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Items: 1 to 20 of 47

1.

A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins.

Sidoli S, Lopes M, Lund PJ, Goldman N, Fasolino M, Coradin M, Kulej K, Bhanu NV, Vahedi G, Garcia BA.

Sci Rep. 2019 Sep 20;9(1):13613. doi: 10.1038/s41598-019-49894-4.

2.

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.

Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG.

Blood. 2019 Oct 3;134(14):1176-1189. doi: 10.1182/blood.2019000578. Epub 2019 Aug 5.

PMID:
31383640
3.

Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription.

Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA.

Cell Rep. 2019 Apr 9;27(2):400-415.e5. doi: 10.1016/j.celrep.2019.03.057.

4.

Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis.

Bhanu NV, Sidoli S, Yuan ZF, Molden RC, Garcia BA.

J Biol Chem. 2019 May 17;294(20):8296-8308. doi: 10.1074/jbc.RA118.004977. Epub 2019 Mar 14.

PMID:
30872405
5.

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.

Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I.

Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13.

6.

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.

Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, Bhanu NV, Simithy J, Patel B, Huang J, Raynal NJ, Garcia BA, Jacobson MA, Kadoch C, Merali S, Zhang Y, Childers W, Abou-Gharbia M, Karanicolas J, Baylin SB, Zahnow CA, Jelinek J, Graña X, Issa JJ.

Cell. 2018 Nov 15;175(5):1244-1258.e26. doi: 10.1016/j.cell.2018.09.051. Epub 2018 Oct 25.

PMID:
30454645
7.

Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites.

Li ML, Jiang Q, Bhanu NV, Wu J, Li W, Garcia BA, Greenberg RA.

Mol Cell Biol. 2018 Dec 11;39(1). pii: e00209-18. doi: 10.1128/MCB.00209-18. Print 2019 Jan 1.

8.

An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules.

Woll KA, Guzik-Lendrum S, Bensel BM, Bhanu NV, Dailey WP, Garcia BA, Gilbert SP, Eckenhoff RG.

J Biol Chem. 2018 Jul 20;293(29):11283-11295. doi: 10.1074/jbc.RA118.002182. Epub 2018 May 29.

9.

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.

Lee CH, Yu JR, Kumar S, Jin Y, LeRoy G, Bhanu N, Kaneko S, Garcia BA, Hamilton AD, Reinberg D.

Mol Cell. 2018 May 3;70(3):422-434.e6. doi: 10.1016/j.molcel.2018.03.020. Epub 2018 Apr 19.

10.

Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors.

Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG.

FASEB J. 2018 Aug;32(8):4172-4189. doi: 10.1096/fj.201701347R. Epub 2018 Mar 5.

11.

Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming.

Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, Gorbunova V.

Stem Cell Reports. 2017 Nov 14;9(5):1721-1734. doi: 10.1016/j.stemcr.2017.10.001. Epub 2017 Oct 26.

12.

Characterization of histone acylations links chromatin modifications with metabolism.

Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA.

Nat Commun. 2017 Oct 26;8(1):1141. doi: 10.1038/s41467-017-01384-9.

13.

Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling.

Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R.

Biophys J. 2017 Nov 21;113(10):2168-2172. doi: 10.1016/j.bpj.2017.08.040. Epub 2017 Sep 19.

14.

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription.

Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D.

Nature. 2017 Jul 27;547(7664):463-467. doi: 10.1038/nature23267. Epub 2017 Jun 22.

15.

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.

Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, Pataer A, Swisher SG, Kalhor N, Bhanu NV, Garcia BA, Heymach JV, Coombes K, Xie Y, Girard L, Gazdar AF, Kittler R, Wistuba II, Minna JD, Martinez ED.

Cell Rep. 2017 May 23;19(8):1669-1684. doi: 10.1016/j.celrep.2017.04.077.

16.

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD 2nd, Garcia BA, Adelman K, Wysocka J.

Mol Cell. 2017 May 18;66(4):568-576.e4. doi: 10.1016/j.molcel.2017.04.018. Epub 2017 May 5.

17.

Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation.

Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG.

ACS Chem Biol. 2017 May 19;12(5):1353-1362. doi: 10.1021/acschembio.7b00222. Epub 2017 Apr 3.

PMID:
28333442
18.
19.

PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity.

Zhou B, Wang J, Lee SY, Xiong J, Bhanu N, Guo Q, Ma P, Sun Y, Rao RC, Garcia BA, Hess JL, Dou Y.

Mol Cell. 2016 Apr 21;62(2):222-236. doi: 10.1016/j.molcel.2016.03.010. Epub 2016 Apr 14.

20.

Folate deficiency affects histone methylation.

Garcia BA, Luka Z, Loukachevitch LV, Bhanu NV, Wagner C.

Med Hypotheses. 2016 Mar;88:63-7. doi: 10.1016/j.mehy.2015.12.027. Epub 2016 Jan 9.

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