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Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma.

Terai M, Londin E, Rochani A, Link E, Lam B, Kaushal G, Bhushan A, Orloff M, Sato T.

Cancers (Basel). 2020 Feb 10;12(2). pii: E405. doi: 10.3390/cancers12020405.


Genome mining of oxidation modules in trans-acyltransferase polyketide synthases reveals a culturable source for lobatamides.

Ueoka R, Meoded R, Gran-Scheuch A, Bhushan A, Fraaije M, Piel J.

Angew Chem Int Ed Engl. 2020 Feb 10. doi: 10.1002/anie.201916005. [Epub ahead of print]


Commentary on "Gulati P, Chavan BS, Sidana A. Comparative efficacy of baclofen and lorazepam in the treatment of alcohol withdrawal syndrome. Indian J Psychiatry. 2019;61:60-4".

Batra P, Bhushan A, Dhiman N.

Indian J Psychiatry. 2019 Nov-Dec;61(6):650-651. doi: 10.4103/psychiatry.IndianJPsychiatry_63_19. No abstract available.


Histological and Histochemical Observations on Mast Cell and Glands in Chronic Tonsillitis.

Gaur S, Sinha ON, Bhushan A, Batni G, Jain M.

Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):32-37. doi: 10.1007/s12070-015-0961-1. Epub 2015 Dec 30.


BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes.

Thompson PJ, Shah A, Apostolopolou H, Bhushan A.

Int J Mol Sci. 2019 Sep 26;20(19). pii: E4776. doi: 10.3390/ijms20194776.


Genome mining- and synthetic biology-enabled production of hypermodified peptides.

Bhushan A, Egli PJ, Peters EE, Freeman MF, Piel J.

Nat Chem. 2019 Oct;11(10):931-939. doi: 10.1038/s41557-019-0323-9. Epub 2019 Sep 9.


Automated structure prediction of trans-acyltransferase polyketide synthase products.

Helfrich EJN, Ueoka R, Dolev A, Rust M, Meoded RA, Bhushan A, Califano G, Costa R, Gugger M, Steinbeck C, Moreno P, Piel J.

Nat Chem Biol. 2019 Aug;15(8):813-821. doi: 10.1038/s41589-019-0313-7. Epub 2019 Jul 15.


mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes.

Jaafar R, Tran S, Shah AN, Sun G, Valdearcos M, Marchetti P, Masini M, Swisa A, Giacometti S, Bernal-Mizrachi E, Matveyenko A, Hebrok M, Dor Y, Rutter GA, Koliwad SK, Bhushan A.

J Clin Invest. 2019 Jul 2;130:4124-4137. doi: 10.1172/JCI127021.


The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.

Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R.

Diabetes. 2019 Sep;68(9):1806-1818. doi: 10.2337/db19-0349. Epub 2019 Jun 14.


Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation.

He J, Liu W, Ge X, Wang GC, Desai V, Wang S, Mu W, Bhardwaj V, Seifert E, Liu LZ, Bhushan A, Peiper SC, Jiang BH.

Toxicol Appl Pharmacol. 2019 Sep 1;378:114606. doi: 10.1016/j.taap.2019.114606. Epub 2019 Jun 3.


Author Correction: Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells.

Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, Bhushan A, Hebrok M.

Nat Cell Biol. 2019 Jun;21(6):792. doi: 10.1038/s41556-019-0316-3.


Activation of the mTORC1/PGC-1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium.

Summer R, Shaghaghi H, Schriner D, Roque W, Sales D, Cuevas-Mora K, Desai V, Bhushan A, Ramirez MI, Romero F.

Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1049-L1060. doi: 10.1152/ajplung.00244.2018. Epub 2019 Mar 20.


Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes.

Thompson PJ, Shah A, Ntranos V, Van Gool F, Atkinson M, Bhushan A.

Cell Metab. 2019 May 7;29(5):1045-1060.e10. doi: 10.1016/j.cmet.2019.01.021. Epub 2019 Feb 21.


Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells.

Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, Bhushan A, Hebrok M.

Nat Cell Biol. 2019 Feb;21(2):263-274. doi: 10.1038/s41556-018-0271-4. Epub 2019 Feb 1. Erratum in: Nat Cell Biol. 2019 Mar 26;:.


Combination of Biochanin A and Temozolomide Impairs Tumor Growth by Modulating Cell Metabolism in Glioblastoma Multiforme.

Desai V, Jain A, Shaghaghi H, Summer R, Lai JCK, Bhushan A.

Anticancer Res. 2019 Jan;39(1):57-66. doi: 10.21873/anticanres.13079.


Long-term intake of vegetables and fruits and subjective cognitive function in US men.

Yuan C, Fondell E, Bhushan A, Ascherio A, Okereke OI, Grodstein F, Willett WC.

Neurology. 2019 Jan 1;92(1):e63-e75. doi: 10.1212/WNL.0000000000006684. Epub 2018 Nov 21.


Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally.

