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Research Lifecycle to Increase the Substantial Real-world Impact of Research: Accelerating Innovations to Application.

Kilbourne AM, Braganza MZ, Bowersox NW, Goodrich DE, Miake-Lye I, Floyd N, Garrido MM, Frakt AB, Bever CT Jr, Vega R, Ramoni R.

Med Care. 2019 Oct;57 Suppl 10 Suppl 3:S206-S212. doi: 10.1097/MLR.0000000000001146.


Robot-Assisted Arm Training in Chronic Stroke: Addition of Transition-to-Task Practice.

Conroy SS, Wittenberg GF, Krebs HI, Zhan M, Bever CT, Whitall J.

Neurorehabil Neural Repair. 2019 Sep;33(9):751-761. doi: 10.1177/1545968319862558. Epub 2019 Jul 22.


A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions.

Makar T, Nimmagadda VK, Guda PR, Hampton B, Huang W, Kane MA, Fishman PS, Pessac B, Bever CT Jr, Trisler D.

Stem Cell Res Ther. 2018 May 2;9(1):127. doi: 10.1186/s13287-018-0858-5.


A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Short- and medium-term benefits.

Hugos CL, Chen Z, Chen Y, Turner AP, Haselkorn J, Chiara T, McCoy S, Bever CT Jr, Cameron MH, Bourdette D; VA MS Fatigue Study Group.

Mult Scler. 2019 Feb;25(2):275-285. doi: 10.1177/1352458517745723. Epub 2017 Dec 11.


Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis.

Gerzanich V, Makar TK, Guda PR, Kwon MS, Stokum JA, Woo SK, Ivanova S, Ivanov A, Mehta RI, Morris AB, Bryan J, Bever CT, Simard JM.

J Neuroinflammation. 2017 Sep 2;14(1):177. doi: 10.1186/s12974-017-0953-z.


Rehabilitation in multiple sclerosis: Commentary on the recent AAN systematic review.

Haselkorn JK, Hughes C, Rae-Grant A, Jung Henson L, Bever CT, Lo AC, Brown TR, Kraft GH, Gronseth G, Armstrong MJ, Narayanaswami P.

Neurol Clin Pract. 2017 Jun;7(3):189-190. doi: 10.1212/01.CPJ.0000520916.56328.f5. No abstract available.


Introducing the Axon Registry: An opportunity to improve quality of neurologic care.

Sigsbee B, Goldenberg JN, Bever CT Jr, Schierman B, Jones LK Jr.

Neurology. 2016 Nov 22;87(21):2254-2258. Epub 2016 Sep 30.


SIRT1 and NAD+ precursors: Therapeutic targets in multiple sclerosis a review.

Nimmagadda VK, Makar TK, Chandrasekaran K, Sagi AR, Ray J, Russell JW, Bever CT Jr.

J Neuroimmunol. 2017 Mar 15;304:29-34. doi: 10.1016/j.jneuroim.2016.07.007. Epub 2016 Jul 17. Review.


Tribute to John F. Kurtzke, MD, FACP, FAAN: 1926-2015.

Bever CT Jr, Wallin MT.

Mult Scler. 2016 Mar;22(3):267-8. doi: 10.1177/1352458516632382. No abstract available.


TrkB agonist, 7,8-dihydroxyflavone, reduces the clinical and pathological severity of a murine model of multiple sclerosis.

Makar TK, Nimmagadda VK, Singh IS, Lam K, Mubariz F, Judge SI, Trisler D, Bever CT Jr.

J Neuroimmunol. 2016 Mar 15;292:9-20. doi: 10.1016/j.jneuroim.2016.01.002. Epub 2016 Jan 6.


A Clinically Relevant Method of Analyzing Continuous Change in Robotic Upper Extremity Chronic Stroke Rehabilitation.

Massie CL, Du Y, Conroy SS, Krebs HI, Wittenberg GF, Bever CT, Whitall J.

Neurorehabil Neural Repair. 2016 Sep;30(8):703-12. doi: 10.1177/1545968315620301. Epub 2015 Dec 14.


Summary of comprehensive systematic review: Rehabilitation in multiple sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Haselkorn JK, Hughes C, Rae-Grant A, Henson LJ, Bever CT, Lo AC, Brown TR, Kraft GH, Getchius T, Gronseth G, Armstrong MJ, Narayanaswami P.

