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Items: 50

1.

Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.

Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ.

Oncotarget. 2019 Feb 22;10(16):1603. doi: 10.18632/oncotarget.26743. eCollection 2019 Feb 22.

2.

Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.

Kasembeli MM, Bharadwaj U, Robinson P, Tweardy DJ.

Int J Mol Sci. 2018 Aug 5;19(8). pii: E2299. doi: 10.3390/ijms19082299. Review.

3.

Impact of chronic hepatitis C virus infection on the survival of patients with oropharyngeal cancer.

Economides MP, Amit M, Mahale PS, Hosry JJ, Jiang Y, Bharadwaj U, Sturgis EM, Torres HA.

Cancer. 2018 Mar 1;124(5):960-965. doi: 10.1002/cncr.31146. Epub 2017 Nov 17.

4.

Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.

Singh M, Vianden C, Cantwell MJ, Dai Z, Xiao Z, Sharma M, Khong H, Jaiswal AR, Faak F, Hailemichael Y, Janssen LME, Bharadwaj U, Curran MA, Diab A, Bassett RL, Tweardy DJ, Hwu P, Overwijk WW.

Nat Commun. 2017 Nov 13;8(1):1447. doi: 10.1038/s41467-017-01572-7.

5.

Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.

Jung KH, Yoo W, Stevenson HL, Deshpande D, Shen H, Gagea M, Yoo SY, Wang J, Eckols TK, Bharadwaj U, Tweardy DJ, Beretta L.

Clin Cancer Res. 2017 Sep 15;23(18):5537-5546. doi: 10.1158/1078-0432.CCR-16-2253. Epub 2017 May 22.

6.

STAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma model.

Gavino AC, Nahmod K, Bharadwaj U, Makedonas G, Tweardy DJ.

Allergy. 2016 Dec;71(12):1684-1692. doi: 10.1111/all.12937. Epub 2016 Jun 23.

PMID:
27225906
7.

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.

Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ.

Oncotarget. 2016 May 3;7(18):26307-30. doi: 10.18632/oncotarget.8368. Erratum in: Oncotarget. 2019 Feb 22;10(16):1603.

8.

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance.

Robinson P, Kasembeli M, Bharadwaj U, Engineer N, Eckols KT, Tweardy DJ.

Biomed Res Int. 2016;2016:1959270. doi: 10.1155/2016/1959270. Epub 2016 Feb 11.

9.

A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture.

Zheng M, Turton KB, Zhu F, Li Y, Grindle KM, Annis DS, Lu L, Drennan AC, Tweardy DJ, Bharadwaj U, Mosher DF, Rui L.

Oncogenesis. 2016 Jan 4;4:e184. doi: 10.1038/oncsis.2015.44.

10.

Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF.

PLoS One. 2016 Jan 4;11(1):e0146626. doi: 10.1371/journal.pone.0146626. eCollection 2016. No abstract available.

11.

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species.

Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF.

PLoS One. 2015 Dec 8;10(12):e0143964. doi: 10.1371/journal.pone.0143964. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0146626. Zhou, Mingzhao [corrected to Zhu, Mingzhao].

12.

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.

Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJ.

Lung Cancer. 2015 Nov;90(2):182-90. doi: 10.1016/j.lungcan.2015.09.014. Epub 2015 Sep 15.

13.

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.

Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ.

Cancers (Basel). 2014 Sep 29;6(4):2012-34. doi: 10.3390/cancers6042012.

14.

Associations of killer cell immunoglobulin like receptors with rheumatoid arthritis among North Indian population.

Prakash S, Alam S, Bharadwaj U, Aggarwal A, Mishra RN, Agrawal S.

Hum Immunol. 2014 Aug;75(8):802-7. doi: 10.1016/j.humimm.2014.05.014. Epub 2014 Jun 6.

PMID:
24912006
15.

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ.

Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31.

16.

A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer.

Marin-Muller C, Li D, Bharadwaj U, Li M, Chen C, Hodges SE, Fisher WE, Mo Q, Hung MC, Yao Q.

Clin Cancer Res. 2013 Nov 1;19(21):5901-13. doi: 10.1158/1078-0432.CCR-12-3776. Epub 2013 Aug 29.

17.

A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.

