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Items: 1 to 50 of 314

1.

Easy Employment and Crosstalk-Free Detection of Seven Fluorophores in a Widefield Fluorescence Microscope.

Bhakdi SC, Thaicharoen P.

Methods Protoc. 2018 Jun 1;1(2). pii: E20. doi: 10.3390/mps1020020.

2.

ADAM10 sheddase activation is controlled by cell membrane asymmetry.

Bleibaum F, Sommer A, Veit M, Rabe B, Andrä J, Kunzelmann K, Nehls C, Correa W, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K.

J Mol Cell Biol. 2019 Feb 12. doi: 10.1093/jmcb/mjz008. [Epub ahead of print]

PMID:
30753537
3.

Anoctamin-6 regulates ADAM sheddase function.

Veit M, Koyro KI, Ahrens B, Bleibaum F, Munz M, Rövekamp H, Andrä J, Schreiber R, Kunzelmann K, Sommer A, Bhakdi S, Reiss K.

Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt A):1598-1610. doi: 10.1016/j.bbamcr.2018.08.011. Epub 2018 Aug 23.

PMID:
30327201
4.

Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding.

Sommer A, Düppe M, Baumecker L, Kordowski F, Büch J, Chico JF, Fritsch J, Schütze S, Adam D, Sperrhacke M, Bhakdi S, Reiss K.

Oncotarget. 2017 Aug 7;8(42):72584-72596. doi: 10.18632/oncotarget.19983. eCollection 2017 Sep 22.

5.

The plasma membrane: Penultimate regulator of ADAM sheddase function.

Reiss K, Bhakdi S.

Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2082-2087. doi: 10.1016/j.bbamcr.2017.06.006. Epub 2017 Jun 15. Review.

6.

How membrane asymmetry regulates ADAM17 sheddase function.

Sommer A, Bhakdi S, Reiss K.

Cell Cycle. 2016 Nov 16;15(22):2995-2996. Epub 2016 Jul 27. No abstract available.

7.

Phosphatidylserine exposure is required for ADAM17 sheddase function.

Sommer A, Kordowski F, Büch J, Maretzky T, Evers A, Andrä J, Düsterhöft S, Michalek M, Lorenzen I, Somasundaram P, Tholey A, Sönnichsen FD, Kunzelmann K, Heinbockel L, Nehls C, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K.

Nat Commun. 2016 May 10;7:11523. doi: 10.1038/ncomms11523.

8.

Malarial anemia: digestive vacuole of Plasmodium falciparum mediates complement deposition on bystander cells to provoke hemophagocytosis.

Dasari P, Fries A, Heber SD, Salama A, Blau IW, Lingelbach K, Bhakdi SC, Udomsangpetch R, Torzewski M, Reiss K, Bhakdi S.

Med Microbiol Immunol. 2014 Dec;203(6):383-93. doi: 10.1007/s00430-014-0347-0. Epub 2014 Jul 2.

PMID:
24985035
9.

Antibody-conjugated paramagnetic nanobeads: kinetics of bead-cell binding.

Waseem S, Allen MA, Schreier S, Udomsangpetch R, Bhakdi SC.

Int J Mol Sci. 2014 May 19;15(5):8821-34. doi: 10.3390/ijms15058821.

10.

Proteomic profiling of secreted proteins for the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells.

Bal G, Kamhieh-Milz J, Sterzer V, Al-Samman M, Debski J, Klein O, Kamhieh-Milz S, Bhakdi S, Salama A.

Cell Transplant. 2013;22(7):1185-99. doi: 10.3727/096368912X657288. Epub 2012 Oct 1.

PMID:
23031318
11.

Complement and atherosclerosis-united to the point of no return?

Torzewski M, Bhakdi S.

Clin Biochem. 2013 Jan;46(1-2):20-5. doi: 10.1016/j.clinbiochem.2012.09.012. Epub 2012 Sep 23. Review.

PMID:
23010447
12.

Mechanisms of invasion and persistence of infectious agents.

Bhakdi S.

Med Microbiol Immunol. 2012 Nov;201(4):407. doi: 10.1007/s00430-012-0275-9. Epub 2012 Sep 23. No abstract available.

PMID:
23001362
13.

Pore-forming bacterial toxins and antimicrobial peptides as modulators of ADAM function.

Reiss K, Bhakdi S.

