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Items: 1 to 50 of 72

1.

The Flavonoid Metabolite 2,4,6-Trihydroxybenzoic Acid Is a CDK Inhibitor and an Anti-Proliferative Agent: A Potential Role in Cancer Prevention.

Sankaranarayanan R, Valiveti CK, Kumar DR, Van Slambrouck S, Kesharwani SS, Seefeldt T, Scaria J, Tummala H, Bhat GJ.

Cancers (Basel). 2019 Mar 26;11(3). pii: E427. doi: 10.3390/cancers11030427.

2.

Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer.

Dachineni R, Kumar DR, Callegari E, Kesharwani SS, Sankaranarayanan R, Seefeldt T, Tummala H, Bhat GJ.

Int J Oncol. 2017 Dec;51(6):1661-1673. doi: 10.3892/ijo.2017.4167. Epub 2017 Oct 19.

3.

In Vitro and In Vivo Tumor Growth Inhibition by Glutathione Disulfide Liposomes.

Sadhu SS, Wang S, Dachineni R, Averineni RK, Yang Y, Yin H, Bhat GJ, Guan X.

Cancer Growth Metastasis. 2017 Mar 10;10:1179064417696070. doi: 10.1177/1179064417696070. eCollection 2017.

4.

In Vitro and In Vivo Antimetastatic Effect of Glutathione Disulfide Liposomes.

Sadhu SS, Wang S, Dachineni R, Averineni RK, Seefeldt T, Xie J, Tummala H, Bhat GJ, Guan X.

Cancer Growth Metastasis. 2017 Mar 8;10:1179064417695255. doi: 10.1177/1179064417695255. eCollection 2017.

5.

Aspirin inhibits glucose‑6‑phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites.

Ai G, Dachineni R, Kumar DR, Alfonso LF, Marimuthu S, Bhat GJ.

Mol Med Rep. 2016 Aug;14(2):1726-32. doi: 10.3892/mmr.2016.5449. Epub 2016 Jun 27.

6.

Cyclin A2 and CDK2 as Novel Targets of Aspirin and Salicylic Acid: A Potential Role in Cancer Prevention.

Dachineni R, Ai G, Kumar DR, Sadhu SS, Tummala H, Bhat GJ.

Mol Cancer Res. 2016 Mar;14(3):241-52. doi: 10.1158/1541-7786.MCR-15-0360. Epub 2015 Dec 18.

7.

Aspirin acetylates wild type and mutant p53 in colon cancer cells: identification of aspirin acetylated sites on recombinant p53.

Ai G, Dachineni R, Kumar DR, Marimuthu S, Alfonso LF, Bhat GJ.

Tumour Biol. 2016 May;37(5):6007-16. doi: 10.1007/s13277-015-4438-3. Epub 2015 Nov 23.

PMID:
26596838
8.

Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin.

Kumar S, Kesharwani SS, Mathur H, Tyagi M, Bhat GJ, Tummala H.

Eur J Pharm Sci. 2016 Jan 20;82:86-96. doi: 10.1016/j.ejps.2015.11.010. Epub 2015 Nov 15.

PMID:
26588875
9.

Aspirin and salicylic acid decrease c-Myc expression in cancer cells: a potential role in chemoprevention.

Ai G, Dachineni R, Muley P, Tummala H, Bhat GJ.

Tumour Biol. 2016 Feb;37(2):1727-38. doi: 10.1007/s13277-015-3959-0. Epub 2015 Aug 28.

PMID:
26314861
10.

Molecular targets of aspirin and cancer prevention.

Alfonso L, Ai G, Spitale RC, Bhat GJ.

Br J Cancer. 2014 Jul 8;111(1):61-7. doi: 10.1038/bjc.2014.271. Epub 2014 May 29. Review.

11.

Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice.

Vad NM, Kudugunti SK, Wang H, Bhat GJ, Moridani MY.

Tumour Biol. 2014 May;35(5):4967-76. doi: 10.1007/s13277-014-1654-1. Epub 2014 Feb 4.

PMID:
24492939
12.

Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets.

Marimuthu S, Chivukula RS, Alfonso LF, Moridani M, Hagen FK, Bhat GJ.

Int J Oncol. 2011 Nov;39(5):1273-83. doi: 10.3892/ijo.2011.1113. Epub 2011 Jul 4.

PMID:
21743961
13.

Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines.

Yusuf MA, Chuang T, Bhat GJ, Srivenugopal KS.

Free Radic Biol Med. 2010 Sep 1;49(5):908-17. doi: 10.1016/j.freeradbiomed.2010.06.020. Epub 2010 Jun 25.

14.

Does aspirin acetylate multiple cellular proteins? (Review).

Alfonso LF, Srivenugopal KS, Bhat GJ.

