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Items: 1 to 50 of 182

1.

D-Ring-Modified Analogues of Luotonin A with Reduced Planarity: Design, Synthesis, and Evaluation of Their Topoisomerase Inhibition-Associated Cytotoxicity.

Almansour AI, Kumar RS, Arumugam N, Bianchini G, Menéndez JC, Mohammad F, Dupadahalli K, Altaf M.

Biomed Res Int. 2019 Nov 13;2019:2514524. doi: 10.1155/2019/2514524. eCollection 2019.

2.

Catalyst-Free Synthesis of Polysubstituted 5-Acylamino-1,3-Thiazoles via Hantzsch Cyclization of α-Chloroglycinates.

Tomassetti M, Lupidi G, Piermattei P, Rossi FV, Lillini S, Bianchini G, Aramini A, Ciufolini MA, Marcantoni E.

Molecules. 2019 Oct 25;24(21). pii: E3846. doi: 10.3390/molecules24213846.

3.

DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain.

Brandolini L, Castelli V, Aramini A, Giorgio C, Bianchini G, Russo R, De Caro C, d'Angelo M, Catanesi M, Benedetti E, Giordano A, Cimini A, Allegretti M.

Sci Rep. 2019 Aug 13;9(1):11729. doi: 10.1038/s41598-019-48231-z.

4.

Predictive and prognostic value of stromal tumour-infiltrating lymphocytes before and after neoadjuvant therapy in triple negative and HER2-positive breast cancer.

Ochi T, Bianchini G, Ando M, Nozaki F, Kobayashi D, Criscitiello C, Curigliano G, Iwamoto T, Niikura N, Takei H, Yoshida A, Takei J, Suzuki K, Yamauchi H, Hayashi N.

Eur J Cancer. 2019 Sep;118:41-48. doi: 10.1016/j.ejca.2019.05.014. Epub 2019 Jul 11.

PMID:
31302586
5.

Heavy oxygen recycled into the lithospheric mantle.

Dallai L, Bianchini G, Avanzinelli R, Natali C, Conticelli S.

Sci Rep. 2019 Jun 19;9(1):8793. doi: 10.1038/s41598-019-45031-3.

6.

Correction to: The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury.

Brandolini L, Grannonico M, Bianchini G, Colanardi A, Sebastiani P, Paladini A, Piroli A, Allegretti M, Varrassi G, Di Loreto S.

Neurotox Res. 2019 Aug;36(2):439. doi: 10.1007/s12640-019-00049-3.

7.

Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain.

Dal-Pont GC, Resende WR, Bianchini G, Gava FF, Peterle BR, Trajano KS, Varela RB, Quevedo J, Valvassori SS.

J Psychiatr Res. 2019 Jun;113:181-189. doi: 10.1016/j.jpsychires.2019.03.020. Epub 2019 Mar 26.

PMID:
30981159
8.

The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury.

Brandolini L, Grannonico M, Bianchini G, Colanardi A, Sebastiani P, Paladini A, Piroli A, Allegretti M, Varrassi G, Di Loreto S.

Neurotox Res. 2019 Jul;36(1):163-174. doi: 10.1007/s12640-019-00026-w. Epub 2019 Apr 5. Erratum in: Neurotox Res. 2019 May 6;:.

9.

Correction: Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer.

Hanker AB, Estrada MV, Bianchini G, Moore PD, Zhao J, Cheng F, Koch JP, Gianni L, Tyson DR, Sánchez V, Rexer BN, Sanders ME, Zhao Z, Stricker TP, Arteaga CL.

Cancer Res. 2019 Feb 15;79(4):873. doi: 10.1158/0008-5472.CAN-18-4085. No abstract available.

10.

Insights Into the Evolution of Picocyanobacteria and Phycoerythrin Genes (mpeBA and cpeBA).

Sánchez-Baracaldo P, Bianchini G, Di Cesare A, Callieri C, Chrismas NAM.

Front Microbiol. 2019 Jan 30;10:45. doi: 10.3389/fmicb.2019.00045. eCollection 2019.

11.