Med Microbiol Immunol. 2012 Nov;201(4):419-26. doi: 10.1007/s00430-012-0260-3. Epub 2012 Sep 13. Review.

PMID:
22972233
14.

Pathogenesis of malaria revisited.

Dasari P, Bhakdi S.

Med Microbiol Immunol. 2012 Nov;201(4):599-604. doi: 10.1007/s00430-012-0265-y. Epub 2012 Sep 7. Review.

PMID:
22955244
15.

Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation.

Sommer A, Fries A, Cornelsen I, Speck N, Koch-Nolte F, Gimpl G, Andrä J, Bhakdi S, Reiss K.

J Biol Chem. 2012 Jul 6;287(28):23678-89. doi: 10.1074/jbc.M112.362756. Epub 2012 May 21.

16.

Use of quantitative microbiological analyses to trace origin of contamination of parenteral nutrition solutions.

Bhakdi S, Krämer I, Siegel E, Jansen B, Exner M.

Med Microbiol Immunol. 2012 May;201(2):231-7. doi: 10.1007/s00430-012-0236-3. Epub 2012 Apr 7.

PMID:
22484833
17.

Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation.

Dasari P, Heber SD, Beisele M, Torzewski M, Reifenberg K, Orning C, Fries A, Zapf AL, Baumeister S, Lingelbach K, Udomsangpetch R, Bhakdi SC, Reiss K, Bhakdi S.

Blood. 2012 May 3;119(18):4301-10. doi: 10.1182/blood-2011-11-392134. Epub 2012 Mar 8.

18.

Digestive vacuoles of Plasmodium falciparum are selectively phagocytosed by and impair killing function of polymorphonuclear leukocytes.

Dasari P, Reiss K, Lingelbach K, Baumeister S, Lucius R, Udomsangpetch R, Bhakdi SC, Bhakdi S.

Blood. 2011 Nov 3;118(18):4946-56. doi: 10.1182/blood-2011-05-353920. Epub 2011 Sep 12.

19.

Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity.

Reiss K, Cornelsen I, Husmann M, Gimpl G, Bhakdi S.

J Biol Chem. 2011 Jul 29;286(30):26931-42. doi: 10.1074/jbc.M111.243485. Epub 2011 Jun 3.

20.

Optimized high gradient magnetic separation for isolation of Plasmodium-infected red blood cells.

Bhakdi SC, Ottinger A, Somsri S, Sratongno P, Pannadaporn P, Chimma P, Malasit P, Pattanapanyasat K, Neumann HP.

Malar J. 2010 Feb 2;9:38. doi: 10.1186/1475-2875-9-38.

21.

Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.

Koike T, Kitajima S, Yu Y, Nishijima K, Zhang J, Ozaki Y, Morimoto M, Watanabe T, Bhakdi S, Asada Y, Chen YE, Fan J.

Circulation. 2009 Nov 24;120(21):2088-94. doi: 10.1161/CIRCULATIONAHA.109.872796. Epub 2009 Nov 9.

22.

Possible hidden hazards of mass vaccination against new influenza A/H1N1: have the cardiovascular risks been adequately weighed?

Bhakdi S, Lackner K, Doerr HW.

Med Microbiol Immunol. 2009 Nov;198(4):205-9. doi: 10.1007/s00430-009-0130-9.

PMID:
19851782
23.

Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium.

Kloft N, Busch T, Neukirch C, Weis S, Boukhallouk F, Bobkiewicz W, Cibis I, Bhakdi S, Husmann M.

Biochem Biophys Res Commun. 2009 Aug 7;385(4):503-6. doi: 10.1016/j.bbrc.2009.05.121. Epub 2009 Jun 2.

PMID:
19497299
24.

Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein.

Lux CA, Koschinski A, Dersch K, Husmann M, Bhakdi S.

Atherosclerosis. 2009 Nov;207(1):116-22. doi: 10.1016/j.atherosclerosis.2009.04.004. Epub 2009 Apr 11.

PMID:
19423111
25.

Pore formation by Vibrio cholerae cytolysin follows the same archetypical mode as beta-barrel toxins from gram-positive organisms.

Löhner S, Walev I, Boukhallouk F, Palmer M, Bhakdi S, Valeva A.

FASEB J. 2009 Aug;23(8):2521-8. doi: 10.1096/fj.08-127688. Epub 2009 Mar 10.

