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Items: 1 to 50 of 106

1.

Hyperglycemia Associated Metabolic and Molecular Alterations in Cancer Risk, Progression, Treatment, and Mortality.

Ramteke P, Deb A, Shepal V, Bhat MK.

Cancers (Basel). 2019 Sep 19;11(9). pii: E1402. doi: 10.3390/cancers11091402. Review.

2.

Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9).

Athavale D, Chouhan S, Pandey V, Mayengbam SS, Singh S, Bhat MK.

Cancer Metab. 2018 Oct 25;6:16. doi: 10.1186/s40170-018-0187-2. eCollection 2018.

3.

SMAR1 inhibits Wnt/β-catenin signaling and prevents colorectal cancer progression.

Taye N, Alam A, Ghorai S, Chatterji DG, Parulekar A, Mogare D, Singh S, Sengupta P, Chatterjee S, Bhat MK, Santra MK, Salunkhe PB, Finston SK, Chattopadhyay S.

Oncotarget. 2018 Apr 20;9(30):21322-21336. doi: 10.18632/oncotarget.25093. eCollection 2018 Apr 20.

4.

In silico characterization of functional single nucleotide polymorphisms of folate pathway genes.

Vohra M, Sharma AR, Paul B, Bhat MK, Satyamoorthy K, Rai PS.

Ann Hum Genet. 2018 Jul;82(4):186-199. doi: 10.1111/ahg.12231. Epub 2018 Mar 25.

PMID:
29574679
5.

Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state.

Malvi P, Chaube B, Singh SV, Mohammad N, Vijayakumar MV, Singh S, Chouhan S, Bhat MK.

Cancer Metab. 2018 Mar 20;6:2. doi: 10.1186/s40170-018-0176-5. eCollection 2018.

6.

1-CMDb: A Curated Database of Genomic Variations of the One-Carbon Metabolism Pathway.

Bhat MK, Gadekar VP, Jain A, Paul B, Rai PS, Satyamoorthy K.

Public Health Genomics. 2017;20(2):136-141. doi: 10.1159/000475805. Epub 2017 May 17.

PMID:
28511181
7.

Resistin causes G1 arrest in colon cancer cells through upregulation of SOCS3.

Singh S, Chouhan S, Mohammad N, Bhat MK.

FEBS Lett. 2017 May;591(10):1371-1382. doi: 10.1002/1873-3468.12655. Epub 2017 May 6.

8.

Constitutively activated ERK sensitizes cancer cells to doxorubicin: Involvement of p53-EGFR-ERK pathway.

Kumari R, Chouhan S, Singh S, Chhipa RR, Ajay AK, Bhat MK.

J Biosci. 2017 Mar;42(1):31-41.

9.

Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance.

Malvi P, Chaube B, Singh SV, Mohammad N, Pandey V, Vijayakumar MV, Radhakrishnan RM, Vanuopadath M, Nair SS, Nair BG, Bhat MK.

Cancer Metab. 2016 Dec 7;4:21. eCollection 2016.

10.

Glucose induced activation of canonical Wnt signaling pathway in hepatocellular carcinoma is regulated by DKK4.

Chouhan S, Singh S, Athavale D, Ramteke P, Pandey V, Joseph J, Mohan R, Shetty PK, Bhat MK.

Sci Rep. 2016 Jun 8;6:27558. doi: 10.1038/srep27558.

11.

Prolonged exposure to insulin with insufficient glucose leads to impaired Glut4 translocation.

Khalique A, Sarwade RD, Pandey PR, Vijayakumar MV, Bhat MK, Seshadri V.

Biochem Biophys Res Commun. 2016 May 20;474(1):64-70. doi: 10.1016/j.bbrc.2016.04.066. Epub 2016 Apr 20.

12.

AMPK, a key regulator of metabolic/energy homeostasis and mitochondrial biogenesis in cancer cells.

Chaube B, Bhat MK.

Cell Death Dis. 2016 Jan 14;7:e2044. doi: 10.1038/cddis.2015.404. No abstract available.

13.

Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment.

Singh SV, Ajay AK, Mohammad N, Malvi P, Chaube B, Meena AS, Bhat MK.

Cell Death Dis. 2015 Oct 22;6:e1934. doi: 10.1038/cddis.2015.292.

14.

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.

Chaube B, Malvi P, Singh SV, Mohammad N, Meena AS, Bhat MK.

Oncotarget. 2015 Nov 10;6(35):37281-99. doi: 10.18632/oncotarget.6134.

15.

Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex.

Mohammad N, Singh SV, Malvi P, Chaube B, Athavale D, Vanuopadath M, Nair SS, Nair B, Bhat MK.

Sci Rep. 2015 Jul 7;5:11853. doi: 10.1038/srep11853.

16.

AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis.