Is trastuzumab as a single agent obsolete in early breast cancer? No.

Bianchini G.

Breast. 2019 Feb;43:142-145. doi: 10.1016/j.breast.2018.09.002. Epub 2018 Dec 19.

PMID:
30578129
12.

Immunological differences between primary and metastatic breast cancer.

Szekely B, Bossuyt V, Li X, Wali VB, Patwardhan GA, Frederick C, Silber A, Park T, Harigopal M, Pelekanou V, Zhang M, Yan Q, Rimm DL, Bianchini G, Hatzis C, Pusztai L.

Ann Oncol. 2018 Nov 1;29(11):2232-2239. doi: 10.1093/annonc/mdy399.

13.

Intramuscular Venous Malformations of the Upper and Lower Limbs: Indications and Outcomes of Sclerotherapy.

Bianchini G, Camilli D, Furgiuele S.

Cardiovasc Intervent Radiol. 2018 Oct;41(10):1505-1512. doi: 10.1007/s00270-018-1997-x. Epub 2018 May 30.

PMID:
29850938
14.

Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.

De Caro C, Russo R, Avagliano C, Cristiano C, Calignano A, Aramini A, Bianchini G, Allegretti M, Brandolini L.

Br J Pharmacol. 2018 May;175(10):1691-1706. doi: 10.1111/bph.14177. Epub 2018 Apr 14.

15.

Dissecting Time- from Tumor-Related Gene Expression Variability in Bilateral Breast Cancer.

Callari M, Dugo M, Miodini P, Veneroni S, Bianchini G, Daidone MG, Cappelletti V.

Int J Mol Sci. 2018 Jan 9;19(1). pii: E196. doi: 10.3390/ijms19010196.

16.

Natural vs anthropogenic components in sediments from the Po River delta coastal lagoons (NE Italy).

Natali C, Bianchini G.

Environ Sci Pollut Res Int. 2018 Jan;25(3):2981-2991. doi: 10.1007/s11356-017-0986-y. Epub 2017 Dec 19.

PMID:
29260480
17.

Reply to Nakov et al.: Model choice requires biological insight when studying the ancestral habitat of photosynthetic eukaryotes.

Sánchez-Baracaldo P, Bianchini G, Huelsenbeck JP, Raven JA, Pisani D, Knoll AH.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10608-E10609. doi: 10.1073/pnas.1717417114. Epub 2017 Dec 5. No abstract available.

18.

Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity.

Uliassi E, Fiorani G, Krauth-Siegel RL, Bergamini C, Fato R, Bianchini G, Carlos Menéndez J, Molina MT, López-Montero E, Falchi F, Cavalli A, Gul S, Kuzikov M, Ellinger B, Witt G, Moraes CB, Freitas-Junior LH, Borsari C, Costi MP, Bolognesi ML.

Eur J Med Chem. 2017 Dec 1;141:138-148. doi: 10.1016/j.ejmech.2017.10.005. Epub 2017 Oct 3.

PMID:
29031061
19.

Tumour-infiltrating lymphocytes (TILs)-related genomic signature predicts chemotherapy response in breast cancer.

Kochi M, Iwamoto T, Niikura N, Bianchini G, Masuda S, Mizoo T, Nogami T, Shien T, Motoki T, Taira N, Tokuda Y, Doihara H, Matsuoka J, Fujiwara T.

Breast Cancer Res Treat. 2018 Jan;167(1):39-47. doi: 10.1007/s10549-017-4502-3. Epub 2017 Sep 13.

PMID:
28905250
20.

The different effects of lithium and tamoxifen on memory formation and the levels of neurotrophic factors in the brain of male and female rats.

Valvassori SS, Borges CP, Varela RB, Bavaresco DV, Bianchini G, Mariot E, Arent CO, Resende WR, Budni J, Quevedo J.

Brain Res Bull. 2017 Sep;134:228-235. doi: 10.1016/j.brainresbull.2017.08.006. Epub 2017 Aug 9.

PMID:
28802897
21.

Design, synthesis and antiproliferative activity of decarbonyl luotonin analogues.

