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Genetic variation in EPHA contributes to sensitivity to paclitaxel-induced peripheral neuropathy.

Marcath LA, Kidwell KM, Vangipuram K, Gersch CL, Rae JM, Burness ML, Griggs JJ, Van Poznak C, Hayes DF, Lavoie Smith EM, Henry NL, Beutler AS, Hertz DL.

Br J Clin Pharmacol. 2019 Dec 10. doi: 10.1111/bcp.14192. [Epub ahead of print]


Impact of youth sports specialisation on career and task-specific athletic performance: a systematic review following the American Medical Society for Sports Medicine (AMSSM) Collaborative Research Network's 2019 Youth Early Sport Specialisation Summit.

Kliethermes SA, Nagle K, Côté J, Malina RM, Faigenbaum A, Watson A, Feeley B, Marshall SW, LaBella CR, Herman DC, Tenforde A, Beutler AI, Jayanthi N.

Br J Sports Med. 2019 Nov 18. pii: bjsports-2019-101365. doi: 10.1136/bjsports-2019-101365. [Epub ahead of print] Review.


Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial.

Ruddy KJ, Le-Rademacher J, Lacouture ME, Wilkinson M, Onitilo AA, Vander Woude AC, Grosse-Perdekamp MT, Dockter T, Tan AD, Beutler A, Loprinzi CL.

Breast. 2019 Dec;48:89-97. doi: 10.1016/j.breast.2019.09.011. Epub 2019 Sep 19.


Association of Splenic Rupture and Infectious Mononucleosis: A Retrospective Analysis and Review of Return-to-Play Recommendations.

Sylvester JE, Buchanan BK, Paradise SL, Yauger JJ, Beutler AI.

Sports Health. 2019 Nov/Dec;11(6):543-549. doi: 10.1177/1941738119873665. Epub 2019 Sep 24.


Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview.

Chan A, Hertz DL, Morales M, Adams EJ, Gordon S, Tan CJ, Staff NP, Kamath J, Oh J, Shinde S, Pon D, Dixit N, D'Olimpio J, Dumitrescu C, Gobbo M, Kober K, Mayo S, Pang L, Subbiah I, Beutler AS, Peters KB, Loprinzi C, Lustberg MB.

Support Care Cancer. 2019 Oct;27(10):3729-3737. doi: 10.1007/s00520-019-04987-8. Epub 2019 Jul 30. Review.


Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial.

Loprinzi C, Le-Rademacher JG, Majithia N, McMurray RP, O'Neill CR, Bendel MA, Beutler A, Lachance DH, Cheville A, Strick DM, Black DF, Tilburt JC, Smith TJ.

Support Care Cancer. 2019 Jun 17. doi: 10.1007/s00520-019-04881-3. [Epub ahead of print]


Functional Movement Assessments Are Not Associated with Risk of Injury During Military Basic Training.

de la Motte SJ, Clifton DR, Gribbin TC, Beutler AI, Deuster PA.

Mil Med. 2019 Dec 1;184(11-12):e773-e780. doi: 10.1093/milmed/usz118.


Injury and Illness Surveillance During the 2016 Department of Defense Warrior Games: Review of Methods and Results.

Rogers AE, Baker J, Beutler A, Witkop C, Leggit JC.

Mil Med. 2019 Dec 1;184(11-12):e616-e621. doi: 10.1093/milmed/usz063.


Gender-Specific Risk Factor Profiles for Patellofemoral Pain.

Boling MC, Nguyen AD, Padua DA, Cameron KL, Beutler A, Marshall SW.

Clin J Sport Med. 2019 Jan 24. doi: 10.1097/JSM.0000000000000719. [Epub ahead of print]


Unilateral Epidural Targeting of Resiniferatoxin Induces Bilateral Neurolysis of Spinal Nociceptive Afferents.

Unger MD, Pleticha J, Steinauer J, Kanwar R, Diehn F, LaVallee KT, Banck MS, Jones B, Yaksh TL, Maus TP, Beutler AS.

Pain Med. 2019 May 1;20(5):897-906. doi: 10.1093/pm/pny276.


MRI guidance technology development in a large animal model for hyperlocal analgesics delivery to the epidural space and dorsal root ganglion.

Maus TP, Felmlee JP, Unger MD, Beutler AS.

J Neurosci Methods. 2019 Jan 15;312:182-186. doi: 10.1016/j.jneumeth.2018.11.024. Epub 2018 Dec 1.


Response to Letter to the Editor From Mr. Russell Greene of CrossFit Inc.

Raleigh MF, Barrett JP, Jones BD, Beutler AI, Deuster PA, O'Connor FG.

Mil Med. 2018 Nov 1;183(11-12):264-265. doi: 10.1093/milmed/usy239. No abstract available.


Clinical research and the AMSSM Collaborative Research Network.

Kliethermes SA, Beutler AI.

Br J Sports Med. 2019 Feb;53(4):204. doi: 10.1136/bjsports-2018-100330. Epub 2018 Nov 27. No abstract available.


Clinical magnetic resonance-enabled characterization of mono-iodoacetate-induced osteoarthritis in a large animal species.

Unger MD, Murthy NS, Kanwar R, Strand KA, Maus TP, Beutler AS.

PLoS One. 2018 Aug 3;13(8):e0201673. doi: 10.1371/journal.pone.0201673. eCollection 2018.


Musculoskeletal Therapies: Adjunctive Physical Therapy.

Beutler A.

FP Essent. 2018 Jul;470:16-20. Review.


Human interleukin-10 delivered intrathecally by self-complementary adeno-associated virus 8 induces xenogeneic transgene immunity without clinical neurotoxicity in swine.