Cyphert HA, Walker EM, Hang Y, Dhawan S, Haliyur R, Bonatakis L, Avrahami D, Brissova M, Kaestner KH, Bhushan A, Powers AC, Stein R.

Diabetes. 2019 Feb;68(2):337-348. doi: 10.2337/db18-0903. Epub 2018 Nov 13.


Recurrent tuberculosis among HIV-coinfected patients: a case series from KwaZulu-Natal.

Naidoo K, Dookie N, Naidoo K, Yende-Zuma N, Chimukangara B, Bhushan A, Govender D, Gengiah S, Padayatchi N.

Infect Drug Resist. 2018 Sep 5;11:1413-1421. doi: 10.2147/IDR.S150644. eCollection 2018.


Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source.

Ueoka R, Bhushan A, Probst SI, Bray WM, Lokey RS, Linington RG, Piel J.

Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14519-14523. doi: 10.1002/anie.201805673. Epub 2018 Aug 23.


D-cycloserine nasal formulation development for anxiety disorders by using polymeric gels.

Shin Y, Kokate R, Desai V, Bhushan A, Kaushal G.

Drug Discov Ther. 2018;12(3):142-153. doi: 10.5582/ddt.2018.01017.


Plasma & urinary catecholamines & urinary vanillylmandelic acid levels in patients with generalized vitiligo.

Basnet B, Bhushan A, Khan R, Kumar G, Sharma VK, Sharma A, Gupta S.

Indian J Med Res. 2018 Apr;147(4):384-390. doi: 10.4103/ijmr.IJMR_657_16.


A pilot study exploring the impact of cardiac medications on ciliary beat frequency: possible implications for clinical management.

Loomba RS, Bhushan A, Afolayan AJ.

J Basic Clin Physiol Pharmacol. 2018 Sep 25;29(5):565-571. doi: 10.1515/jbcpp-2017-0130. No abstract available.


Identifying causal variants at the interferon lambda locus in case-control studies: Utilizing non-synonymous variant rs117648444 to probe the role of IFN-λ4.

Bhushan A, Chinnaswamy S.

Gene. 2018 Jul 20;664:168-180. doi: 10.1016/j.gene.2018.04.076. Epub 2018 Apr 27. Review.


Establishment and characterization of a primary murine adipose tissue-chip.

Tanataweethum N, Zelaya A, Yang F, Cohen RN, Brey EM, Bhushan A.

Biotechnol Bioeng. 2018 Aug;115(8):1979-1987. doi: 10.1002/bit.26711. Epub 2018 May 2.


Natural Bioactive Compounds: Alternative Approach to the Treatment of Glioblastoma Multiforme.

Desai V, Bhushan A.

Biomed Res Int. 2017;2017:9363040. doi: 10.1155/2017/9363040. Epub 2017 Nov 20. Review.


Relationship between α-melanocyte stimulating hormone levels and therapeutic outcome of melanocyte transplantation and phototherapy in non-segmental patients with vitiligo: A prospective study.

Khan R, Sharma A, Bhushan A, Basnet B, Sharma VK, Gupta S.

Australas J Dermatol. 2018 Nov;59(4):e315-e318. doi: 10.1111/ajd.12769. Epub 2018 Jan 10. No abstract available.


Real-time measurement of cholesterol secreted by human hepatocytes using a novel microfluidic assay.

Karnik S, Lee C, Cancino A, Bhushan A.

Technology (Singap World Sci). 2018;6(3-4):135-141. doi: 10.1142/S2339547818500097. Epub 2018 Dec 4.


Adherence to Mediterranean diet and subjective cognitive function in men.

Bhushan A, Fondell E, Ascherio A, Yuan C, Grodstein F, Willett W.

Eur J Epidemiol. 2018 Feb;33(2):223-234. doi: 10.1007/s10654-017-0330-3. Epub 2017 Nov 17.


A microfluidic in-line ELISA for measuring secreted protein under perfusion.

Luan Q, Cahoon S, Wu A, Bale SS, Yarmush M, Bhushan A.

Biomed Microdevices. 2017 Nov 11;19(4):101. doi: 10.1007/s10544-017-0244-6.


Identification and Validation of Fibroblast Growth Factor 12 Gene as a Novel Potential Biomarker in Esophageal Cancer Using Cancer Genomic Datasets.

Bhushan A, Singh A, Kapur S, Borthakar BB, Sharma J, Rai AK, Kataki AC, Saxena S.

OMICS. 2017 Oct;21(10):616-631. doi: 10.1089/omi.2017.0116.


Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.

Nakamura K, Shirakura M, Fujisaki S, Kishida N, Burke DF, Smith DJ, Kuwahara T, Takashita E, Takayama I, Nakauchi M, Chadha M, Potdar V, Bhushan A, Upadhyay BP, Shakya G, Odagiri T, Kageyama T, Watanabe S.

Influenza Other Respir Viruses. 2017 Sep;11(5):399-403. doi: 10.1111/irv.12469. Epub 2017 Aug 9.


