H, Clemmensen P, Olivecrona GK, Jørgensen E, Engstrøm T, De Backer O.

Am J Cardiol. 2015 Jun 1;115(11):1475-80. doi: 10.1016/j.amjcard.2015.02.047. Epub 2015 Mar 11.


Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting.

Cesani M, Plati T, Lorioli L, Benedicenti F, Redaelli D, Dionisio F, Biasco L, Montini E, Naldini L, Biffi A.

Gene Ther. 2015 Jun;22(6):496-502. doi: 10.1038/gt.2015.10. Epub 2015 Mar 12.


Safety and efficacy of using the Viabahn endoprosthesis for percutaneous treatment of vascular access complications after transfemoral aortic valve implantation.

De Backer O, Arnous S, Sandholt B, Brooks M, Biasco L, Franzen O, Lönn L, Bech B, Søndergaard L.

Am J Cardiol. 2015 Apr 15;115(8):1123-9. doi: 10.1016/j.amjcard.2015.01.547. Epub 2015 Feb 3.


In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.

Biasco L, Scala S, Basso Ricci L, Dionisio F, Baricordi C, Calabria A, Giannelli S, Cieri N, Barzaghi F, Pajno R, Al-Mousa H, Scarselli A, Cancrini C, Bordignon C, Roncarolo MG, Montini E, Bonini C, Aiuti A.

Sci Transl Med. 2015 Feb 4;7(273):273ra13. doi: 10.1126/scitranslmed.3010314.


The "Chimney approach" for transcatheter aortic valve implantation: A strategy for trans axillarian bareback approach in patients with no other access options.

Biasco L, De Backer O, Holme S, Søndergaard L, Jönsson A.

Catheter Cardiovasc Interv. 2015 Sep;86(3):E167-73. doi: 10.1002/ccd.25840. Epub 2015 Feb 3.


Percutaneous closure of atrial septal defect in adults: very long-term clinical outcome and effects on aortic and mitral valve function.

Scacciatella P, Marra S, Pullara A, Conrotto F, Marchetti M, Ferraro G, Pavani M, Biasco L, Bongiovanni D, Gaita F, Orzan F.

J Invasive Cardiol. 2015 Jan;27(1):65-9.


Recovery from anemia in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation--prevalence, predictors and clinical outcome.

De Backer O, Arnous S, Lønborg J, Brooks M, Biasco L, Jönsson A, Franzen OW, Søndergaard L.

PLoS One. 2014 Dec 1;9(12):e114038. doi: 10.1371/journal.pone.0114038. eCollection 2014.


Percutaneous implantation of a second device in patients with residual right-to-left shunt after patent foramen ovale closure.

Rovera C, Biasco L, Orzan F, Belli R, Omedè P, Gaita F.

J Interv Cardiol. 2014 Dec;27(6):548-54. doi: 10.1111/joic.12162. Epub 2014 Nov 24.


Catheter closure of atrial septal defects using the Cocoon septal occluder: preliminary results of a European multicenter study.

Thanopoulos BD, Biasco L, Dardas P, De Backer O, Avraamides P, Deleanou D, Ninios V, Mavrommatis PP, Soendergaard L.

Int J Cardiol. 2014 Dec 15;177(2):418-22. doi: 10.1016/j.ijcard.2014.09.006. Epub 2014 Oct 11.


Safety of gene therapy: new insights to a puzzling case.

Rothe M, Schambach A, Biasco L.

Curr Gene Ther. 2014;14(6):429-36. Review.


Patent foramen ovale treatment strategy: an Italian large prospective study.

Alushi B, Biasco L, Orzan F, Omedé P, Sciuto F, Moretti C, Belli R, Defilippi G, Barisone G, Cerrato P, Gaita F.

J Cardiovasc Med (Hagerstown). 2014 Oct;15(10):761-8. doi: 10.2459/JCM.0000000000000138.


Impact of transcatheter closure of patent foramen ovale in the evolution of migraine and role of residual shunt.