Elsarraj HS, Hong Y, Valdez K, Carletti M, Salah SM, Raimo M, Taverna D, Prochasson P, Bharadwaj U, Tweardy DJ, Christenson LK, Behbod F.

J Cell Sci. 2013 Jun 1;126(Pt 11):2446-58. doi: 10.1242/jcs.119214. Epub 2013 Apr 9.

18.

Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression.

Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q.

Mol Cancer. 2011 Aug 31;10:106. doi: 10.1186/1476-4598-10-106.

19.

Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation.

Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q.

Carcinogenesis. 2011 Jul;32(7):1013-24. doi: 10.1093/carcin/bgr075. Epub 2011 Apr 23.

20.

Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans.

Lay MK, Atmar RL, Guix S, Bharadwaj U, He H, Neill FH, Sastry KJ, Yao Q, Estes MK.

Virology. 2010 Oct 10;406(1):1-11. doi: 10.1016/j.virol.2010.07.001. Epub 2010 Jul 29.

21.

Effect of copper- and zinc-methionine supplementation on bioavailability, mineral status and tissue concentrations of copper and zinc in ewes.

Pal DT, Gowda NK, Prasad CS, Amarnath R, Bharadwaj U, Suresh Babu G, Sampath KT.

J Trace Elem Med Biol. 2010 Apr;24(2):89-94. doi: 10.1016/j.jtemb.2009.11.007. Epub 2010 Jan 13.

PMID:
20413065
22.

ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB.

Zhang Y, Bharadwaj U, Logsdon CD, Chen C, Yao Q, Li M.

Clin Cancer Res. 2010 Mar 1;16(5):1423-30. doi: 10.1158/1078-0432.CCR-09-2405. Epub 2010 Feb 16.

23.

Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts.

Li M, Zhang Y, Bharadwaj U, Zhai QJ, Ahern CH, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q.

Clin Cancer Res. 2009 Oct 1;15(19):5993-6001. doi: 10.1158/1078-0432.CCR-09-0557. Epub 2009 Sep 15.

24.

MicroRNAs: control and loss of control in human physiology and disease.

Li M, Marin-Muller C, Bharadwaj U, Chow KH, Yao Q, Chen C.

World J Surg. 2009 Apr;33(4):667-84. doi: 10.1007/s00268-008-9836-x. Review.

25.
26.

Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells.

Chen C, Chai H, Wang X, Jiang J, Jamaluddin MS, Liao D, Zhang Y, Wang H, Bharadwaj U, Zhang S, Li M, Lin P, Yao Q.

Blood. 2008 Oct 15;112(8):3205-16. doi: 10.1182/blood-2008-03-143479. Epub 2008 Jul 24.

27.

Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer.

Li M, Bharadwaj U, Zhang R, Zhang S, Mu H, Fisher WE, Brunicardi FC, Chen C, Yao Q.

Mol Cancer Ther. 2008 Feb;7(2):286-96. doi: 10.1158/1535-7163.MCT-07-0483.

28.

C-reactive protein inhibits cholesterol efflux from human macrophage-derived foam cells.

Wang X, Liao D, Bharadwaj U, Li M, Yao Q, Chen C.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):519-26. Epub 2007 Dec 20.

29.

Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.

Li M, Zhang Y, Liu Z, Bharadwaj U, Wang H, Wang X, Zhang S, Liuzzi JP, Chang SM, Cousins RJ, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18636-41. Epub 2007 Nov 14.

30.

Human genetic variation studies and HLA class II loci.

Agrawal S, Khan F, Bharadwaj U.

Int J Immunogenet. 2007 Aug;34(4):247-52.

PMID:
17627759
31.

IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells.

Feurino LW, Zhang Y, Bharadwaj U, Zhang R, Li F, Fisher WE, Brunicardi FC, Chen C, Yao Q, Min L.

Cancer Biol Ther. 2007 Jul;6(7):1096-100.

PMID:
17568185
32.
33.

Thymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes.

Yao Q, Doan LX, Zhang R, Bharadwaj U, Li M, Chen C.

Immunol Lett. 2007 Jun 15;110(2):110-20. Epub 2007 May 15.

34.
35.

Effects of pentoxifylline on differentiation, maturation, and function of human CD14+ monocyte-derived dendritic cells.

