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Items: 34

1.

Analytical Validation of Clinical Whole-Genome and Transcriptome Sequencing of Patient-Derived Tumors for Reporting Targetable Variants in Cancer.

Wrzeszczynski KO, Felice V, Abhyankar A, Kozon L, Geiger H, Manaa D, London F, Robinson D, Fang X, Lin D, Lamendola-Essel MF, Khaira D, Dikoglu E, Emde AK, Robine N, Shah M, Arora K, Basturk O, Bhanot U, Kentsis A, Mansukhani MM, Bhagat G, Jobanputra V.

J Mol Diagn. 2018 Nov;20(6):822-835. doi: 10.1016/j.jmoldx.2018.06.007. Epub 2018 Aug 21.

2.

Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.

Untch BR, Dos Anjos V, Garcia-Rendueles MER, Knauf JA, Krishnamoorthy GP, Saqcena M, Bhanot UK, Socci ND, Ho AL, Ghossein R, Fagin JA.

Cancer Res. 2018 Aug 15;78(16):4642-4657. doi: 10.1158/0008-5472.CAN-17-1925. Epub 2018 May 14.

3.

Non coding RNA analysis in fibrolamellar hepatocellular carcinoma.

Farber BA, Lalazar G, Simon EP, Hammond WJ, Requena D, Bhanot UK, La Quaglia MP, Simon SM.

Oncotarget. 2017 Dec 15;9(12):10211-10227. doi: 10.18632/oncotarget.23325. eCollection 2018 Feb 13.

4.

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

Balachandran VP, Łuksza M, Zhao JN, Makarov V, Moral JA, Remark R, Herbst B, Askan G, Bhanot U, Senbabaoglu Y, Wells DK, Cary CIO, Grbovic-Huezo O, Attiyeh M, Medina B, Zhang J, Loo J, Saglimbeni J, Abu-Akeel M, Zappasodi R, Riaz N, Smoragiewicz M, Kelley ZL, Basturk O; Australian Pancreatic Cancer Genome Initiative; Garvan Institute of Medical Research; Prince of Wales Hospital; Royal North Shore Hospital; University of Glasgow; St Vincent’s Hospital; QIMR Berghofer Medical Research Institute; University of Melbourne, Centre for Cancer Research; University of Queensland, Institute for Molecular Bioscience; Bankstown Hospital; Liverpool Hospital; Royal Prince Alfred Hospital, Chris O’Brien Lifehouse; Westmead Hospital; Fremantle Hospital; St John of God Healthcare; Royal Adelaide Hospital; Flinders Medical Centre; Envoi Pathology; Princess Alexandria Hospital; Austin Hospital; Johns Hopkins Medical Institutes; ARC-Net Centre for Applied Research on Cancer, Gönen M, Levine AJ, Allen PJ, Fearon DT, Merad M, Gnjatic S, Iacobuzio-Donahue CA, Wolchok JD, DeMatteo RP, Chan TA, Greenbaum BD, Merghoub T, Leach SD.

Nature. 2017 Nov 23;551(7681):512-516. doi: 10.1038/nature24462. Epub 2017 Nov 8.

5.

Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.

Basturk O, Berger MF, Yamaguchi H, Adsay V, Askan G, Bhanot UK, Zehir A, Carneiro F, Hong SM, Zamboni G, Dikoglu E, Jobanputra V, Wrzeszczynski KO, Balci S, Allen P, Ikari N, Takeuchi S, Akagawa H, Kanno A, Shimosegawa T, Morikawa T, Motoi F, Unno M, Higuchi R, Yamamoto M, Shimizu K, Furukawa T, Klimstra DS.

Mod Pathol. 2017 Dec;30(12):1760-1772. doi: 10.1038/modpathol.2017.60. Epub 2017 Aug 4.

6.

Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma.

Hsieh JJ, Chen D, Wang PI, Marker M, Redzematovic A, Chen YB, Selcuklu SD, Weinhold N, Bouvier N, Huberman KH, Bhanot U, Chevinsky MS, Patel P, Pinciroli P, Won HH, You D, Viale A, Lee W, Hakimi AA, Berger MF, Socci ND, Cheng EH, Knox J, Voss MH, Voi M, Motzer RJ.