Biasco L, Infantino V, Orzan F, Vicentini S, Rovera C, Longo G, Chinaglia A, Belli R, Allais G, Gaita F.

J Cardiol. 2014 Nov;64(5):390-4. doi: 10.1016/j.jjcc.2014.02.023. Epub 2014 Apr 6.


Clinical, electrocardiographic, echocardiographic characteristics and long-term follow-up of elite soccer players with J-point elevation.

Biasco L, Cristoforetti Y, Castagno D, Giustetto C, Astegiano P, Ganzit G, Gribaudo CG, Gaita F.

Circ Arrhythm Electrophysiol. 2013 Dec;6(6):1178-84. doi: 10.1161/CIRCEP.113.000434. Epub 2013 Oct 4.


Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Biffi A, Montini E, Lorioli L, Cesani M, Fumagalli F, Plati T, Baldoli C, Martino S, Calabria A, Canale S, Benedicenti F, Vallanti G, Biasco L, Leo S, Kabbara N, Zanetti G, Rizzo WB, Mehta NA, Cicalese MP, Casiraghi M, Boelens JJ, Del Carro U, Dow DJ, Schmidt M, Assanelli A, Neduva V, Di Serio C, Stupka E, Gardner J, von Kalle C, Bordignon C, Ciceri F, Rovelli A, Roncarolo MG, Aiuti A, Sessa M, Naldini L.

Science. 2013 Aug 23;341(6148):1233158. doi: 10.1126/science.1233158. Epub 2013 Jul 11.


Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.


Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.

Scaramuzza S, Biasco L, Ripamonti A, Castiello MC, Loperfido M, Draghici E, Hernandez RJ, Benedicenti F, Radrizzani M, Salomoni M, Ranzani M, Bartholomae CC, Vicenzi E, Finocchi A, Bredius R, Bosticardo M, Schmidt M, von Kalle C, Montini E, Biffi A, Roncarolo MG, Naldini L, Villa A, Aiuti A.

Mol Ther. 2013 Jan;21(1):175-84. doi: 10.1038/mt.2012.23. Epub 2012 Feb 28. Erratum in: Mol Ther. 2016 Jun;24(6):1159.


Retroviral integrations in gene therapy trials.

Biasco L, Baricordi C, Aiuti A.

Mol Ther. 2012 Apr;20(4):709-16. doi: 10.1038/mt.2011.289. Epub 2012 Jan 17. Review.


Respiratory and leg muscles perceived exertion during exercise at altitude.

Aliverti A, Kayser B, Lo Mauro A, Quaranta M, Pompilio P, Dellacà RL, Ora J, Biasco L, Cavalleri L, Pomidori L, Cogo A, Pellegrino R, Miserocchi G.

Respir Physiol Neurobiol. 2011 Jul 31;177(2):162-8. doi: 10.1016/j.resp.2011.03.014. Epub 2011 Mar 22.


Visualization of multiple catheters with electroanatomical mapping reduces X-ray exposure during atrial fibrillation ablation.

Scaglione M, Biasco L, Caponi D, Anselmino M, Negro A, Di Donna P, Corleto A, Montefusco A, Gaita F.

Europace. 2011 Jul;13(7):955-62. doi: 10.1093/europace/eur062. Epub 2011 Mar 18.


Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell.

Biasco L, Ambrosi A, Pellin D, Bartholomae C, Brigida I, Roncarolo MG, Di Serio C, von Kalle C, Schmidt M, Aiuti A.

EMBO Mol Med. 2011 Feb;3(2):89-101. doi: 10.1002/emmm.201000108. Epub 2011 Jan 17.


Left atrial volume at MRI is the main determinant of outcome after pulmonary vein isolation plus linear lesion ablation for paroxysmal-persistent atrial fibrillation.

Montefusco A, Biasco L, Blandino A, Cristoforetti Y, Scaglione M, Caponi D, Di Donna P, Boffano C, Cesarani F, Coin D, Perversi J, Gaita F.

J Cardiovasc Med (Hagerstown). 2010 Aug;11(8):593-8. doi: 10.2459/JCM.0b013e32833831e4.


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