Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 403


Persistent Left Superior Vena Cava (PLSVC) with a Connection to the Azygos System: Case Report and Clinical Implications.

Moody AE, Moody CE, Beutler BD, Koci MM.

Case Rep Anesthesiol. 2019 Aug 5;2019:5390272. doi: 10.1155/2019/5390272. eCollection 2019.


Osteoma Cutis Associated with Nevus Sebaceus: Case Report and Review of Cutaneous Osteoma-associated Skin Tumors (COASTs).

Azzam MJ, Beutler BD, Calame A, Erickson CP, Cohen PR.

Cureus. 2019 Jun 20;11(6):e4959. doi: 10.7759/cureus.4959.


Research Techniques Made Simple: Forward Genetic Screening to Uncover Genes Involved in Skin Biology.

McAlpine W, Russell J, Murray AR, Beutler B, Turer E.

J Invest Dermatol. 2019 Sep;139(9):1848-1853.e1. doi: 10.1016/j.jid.2019.04.013.


Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.

Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B.

Nat Immunol. 2019 Aug 19. doi: 10.1038/s41590-019-0464-4. [Epub ahead of print]


YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.

Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, Evans RM, Brenner DA, Saltiel AR, Beutler B, Schnabl B.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15184-15193. doi: 10.1073/pnas.1904360116. Epub 2019 Jul 9.


A Rare Presentation of Drug-induced Liver Injury with Fluticasone and Vilanterol Inhaler Use.

Rishi M, Wagner A, Ulanja M, Beutler BD, Singh K.

Cureus. 2019 Jun 18;11(6):e4933. doi: 10.7759/cureus.4933.


Racial Disparity in Incidence and Survival for Gastrointestinal Stromal Tumors (GISTs): an Analysis of SEER Database.

Ulanja MB, Rishi M, Beutler BD, Konam KG, Ambika S, Hinojosa T, Djankpa FT, Yang W, Gullapalli N.

J Racial Ethn Health Disparities. 2019 Oct;6(5):1035-1043. doi: 10.1007/s40615-019-00605-9. Epub 2019 Jun 18.


An inverted appendix found on routine colonoscopy: A case report with discussion of imaging findings.

Tran C, Sakioka J, Nguyen E, Beutler BD, Hsu J.

Radiol Case Rep. 2019 May 30;14(8):952-955. doi: 10.1016/j.radcr.2019.05.022. eCollection 2019 Aug.


Influence of race and geographic setting on the management of gastric adenocarcinoma.

Ulanja MB, Beutler BD, Rishi M, Konam KG, Zell SC, Patterson DR, Ambika S, Gullapalli N.

J Surg Oncol. 2019 Aug;120(2):270-279. doi: 10.1002/jso.25503. Epub 2019 May 18.


Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice.

Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, Moresco EMY, Turer EE, Beutler B.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11380-11389. doi: 10.1073/pnas.1901407116. Epub 2019 May 16.


LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, Li X, Tang M, Sun Q, Yu L, Murray AR, Moresco EMY, Beutler B.

Science. 2019 May 10;364(6440). pii: eaau0812. doi: 10.1126/science.aau0812.


Colon Cancer Sidedness, Presentation, and Survival at Different Stages.

Ulanja MB, Rishi M, Beutler BD, Sharma M, Patterson DR, Gullapalli N, Ambika S.

J Oncol. 2019 Feb 21;2019:4315032. doi: 10.1155/2019/4315032. eCollection 2019.


Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim.

Su L, Wang Y, Wang J, Mifune Y, Morin MD, Jones BT, Moresco EMY, Boger DL, Beutler B, Zhang H.

J Med Chem. 2019 Mar 28;62(6):2938-2949. doi: 10.1021/acs.jmedchem.8b01583. Epub 2019 Mar 13.


A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis.

Turer EE, San Miguel M, Wang KW, McAlpine W, Ou F, Li X, Tang M, Zang Z, Wang J, Hayse B, Evers B, Zhan X, Russell J, Beutler B.

