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Items: 30

1.

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers.

Nakada EM, Bhakta NR, Korwin-Mihavics BR, Kumar A, Chamberlain N, Bruno SR, Chapman DG, Hoffman SM, Daphtary N, Aliyeva M, Irvin CG, Dixon AE, Woodruff PG, Amin S, Poynter ME, Desai DH, Anathy V.

JCI Insight. 2019 May 2;4(9). pii: 98101. doi: 10.1172/jci.insight.98101. eCollection 2019 May 2.

2.

The Peak Index: Spirometry Metric for Airflow Obstruction Severity and Heterogeneity.

Bhatt SP, Bodduluri S, Raghav V, Bhakta NR, Wilson CG, Kim YI, Eberlein M, Sciurba FC, Han MK, Dransfield MT, Nakhmani A.

Ann Am Thorac Soc. 2019 Aug;16(8):982-989. doi: 10.1513/AnnalsATS.201811-812OC.

PMID:
30865842
3.

New Spirometry Indices for Detecting Mild Airflow Obstruction.

Bhatt SP, Bhakta NR, Wilson CG, Cooper CB, Barjaktarevic I, Bodduluri S, Kim YI, Eberlein M, Woodruff PG, Sciurba FC, Castaldi PJ, Han MK, Dransfield MT, Nakhmani A.

Sci Rep. 2018 Nov 30;8(1):17484. doi: 10.1038/s41598-018-35930-2.

4.

Large Differences in Small RNA Composition Between Human Biofluids.

Godoy PM, Bhakta NR, Barczak AJ, Cakmak H, Fisher S, MacKenzie TC, Patel T, Price RW, Smith JF, Woodruff PG, Erle DJ.

Cell Rep. 2018 Oct 30;25(5):1346-1358. doi: 10.1016/j.celrep.2018.10.014.

5.

IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.

Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC.

6.

Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia.

Lachowicz-Scroggins ME, Finkbeiner WE, Gordon ED, Yuan S, Zlock L, Bhakta NR, Woodruff PG, Fahy JV, Boushey HA.

Clin Exp Allergy. 2017 Dec;47(12):1534-1545. doi: 10.1111/cea.13015. Epub 2017 Sep 26.

PMID:
28833774
7.

Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.

8.

By Expanding the Color Palette, CO-Oximetry Overcomes Some, but Not All, of the Uncommon Limitations of Pulse Oximetry.

Bhakta NR.

Ann Am Thorac Soc. 2017 Apr;14(4):609. doi: 10.1513/AnnalsATS.201611-921LE. No abstract available.

PMID:
28362526
9.

Insights from Recognition of a Contradiction in the Equations that Define the Diffusing Capacity of the Lung for Carbon Monoxide.

Bhakta NR.

Ann Am Thorac Soc. 2017 Mar;14(3):473-474. doi: 10.1513/AnnalsATS.201611-920LE. No abstract available.

PMID:
28248579
10.

Grease fires turn up the heat in autoimmune disease.

Bhakta NR.

Sci Transl Med. 2017 Jan 25;9(374). pii: eaal4997. doi: 10.1126/scitranslmed.aal4997.

PMID:
28123070
11.

Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.

Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E; Severe Asthma Research Program.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1439-1448. doi: 10.1164/rccm.201607-1453OC. Erratum in: Am J Respir Crit Care Med. 2018 Apr 1;197(7):970-971.

12.

Pitfalls of probiotics.

Bhakta NR.

Sci Transl Med. 2016 Dec 7;8(368):368ec194. No abstract available.

PMID:
27928020
13.

Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.

Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ; National Heart, Lung and Blood Institute's “AsthmaNet”.

J Allergy Clin Immunol. 2017 Jul;140(1):63-75. doi: 10.1016/j.jaci.2016.08.055. Epub 2016 Nov 10.

14.

Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.

Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313. doi: 10.1164/rccm.201602-0419OC. Erratum in: Am J Respir Crit Care Med. 2018 Apr 1;197(7):971.

15.

IFN-γ-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells.

Ramstein J, Broos CE, Simpson LJ, Ansel KM, Sun SA, Ho ME, Woodruff PG, Bhakta NR, Christian L, Nguyen CP, Antalek BJ, Benn BS, Hendriks RW, van den Blink B, Kool M, Koth LL.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1281-91. doi: 10.1164/rccm.201507-1499OC.

16.

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z.

Nature. 2015 Oct 1;526(7571):131-5. doi: 10.1038/nature15260. Epub 2015 Sep 23.

17.

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM.

Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2.

18.

IL-17 and "TH2-high" asthma: Adding fuel to the fire?

Bhakta NR, Erle DJ.

J Allergy Clin Immunol. 2014 Nov;134(5):1187-8. doi: 10.1016/j.jaci.2014.07.034. Epub 2014 Aug 28. No abstract available.

PMID:
25174869
19.

Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes.

Su R, Li MM, Bhakta NR, Solberg OD, Darnell EP, Ramstein J, Garudadri S, Ho M, Woodruff PG, Koth LL.

Eur Respir J. 2014 Oct;44(4):985-93. doi: 10.1183/09031936.00039714. Epub 2014 Aug 19.

20.

Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma.

Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS.

PLoS One. 2014 Jun 10;9(6):e99084. doi: 10.1371/journal.pone.0099084. eCollection 2014.

21.

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.

Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV.

J Allergy Clin Immunol. 2014 Feb;133(2):388-94. doi: 10.1016/j.jaci.2013.07.036. Epub 2013 Sep 24.

22.

A qPCR-based metric of Th2 airway inflammation in asthma.

Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG.

Clin Transl Allergy. 2013 Jul 17;3(1):24. doi: 10.1186/2045-7022-3-24.

23.

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients.

Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff PG, Erle DJ, Wheelock ÅM.

J Allergy Clin Immunol. 2013 Mar;131(3):894-903. doi: 10.1016/j.jaci.2012.11.039. Epub 2013 Jan 16.

24.

Airway epithelial miRNA expression is altered in asthma.

Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG.

Am J Respir Crit Care Med. 2012 Nov 15;186(10):965-74. doi: 10.1164/rccm.201201-0027OC. Epub 2012 Sep 6.

25.

Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis.

Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff PG.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1153-63. doi: 10.1164/rccm.201106-1143OC. Epub 2011 Aug 18.

26.

Human asthma phenotypes: from the clinic, to cytokines, and back again.

Bhakta NR, Woodruff PG.

Immunol Rev. 2011 Jul;242(1):220-32. doi: 10.1111/j.1600-065X.2011.01032.x. Review.

27.

Real-time measurement of signaling and motility during T cell development in the thymus.

Bhakta NR, Lewis RS.

Semin Immunol. 2005 Dec;17(6):411-20. Epub 2005 Oct 25. Review.

PMID:
16256363
28.

Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment.

Bhakta NR, Oh DY, Lewis RS.

Nat Immunol. 2005 Feb;6(2):143-51. Epub 2005 Jan 16.

PMID:
15654342
29.

Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy.

Bousso P, Bhakta NR, Lewis RS, Robey E.

Science. 2002 Jun 7;296(5574):1876-80.

30.

The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins.

Bhakta NR, Garcia AM, Frank EH, Grodzinsky AJ, Morales TI.

J Biol Chem. 2000 Feb 25;275(8):5860-6.

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