Almansour AI, Arumugam N, Suresh Kumar R, Mahalingam SM, Sau S, Bianchini G, Menéndez JC, Altaf M, Ghabbour HA.

Eur J Med Chem. 2017 Sep 29;138:932-941. doi: 10.1016/j.ejmech.2017.07.027. Epub 2017 Jul 18.

PMID:
28753517
22.

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer.

Karn T, Jiang T, Hatzis C, Sänger N, El-Balat A, Rody A, Holtrich U, Becker S, Bianchini G, Pusztai L.

JAMA Oncol. 2017 Dec 1;3(12):1707-1711. doi: 10.1001/jamaoncol.2017.2140.

23.

Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer.

Safonov A, Jiang T, Bianchini G, Győrffy B, Karn T, Hatzis C, Pusztai L.

Cancer Res. 2017 Jun 15;77(12):3317-3324. doi: 10.1158/0008-5472.CAN-16-3478. Epub 2017 Apr 20.

24.

Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer.

Hanker AB, Estrada MV, Bianchini G, Moore PD, Zhao J, Cheng F, Koch JP, Gianni L, Tyson DR, Sánchez V, Rexer BN, Sanders ME, Zhao Z, Stricker TP, Arteaga CL.

Cancer Res. 2017 Jun 15;77(12):3280-3292. doi: 10.1158/0008-5472.CAN-16-2808. Epub 2017 Apr 10. Erratum in: Cancer Res. 2019 Feb 15;79(4):873.

25.

Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer.

Bianchini G, Kiermaier A, Bianchi GV, Im YH, Pienkowski T, Liu MC, Tseng LM, Dowsett M, Zabaglo L, Kirk S, Szado T, Eng-Wong J, Amler LC, Valagussa P, Gianni L.

Breast Cancer Res. 2017 Feb 9;19(1):16. doi: 10.1186/s13058-017-0806-9.

26.

Gemcitabine-induced thrombocytosis as a potential predictive factor in non-small cell lung cancer: analysis of 318 patients.

Canova S, Cicchiello F, Agustoni F, Bianchini G, Abbate MI, Bidoli P, Cortinovis DL.

Tumori. 2017 Mar 24;103(2):143-147. doi: 10.5301/tj.5000584. Epub 2016 Nov 28.

PMID:
28009425
27.

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease.

Bianchini G, Balko JM, Mayer IA, Sanders ME, Gianni L.

Nat Rev Clin Oncol. 2016 Nov;13(11):674-690. doi: 10.1038/nrclinonc.2016.66. Epub 2016 May 17. Review.

28.

Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients.

Ogiya R, Niikura N, Kumaki N, Bianchini G, Kitano S, Iwamoto T, Hayashi N, Yokoyama K, Oshitanai R, Terao M, Morioka T, Tsuda B, Okamura T, Saito Y, Suzuki Y, Tokuda Y.

Cancer Sci. 2016 Dec;107(12):1730-1735. doi: 10.1111/cas.13101.

29.

[Linee guida flebo-linfologiche SIF-SICVE 2016 della Società Italiana di Flebologia e della Società Italiana di Chirurgia Vascolare ed Endovascolare].

Ebner H, Stillo F, Lanza G, Mangialardi N, Agus GB, Apperti M, Bernardini E, Bernardini M, Bernardo B, Bianchini G, Bisacci R, Camparini S, Chiulli N, Corda D, Crespi A, De Fiores A, Di Mitri R, Dorigo W, Ebner JA, Emanuelli G, Ferrara F, Genovese G, Giacomelli E, Giannasio B, Gossetti B, Guerra M, Mattaliano V, Musiani A, Pieroni O, Piccioli R, Pisacreta M, Pratesi C, Ronchey S, Quarto G, Sellitti A, Spinelli GM, Strati E, Tori A, Viani M, Zolesio P.

Minerva Cardioangiol. 2016 Aug;64(4 Suppl 2):1-80. Italian.

30.

Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC.

J Med Chem. 2016 Aug 25;59(16):7697. doi: 10.1021/acs.jmedchem.6b01091. Epub 2016 Aug 3. No abstract available.