Mol Med Rep. 2009 Jul-Aug;2(4):533-7. doi: 10.3892/mmr_00000132.

PMID:
21475861
15.

Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells.

Alfonso LF, Srivenugopal KS, Arumugam TV, Abbruscato TJ, Weidanz JA, Bhat GJ.

Int J Oncol. 2009 Mar;34(3):597-608.

PMID:
19212664
16.

A functional role for sodium-dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation.

Vemula S, Roder KE, Yang T, Bhat GJ, Thekkumkara TJ, Abbruscato TJ.

J Pharmacol Exp Ther. 2009 Feb;328(2):487-95. doi: 10.1124/jpet.108.146589. Epub 2008 Nov 3.

17.

Angiotensin II induces phosphorylation of glucose-regulated protein-75 in WB rat liver cells.

Krishna SB, Alfonso LF, Thekkumkara TJ, Abbruscato TJ, Bhat GJ.

Arch Biochem Biophys. 2007 Jan 1;457(1):16-28. Epub 2006 Nov 2.

18.

Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines.

Niture SK, Velu CS, Smith QR, Bhat GJ, Srivenugopal KS.

Carcinogenesis. 2007 Feb;28(2):378-89. Epub 2006 Aug 31.

PMID:
16950796
19.

Influencing sexual practices among HIV-positive Zambian women.

Jones DL, Weiss SM, Bhat GJ, Bwalya V.

AIDS Care. 2006 Aug;18(6):629-34.

20.

Acute effect of high glucose on long-term cell growth: a role for transient glucose increase in proximal tubule cell injury.

Samikkannu T, Thomas JJ, Bhat GJ, Wittman V, Thekkumkara TJ.

Am J Physiol Renal Physiol. 2006 Jul;291(1):F162-75. Epub 2006 Feb 7.

21.

Protein kinase C family members as a target for regulation of blood-brain barrier Na,K,2Cl-cotransporter during in vitro stroke conditions and nicotine exposure.

Yang T, Roder KE, Bhat GJ, Thekkumkara TJ, Abbruscato TJ.

Pharm Res. 2006 Feb;23(2):291-302. Epub 2006 Feb 7.

PMID:
16450214
22.

Infectious molecular clone of a recently transmitted pediatric human immunodeficiency virus clade C isolate from Africa: evidence of intraclade recombination.

Grisson RD, Chenine AL, Yeh LY, He J, Wood C, Bhat GJ, Xu W, Kankasa C, Ruprecht RM.

J Virol. 2004 Dec;78(24):14066-9.

23.

Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): a double-blind randomised placebo-controlled trial.

Chintu C, Bhat GJ, Walker AS, Mulenga V, Sinyinza F, Lishimpi K, Farrelly L, Kaganson N, Zumla A, Gillespie SH, Nunn AJ, Gibb DM; CHAP trial team.

Lancet. 2004 Nov 20-26;364(9448):1865-71.

PMID:
15555666
24.

alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.

Bhat GJ, Samikkannu T, Thomas JJ, Thekkumkara TJ.

J Biol Chem. 2004 Nov 19;279(47):48915-22. Epub 2004 Sep 13.

25.

A Sexual Barrier Intervention for HIV+/- Zambian Women: Acceptability and Use of Vaginal Chemical Barriers.

Jones DL, Weiss SM, Bhat GJ, Feldman D, Bwalya V, Budash D.

J Multicult Nurs Health. 2004 Jan 1;10(1):24-31.

26.

Infant-feeding practices of mothers of known HIV status in Lusaka, Zambia.

Omari AA, Luo C, Kankasa C, Bhat GJ, Bunn J.

Health Policy Plan. 2003 Jun;18(2):156-62.

PMID:
12740320
27.

Pseudomonas aeruginosa elastase stimulates ERK signaling pathway and enhances IL-8 production by alveolar epithelial cells in culture.

Azghani AO, Baker JW, Shetty S, Miller EJ, Bhat GJ.

Inflamm Res. 2002 Oct;51(10):506-10.

PMID:
12477080
28.
29.

Potent neutralization of primary human immunodeficiency virus clade C isolates with a synergistic combination of human monoclonal antibodies raised against clade B.

Xu W, Smith-Franklin BA, Li PL, Wood C, He J, Du Q, Bhat GJ, Kankasa C, Katinger H, Cavacini LA, Posner MR, Burton DR, Chou TC, Ruprecht RM.

J Hum Virol. 2001 Mar-Apr;4(2):55-61.

PMID:
11437315
30.
31.

A randomized controlled trial of artemotil (beta-arteether) in Zambian children with cerebral malaria.

Thuma PE, Bhat GJ, Mabeza GF, Osborne C, Biemba G, Shakankale GM, Peeters PA, Oosterhuis B, Lugt CB, Gordeuk VR.