PMID:
19276173
26.

Investigation of Sudan IV staining areas in aortas of infants and children: possible prelesional stages of atherogenesis.

Torzewski M, Navarro B, Cheng F, Canisius A, Schmidt T, Bhakdi S, Urban R, Lackner KJ.

Atherosclerosis. 2009 Sep;206(1):159-67. doi: 10.1016/j.atherosclerosis.2009.01.038. Epub 2009 Feb 7.

PMID:
19268943
27.

Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells.

Fenske D, Dersch K, Lux C, Zipse L, Suriyaphol P, Dragneva Y, Han SR, Bhakdi S, Husmann M.

Thromb Haemost. 2008 Dec;100(6):1146-54.

PMID:
19132242
28.

Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis.

Husmann M, Beckmann E, Boller K, Kloft N, Tenzer S, Bobkiewicz W, Neukirch C, Bayley H, Bhakdi S.

FEBS Lett. 2009 Jan 22;583(2):337-44. doi: 10.1016/j.febslet.2008.12.028. Epub 2008 Dec 25.

29.

Putative identification of an amphipathic alpha-helical sequence in hemolysin of Escherichia coli (HlyA) involved in transmembrane pore formation.

Valeva A, Siegel I, Wylenzek M, Wassenaar TM, Weis S, Heinz N, Schmitt R, Fischer C, Reinartz R, Bhakdi S, Walev I.

Biol Chem. 2008 Sep;389(9):1201-7. doi: 10.1515/BC.2008.136.

PMID:
18713007
30.

Endotoxin accelerates atherosclerosis independent of complement activation.

Reifenberg K, Lehr HA, Fan J, Koike T, Wiese E, Küpper I, Sagban TA, Schaefer SC, Zähringer U, Torzewski M, Lackner KJ, Bhakdi S.

Thromb Res. 2009 Feb;123(4):653-8. doi: 10.1016/j.thromres.2008.06.017. Epub 2008 Aug 9. No abstract available.

PMID:
18692867
31.

Mast cells determine the magnitude of bacterial toxin-induced skin inflammation.

Metz M, Magerl M, Kühl NF, Valeva A, Bhakdi S, Maurer M.

Exp Dermatol. 2009 Feb;18(2):160-6. doi: 10.1111/j.1600-0625.2008.00778.x. Epub 2008 Jul 17.

PMID:
18643847
32.

Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity.

Schwarz M, Spath L, Lux CA, Paprotka K, Torzewski M, Dersch K, Koch-Brandt C, Husmann M, Bhakdi S.

Thromb Haemost. 2008 Jul;100(1):110-8. doi: 10.1160/TH07-12-0737.

PMID:
18612545
33.

No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice.

Torzewski M, Reifenberg K, Cheng F, Wiese E, Küpper I, Crain J, Lackner KJ, Bhakdi S.

Thromb Haemost. 2008 Jan;99(1):196-201. doi: 10.1160/TH07-10-0595.

PMID:
18217154
34.

Pro-inflammatory feedback activation cycle evoked by attack of Vibrio cholerae cytolysin on human neutrophil granulocytes.

Valeva A, Walev I, Weis S, Boukhallouk F, Wassenaar TM, Bhakdi S.

Med Microbiol Immunol. 2008 Sep;197(3):285-93. Epub 2007 Sep 20.

PMID:
17882454
35.

Characterization of a catalase-negative methicillin-resistant Staphylococcus aureus strain.

Grüner BM, Han SR, Meyer HG, Wulf U, Bhakdi S, Siegel EK.

J Clin Microbiol. 2007 Aug;45(8):2684-5. Epub 2007 Jun 20.

36.

Re-evaluating acridine orange for rapid flow cytometric enumeration of parasitemia in malaria-infected rodents.

Bhakdi SC, Sratongno P, Chimma P, Rungruang T, Chuncharunee A, Neumann HP, Malasit P, Pattanapanyasat K.

Cytometry A. 2007 Sep;71(9):662-7.

37.

[Immunopathogenesis of atherosclerosis: the Mainz hypothesis].

Bhakdi S.

Med Monatsschr Pharm. 2006 Oct;29(10):356-9. Review. German.

PMID:
17058894
38.

Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferation.

Haugwitz U, Bobkiewicz W, Han SR, Beckmann E, Veerachato G, Shaid S, Biehl S, Dersch K, Bhakdi S, Husmann M.

