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Items: 16

1.

CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors.

Reinshagen C, Bhere D, Choi SH, Hutten S, Nesterenko I, Wakimoto H, Le Roux E, Rizvi A, Du W, Minicucci C, Shah K.

Sci Transl Med. 2018 Jul 11;10(449). pii: eaao3240. doi: 10.1126/scitranslmed.aao3240.

PMID:
29997250
2.

Stem Cells Engineered During Different Stages of Reprogramming Reveal Varying Therapeutic Efficacies.

Bhere D, Khajuria RK, Hendriks WT, Bandyopadhyay A, Bagci-Onder T, Shah K.

Stem Cells. 2018 Jun;36(6):932-942. doi: 10.1002/stem.2805. Epub 2018 Apr 1.

PMID:
29451340
3.

microRNA-7 upregulates death receptor 5 and primes resistant brain tumors to caspase-mediated apoptosis.

Bhere D, Tamura K, Wakimoto H, Choi SH, Purow B, Debatisse J, Shah K.

Neuro Oncol. 2018 Jan 22;20(2):215-224. doi: 10.1093/neuonc/nox138.

PMID:
29016934
4.

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM.

Cancer Discov. 2017 Nov;7(11):1336-1353. doi: 10.1158/2159-8290.CD-17-0267. Epub 2017 Oct 3.

PMID:
28974511
5.

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.

Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM.

Cell Rep. 2017 Jun 13;19(11):2304-2318. doi: 10.1016/j.celrep.2017.05.061.

6.

Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors.

Zhu Y, Bassoff N, Reinshagen C, Bhere D, Nowicki MO, Lawler SE, Roux J, Shah K.

Sci Rep. 2017 Jun 1;7(1):2602. doi: 10.1038/s41598-017-02483-9.

7.

Selective Cytotoxicity and Pro-apoptotic Activity of Stem Bark of Wrightia tinctoria (Roxb.) R. Br. in Cancerous Cells.

Chaudhary S, Devkar RA, Bhere D, Setty MM, Pai KS.

Pharmacogn Mag. 2015 Oct;11(Suppl 3):S481-7. doi: 10.4103/0973-1296.168976.

8.

Stem Cell-Based Therapies for Cancer.

Bhere D, Shah K.

Adv Cancer Res. 2015;127:159-89. doi: 10.1016/bs.acr.2015.04.012. Epub 2015 May 19. Review.

PMID:
26093900
9.

Antiangiogenic variant of TSP-1 targets tumor cells in glioblastomas.

Choi SH, Tamura K, Khajuria RK, Bhere D, Nesterenko I, Lawler J, Shah K.

Mol Ther. 2015 Feb;23(2):235-43. doi: 10.1038/mt.2014.214. Epub 2014 Oct 31.

10.

Brain tumor cells in circulation are enriched for mesenchymal gene expression.

Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, Batchelor TT, Louis DN, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2014 Nov;4(11):1299-309. doi: 10.1158/2159-8290.CD-14-0471. Epub 2014 Aug 19.

11.

AEG-1 regulates retinoid X receptor and inhibits retinoid signaling.

Srivastava J, Robertson CL, Rajasekaran D, Gredler R, Siddiq A, Emdad L, Mukhopadhyay ND, Ghosh S, Hylemon PB, Gil G, Shah K, Bhere D, Subler MA, Windle JJ, Fisher PB, Sarkar D.

Cancer Res. 2014 Aug 15;74(16):4364-77. doi: 10.1158/0008-5472.CAN-14-0421.

12.

Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors.

Martinez-Quintanilla J, Bhere D, Heidari P, He D, Mahmood U, Shah K.

Stem Cells. 2013 Aug;31(8):1706-14. doi: 10.1002/stem.1355.

13.

Real-time multi-modality imaging of glioblastoma tumor resection and recurrence.

Hingtgen S, Figueiredo JL, Farrar C, Duebgen M, Martinez-Quintanilla J, Bhere D, Shah K.

J Neurooncol. 2013 Jan;111(2):153-61. doi: 10.1007/s11060-012-1008-z. Epub 2012 Dec 16.

14.

Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects.

van de Water JA, Bagci-Onder T, Agarwal AS, Wakimoto H, Roovers RC, Zhu Y, Kasmieh R, Bhere D, Van Bergen en Henegouwen PM, Shah K.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16642-7. doi: 10.1073/pnas.1202832109. Epub 2012 Sep 25.

15.

Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors.

Tamura K, Wakimoto H, Agarwal AS, Rabkin SD, Bhere D, Martuza RL, Kuroda T, Kasmieh R, Shah K.

Mol Ther. 2013 Jan;21(1):68-77. doi: 10.1038/mt.2012.175. Epub 2012 Aug 28.

16.

Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.

Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, Stafflinger J, Subler MA, Windle JJ, Fisher PB, Sarkar D.

Hepatology. 2012 Nov;56(5):1782-91. doi: 10.1002/hep.25868.

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