Dis Model Mech. 2018 Dec 18;11(12). pii: dmm035451. doi: 10.1242/dmm.035451.


Colorectal Cancer Presentation and Survival in Young Individuals: A Retrospective Cohort Study.

Ulanja MB, Beutler BD, Rishi M, Ogala C, Patterson DR, Gullapalli N, Ambika S.

Cancers (Basel). 2018 Nov 28;10(12). pii: E472. doi: 10.3390/cancers10120472.


Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.

McAlpine W, Sun L, Wang KW, Liu A, Jain R, San Miguel M, Wang J, Zhang Z, Hayse B, McAlpine SG, Choi JH, Zhong X, Ludwig S, Russell J, Zhan X, Choi M, Li X, Tang M, Moresco EMY, Beutler B, Turer E.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11523-E11531. doi: 10.1073/pnas.1814753115. Epub 2018 Nov 15.


One-day oral polyethylene glycol based cleanout is effective for pre-colonoscopy preparation in children.

Kumar AS, Beutler BL, Attard TM.

BMC Gastroenterol. 2018 Nov 7;18(1):170. doi: 10.1186/s12876-018-0895-7.


The class I myosin MYO1D binds to lipid and protects against colitis.

McAlpine W, Wang KW, Choi JH, San Miguel M, McAlpine SG, Russell J, Ludwig S, Li X, Tang M, Zhan X, Choi M, Wang T, Bu CH, Murray AR, Moresco EMY, Turer EE, Beutler B.

Dis Model Mech. 2018 Sep 27;11(9). pii: dmm035923. doi: 10.1242/dmm.035923.


Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists.

Morin MD, Wang Y, Jones BT, Mifune Y, Su L, Shi H, Moresco EMY, Zhang H, Beutler B, Boger DL.

J Am Chem Soc. 2018 Oct 31;140(43):14440-14454. doi: 10.1021/jacs.8b09223. Epub 2018 Oct 16.


Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice.

Wang Y, Su L, Morin MD, Jones BT, Mifune Y, Shi H, Wang KW, Zhan X, Liu A, Wang J, Li X, Tang M, Ludwig S, Hildebrand S, Zhou K, Siegwart DJ, Moresco EMY, Zhang H, Boger DL, Beutler B.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8698-E8706. doi: 10.1073/pnas.1809232115. Epub 2018 Aug 27.


B-1a Cell Development in Splenectomized Neonatal Mice.

Pedersen GK, Li X, Khoenkhoen S, Ádori M, Beutler B, Karlsson Hedestam GB.

Front Immunol. 2018 Jul 30;9:1738. doi: 10.3389/fimmu.2018.01738. eCollection 2018.


Gastrointestinal Bleed from Erosive Gastritis and Duodenitis: A Sentinel Event of Invasive Lobular Carcinoma of the Breast and a Diagnostic Dilemma.

Ulanja MB, Taha M, Al-Mashhadani A, Beutler BD, Al-Tekreeti M, Elliot C, Ambika S.

Cureus. 2018 Jun 7;10(6):e2757. doi: 10.7759/cureus.2757.


Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.

Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Chérasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.

Nat Commun. 2018 May 23;9(1):2041. doi: 10.1038/s41467-018-04324-3.


Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.

Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE.

J Clin Invest. 2018 Mar 1;128(3):1178-1189. doi: 10.1172/JCI97702. Epub 2018 Feb 19.


Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database.

Wang T, Bu CH, Hildebrand S, Jia G, Siggs OM, Lyon S, Pratt D, Scott L, Russell J, Ludwig S, Murray AR, Moresco EMY, Beutler B.

Nat Commun. 2018 Jan 30;9(1):441. doi: 10.1038/s41467-017-02806-4.


Altered Marginal Zone B Cell Selection in the Absence of IκBNS.

Ádori M, Pedersen GK, Ádori C, Erikson E, Khoenkhoen S, Stark JM, Choi JH, Dosenovic P, Karlsson MCI, Beutler B, Karlsson Hedestam GB.

J Immunol. 2018 Jan 15;200(2):775-787. doi: 10.4049/jimmunol.1700791. Epub 2017 Dec 8.