Eur Urol. 2017 Mar;71(3):405-414. doi: 10.1016/j.eururo.2016.10.007. Epub 2016 Oct 15.

7.

The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes.

Basturk O, Tan M, Bhanot U, Allen P, Adsay V, Scott SN, Shah R, Berger MF, Askan G, Dikoglu E, Jobanputra V, Wrzeszczynski KO, Sigel C, Iacobuzio-Donahue C, Klimstra DS.

Mod Pathol. 2016 Sep;29(9):1058-69. doi: 10.1038/modpathol.2016.98. Epub 2016 Jun 10.

8.

Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.

Simon EP, Freije CA, Farber BA, Lalazar G, Darcy DG, Honeyman JN, Chiaroni-Clarke R, Dill BD, Molina H, Bhanot UK, La Quaglia MP, Rosenberg BR, Simon SM.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5916-25. doi: 10.1073/pnas.1424894112. Epub 2015 Oct 21.

9.

GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Tan MC, Basturk O, Brannon AR, Bhanot U, Scott SN, Bouvier N, LaFemina J, Jarnagin WR, Berger MF, Klimstra D, Allen PJ.

J Am Coll Surg. 2015 May;220(5):845-854.e1. doi: 10.1016/j.jamcollsurg.2014.11.029. Epub 2015 Feb 11.

10.

The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients.

Darcy DG, Chiaroni-Clarke R, Murphy JM, Honeyman JN, Bhanot U, LaQuaglia MP, Simon SM.

Oncotarget. 2015 Jan 20;6(2):755-70.

11.

Combined melanocytic and sweat gland neoplasm: cell subsets harbor an identical HRAS mutation in phacomatosis pigmentokeratotica.

Li JY, Berger MF, Marghoob A, Bhanot UK, Toyohara JP, Pulitzer MP.

J Cutan Pathol. 2014 Aug;41(8):663-71. doi: 10.1111/cup.12339. Epub 2014 Jul 9.

12.

Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma.

Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM.

Science. 2014 Feb 28;343(6174):1010-4. doi: 10.1126/science.1249484.

13.

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma.

Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK; NISC Comparative Sequencing Program, Chen G, Elnitski LL, Davies MA, Gershenwald JE, Carter H, Karchin R, Robinson W, Robinson S, Rosenberg SA, Collins FS, Parmigiani G, Komar AA, Kimchi-Sarfaty C, Hayward NK, Margulies EH, Samuels Y.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13481-6. doi: 10.1073/pnas.1304227110. Epub 2013 Jul 30. Erratum in: Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):563.

14.

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes.

Parker SC, Gartner J, Cardenas-Navia I, Wei X, Ozel Abaan H, Ajay SS, Hansen NF, Song L, Bhanot UK, Killian JK, Gindin Y, Walker RL, Meltzer PS, Mullikin JC, Furey TS, Crawford GE, Rosenberg SA, Samuels Y, Margulies EH.

PLoS Genet. 2012;8(8):e1002871. doi: 10.1371/journal.pgen.1002871. Epub 2012 Aug 9.

15.

In vivo evaluation of the chitosan-based haemostatic agent Omni-stat® in porcine liver resection and in liver injury.

Jegatheeswaran S, Bhanot U, Siriwardena AK.

Eur Surg Res. 2012;49(2):73-9. doi: 10.1159/000337867. Epub 2012 Aug 17.

PMID:
22906964
16.

PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression.

Kalinsky K, Heguy A, Bhanot UK, Patil S, Moynahan ME.

Breast Cancer Res Treat. 2011 Sep;129(2):635-43. doi: 10.1007/s10549-011-1601-4. Epub 2011 May 27.

PMID:
21617917
17.
18.

Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality.

Rudloff U, Bhanot U, Gerald W, Klimstra DS, Jarnagin WR, Brennan MF, Allen PJ.

Ann Surg Oncol. 2010 Aug;17(8):2229-36. doi: 10.1245/s10434-010-0959-6. Epub 2010 Feb 17.

19.