Neurology. 2015 Nov 24;85(21):1896-903. doi: 10.1212/WNL.0000000000002146. Review.


Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis.

Makar TK, Gerzanich V, Nimmagadda VK, Jain R, Lam K, Mubariz F, Trisler D, Ivanova S, Woo SK, Kwon MS, Bryan J, Bever CT, Simard JM.

J Neuroinflammation. 2015 Nov 18;12:210. doi: 10.1186/s12974-015-0432-3.


Practice improvement requires more than guidelines and quality measures.

Sigsbee B, Bever CT Jr, Jones LK Jr.

Neurology. 2016 Jan 12;86(2):188-93. doi: 10.1212/WNL.0000000000002116. Epub 2015 Oct 30. Review.


RGC-32 as a potential biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis.

Kruszewski AM, Rao G, Tatomir A, Hewes D, Tegla CA, Cudrici CD, Nguyen V, Royal W 3rd, Bever CT Jr, Rus V, Rus H.

Exp Mol Pathol. 2015 Dec;99(3):498-505. doi: 10.1016/j.yexmp.2015.09.007. Epub 2015 Sep 25.


VHA Multiple Sclerosis Surveillance Registry and its similarities to other contemporary multiple sclerosis cohorts.

Culpepper WJ, Wallin MT, Magder LS, Perencevich E, Royal W, Bradham DD, Cutter G, Bever CT.

J Rehabil Res Dev. 2015;52(3):263-72. doi: 10.1682/JRRD.2014.07.0172.


Quality measurement: It's here to stay.

Cheng EM, Sanders AE, Cohen AB, Bever CT Jr.

Neurol Clin Pract. 2014 Oct;4(5):441-446.


Cell-based delivery of brain-derived neurotrophic factor in experimental allergic encephalomyelitis.

Makar TK, Nimmagadda VK, Trisler D, Bever CT Jr.

J Interferon Cytokine Res. 2014 Aug;34(8):641-7. doi: 10.1089/jir.2013.0160. Epub 2014 Mar 6. Review.


Quality measures for neurologists: Financial and practice implications.

Cohen AB, Sanders AE, Swain-Eng RJ, Gjorvad G, Tonn ST, Bever CT Jr, Cheng EM.

Neurol Clin Pract. 2013 Feb;3(1):44-51.


Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets.

Nimmagadda VK, Bever CT, Vattikunta NR, Talat S, Ahmad V, Nagalla NK, Trisler D, Judge SI, Royal W 3rd, Chandrasekaran K, Russell JW, Makar TK.

J Immunol. 2013 May 1;190(9):4595-607. doi: 10.4049/jimmunol.1202584. Epub 2013 Apr 1.


Hematopoietic progenitors express myelin basic protein and ensheath axons in Shiverer brain.

Goolsby J, Makar T, Dhib-Jalbut S, Bever CT Jr, Pessac B, Trisler D.

J Neuroimmunol. 2013 Apr 15;257(1-2):13-20. doi: 10.1016/j.jneuroim.2013.01.004. Epub 2013 Feb 1.


Use of engineered bone marrow stem cells to deliver brain derived neurotrophic factor under the control of a tetracycline sensitive response element in experimental allergic encephalomyelitis.

Makar TK, Nimmagadda VK, Patibandla GK, Le T, Judge SI, Trisler D, Bever CT.

J Neuroimmunol. 2012 Nov 15;252(1-2):1-15. doi: 10.1016/j.jneuroim.2012.07.005. Epub 2012 Aug 17.


Adult hematopoietic progenitors are multipotent in chimeric mice.

Pessac B, Nimmagadda VK, Makar T, Fishman PS, Bever CT Jr, Trisler D.

C R Biol. 2012 Jul;335(7):454-62. doi: 10.1016/j.crvi.2012.05.005. Epub 2012 Jun 29.


Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study.

Yadav V, Bourdette DN, Bowen JD, Lynch SG, Mattson D, Preiningerova J, Bever CT Jr, Simon J, Goldstein A, Burrows GG, Offner H, Ferro AJ, Vandenbark AA.

Autoimmune Dis. 2012;2012:954739. doi: 10.1155/2012/954739. Epub 2012 Apr 5.


Retinal neural progenitors express topographic map markers.

Goolsby J, Atamas M, Rollor S, Asanuma D, Schuh R, Makar T, Fishman PS, Bever CT Jr, Trisler D.