Angiokeratoma of the Glans Penis.

Beutler BD, Cohen PR.

Skinmed. 2017 Oct 1;15(5):343-347. eCollection 2017.


Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.

Pollard KM, Escalante GM, Huang H, Haraldsson KM, Hultman P, Christy JM, Pawar RD, Mayeux JM, Gonzalez-Quintial R, Baccala R, Beutler B, Theofilopoulos AN, Kono DH.

J Immunol. 2017 Dec 1;199(11):3739-3747. doi: 10.4049/jimmunol.1700332. Epub 2017 Oct 20.


The ESRP1-GPR137 axis contributes to intestinal pathogenesis.

Mager LF, Koelzer VH, Stuber R, Thoo L, Keller I, Koeck I, Langenegger M, Simillion C, Pfister SP, Faderl M, Genitsch V, Tcymbarevich I, Juillerat P, Li X, Xia Y, Karamitopoulou E, Lyck R, Zlobec I, Hapfelmeier S, Bruggmann R, McCoy KD, Macpherson AJ, Müller C, Beutler B, Krebs P.

Elife. 2017 Oct 4;6. pii: e28366. doi: 10.7554/eLife.28366.


HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections.

Sun L, Jiang Z, Acosta-Rodriguez VA, Berger M, Du X, Choi JH, Wang J, Wang KW, Kilaru GK, Mohawk JA, Quan J, Scott L, Hildebrand S, Li X, Tang M, Zhan X, Murray AR, La Vine D, Moresco EMY, Takahashi JS, Beutler B.

J Exp Med. 2017 Nov 6;214(11):3263-3277. doi: 10.1084/jem.20161630. Epub 2017 Oct 2.


An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue.

Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B.

Sci Rep. 2017 Sep 15;7(1):11717. doi: 10.1038/s41598-017-10343-9.


Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5.

Zhang D, Tomisato W, Su L, Sun L, Choi JH, Zhang Z, Wang KW, Zhan X, Choi M, Li X, Tang M, Castro-Perez JM, Hildebrand S, Murray AR, Moresco EMY, Beutler B.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5197-E5206. doi: 10.1073/pnas.1705312114. Epub 2017 Jun 12.


Reconstruction of the Mouse Inflammasome System in HEK293T Cells.

Shi H, Murray A, Beutler B.

Bio Protoc. 2016 Nov 5;6(21). pii: e1986. doi: 10.21769/BioProtoc.1986.


Polydactylous Transverse Erythronychia: Report of a Patient with Multiple Horizontal Red Bands Affecting the Fingernails.

Chang C, Beutler BD, Cohen PR.

Dermatol Ther (Heidelb). 2017 Jun;7(2):255-262. doi: 10.1007/s13555-017-0177-2. Epub 2017 Mar 4.


Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.

Israel L, Wang Y, Bulek K, Della Mina E, Zhang Z, Pedergnana V, Chrabieh M, Lemmens NA, Sancho-Shimizu V, Descatoire M, Lasseau T, Israelsson E, Lorenzo L, Yun L, Belkadi A, Moran A, Weisman LE, Vandenesch F, Batteux F, Weller S, Levin M, Herberg J, Abhyankar A, Prando C, Itan Y, van Wamel WJB, Picard C, Abel L, Chaussabel D, Li X, Beutler B, Arkwright PD, Casanova JL, Puel A.

Cell. 2017 Feb 23;168(5):789-800.e10. doi: 10.1016/j.cell.2017.01.039.


IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.

Choi JH, Wang KW, Zhang D, Zhan X, Wang T, Bu CH, Behrendt CL, Zeng M, Wang Y, Misawa T, Li X, Tang M, Zhan X, Scott L, Hildebrand S, Murray AR, Moresco EM, Hooper LV, Beutler B.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1196-E1204. doi: 10.1073/pnas.1621258114. Epub 2017 Jan 30.


Creatine maintains intestinal homeostasis and protects against colitis.