PMID:
27487560
31.

Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC.

J Med Chem. 2016 Jun 23;59(12):5661-83. doi: 10.1021/acs.jmedchem.5b01448. Epub 2016 Jun 14. Erratum in: J Med Chem. 2016 Aug 25;59(16):7697.

PMID:
27232526
32.

Natural and anthropogenic variations in the Po river waters (northern Italy): insights from a multi-isotope approach.

Marchina C, Bianchini G, Knoeller K, Natali C, Pennisi M, Colombani N.

Isotopes Environ Health Stud. 2016 Dec;52(6):649-72. doi: 10.1080/10256016.2016.1152965. Epub 2016 Mar 16.

PMID:
26982695
33.

Geochemistry of the Adige River water from the Eastern Alps to the Adriatic Sea (Italy): evidences for distinct hydrological components and water-rock interactions.

Natali C, Bianchini G, Marchina C, Knöller K.

Environ Sci Pollut Res Int. 2016 Jun;23(12):11677-94. doi: 10.1007/s11356-016-6356-3. Epub 2016 Mar 4.

PMID:
26939690
34.

New Strategies in Breast Cancer: Immunotherapy.

Pusztai L, Karn T, Safonov A, Abu-Khalaf MM, Bianchini G.

Clin Cancer Res. 2016 May 1;22(9):2105-10. doi: 10.1158/1078-0432.CCR-15-1315. Epub 2016 Feb 11.

35.

Assessing cost-utility of predictive biomarkers in oncology: a streamlined approach.

Safonov A, Wang S, Gross CP, Agarwal D, Bianchini G, Pusztai L, Hatzis C.

Breast Cancer Res Treat. 2016 Jan;155(2):223-34. doi: 10.1007/s10549-016-3677-3. Epub 2016 Jan 9.

36.

DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain.

Lopes AH, Brandolini L, Aramini A, Bianchini G, Silva RL, Zaperlon AC, Verri WA Jr, Alves-Filho JC, Cunha FQ, Teixeira MM, Allegretti M, Cunha TM.

Pharmacol Res. 2016 Jan;103:69-79. doi: 10.1016/j.phrs.2015.11.005. Epub 2015 Nov 28.

37.

Establishing the Evidence Bar for Molecular Diagnostics in Personalised Cancer Care.

Schneider D, Bianchini G, Horgan D, Michiels S, Witjes W, Hills R, Plun-Favreau J, Brand A, Lawler M; EAPM Working Group for Oncology Clinical Research.

Public Health Genomics. 2015;18(6):349-58. doi: 10.1159/000441556. Epub 2015 Nov 11.

38.

DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.

Mistretta FA, Russo A, Castiglione F, Bettiga A, Colciago G, Montorsi F, Brandolini L, Aramini A, Bianchini G, Allegretti M, Bovolenta S, Russo R, Benigni F, Hedlund P.

J Pharmacol Exp Ther. 2016 Jan;356(1):200-11. doi: 10.1124/jpet.115.228684. Epub 2015 Nov 6.

PMID:
26546575
39.

Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer.

Callari M, Cappelletti V, D'Aiuto F, Musella V, Lembo A, Petel F, Karn T, Iwamoto T, Provero P, Daidone MG, Gianni L, Bianchini G.

Clin Cancer Res. 2016 Jan 15;22(2):337-45. doi: 10.1158/1078-0432.CCR-15-0757. Epub 2015 Sep 30.

40.

Immune modulation of pathologic complete response after neoadjuvant HER2-directed therapies in the NeoSphere trial.

Bianchini G, Pusztai L, Pienkowski T, Im YH, Bianchi GV, Tseng LM, Liu MC, Lluch A, Galeota E, Magazzù D, de la Haba-Rodríguez J, Oh DY, Poirier B, Pedrini JL, Semiglazov V, Valagussa P, Gianni L.

Ann Oncol. 2015 Dec;26(12):2429-36. doi: 10.1093/annonc/mdv395. Epub 2015 Sep 19.

41.

