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Items: 21

1.

Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain.

Niekamp S, Coudray N, Zhang N, Vale RD, Bhabha G.

EMBO J. 2019 Jul 1;38(13):e101414. doi: 10.15252/embj.2018101414. Epub 2019 May 31.

2.

Nanometer-accuracy distance measurements between fluorophores at the single-molecule level.

Niekamp S, Sung J, Huynh W, Bhabha G, Vale RD, Stuurman N.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4275-4284. doi: 10.1073/pnas.1815826116. Epub 2019 Feb 15.

3.

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.

Ekiert DC, Bhabha G, Isom GL, Greenan G, Ovchinnikov S, Henderson IR, Cox JS, Vale RD.

Cell. 2017 Apr 6;169(2):273-285.e17. doi: 10.1016/j.cell.2017.03.019.

4.

How Dynein Moves Along Microtubules.

Bhabha G, Johnson GT, Schroeder CM, Vale RD.

Trends Biochem Sci. 2016 Jan;41(1):94-105. doi: 10.1016/j.tibs.2015.11.004. Epub 2015 Dec 9. Review.

5.

Exploring the repeat protein universe through computational protein design.

Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D.

Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16.

6.

Keep on moving: discovering and perturbing the conformational dynamics of enzymes.

Bhabha G, Biel JT, Fraser JS.

Acc Chem Res. 2015 Feb 17;48(2):423-30. doi: 10.1021/ar5003158. Epub 2014 Dec 24. Review.

7.

Allosteric communication in the dynein motor domain.

Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD.

Cell. 2014 Nov 6;159(4):857-68. doi: 10.1016/j.cell.2014.10.018.

8.

De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.

Liu Y, Zhang X, Tan YL, Bhabha G, Ekiert DC, Kipnis Y, Bjelic S, Baker D, Kelly JW.

J Am Chem Soc. 2014 Sep 24;136(38):13102-5. doi: 10.1021/ja5056356. Epub 2014 Sep 11.

9.

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes.

McKenney RJ, Huynh W, Tanenbaum ME, Bhabha G, Vale RD.

Science. 2014 Jul 18;345(6194):337-41. doi: 10.1126/science.1254198. Epub 2014 Jun 19.

10.

Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.

Liu Y, Tan YL, Zhang X, Bhabha G, Ekiert DC, Genereux JC, Cho Y, Kipnis Y, Bjelic S, Baker D, Kelly JW.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4449-54. doi: 10.1073/pnas.1323268111. Epub 2014 Mar 3.

11.

A common solution to group 2 influenza virus neutralization.

Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):445-50. doi: 10.1073/pnas.1319058110. Epub 2013 Dec 11.

12.

Divergent evolution of protein conformational dynamics in dihydrofolate reductase.

Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE.

Nat Struct Mol Biol. 2013 Nov;20(11):1243-9. doi: 10.1038/nsmb.2676. Epub 2013 Sep 29.

13.

Automated identification of functional dynamic contact networks from X-ray crystallography.

van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS.

Nat Methods. 2013 Sep;10(9):896-902. doi: 10.1038/nmeth.2592. Epub 2013 Aug 4.

14.

Cross-neutralization of influenza A viruses mediated by a single antibody loop.

Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA.

Nature. 2012 Sep 27;489(7417):526-32. doi: 10.1038/nature11414. Epub 2012 Sep 16.

15.

Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR.

Bhabha G, Tuttle L, Martinez-Yamout MA, Wright PE.

FEBS Lett. 2011 Nov 16;585(22):3528-32. doi: 10.1016/j.febslet.2011.10.014. Epub 2011 Oct 20.

16.

A highly conserved neutralizing epitope on group 2 influenza A viruses.

Ekiert DC, Friesen RH, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJ, Brandenburg B, Vogels R, Brakenhoff JP, Kompier R, Koldijk MH, Cornelissen LA, Poon LL, Peiris M, Koudstaal W, Wilson IA, Goudsmit J.

Science. 2011 Aug 12;333(6044):843-50. doi: 10.1126/science.1204839. Epub 2011 Jul 7.

17.

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE.

Science. 2011 Apr 8;332(6026):234-8. doi: 10.1126/science.1198542.

18.

Evaluating beta-turn mimics as beta-sheet folding nucleators.

Fuller AA, Du D, Liu F, Davoren JE, Bhabha G, Kroon G, Case DA, Dyson HJ, Powers ET, Wipf P, Gruebele M, Kelly JW.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11067-72. doi: 10.1073/pnas.0813012106. Epub 2009 Jun 18.

19.

Antibody recognition of a highly conserved influenza virus epitope.

Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA.

Science. 2009 Apr 10;324(5924):246-51. doi: 10.1126/science.1171491. Epub 2009 Feb 26.

20.

Structure discrimination for the C-terminal domain of Escherichia coli trigger factor in solution.

Yao Y, Bhabha G, Kroon G, Landes M, Dyson HJ.

J Biomol NMR. 2008 Jan;40(1):23-30. Epub 2007 Nov 28.

PMID:
18043871
21.

Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants.

Allikian MJ, Bhabha G, Dospoy P, Heydemann A, Ryder P, Earley JU, Wolf MJ, Rockman HA, McNally EM.

Hum Mol Genet. 2007 Dec 1;16(23):2933-43. Epub 2007 Sep 12.

PMID:
17855453

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