Cell Microbiol. 2006 Oct;8(10):1591-600.

PMID:
16984414
39.

Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore.

Valeva A, Hellmann N, Walev I, Strand D, Plate M, Boukhallouk F, Brack A, Hanada K, Decker H, Bhakdi S.

J Biol Chem. 2006 Sep 8;281(36):26014-21. Epub 2006 Jul 9.

40.

Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.

Petry F, Torzewski M, Bohl J, Wilhelm-Schwenkmezger T, Scheid P, Walochnik J, Michel R, Zöller L, Werhahn KJ, Bhakdi S, Lackner KJ.

J Clin Microbiol. 2006 May;44(5):1903-4.

41.

Differential role of p38 mitogen activated protein kinase for cellular recovery from attack by pore-forming S. aureus alpha-toxin or streptolysin O.

Husmann M, Dersch K, Bobkiewicz W, Beckmann E, Veerachato G, Bhakdi S.

Biochem Biophys Res Commun. 2006 Jun 16;344(4):1128-34. Epub 2006 Apr 21.

PMID:
16643845
42.

Why Escherichia coli alpha-hemolysin induces calcium oscillations in mammalian cells--the pore is on its own.

Koschinski A, Repp H, Unver B, Dreyer F, Brockmeier D, Valeva A, Bhakdi S, Walev I.

FASEB J. 2006 May;20(7):973-5. Epub 2006 Apr 5.

PMID:
16597673
43.

Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement.

Avirutnan P, Punyadee N, Noisakran S, Komoltri C, Thiemmeca S, Auethavornanan K, Jairungsri A, Kanlaya R, Tangthawornchaikul N, Puttikhunt C, Pattanakitsakul SN, Yenchitsomanus PT, Mongkolsapaya J, Kasinrerk W, Sittisombut N, Husmann M, Blettner M, Vasanawathana S, Bhakdi S, Malasit P.

J Infect Dis. 2006 Apr 15;193(8):1078-88. Epub 2006 Mar 9.

PMID:
16544248
44.

Staphylococcus aureus bicomponent gamma-hemolysins, HlgA, HlgB, and HlgC, can form mixed pores containing all components.

Dalla Serra M, Coraiola M, Viero G, Comai M, Potrich C, Ferreras M, Baba-Moussa L, Colin DA, Menestrina G, Bhakdi S, Prévost G.

J Chem Inf Model. 2005 Nov-Dec;45(6):1539-45.

PMID:
16309251
45.

Binding of Escherichia coli hemolysin and activation of the target cells is not receptor-dependent.

Valeva A, Walev I, Kemmer H, Weis S, Siegel I, Boukhallouk F, Wassenaar TM, Chavakis T, Bhakdi S.

J Biol Chem. 2005 Nov 4;280(44):36657-63. Epub 2005 Aug 30.

46.

Identification of the membrane penetrating domain of Vibrio cholerae cytolysin as a beta-barrel structure.

Valeva A, Walev I, Boukhallouk F, Wassenaar TM, Heinz N, Hedderich J, Lautwein S, Möcking M, Weis S, Zitzer A, Bhakdi S.

Mol Microbiol. 2005 Jul;57(1):124-31.

47.

Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?

Reifenberg K, Lehr HA, Baskal D, Wiese E, Schaefer SC, Black S, Samols D, Torzewski M, Lackner KJ, Husmann M, Blettner M, Bhakdi S.

Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1641-6. Epub 2005 May 26.

PMID:
15920030
48.

Fatty acids liberated from low-density lipoprotein trigger endothelial apoptosis via mitogen-activated protein kinases.

Dersch K, Ichijo H, Bhakdi S, Husmann M.

Cell Death Differ. 2005 Aug;12(8):1107-14.

49.

Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis.

Torzewski M, Suriyaphol P, Paprotka K, Spath L, Ochsenhirt V, Schmitt A, Han SR, Husmann M, Gerl VB, Bhakdi S, Lackner KJ.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2130-6. Epub 2004 Sep 2.

PMID:
15345515
50.

A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin.

Valeva A, Walev I, Weis S, Boukhallouk F, Wassenaar TM, Endres K, Fahrenholz F, Bhakdi S, Zitzer A.

J Biol Chem. 2004 Jun 11;279(24):25143-8. Epub 2004 Apr 5.

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