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Items: 27

1.

Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma.

Lassman AB, Roberts-Rapp L, Sokolova I, Song M, Pestova E, Kular R, Mullen C, Zha Z, Lu X, Gomez E, Bhathena A, Maag D, Kumthekar P, Gan HK, Scott AM, Guseva M, Holen KD, Ansell PJ, van den Bent MJ.

Clin Cancer Res. 2019 Jun 1;25(11):3259-3265. doi: 10.1158/1078-0432.CCR-18-3034. Epub 2019 Feb 22.

PMID:
30796037
2.

Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.

Wang R, He Y, Robinson V, Yang Z, Hessler P, Lasko LM, Lu X, Bhathena A, Lai A, Uziel T, Lam LT.

Mol Cancer Ther. 2018 Dec;17(12):2543-2550. doi: 10.1158/1535-7163.MCT-18-0511. Epub 2018 Sep 28.

PMID:
30266801
3.

Genetic Biomarkers Of Sensitivity and Resistance to Venetoclax Monotherapy in Patients With Relapsed Acute Myeloid Leukemia.

Chyla B, Daver N, Doyle K, McKeegan E, Huang X, Ruvolo V, Wang Z, Chen K, Souers A, Leverson J, Potluri J, Boghaert E, Bhathena A, Konopleva M, Popovic R.

Am J Hematol. 2018 May 17. doi: 10.1002/ajh.25146. [Epub ahead of print] No abstract available.

4.

Vulnerability of Small-Cell Lung Cancer to Apoptosis Induced by the Combination of BET Bromodomain Proteins and BCL2 Inhibitors.

Lam LT, Lin X, Faivre EJ, Yang Z, Huang X, Wilcox DM, Bellin RJ, Jin S, Tahir SK, Mitten M, Magoc T, Bhathena A, Kati WM, Albert DH, Shen Y, Uziel T.

Mol Cancer Ther. 2017 Aug;16(8):1511-1520. doi: 10.1158/1535-7163.MCT-16-0459. Epub 2017 May 3.

5.

Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.

Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya KS, Oleksijew A, Boghaert E, Song M, Sokolova I, Pestova E, Anderson M, Pappano WN, Ansell P, Bhathena A, Naumovski L, Corvaia N, Reilly EB.

BMC Cancer. 2016 Feb 16;16:105. doi: 10.1186/s12885-016-2138-z.

6.

Plasma biomarker signature associated with improved survival in advanced non-small cell lung cancer patients on linifanib.

McKeegan EM, Ansell PJ, Davis G, Chan S, Chandran RK, Gawel SH, Dowell BL, Bhathena A, Chakravartty A, McKee MD, Ricker JL, Carlson DM, Ramalingam SS, Devanarayan V.

Lung Cancer. 2015 Nov;90(2):296-301. doi: 10.1016/j.lungcan.2015.09.011. Epub 2015 Sep 15.

PMID:
26424209
7.

Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines.

Lam LT, Zhang H, Xue J, Leverson JD, Bhathena A.

Cancer Cell Int. 2015 Feb 4;15(1):5. doi: 10.1186/s12935-014-0151-3. eCollection 2015.

8.

Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy.

Chen K, Yang D, Li X, Sun B, Song F, Cao W, Brat DJ, Gao Z, Li H, Liang H, Zhao Y, Zheng H, Li M, Buckner J, Patterson SD, Ye X, Reinhard C, Bhathena A, Joshi D, Mischel PS, Croce CM, Wang YM, Raghavakaimal S, Li H, Lu X, Pan Y, Chang H, Ba S, Luo L, Cavenee WK, Zhang W, Hao X.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1107-12. doi: 10.1073/pnas.1422640112. Epub 2015 Jan 12.

9.

Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.

Innocenti F, Ramírez J, Obel J, Xiong J, Mirkov S, Chiu YL, Katz DA, Carr RA, Zhang W, Das S, Adjei A, Moyer AM, Chen PX, Krivoshik A, Medina D, Gordon GB, Ratain MJ, Sahelijo L, Weinshilboum RM, Fleming GF, Bhathena A.

Pharmacogenet Genomics. 2013 Jul;23(7):374-81. doi: 10.1097/FPC.0b013e3283623e81.

10.

Association of dopamine-related genetic loci to dopamine D3 receptor antagonist ABT-925 clinical response.

Bhathena A, Wang Y, Kraft JB, Idler KB, Abel SJ, Holley-Shanks RR, Robieson WZ, Spear B, Redden L, Katz DA.

Transl Psychiatry. 2013 Apr 9;3:e245. doi: 10.1038/tp.2013.22.

11.

Effect of human cerebrospinal fluid sampling frequency on amyloid-β levels.

Li J, Llano DA, Ellis T, LeBlond D, Bhathena A, Jhee SS, Ereshefsky L, Lenz R, Waring JF.

Alzheimers Dement. 2012 Jul;8(4):295-303. doi: 10.1016/j.jalz.2011.05.900. Epub 2011 Nov 2.

PMID:
22047633
12.

Prospective-retrospective biomarker analysis for regulatory consideration: white paper from the industry pharmacogenomics working group.

