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Items: 11


Genome-Wide siRNA Screening Using Forward Transfection: Identification of Modulators of Membrane Trafficking in Mammalian Cells.

Bexiga MG, Simpson JC.

Methods Mol Biol. 2016;1470:39-48. doi: 10.1007/978-1-4939-6337-9_4.


A systematic High-Content Screening microscopy approach reveals key roles for Rab33b, OATL1 and Myo6 in nanoparticle trafficking in HeLa cells.

Panarella A, Bexiga MG, Galea G, O' Neill ED, Salvati A, Dawson KA, Simpson JC.

Sci Rep. 2016 Jul 4;6:28865. doi: 10.1038/srep28865.


A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking.

Galea G, Bexiga MG, Panarella A, O'Neill ED, Simpson JC.

J Cell Sci. 2015 Jul 1;128(13):2339-49. doi: 10.1242/jcs.167973. Epub 2015 May 21.


RNAi-mediated inhibition of apoptosis fails to prevent cationic nanoparticle-induced cell death in cultured cells.

Bexiga MG, Kelly C, Dawson KA, Simpson JC.

Nanomedicine (Lond). 2014 Aug;9(11):1651-64. doi: 10.2217/nnm.13.151. Epub 2013 Dec 20.


Time resolved study of cell death mechanisms induced by amine-modified polystyrene nanoparticles.

Wang F, Bexiga MG, Anguissola S, Boya P, Simpson JC, Salvati A, Dawson KA.

Nanoscale. 2013 Nov 21;5(22):10868-76. doi: 10.1039/c3nr03249c. Epub 2013 Oct 9.


Human diseases associated with form and function of the Golgi complex.

Bexiga MG, Simpson JC.

Int J Mol Sci. 2013 Sep 10;14(9):18670-81. doi: 10.3390/ijms140918670. Review.


Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death.

Yi P, Higa A, Taouji S, Bexiga MG, Marza E, Arma D, Castain C, Le Bail B, Simpson JC, Rosenbaum J, Balabaud C, Bioulac-Sage P, Blanc JF, Chevet E.

Mol Cancer Ther. 2012 Dec;11(12):2610-20. doi: 10.1158/1535-7163.MCT-12-0516. Epub 2012 Oct 5.


Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells.

Varela JA, Bexiga MG, Åberg C, Simpson JC, Dawson KA.

J Nanobiotechnology. 2012 Sep 24;10:39. doi: 10.1186/1477-3155-10-39.


Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R.

Nat Cell Biol. 2012 Jun 3;14(7):764-74. doi: 10.1038/ncb2510.


Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line.

Bexiga MG, Varela JA, Wang F, Fenaroli F, Salvati A, Lynch I, Simpson JC, Dawson KA.

Nanotoxicology. 2011 Dec;5(4):557-67. doi: 10.3109/17435390.2010.539713. Epub 2010 Dec 15.


Lymphocyte migration through the blood-brain barrier (BBB) in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and tumour necrosis factor (TNF)-alpha within the central nervous system (CNS): studies using an in vitro feline BBB model.

Fletcher NF, Bexiga MG, Brayden DJ, Brankin B, Willett BJ, Hosie MJ, Jacque JM, Callanan JJ.

Neuropathol Appl Neurobiol. 2009 Dec;35(6):592-602. doi: 10.1111/j.1365-2990.2009.01031.x. Epub 2009 May 26.


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