Neurochem Int. 2012 Nov;61(6):859-65. doi: 10.1016/j.neuint.2012.02.010. Epub 2012 Feb 15.


Effect of gravity on robot-assisted motor training after chronic stroke: a randomized trial.

Conroy SS, Whitall J, Dipietro L, Jones-Lush LM, Zhan M, Finley MA, Wittenberg GF, Krebs HI, Bever CT.

Arch Phys Med Rehabil. 2011 Nov;92(11):1754-61. doi: 10.1016/j.apmr.2011.06.016. Epub 2011 Aug 17.


An economic analysis of robot-assisted therapy for long-term upper-limb impairment after stroke.

Wagner TH, Lo AC, Peduzzi P, Bravata DM, Huang GD, Krebs HI, Ringer RJ, Federman DG, Richards LG, Haselkorn JK, Wittenberg GF, Volpe BT, Bever CT, Duncan PW, Siroka A, Guarino PD.

Stroke. 2011 Sep;42(9):2630-2. doi: 10.1161/STROKEAHA.110.606442. Epub 2011 Jul 14.


Measurement of passive ankle stiffness in subjects with chronic hemiparesis using a novel ankle robot.

Roy A, Krebs HI, Bever CT, Forrester LW, Macko RF, Hogan N.

J Neurophysiol. 2011 May;105(5):2132-49. doi: 10.1152/jn.01014.2010. Epub 2011 Feb 23.


Quality improvement in neurology: AAN epilepsy quality measures: Report of the Quality Measurement and Reporting Subcommittee of the American Academy of Neurology.

Fountain NB, Van Ness PC, Swain-Eng R, Tonn S, Bever CT Jr; American Academy of Neurology Epilepsy Measure Development Panel and the American Medical Association-Convened Physician Consortium for Performance Improvement Independent Measure Development Process.

Neurology. 2011 Jan 4;76(1):94-9. doi: 10.1212/WNL.0b013e318203e9d1.


Quality improvement in neurology: AAN Parkinson disease quality measures: report of the Quality Measurement and Reporting Subcommittee of the American Academy of Neurology.

Cheng EM, Tonn S, Swain-Eng R, Factor SA, Weiner WJ, Bever CT Jr; American Academy of Neurology Parkinson Disease Measure Development Panel.

Neurology. 2010 Nov 30;75(22):2021-7. doi: 10.1212/WNL.0b013e3181ff96dd.


Role of professionalism in improving the patient-centeredness, timeliness, and equity of neurological care.

Bever CT Jr, Franklin GM, Kaufman JM, Esper GJ.

Arch Neurol. 2010 Nov;67(11):1386-90. doi: 10.1001/archneurol.2010.278. No abstract available.


Practice issues in neurology: point of care online resources.

Desai T, Bever CT Jr.

Continuum (Minneap Minn). 2010 Oct;16(5 Multiple Sclerosis):238-42. doi: 10.1212/01.CON.0000389953.50594.9e. No abstract available.


Quality indicators for multiple sclerosis.

Cheng EM, Crandall CJ, Bever CT Jr, Giesser B, Haselkorn JK, Hays RD, Shekelle P, Vickrey BG.

Mult Scler. 2010 Aug;16(8):970-80. doi: 10.1177/1352458510372394. Epub 2010 Jun 18.


Robot-assisted therapy for long-term upper-limb impairment after stroke.

Lo AC, Guarino PD, Richards LG, Haselkorn JK, Wittenberg GF, Federman DG, Ringer RJ, Wagner TH, Krebs HI, Volpe BT, Bever CT Jr, Bravata DM, Duncan PW, Corn BH, Maffucci AD, Nadeau SE, Conroy SS, Powell JM, Huang GD, Peduzzi P.

N Engl J Med. 2010 May 13;362(19):1772-83. doi: 10.1056/NEJMoa0911341. Epub 2010 Apr 16. Erratum in: N Engl J Med. 2011 Nov 3;365(18):1749.


Sustained-release fampridine for multiple sclerosis.

Bever CT, Judge SI.

Expert Opin Investig Drugs. 2009 Jul;18(7):1013-24. doi: 10.1517/13543780903002082. Review. Erratum in: Expert Opin Investig Drugs. 2009 Aug;18(8):1241.


Multicenter randomized trial of robot-assisted rehabilitation for chronic stroke: methods and entry characteristics for VA ROBOTICS.

