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Items: 5


Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.

Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A.

Cancer Cell. 2017 Jan 9;31(1):142-156. doi: 10.1016/j.ccell.2016.11.011. Epub 2016 Dec 22.


Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.

Bhola PD, Mar BG, Lindsley RC, Ryan JA, Hogdal LJ, Vo TT, DeAngelo DJ, Galinsky I, Ebert BL, Letai A.

J Clin Invest. 2016 Oct 3;126(10):3827-3836. doi: 10.1172/JCI82908. Epub 2016 Sep 6.


Mitochondria-Judges and Executioners of Cell Death Sentences.

Bhola PD, Letai A.

Mol Cell. 2016 Mar 3;61(5):695-704. doi: 10.1016/j.molcel.2016.02.019. Review.


Determinism and divergence of apoptosis susceptibility in mammalian cells.

Bhola PD, Simon SM.

J Cell Sci. 2009 Dec 1;122(Pt 23):4296-302. doi: 10.1242/jcs.055590. Epub 2009 Nov 3.


Spatial and temporal dynamics of mitochondrial membrane permeability waves during apoptosis.

Bhola PD, Mattheyses AL, Simon SM.

Biophys J. 2009 Oct 21;97(8):2222-31. doi: 10.1016/j.bpj.2009.07.056.

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