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Items: 19

1.

MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia.

Evensen NA, Madhusoodhan PP, Meyer J, Saliba J, Chowdhury A, Araten DJ, Nersting J, Bhatla T, Vincent TL, Teachey D, Hunger SP, Yang J, Schmiegelow K, Carroll WL.

Haematologica. 2018 May;103(5):830-839. doi: 10.3324/haematol.2017.176362. Epub 2018 Feb 15.

2.

Primary Ewing Sarcoma of the Mastoid: A Novel Case Mimicking Acute Mastoiditis.

Egan G, Pierro J, Madhusoodhan PP, Ilyas G, Cohen B, Bhatla T.

J Pediatr Hematol Oncol. 2018 Mar;40(2):148-151. doi: 10.1097/MPH.0000000000001014.

PMID:
29176463
3.

New targeted therapies for relapsed pediatric acute lymphoblastic leukemia.

Pierro J, Hogan LE, Bhatla T, Carroll WL.

Expert Rev Anticancer Ther. 2017 Aug;17(8):725-736. doi: 10.1080/14737140.2017.1347507. Epub 2017 Jul 5. Review.

4.

Splice site mutation in factor X gene manifesting as severe intracranial haemorrhage in neonatal period with a challenging treatment course.

Madhusoodhan PP, Lu BY, Chen J, Jones CL, Meyer JA, Roman EA, Nardi M, Carroll WL, Bhatla T.

Haemophilia. 2017 Mar;23(2):e138-e140. doi: 10.1111/hae.13138. Epub 2016 Dec 19. No abstract available.

PMID:
27995737
5.

Progress and Prospects in Pediatric Leukemia.

Madhusoodhan PP, Carroll WL, Bhatla T.

Curr Probl Pediatr Adolesc Health Care. 2016 Jul;46(7):229-241. doi: 10.1016/j.cppeds.2016.04.003. Epub 2016 Jun 6. Review.

PMID:
27283082
6.

Decitabine enhances chemosensitivity of early T-cell precursor-acute lymphoblastic leukemia cell lines and patient-derived samples.

Lu BY, Thanawala SU, Zochowski KC, Burke MJ, Carroll WL, Bhatla T.

Leuk Lymphoma. 2016 Aug;57(8):1938-41. doi: 10.3109/10428194.2015.1110747. Epub 2016 Jan 4. No abstract available.

PMID:
26726842
7.

Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient.

Bhatla T, Dandekar S, Lu BY, Wang J, Han E, Bitterman D, Jones CL, Evensen NA, Magid M, Meyer JA, Carroll WL.

J Pediatr Hematol Oncol. 2016 Jan;38(1):e21-5. doi: 10.1097/MPH.0000000000000463.

8.

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.

Jones CL, Gearheart CM, Fosmire S, Delgado-Martin C, Evensen NA, Bride K, Waanders AJ, Pais F, Wang J, Bhatla T, Bitterman DS, de Rijk SR, Bourgeois W, Dandekar S, Park E, Burleson TM, Madhusoodhan PP, Teachey DT, Raetz EA, Hermiston ML, Müschen M, Loh ML, Hunger SP, Zhang J, Garabedian MJ, Porter CC, Carroll WL.

Blood. 2015 Nov 5;126(19):2202-12. doi: 10.1182/blood-2015-04-639138. Epub 2015 Aug 31.

9.

Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.

Dandekar S, Romanos-Sirakis E, Pais F, Bhatla T, Jones C, Bourgeois W, Hunger SP, Raetz EA, Hermiston ML, Dasgupta R, Morrison DJ, Carroll WL.

Br J Haematol. 2014 Oct;167(1):87-99. doi: 10.1111/bjh.13011. Epub 2014 Jul 4.

10.

Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.

Vitanza NA, Zaky W, Blum R, Meyer JA, Wang J, Bhatla T, Morrison DJ, Raetz EA, Carroll WL.

Pediatr Blood Cancer. 2014 Oct;61(10):1779-85. doi: 10.1002/pbc.25119. Epub 2014 Jun 29.

11.

The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.

Bhatla T, Jones CL, Meyer JA, Vitanza NA, Raetz EA, Carroll WL.

J Pediatr Hematol Oncol. 2014 Aug;36(6):413-8. doi: 10.1097/MPH.0000000000000179. Review.

12.

Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.

Jones CL, Bhatla T, Blum R, Wang J, Paugh SW, Wen X, Bourgeois W, Bitterman DS, Raetz EA, Morrison DJ, Teachey DT, Evans WE, Garabedian MJ, Carroll WL.

J Biol Chem. 2014 Jul 25;289(30):20502-15.

13.

Epigenetic modifications in pediatric acute lymphoblastic leukemia.

Burke MJ, Bhatla T.

Front Pediatr. 2014 May 14;2:42. doi: 10.3389/fped.2014.00042. eCollection 2014. Review.

14.

Bilateral parotid gland enlargement and palpable nephromegaly in infant acute lymphoblastic leukemia: case report and review of the literature.

Saha A, Dandekar S, Milla S, Roman E, Bhatla T.

J Pediatr Hematol Oncol. 2014 Apr;36(3):246-8. doi: 10.1097/MPH.0000000000000076. Review.

PMID:
24309613
15.

Screening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?

Meyer JA, Carroll WL, Bhatla T.

Expert Rev Hematol. 2013 Jun;6(3):223-4. doi: 10.1586/ehm.13.28. No abstract available.

16.

Where do we stand in the treatment of relapsed acute lymphoblastic leukemia?

Raetz EA, Bhatla T.

Hematology Am Soc Hematol Educ Program. 2012;2012:129-36. doi: 10.1182/asheducation-2012.1.129. Review.

PMID:
23233571
17.

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.

Bhatla T, Wang J, Morrison DJ, Raetz EA, Burke MJ, Brown P, Carroll WL.

Blood. 2012 May 31;119(22):5201-10. doi: 10.1182/blood-2012-01-401687. Epub 2012 Apr 11.

18.

Well-differentiated pancreatic neuroendocrine carcinoma in tuberous sclerosis--case report and review of the literature.

Arva NC, Pappas JG, Bhatla T, Raetz EA, Macari M, Ginsburg HB, Hajdu CH.

Am J Surg Pathol. 2012 Jan;36(1):149-53. doi: 10.1097/PAS.0b013e31823d0560. Review.

PMID:
22173120
19.

Endogenous knockdown of survivin improves chemotherapeutic response in ALL models.

Morrison DJ, Hogan LE, Condos G, Bhatla T, Germino N, Moskowitz NP, Lee L, Bhojwani D, Horton TM, Belitskaya-Levy I, Greenberger LM, Horak ID, Grupp SA, Teachey DT, Raetz EA, Carroll WL.

Leukemia. 2012 Feb;26(2):271-9. doi: 10.1038/leu.2011.199. Epub 2011 Aug 16.

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