Chaube B, Malvi P, Singh SV, Mohammad N, Viollet B, Bhat MK.

Cell Death Discov. 2015 Dec 21;1:15063. doi: 10.1038/cddiscovery.2015.63. eCollection 2015.

17.

Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: role of adipokines.

Malvi P, Chaube B, Pandey V, Vijayakumar MV, Boreddy PR, Mohammad N, Singh SV, Bhat MK.

Mol Oncol. 2015 Mar;9(3):689-703. doi: 10.1016/j.molonc.2014.11.006. Epub 2014 Nov 26.

18.

High fat diet promotes achievement of peak bone mass in young rats.

Malvi P, Piprode V, Chaube B, Pote ST, Mittal M, Chattopadhyay N, Wani MR, Bhat MK.

Biochem Biophys Res Commun. 2014 Dec 5;455(1-2):133-8.

PMID:
25450704
19.

Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma.

Mohammad N, Malvi P, Meena AS, Singh SV, Chaube B, Vannuruswamy G, Kulkarni MJ, Bhat MK.

Mol Cancer. 2014 Sep 1;13:204. doi: 10.1186/1476-4598-13-204.

20.

Genome Sequences of Four Clinical Staphylococcus aureus Strains with Diverse Drug Resistance Profiles Isolated from Diabetic Foot Ulcers.

Murali TS, Paul B, Parikh H, Singh RP, Kavitha S, Bhat MK, Satyamoorthy K.

Genome Announc. 2014 Mar 20;2(2). pii: e00204-14. doi: 10.1128/genomeA.00204-14.

21.

Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene.

Phani NM, Acharya S, Xavy S, Bhaskaranand N, Bhat MK, Jain A, Rai PS, Satyamoorthy K.

Gene. 2014 Feb 25;536(2):247-53. doi: 10.1016/j.gene.2013.12.026. Epub 2013 Dec 27. Erratum in: Gene. 2014 Apr 15;539(2):285. Kapaettu, Satyamoorthy [corrected to Satyamoorthy, Kapaettu].

PMID:
24378235
22.

Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved.

Meena AS, Sharma A, Kumari R, Mohammad N, Singh SV, Bhat MK.

PLoS One. 2013 Apr 16;8(4):e61524. doi: 10.1371/journal.pone.0061524. Print 2013.

23.

PAOO technique for the bimaxillary protrusion: Perio-ortho interrelationship.

Bhat SG, Singh V, Bhat MK.

J Indian Soc Periodontol. 2012 Oct;16(4):584-7. doi: 10.4103/0972-124X.106920.

24.

Real time qualitative and quantitative GLUT4 translocation assay.

Vijayakumar MV, Bhat MK.

Methods Enzymol. 2012;505:257-71. doi: 10.1016/B978-0-12-388448-0.00022-X.

PMID:
22289458
25.

Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells.

Ajay AK, Meena AS, Bhat MK.

Cell Biosci. 2012 Jan 13;2:2. doi: 10.1186/2045-3701-2-2.

26.

Enhancement of carboplatin- and quercetin-induced cell death by roscovitine is Akt dependent and p53 independent in hepatoma cells.

Sharma A, Bhat MK.

Integr Cancer Ther. 2011 Dec;10(4):NP4-14. doi: 10.1177/1534735411423922. Epub 2011 Oct 11.

PMID:
21994207
27.

Synthesis, characterization, plasmid cleavage and cytotoxicity of cancer cells by a copper(II) complex of anthracenyl-terpyridine.

Kumar A, Chinta JP, Ajay AK, Bhat MK, Rao CP.

Dalton Trans. 2011 Nov 7;40(41):10865-72. doi: 10.1039/c1dt10201j. Epub 2011 Jun 28.

PMID:
21709916
28.

Hyperglycemia regulates MDR-1, drug accumulation and ROS levels causing increased toxicity of carboplatin and 5-fluorouracil in MCF-7 cells.

Pandey V, Chaube B, Bhat MK.

J Cell Biochem. 2011 Oct;112(10):2942-52. doi: 10.1002/jcb.23210.

PMID:
21630327
29.

Diet-induced obesity increases melanoma progression: involvement of Cav-1 and FASN.

Pandey V, Vijayakumar MV, Ajay AK, Malvi P, Bhat MK.

Int J Cancer. 2012 Feb 1;130(3):497-508. doi: 10.1002/ijc.26048. Epub 2011 Apr 27.

30.
31.

Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression.

Ajay AK, Upadhyay AK, Singh S, Vijayakumar MV, Kumari R, Pandey V, Boppana R, Bhat MK.

Mol Cancer. 2010 Jul 31;9:204. doi: 10.1186/1476-4598-9-204.

32.

Hyperthermia-associated carboplatin resistance: differential role of p53, HSF1 and Hsp70 in hepatoma cells.