PIK3CA mutation associates with improved outcome in breast cancer.

Kalinsky K, Jacks LM, Heguy A, Patil S, Drobnjak M, Bhanot UK, Hedvat CV, Traina TA, Solit D, Gerald W, Moynahan ME.

Clin Cancer Res. 2009 Aug 15;15(16):5049-59. doi: 10.1158/1078-0432.CCR-09-0632. Epub 2009 Aug 11.

20.

NF-kappaB regulates androgen receptor expression and prostate cancer growth.

Zhang L, Altuwaijri S, Deng F, Chen L, Lal P, Bhanot UK, Korets R, Wenske S, Lilja HG, Chang C, Scher HI, Gerald WL.

Am J Pathol. 2009 Aug;175(2):489-99. doi: 10.2353/ajpath.2009.080727. Epub 2009 Jul 23.

21.

Mechanisms of parenchymal injury and signaling pathways in ectatic ducts of chronic pancreatitis: implications for pancreatic carcinogenesis.

Bhanot UK, Möller P.

Lab Invest. 2009 May;89(5):489-97. doi: 10.1038/labinvest.2009.19. Epub 2009 Mar 23. Review.

22.

Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.

Vogler M, Walczak H, Stadel D, Haas TL, Genze F, Jovanovic M, Bhanot U, Hasel C, Möller P, Gschwend JE, Simmet T, Debatin KM, Fulda S.

Cancer Res. 2009 Mar 15;69(6):2425-34. doi: 10.1158/0008-5472.CAN-08-2436. Epub 2009 Mar 3.

23.

Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia.

Bhanot UK.

Hepatobiliary Pancreat Dis Int. 2008 Feb;7(1):106-7. No abstract available.

PMID:
18234650
24.

Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.

Bhanot U, Köhntop R, Hasel C, Möller P.

J Pathol. 2008 Feb;214(3):312-9.

PMID:
18069660
25.

[Parenchymal regression in chronic pancreatitis spares islets reprogrammed for expression of NFkappaB and IAPs].

Hasel C, Bhanot UK, Maier R, Sträter J, Möller P.

Verh Dtsch Ges Pathol. 2006;90:159-67. German.

PMID:
17867593
26.

Fine needle aspiration cytology of metastatic skin nodules. A report of 2 cases.

Bhanot UK, Rauniyar SK, Mital VP.

Acta Cytol. 2007 Jan-Feb;51(1):95-8.

PMID:
17328506
27.

Dichotomy of fates of pancreatic epithelia in chronic pancreatitis: apoptosis versus survival.

Bhanot UK, Möller P, Hasel C.

Trends Mol Med. 2006 Aug;12(8):351-7. Epub 2006 Jul 7.

PMID:
16828345
28.
29.

Atypical squamous cells: ASCUS is out! Now, ASC-US and ASC-H for reporting of cervical cytology.

Bhanot UK.

Asian Pac J Cancer Prev. 2006 Jan-Mar;7(1):161-2. No abstract available.

30.

Parenchymal regression in chronic pancreatitis spares islets reprogrammed for the expression of NFkappaB and IAPs.

Hasel C, Bhanot UK, Heydrich R, Sträter J, Möller P.

Lab Invest. 2005 Oct;85(10):1263-75.

32.

Pathologically elevated cyclic hydrostatic pressure induces CD95-mediated apoptotic cell death in vascular endothelial cells.

Hasel C, Dürr S, Bauer A, Heydrich R, Brüderlein S, Tambi T, Bhanot U, Möller P.

Am J Physiol Cell Physiol. 2005 Aug;289(2):C312-22. Epub 2005 Mar 16.

33.

Primary spinal paraganglioma--a case report.

Garbyal RS, Agarwal A, Bhanot U, Rauniyar SK, Mital VP.

Indian J Pathol Microbiol. 2003 Jul;46(3):490-1. Review. No abstract available.

PMID:
15025320
34.

Correlation of H. pylori density with grading of chronic gastritis.

Choudhary CK, Bhanot UK, Agarwal A, Garbyal RS.

Indian J Pathol Microbiol. 2001 Jul;44(3):325-8.

PMID:
12024923

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