Am J Trop Med Hyg. 2000 Apr;62(4):524-9.

PMID:
11220772
32.

Rapid voluntary testing and counseling for HIV. Acceptability and feasibility in Zambian antenatal care clinics.

Bakari JP, McKenna S, Myrick A, Mwinga K, Bhat GJ, Allen S.

Ann N Y Acad Sci. 2000 Nov;918:64-76.

PMID:
11131736
33.
34.

Urokinase-type plasminogen activator induces tyrosine phosphorylation of a 78-kDa protein in H-157 cells.

Bhat GJ, Gunaje JJ, Idell S.

Am J Physiol. 1999 Aug;277(2):L301-9. doi: 10.1152/ajplung.1999.277.2.L301.

PMID:
10444524
35.

Individuals from North America, Australasia, and Africa are infected with four different genotypes of human herpesvirus 8.

Meng YX, Spira TJ, Bhat GJ, Birch CJ, Druce JD, Edlin BR, Edwards R, Gunthel C, Newton R, Stamey FR, Wood C, Pellett PE.

Virology. 1999 Aug 15;261(1):106-19.

36.

alpha-thrombin inhibits interleukin-6-induced Stat3 signaling and gp130 gene expression in primary cultures of human lung fibroblasts.

Bhat GJ, Raghu G, Gunaje JJ, Idell S.

Biochem Biophys Res Commun. 1999 Mar 24;256(3):626-30.

PMID:
10080949
37.

Cross-talk between angiotensin II and interleukin-6-induced signaling through Stat3 transcription factor.

Bhat GJ, Baker KM.

Basic Res Cardiol. 1998;93 Suppl 3:26-9. Review.

PMID:
9879441
38.

Randomised study of skin-to-skin versus incubator care for rewarming low-risk hypothermic neonates.

Christensson K, Bhat GJ, Amadi BC, Eriksson B, Höjer B.

Lancet. 1998 Oct 3;352(9134):1115. No abstract available.

PMID:
9798589
39.

Effect of iron chelation therapy on mortality in Zambian children with cerebral malaria.

Thuma PE, Mabeza GF, Biemba G, Bhat GJ, McLaren CE, Moyo VM, Zulu S, Khumalo H, Mabeza P, M'Hango A, Parry D, Poltera AA, Brittenham GM, Gordeuk VR.

Trans R Soc Trop Med Hyg. 1998 Mar-Apr;92(2):214-8.

PMID:
9764337
41.

Molecular mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and signal transduction pathways.

Dostal DE, Hunt RA, Kule CE, Bhat GJ, Karoor V, McWhinney CD, Baker KM.

J Mol Cell Cardiol. 1997 Nov;29(11):2893-902. Review.

PMID:
9405164
42.

Angiotensin II stimulates rapid serine phosphorylation of transcription factor Stat3.

Bhat GJ, Baker KM.

Mol Cell Biochem. 1997 May;170(1-2):171-6.

PMID:
9144332
43.

Alpha-thrombin stimulates sis-inducing factor-A DNA binding activity in rat aortic smooth muscle cells.

Bhat GJ, Abraham ST, Singer HA, Baker KM.

Hypertension. 1997 Jan;29(1 Pt 2):356-60.

PMID:
9039127
44.
45.

Activation of the STAT pathway by angiotensin II in T3CHO/AT1A cells. Cross-talk between angiotensin II and interleukin-6 nuclear signaling.

Bhat GJ, Thekkumkara TJ, Thomas WG, Conrad KM, Baker KM.

J Biol Chem. 1995 Aug 11;270(32):19059-65.

46.

The effect of routine hospital care on the health of hypothermic newborn infants in Zambia.

Christensson K, Bhat GJ, Eriksson B, Shilalukey-Ngoma MP, Sterky G.

J Trop Pediatr. 1995 Aug;41(4):210-4. doi: 10.1093/tropej/41.4.210.

PMID:
7563272
47.

Measles infection in hospitalized children in Lusaka, Zambia.

Oshitani H, Mpabalwani M, Kasolo F, Mizuta K, Luo NP, Bhat GJ, Suzuki H, Numazaki Y.

Ann Trop Paediatr. 1995 Jun;15(2):167-72.

PMID:
7677420
48.
49.

HIV, BCG and TB in children: a case control study in Lusaka, Zambia.

Bhat GJ, Diwan VK, Chintu C, Kabika M, Masona J.

J Trop Pediatr. 1993 Aug;39(4):219-23. doi: 10.1093/tropej/39.4.219.

PMID:
8411315
50.

Transcript-specific developmental regulation of polyadenylation in Trypanosoma brucei mitochondria.

Bhat GJ, Souza AE, Feagin JE, Stuart K.

Mol Biochem Parasitol. 1992 Jun;52(2):231-40.

PMID:
1352374

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