Lo AC, Guarino P, Krebs HI, Volpe BT, Bever CT, Duncan PW, Ringer RJ, Wagner TH, Richards LG, Bravata DM, Haselkorn JK, Wittenberg GF, Federman DG, Corn BH, Maffucci AD, Peduzzi P.

Neurorehabil Neural Repair. 2009 Oct;23(8):775-83. doi: 10.1177/1545968309338195. Epub 2009 Jun 18.


The effect of repeated measurements using an upper extremity robot on healthy adults.

Finley MA, Dipietro L, Ohlhoff J, Whitall J, Krebs HI, Bever CT.

J Appl Biomech. 2009 May;25(2):103-10.


10 questions about 4-aminopyridine and the treatment of multiple sclerosis.

Bever CT Jr.

Neurologist. 2009 May;15(3):161-2. doi: 10.1097/NRL.0b013e3181679be5. No abstract available.


Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle.

Makar TK, Bever CT, Singh IS, Royal W, Sahu SN, Sura TP, Sultana S, Sura KT, Patel N, Dhib-Jalbut S, Trisler D.

J Neuroimmunol. 2009 May 29;210(1-2):40-51. doi: 10.1016/j.jneuroim.2009.02.017. Epub 2009 Apr 10.


Teleneurology in patients with multiple sclerosis: EDSS ratings derived remotely and from hands-on examination.

Kane RL, Bever CT, Ehrmantraut M, Forte A, Culpepper WJ, Wallin MT.

J Telemed Telecare. 2008;14(4):190-4. doi: 10.1258/jtt.2008.070904.


Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis.

Makar TK, Trisler D, Bever CT, Goolsby JE, Sura KT, Balasubramanian S, Sultana S, Patel N, Ford D, Singh IS, Gupta A, Valenzuela RM, Dhib-Jalbut S.

J Neuroimmunol. 2008 May 30;196(1-2):67-81. doi: 10.1016/j.jneuroim.2008.02.014. Epub 2008 May 8.


Invited article: Neurology and quality improvement: an introduction.

Bever CT, Holloway RG, Iverson DJ, Dubinsky RM, Richardson RM, Sheffield JK, Wang DZ, Franklin GM, Miyasaki JM, Tonn ST, Stevens JC.

Neurology. 2008 Apr 29;70(18):1636-40. doi: 10.1212/01.wnl.0000310989.84987.88. No abstract available.


Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis.

Makar TK, Trisler D, Sura KT, Sultana S, Patel N, Bever CT.

J Neurol Sci. 2008 Jul 15;270(1-2):70-6. doi: 10.1016/j.jns.2008.02.011. Epub 2008 Apr 18.


Potassium channel blockers and openers as CNS neurologic therapeutic agents.

Judge SI, Smith PJ, Stewart PE, Bever CT Jr.

Recent Pat CNS Drug Discov. 2007 Nov;2(3):200-28. Review.


Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology.

Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, Krupp L, Gronseth G, Bever CT Jr; Quality Standards Subcommittee of the American Academy of Neurology.

Neurology. 2007 Jul 3;69(1):91-102. Epub 2007 May 23. Erratum in: Neurology. 2008 Apr 1;70(14):1223.


Robotic upper-limb neurorehabilitation in chronic stroke patients.

Macclellan LR, Bradham DD, Whitall J, Volpe B, Wilson PD, Ohlhoff J, Meister C, Hogan N, Krebs HI, Bever CT Jr.

J Rehabil Res Dev. 2005 Nov-Dec;42(6):717-22.


Short-duration robotic therapy in stroke patients with severe upper-limb motor impairment.

Finley MA, Fasoli SE, Dipietro L, Ohlhoff J, Macclellan L, Meister C, Whitall J, Macko R, Bever CT Jr, Krebs HI, Hogan N.

J Rehabil Res Dev. 2005 Sep-Oct;42(5):683-92.


Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment.

Judge SI, Bever CT Jr.

Pharmacol Ther. 2006 Jul;111(1):224-59. Epub 2006 Feb 9. Review.


Hematopoietic progenitors express neural genes.

Goolsby J, Marty MC, Heletz D, Chiappelli J, Tashko G, Yarnell D, Fishman PS, Dhib-Jalbut S, Bever CT Jr, Pessac B, Trisler D.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14926-31. Epub 2003 Nov 21.

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