Patterson SD, Cohen N, Karnoub M, Truter SL, Emison E, Khambata-Ford S, Spear B, Ibia E, Sproule R, Barnes D, Bhathena A, Bristow MR, Russell C, Wang D, Warner A, Westelinck A, Brian W, Snapir A, Franc MA, Wong P, Shaw PM.

Pharmacogenomics. 2011 Jul;12(7):939-51. doi: 10.2217/pgs.11.52.

PMID:
21787188
13.

Challenges in obtaining adequate genetic sample sets in clinical trials: the perspective of the industry pharmacogenomics working group.

Warner AW, Bhathena A, Gilardi S, Mohr D, Leong D, Bienfait KL, Sarang J, Duprey S, Franc MA, Nelsen A, Snapir A.

Clin Pharmacol Ther. 2011 Apr;89(4):529-36. doi: 10.1038/clpt.2010.305. Epub 2011 Feb 23.

PMID:
21346757
14.

Enabling pharmacogenomic clinical trials through sampling.

Warner A, Nelsen A, Bhathena A, Fitzgerald K, Gilardi S, Kelso E, Knoppers B, McLeod HL, Nelson R, Uyama Y, Weisman J, Rudman A.

Pharmacogenomics. 2010 Dec;11(12):1649-54. doi: 10.2217/pgs.10.139.

PMID:
21142907
15.

Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925.

Graff-Guerrero A, Redden L, Abi-Saab W, Katz DA, Houle S, Barsoum P, Bhathena A, Palaparthy R, Saltarelli MD, Kapur S.

Int J Neuropsychopharmacol. 2010 Apr;13(3):273-87. doi: 10.1017/S1461145709990642. Epub 2009 Sep 15.

PMID:
19751545
16.

Overview of pharmacogenetics.

Katz DA, Bhathena A.

Curr Protoc Hum Genet. 2009 Jan;Chapter 9:Unit 9.19. doi: 10.1002/0471142905.hg0919s60. Review.

PMID:
19170034
17.

Pharmacogenetics: improving drug and dose selection.

Bhathena A, Spear BB.

Curr Opin Pharmacol. 2008 Oct;8(5):639-46. doi: 10.1016/j.coph.2008.07.013. Epub 2008 Sep 26. Review.

PMID:
18762278
18.

Defining drug disposition determinants: a pharmacogenetic-pharmacokinetic strategy.

Katz DA, Murray B, Bhathena A, Sahelijo L.

Nat Rev Drug Discov. 2008 Apr;7(4):293-305. doi: 10.1038/nrd2486.

PMID:
18382463
19.

Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression.

Neff CD, Abkevich V, Packer JC, Chen Y, Potter J, Riley R, Davenport C, DeGrado Warren J, Jammulapati S, Bhathena A, Choi WS, Kroeger PE, Metzger RE, Gutin A, Skolnick MH, Shattuck D, Katz DA.

Mol Psychiatry. 2009 Jun;14(6):621-30. doi: 10.1038/mp.2008.8. Epub 2008 Feb 12.

PMID:
18268499
20.

Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population.

Bhathena A, Mueller T, Grimm DR, Idler K, Tsurutani A, Spear BB, Katz DA.

Drug Metab Dispos. 2007 Aug;35(8):1251-3. Epub 2007 May 9.

PMID:
17494644
21.

Characterization of the ALP1 gene locus of Trichophyton tonsurans.

Bhathena A, Gaedigk R, Abdel-Rahman SM.

Mycopathologia. 2005 Nov;160(4):265-72.

PMID:
16244893
22.

Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.

Gaedigk A, Bhathena A, Ndjountché L, Pearce RE, Abdel-Rahman SM, Alander SW, Bradford LD, Rogan PK, Leeder JS.

Pharmacogenomics J. 2005;5(3):173-82. Erratum in: Pharmacogenomics J. 2005;5(4):276. Rogan, PK [added].

23.

Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals.

Riddick DS, Lee C, Bhathena A, Timsit YE, Cheng PY, Morgan ET, Prough RA, Ripp SL, Miller KK, Jahan A, Chiang JY.

Drug Metab Dispos. 2004 Apr;32(4):367-75. Review.

PMID:
15039287
24.
25.

Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats.

Timsit YE, Chia FS, Bhathena A, Riddick DS.

Toxicol Appl Pharmacol. 2002 Dec 1;185(2):136-45.

PMID:
12490138
26.

Suppression of cytochrome P450 2C11 by aromatic hydrocarbons: mechanistic insights from studies of the 5'-flanking region of the CYP2C11 gene.

Bhathena A, Lee C, Riddick DS.

Drug Metab Dispos. 2002 Dec;30(12):1385-92. Erratum in: Drug Metab Dispos. 2005 Dec;33(12):1927.

PMID:
12433808
27.

Glutathione S-transferases in wild-type and doxorubicin-resistant MCF-7 human breast cancer cell lines.

Wang K, Ramji S, Bhathena A, Lee C, Riddick DS.

Xenobiotica. 1999 Feb;29(2):155-70.

PMID:
10199592

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