Sharma A, Meena AS, Bhat MK.

Cancer Sci. 2010 May;101(5):1186-93. doi: 10.1111/j.1349-7006.2010.01516.x. Epub 2010 Jan 28.

33.

Cytotoxic activity of 9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol from Eulophia nuda against human cancer cells.

Shriram V, Kumar V, Kishor PB, Suryawanshi SB, Upadhyay AK, Bhat MK.

J Ethnopharmacol. 2010 Mar 2;128(1):251-3. doi: 10.1016/j.jep.2009.12.031. Epub 2010 Jan 4.

PMID:
20045453
34.

Inhibition of Hsp27 and Hsp40 potentiates 5-fluorouracil and carboplatin mediated cell killing in hepatoma cells.

Sharma A, Upadhyay AK, Bhat MK.

Cancer Biol Ther. 2009 Nov;8(22):2106-13. Epub 2009 Nov 3.

PMID:
19901540
35.

Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor.

Vijayakumar MV, Pandey V, Mishra GC, Bhat MK.

Obesity (Silver Spring). 2010 Apr;18(4):667-74. doi: 10.1038/oby.2009.337. Epub 2009 Oct 22.

36.

Mitomycin C induces bystander killing in homogeneous and heterogeneous hepatoma cellular models.

Kumari R, Sharma A, Ajay AK, Bhat MK.

Mol Cancer. 2009 Oct 21;8:87. doi: 10.1186/1476-4598-8-87.

37.

Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole analogues.

Aher NG, Pore VS, Mishra NN, Kumar A, Shukla PK, Sharma A, Bhat MK.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):759-63. doi: 10.1016/j.bmcl.2008.12.026. Epub 2008 Dec 10.

PMID:
19110424
38.

Cell cycle regulatory protein 5 (Cdk5) is a novel downstream target of ERK in carboplatin induced death of breast cancer cells.

Upadhyay AK, Ajay AK, Singh S, Bhat MK.

Curr Cancer Drug Targets. 2008 Dec;8(8):741-52.

PMID:
19075597
39.

Atomic force microscopy, biochemical analysis of 3T3-L1 cells differentiated in the absence and presence of insulin.

Pandey V, Vijayakumar MV, Kaul-Ghanekar R, Mamgain H, Paknikar K, Bhat MK.

Biochim Biophys Acta. 2009 Jan 1;1790(1):57-64. doi: 10.1016/j.bbagen.2008.08.008. Epub 2008 Sep 6.

PMID:
18809467
40.
41.

Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation.

Chhipa RR, Kumari R, Upadhyay AK, Bhat MK.

Exp Cell Res. 2007 Nov 15;313(19):3945-58. Epub 2007 Sep 4.

PMID:
17935714
42.

Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and its analogues.

Gholap AR, Toti KS, Shirazi F, Kumari R, Bhat MK, Deshpande MV, Srinivasan KV.

Bioorg Med Chem. 2007 Nov 1;15(21):6705-15. Epub 2007 Aug 15.

PMID:
17765545
43.

Role of transglycosylation products in the expression of multiple xylanases in Myceliophthora sp. IMI 387099.

Badhan AK, Chadha BS, Kaur J, Sonia KG, Saini HS, Bhat MK.

Curr Microbiol. 2007 Jun;54(6):405-9. Epub 2007 May 14.

PMID:
17503151
44.
45.

p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.

Singh S, Upadhyay AK, Ajay AK, Bhat MK.

FEBS Lett. 2007 Jan 23;581(2):289-95. Epub 2006 Dec 29.

46.

Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells.

Singh S, Upadhyay AK, Ajay AK, Bhat MK.

J Cell Biochem. 2007 Apr 1;100(5):1191-9.

PMID:
17063488
47.
48.

Methyl-beta-cyclodextrin enhances the susceptibility of human breast cancer cells to carboplatin and 5-fluorouracil: involvement of Akt, NF-kappaB and Bcl-2.

Upadhyay AK, Singh S, Chhipa RR, Vijayakumar MV, Ajay AK, Bhat MK.

Toxicol Appl Pharmacol. 2006 Oct 15;216(2):177-85. Epub 2006 May 19.

PMID:
16806341
49.

Diversity of plant cell wall esterases in thermophilic and thermotolerant fungi.

Ghatora SK, Chadha BS, Saini HS, Bhat MK, Faulds CB.

J Biotechnol. 2006 Sep 18;125(3):434-45. Epub 2006 May 19.

PMID:
16713648
50.

Update of radiosurgery at the Royal Adelaide Hospital.

Roos DE, Brophy BP, Bhat MK, Katsilis ES.

Australas Radiol. 2006 Apr;50(2):158-67.

PMID:
16635035

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