Enhancing the Performance of Passive Teleoperation Systems via Cutaneous Feedback.

Pacchierotti C, Tirmizi A, Bianchini G, Prattichizzo D.

IEEE Trans Haptics. 2015 Oct-Dec;8(4):397-409. doi: 10.1109/TOH.2015.2457927. Epub 2015 Jul 17.

PMID:
26208364
42.

Vascular Anomalies Guidelines by the Italian Society for the study of Vascular Anomalies (SISAV).

Stillo F, Baraldini V, Dalmonte P, El Hachem M, Mattassi R, Vercellio G, Amato B, Bellini C, Bergui M, Bianchini G, Diociaiuti A, Campisi C, Gandolfo C, Gelmetti C, Moneghini L, Monti L, Magri C, Neri I, Paoloantonio G, Patrizi A, Rollo M, Santecchia L, Vaghi M, Vercellino N; Italian Society for the study of Vascular Anomalies (SISAV).

Int Angiol. 2015 Apr;34(2 Suppl 1):1-45. No abstract available.

PMID:
26159424
43.

Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma.

Cottini F, Hideshima T, Suzuki R, Tai YT, Bianchini G, Richardson PG, Anderson KC, Tonon G.

Cancer Discov. 2015 Sep;5(9):972-87. doi: 10.1158/2159-8290.CD-14-0943. Epub 2015 Jun 16.

44.

Neoadjuvant Model in Cancer Treatment: From Clinical Opportunity to Health-Care Utility.

Generali D, Fox SB, Cristofanilli M, Bianchini G, Zambelli A, Hatzis C, Barberis M, Tarricone R, Bottini A, Rossi C, Tringali M.

J Natl Cancer Inst Monogr. 2015 May;2015(51):1-3. doi: 10.1093/jncimonographs/lgv022.

PMID:
26063875
45.

The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania.

Arent CO, Valvassori SS, Steckert AV, Resende WR, Dal-Pont GC, Lopes-Borges J, Amboni RT, Bianchini G, Quevedo J.

J Psychiatr Res. 2015 Jun;65:71-9. doi: 10.1016/j.jpsychires.2015.04.011. Epub 2015 Apr 18.

PMID:
25937502
46.

Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine.

Valvassori SS, Tonin PT, Varela RB, Carvalho AF, Mariot E, Amboni RT, Bianchini G, Andersen ML, Quevedo J.

Bipolar Disord. 2015 Aug;17(5):507-17. doi: 10.1111/bdi.12299. Epub 2015 Apr 30.

PMID:
25929806
47.

Thermally based isotopic speciation of carbon in complex matrices: a tool for environmental investigation.

Natali C, Bianchini G.

Environ Sci Pollut Res Int. 2015 Aug;22(16):12162-73. doi: 10.1007/s11356-015-4503-x. Epub 2015 Apr 18.

PMID:
25893627
48.

Use of formalin-fixed paraffin-embedded samples for gene expression studies in breast cancer patients.

Musella V, Callari M, Di Buduo E, Scuro M, Dugo M, Miodini P, Bianchini G, Paolini B, Gianni L, Daidone MG, Cappelletti V.

PLoS One. 2015 Apr 6;10(4):e0123194. doi: 10.1371/journal.pone.0123194. eCollection 2015.

49.

Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats.

Varela RB, Valvassori SS, Lopes-Borges J, Mariot E, Dal-Pont GC, Amboni RT, Bianchini G, Quevedo J.

J Psychiatr Res. 2015 Feb;61:114-21. doi: 10.1016/j.jpsychires.2014.11.003. Epub 2014 Nov 21.

PMID:
25467060
50.

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief.

Moriconi A, Cunha TM, Souza GR, Lopes AH, Cunha FQ, Carneiro VL, Pinto LG, Brandolini L, Aramini A, Bizzarri C, Bianchini G, Beccari AR, Fanton M, Bruno A, Costantino G, Bertini R, Galliera E, Locati M, Ferreira SH, Teixeira MM, Allegretti M.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16937-42. doi: 10.1073/pnas.1417365111. Epub 2014 Nov 10.

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