Turer E, McAlpine W, Wang KW, Lu T, Li X, Tang M, Zhan X, Wang T, Zhan X, Bu CH, Murray AR, Beutler B.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1273-E1281. doi: 10.1073/pnas.1621400114. Epub 2017 Jan 30.


Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.

Li X, Maretzky T, Perez-Aguilar JM, Monette S, Weskamp G, Le Gall S, Beutler B, Weinstein H, Blobel CP.

J Cell Sci. 2017 Mar 1;130(5):868-878. doi: 10.1242/jcs.196436. Epub 2017 Jan 19.


Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival.

Viant C, Guia S, Hennessy RJ, Rautela J, Pham K, Bernat C, Goh W, Jiao Y, Delconte R, Roger M, Simon V, Souza-Fonseca-Guimaraes F, Grabow S, Belz GT, Kile BT, Strasser A, Gray D, Hodgkin PD, Beutler B, Vivier E, Ugolini S, Huntington ND.

J Exp Med. 2017 Feb;214(2):491-510. doi: 10.1084/jem.20160869. Epub 2017 Jan 5.


Innate immunity and the new forward genetics.

Beutler B.

Best Pract Res Clin Haematol. 2016 Dec;29(4):379-387. doi: 10.1016/j.beha.2016.10.018. Epub 2016 Oct 21. Review.


Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.

Zhang Z, Turer E, Li X, Zhan X, Choi M, Tang M, Press A, Smith SR, Divoux A, Moresco EM, Beutler B.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6418-E6426. Epub 2016 Oct 5.


K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.

Groß CJ, Mishra R, Schneider KS, Médard G, Wettmarshausen J, Dittlein DC, Shi H, Gorka O, Koenig PA, Fromm S, Magnani G, Ćiković T, Hartjes L, Smollich J, Robertson AAB, Cooper MA, Schmidt-Supprian M, Schuster M, Schroder K, Broz P, Traidl-Hoffmann C, Beutler B, Kuster B, Ruland J, Schneider S, Perocchi F, Groß O.

Immunity. 2016 Oct 18;45(4):761-773. doi: 10.1016/j.immuni.2016.08.010. Epub 2016 Sep 27.


Intravascular papillary endothelial hyperplasia of the vulva: report of a patient with Masson tumor of the vulva and literature review.

Beutler BD, Cohen PR.

Dermatol Online J. 2016 May 15;22(5). pii: 13030/qt0ss9x4vf. Review.


Finding New Components of the Mammalian Immune System.

Beutler B.

Rambam Maimonides Med J. 2016 Jul 28;7(3). doi: 10.5041/RMMJ.10245.


Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo.

Wang JQ, Beutler B, Goodnow CC, Horikawa K.

Blood. 2016 Sep 22;128(12):1604-8. doi: 10.1182/blood-2016-03-708065. Epub 2016 Jul 25.


Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.

Siggs OM, Stockenhuber A, Deobagkar-Lele M, Bull KR, Crockford TL, Kingston BL, Crawford G, Anzilotti C, Steeples V, Ghaffari S, Czibik G, Bellahcene M, Watkins H, Ashrafian H, Davies B, Woods A, Carling D, Yavari A, Beutler B, Cornall RJ.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3706-15. doi: 10.1073/pnas.1607592113. Epub 2016 Jun 14.


Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists.

Morin MD, Wang Y, Jones BT, Su L, Surakattula MM, Berger M, Huang H, Beutler EK, Zhang H, Beutler B, Boger DL.

J Med Chem. 2016 May 26;59(10):4812-30. doi: 10.1021/acs.jmedchem.6b00177. Epub 2016 Apr 25.


Heterozygous Mutation in IκBNS Leads to Reduced Levels of Natural IgM Antibodies and Impaired Responses to T-Independent Type 2 Antigens.

Pedersen GK, Ádori M, Stark JM, Khoenkhoen S, Arnold C, Beutler B, Karlsson Hedestam GB.

Front Immunol. 2016 Mar 1;7:65. doi: 10.3389/fimmu.2016.00065. eCollection 2016.

Supplemental Content

Loading ...
Support Center