Zhang R, Bharadwaj U, Li M, Chen C, Yao Q.

J Immunother. 2007 Jan;30(1):89-95.

PMID:
17198087
36.

Current update of cytokines in pancreatic cancer: pathogenic mechanisms, clinical indication, and therapeutic values.

Feurino LW, Fisher WE, Bharadwaj U, Yao Q, Chen C, Li M.

Cancer Invest. 2006 Nov;24(7):696-703. Review.

PMID:
17118780
37.

Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147.

Li M, Zhai Q, Bharadwaj U, Wang H, Li F, Fisher WE, Chen C, Yao Q.

Cancer. 2006 May 15;106(10):2284-94.

38.

Effects of cyclophilin A on myeloblastic cell line KG-1 derived dendritic like cells (DLC) through p38 MAP kinase activation.

Bharadwaj U, Zhang R, Yang H, Li M, Doan LX, Chen C, Yao Q.

J Surg Res. 2005 Jul 1;127(1):29-38. Epub 2005 Apr 21.

PMID:
15964302
39.

High frequency of type 1B (idiopathic) diabetes in North Indian children with recent-onset diabetes.

Balasubramanian K, Dabadghao P, Bhatia V, Colman PG, Gellert SA, Bharadwaj U, Agrawal S, Shah N, Bhatia E.

Diabetes Care. 2003 Sep;26(9):2697. No abstract available.

PMID:
12941746
40.

Microsatellite variation at 24 STR loci in three endogamous groups of Uttar Pradesh, India.

Agrawal S, Müller B, Bharadwaj U, Bhatnagar S, Sharma A, Khan F, Agarwal SS.

Hum Biol. 2003 Feb;75(1):97-104.

PMID:
12713150
41.

Evaluation of six short tandem repeat loci in forensics: north Indian populations.

Agrawal S, Müller B, Bharadwaj U, Bhatnagar S, Khan F.

J Forensic Sci. 2002 May;47(3):686-9. No abstract available.

PMID:
12051367
42.

Distribution of allele frequencies of six STR markers in north Indians.

Agrawal S, Müller B, Bharadwaj U, Bhatnagar S, Khan F.

J Forensic Sci. 2002 May;47(3):682-5. No abstract available.

PMID:
12051366
43.

Allele frequencies of microsatellite repeat loci in Bhargavas, Chaturvedis, and Brahmins of North India.

Agrawal S, Müller B, Bharadwaj U, Bhatnagar S, Khan F.

J Forensic Sci. 2002 May;47(3):678-81. No abstract available.

PMID:
12051365
44.

DNA short tandem repeat profiling of three North Indian populations.

Agrawal S, Müller B, Bharadwaj U, Bhatnagar S, Sharma A, Khan F, Agarwal SS.

J Forensic Sci. 2001 Nov;46(6):1523-5.

PMID:
11714177
45.

Central cholinergic mechanism for control of urine volume and electrolyte excretion.

Misra V, Bapat SK, Bharadwaj UR, Saxena VC, Singh KN.

Indian J Physiol Pharmacol. 1977 Jul-Sep;21(3):203-6.

PMID:
612604
46.

Effect of centrally administered glucagon on urine output in dogs.

Agarwala GC, Mittal RK, Bapat SK, Bharadwaj UR.

Indian J Physiol Pharmacol. 1976 Oct-Dec;20(4):209-15.

PMID:
1010636
47.

Centrally mediated pressor response of angiotensin II in dogs.

Singh KN, Varma S, Bharadwaj UR, Ghildyal SK.

Indian J Med Res. 1976 Jan;64(1):138-43. No abstract available.

PMID:
1270094
48.

Central component of the cario-accelerator action of angiotensin II in dogs.

Varma S, Singh KN, Bharadwaj UR.

Indian J Physiol Pharmacol. 1975 Oct-Dec;19(4):173-80.

PMID:
1222993
49.

Repletion studies on liver proteins and liver enzymes by feeding some wild leguminous seed protein isolates.

Yadav NR, Bharadwaj UR.

J Indian Med Assoc. 1973 Feb 1;60(3):93-5. No abstract available.

PMID:
4720093
50.

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