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Items: 10

1.

The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance.

Biancur DE, Kimmelman AC.

Biochim Biophys Acta. 2018 Apr 24. pii: S0304-419X(17)30213-5. doi: 10.1016/j.bbcan.2018.04.011. [Epub ahead of print] Review.

PMID:
29702208
2.

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.

Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC.

Cancer Discov. 2018 Mar;8(3):276-287. doi: 10.1158/2159-8290.CD-17-0952. Epub 2018 Jan 9.

PMID:
29317452
3.

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.

Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T.

Elife. 2017 Oct 2;6. pii: e28083. doi: 10.7554/eLife.28083.

4.

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.

Biancur DE, Paulo JA, Małachowska B, Quiles Del Rey M, Sousa CM, Wang X, Sohn ASW, Chu GC, Gygi SP, Harper JW, Fendler W, Mancias JD, Kimmelman AC.

Nat Commun. 2017 Jul 3;8:15965. doi: 10.1038/ncomms15965.

5.

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.

Nature. 2016 Dec 1;540(7631):150. doi: 10.1038/nature19851. Epub 2016 Oct 5. No abstract available.

PMID:
27706144
6.

Key clinical beam parameters for nanoparticle-mediated radiation dose amplification.

Detappe A, Kunjachan S, Drané P, Kotb S, Myronakis M, Biancur DE, Ireland T, Wagar M, Lux F, Tillement O, Berbeco R.

Sci Rep. 2016 Sep 23;6:34040. doi: 10.1038/srep34040.

7.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.

Nature. 2016 Aug 25;536(7617):479-83. doi: 10.1038/nature19084. Epub 2016 Aug 10. Erratum in: Nature. 2016 Dec 1;540(7631):150.

8.

Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy.

Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R.

J Control Release. 2016 Sep 28;238:103-113. doi: 10.1016/j.jconrel.2016.07.021. Epub 2016 Jul 14.

PMID:
27423325
9.

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW.

Elife. 2015 Oct 5;4. doi: 10.7554/eLife.10308.

10.

Nanoparticle Mediated Tumor Vascular Disruption: A Novel Strategy in Radiation Therapy.

Kunjachan S, Detappe A, Kumar R, Ireland T, Cameron L, Biancur DE, Motto-Ros V, Sancey L, Sridhar S, Makrigiorgos GM, Berbeco RI.

Nano Lett. 2015 Nov 11;15(11):7488-96. doi: 10.1021/acs.nanolett.5b03073. Epub 2015 Oct 6.

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