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Items: 12


Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites.

Madison BJ, Clark KA, Bhachech N, Hollenhorst PC, Graves BJ, Currie SL.

J Biol Chem. 2018 Nov 30;293(48):18624-18635. doi: 10.1074/jbc.RA118.003352. Epub 2018 Oct 12.


ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.

Currie SL, Doane JJ, Evans KS, Bhachech N, Madison BJ, Lau DKW, McIntosh LP, Skalicky JJ, Clark KA, Graves BJ.

J Mol Biol. 2017 Oct 13;429(20):2975-2995. doi: 10.1016/j.jmb.2017.06.024. Epub 2017 Jul 17.


Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085. Epub 2015 Oct 8.


Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor.

Desjardins G, Meeker CA, Bhachech N, Currie SL, Okon M, Graves BJ, McIntosh LP.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11019-24. doi: 10.1073/pnas.1401891111. Epub 2014 Jul 14.


Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6.

De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP.

J Mol Biol. 2014 Apr 3;426(7):1390-406. doi: 10.1016/j.jmb.2013.11.031. Epub 2013 Dec 12.


Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain.

Coyne HJ 3rd, De S, Okon M, Green SM, Bhachech N, Graves BJ, McIntosh LP.

J Mol Biol. 2012 Aug 3;421(1):67-84. doi: 10.1016/j.jmb.2012.05.010. Epub 2012 May 12.


Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli isolates producing TEM-10 and TEM-43 beta-lactamases from St. Louis, Missouri.

Yang Y, Bhachech N, Bradford PA, Jett BD, Sahm DF, Bush K.

Antimicrob Agents Chemother. 1998 Jul;42(7):1671-6.


TEM-28 from an Escherichia coli clinical isolate is a member of the His-164 family of TEM-1 extended-spectrum beta-lactamases.

Bradford PA, Jacobus NV, Bhachech N, Bush K.

Antimicrob Agents Chemother. 1996 Jan;40(1):260-2.


Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

Wei SJ, Chang RL, Wong CQ, Bhachech N, Cui XX, Hennig E, Yagi H, Sayer JM, Jerina DM, Preston BD, et al.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11227-30.

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