Cyclin D2 is sufficient to drive β cell self-renewal and regeneration.

Tschen SI, Zeng C, Field L, Dhawan S, Bhushan A, Georgia S.

Cell Cycle. 2017;16(22):2183-2191. doi: 10.1080/15384101.2017.1319999. Epub 2017 Nov 3.


Influenza A(H1N1)pdm09 outbreak detected in inter-seasonal months during the surveillance of influenza-like illness in Pune, India, 2012-2015.

Gurav YK, Chadha MS, Tandale BV, Potdar VA, Pawar SD, Shil P, Deoshatwar AR, Aarthy R, Bhushan A.

Epidemiol Infect. 2017 Jul;145(9):1898-1909. doi: 10.1017/S0950268817000553. Epub 2017 Apr 3.


Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium.

Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J.

Nat Chem. 2017 Apr;9(4):387-395. doi: 10.1038/nchem.2666. Epub 2016 Nov 28.


Observations on Tympanic Membrane Perforations (Safe Type) and Hearing Loss.

Gaur S, Sinha ON, Bhushan A, Batni G.

Indian J Otolaryngol Head Neck Surg. 2017 Mar;69(1):29-34. doi: 10.1007/s12070-016-1021-1. Epub 2016 Oct 1.


Entotheonella Bacteria as Source of Sponge-Derived Natural Products: Opportunities for Biotechnological Production.

Bhushan A, Peters EE, Piel J.

Prog Mol Subcell Biol. 2017;55:291-314. doi: 10.1007/978-3-319-51284-6_9. Review.


β Cells led astray by transcription factors and the company they keep.

Thompson P, Bhushan A.

J Clin Invest. 2017 Jan 3;127(1):94-97. doi: 10.1172/JCI91304. Epub 2016 Dec 12.


Eperisone hydrochloride-induced maculopapular rash.

Balaraddiyavar N, Bhushan A, Kotinatot BC, Huggi G.

Indian J Pharmacol. 2016 Sep-Oct;48(5):604-605.


The Use of Azoles Containing Natural Products in Cancer Prevention and Treatment: An Overview.

Jabir NR, Firoz CK, Bhushan A, Tabrez S, Kamal MA.

Anticancer Agents Med Chem. 2018;18(1):6-14. doi: 10.2174/1871520616666160520112839. Review.


Evaluation of peri-implant soft tissue and bone levels around early loaded implant in restoring single missing tooth: A clinico-radiographic study.

Bhardwaj I, Bhushan A, Baiju CS, Bali S, Joshi V.

J Indian Soc Periodontol. 2016 Jan-Feb;20(1):36-41. doi: 10.4103/0972-124X.168486.


The Right to Health of Older People.

Baer B, Bhushan A, Taleb HA, Vasquez J, Thomas R.

Gerontologist. 2016 Apr;56 Suppl 2:S206-17. doi: 10.1093/geront/gnw039. Review.


New technologies in drug metabolism and toxicity screening: organ-to-organ interaction.

Bhushan A, Martucci NJ, Usta OB, Yarmush ML.

Expert Opin Drug Metab Toxicol. 2016 May;12(5):475-7. doi: 10.1517/17425255.2016.1162292. Epub 2016 Mar 21. No abstract available.


Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication.

Dhawan S, Dirice E, Kulkarni RN, Bhushan A.

Diabetes. 2016 May;65(5):1208-18. doi: 10.2337/db15-1331. Epub 2016 Mar 2.


Roles for Transcription Factors Sp1, NF-κB, IRF3, and IRF7 in Expression of the Human IFNL4 Gene.

Chinnaswamy S, Bhushan A, Behera AK, Ghosh S, Rampurkar V, Chandra V, Pandit B, Kundu TK.

Viral Immunol. 2016 Jan-Feb;29(1):49-63. doi: 10.1089/vim.2015.0076. Epub 2015 Dec 18.


Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization.

McCarty WJ, Prodanov L, Bale SS, Bhushan A, Jindal R, Yarmush ML, Usta OB.

J Vis Exp. 2015 Sep 29;(103). doi: 10.3791/53078.


Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.

Usta OB, McCarty WJ, Bale S, Hegde M, Jindal R, Bhushan A, Golberg I, Yarmush ML.

Technology (Singap World Sci). 2015 Mar;3(1):1-26.


Long-term maintenance of a microfluidic 3D human liver sinusoid.

Prodanov L, Jindal R, Bale SS, Hegde M, McCarty WJ, Golberg I, Bhushan A, Yarmush ML, Usta OB.

Biotechnol Bioeng. 2016 Jan;113(1):241-6. doi: 10.1002/bit.25700. Epub 2015 Aug 26.


DNA methylation directs functional maturation of pancreatic β cells.

Dhawan S, Tschen SI, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A.

J Clin Invest. 2015 Jul 1;125(7):2851-60. doi: 10.1172/JCI79956. Epub 2015 Jun 22.

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