Unger MD, Pleticha J, Heilmann LF, Newman LK, Maus TP, Beutler AS.

J Gene Med. 2018 Jul;20(7-8):e3026. doi: 10.1002/jgm.3026. Epub 2018 Jun 15.


A Cluster of Exertional Rhabdomyolysis Cases in a ROTC Program Engaged in an Extreme Exercise Program.

Raleigh MF, Barrett JP, Jones BD, Beutler AI, Deuster PA, O'Connor FG.

Mil Med. 2018 Mar 1;183(suppl_1):516-521. doi: 10.1093/milmed/usx159. Erratum in: Mil Med. 2019 Jan 1;184(1-2):57.


Effect of a Lower Extremity Preventive Training Program on Physical Performance Scores in Military Recruits.

Peck KY, DiStefano LJ, Marshall SW, Padua DA, Beutler AI, de la Motte SJ, Frank BS, Martinez JC, Cameron KL.

J Strength Cond Res. 2017 Nov;31(11):3146-3157. doi: 10.1519/JSC.0000000000001792.


Laminotomy for Lumbar Dorsal Root Ganglion Access and Injection in Swine.

Unger MD, Maus TP, Puffer RC, Newman LK, Currier BL, Beutler AS.

J Vis Exp. 2017 Oct 10;(128). doi: 10.3791/56434.


The past and future of 'reported outcomes' in studies on chemotherapy neuropathy.

Beutler AS, Majithia N, Loprinzi CL.

Ann Oncol. 2017 Nov 1;28(11):2631-2632. doi: 10.1093/annonc/mdx520. No abstract available.


Fatal Meningitis in Swine after Intrathecal Administration of Adeno-associated Virus Expressing Syngeneic Interleukin-10.

Unger MD, Pleticha J, Collins JE, Armien AG, Brazzell JL, Newman LK, Heilmann LF, Scholz JA, Maus TP, Beutler AS.

Mol Ther. 2017 Nov 1;25(11):2526-2532. doi: 10.1016/j.ymthe.2017.07.016. Epub 2017 Aug 1.


Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer.

Griffith KA, Zhu S, Johantgen M, Kessler MD, Renn C, Beutler AS, Kanwar R, Ambulos N, Cavaletti G, Bruna J, Briani C, Argyriou AA, Kalofonos HP, Yerges-Armstrong LM, Dorsey SG.

J Pain Symptom Manage. 2017 Nov;54(5):701-706.e1. doi: 10.1016/j.jpainsymman.2017.07.033. Epub 2017 Jul 23.


Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials.

Le-Rademacher J, Kanwar R, Seisler D, Pachman DR, Qin R, Abyzov A, Ruddy KJ, Banck MS, Lavoie Smith EM, Dorsey SG, Aaronson NK, Sloan J, Loprinzi CL, Beutler AS.

Support Care Cancer. 2017 Nov;25(11):3537-3544. doi: 10.1007/s00520-017-3780-y. Epub 2017 Jun 20.


A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I.

Pachman DR, Dockter T, Zekan PJ, Fruth B, Ruddy KJ, Ta LE, Lafky JM, Dentchev T, Le-Lindqwister NA, Sikov WM, Staff N, Beutler AS, Loprinzi CL.

Support Care Cancer. 2017 Nov;25(11):3407-3416. doi: 10.1007/s00520-017-3760-2. Epub 2017 May 27.


A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate.

Smolen JS, Agarwal SK, Ilivanova E, Xu XL, Miao Y, Zhuang Y, Nnane I, Radziszewski W, Greenspan A, Beutler A, Baker D.

Ann Rheum Dis. 2017 May;76(5):831-839. doi: 10.1136/annrheumdis-2016-209831. Epub 2017 Jan 13.


The Interrelationship of Common Clinical Movement Screens: Establishing Population-Specific Norms in a Large Cohort of Military Applicants.

de la Motte SJ, Gribbin TC, Lisman P, Beutler AI, Deuster P.

J Athl Train. 2016 Nov;51(11):897-904. doi: 10.4085/1062-6050-51.9.11. Epub 2016 Nov 10.


Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505).

Pachman DR, Qin R, Seisler D, Smith EM, Kaggal S, Novotny P, Ruddy KJ, Lafky JM, Ta LE, Beutler AS, Wagner-Johnston ND, Staff NP, Grothey A, Dougherty PM, Cavaletti G, Loprinzi CL.

Support Care Cancer. 2016 Dec;24(12):5059-5068. Epub 2016 Aug 18.


Prevention and treatment of exercise related leg pain in young soldiers; a review of the literature and current practice in the Dutch Armed Forces.

Zimmermann WO, Helmhout PH, Beutler A.

J R Army Med Corps. 2017 Apr;163(2):94-103. doi: 10.1136/jramc-2016-000635. Epub 2016 Jul 22. Review.


Future Directions in Pain Management: Integrating Anatomically Selective Delivery Techniques With Novel Molecularly Selective Agents.

Pleticha J, Maus TP, Beutler AS.

Mayo Clin Proc. 2016 Apr;91(4):522-33. doi: 10.1016/j.mayocp.2016.02.015. Review.


Preventing Exertional Death in Military Trainees: Recommendations and Treatment Algorithms From a Multidisciplinary Working Group.

Webber BJ, Casa DJ, Beutler AI, Nye NS, Trueblood WE, O'Connor FG.

Mil Med. 2016 Apr;181(4):311-8. doi: 10.7205/MILMED-D-15-00299. Review.


Scrambler Therapy for the management of chronic pain.

Majithia N, Smith TJ, Coyne PJ, Abdi S, Pachman DR, Lachance D, Shelerud R, Cheville A, Basford JR, Farley D, O'Neill C, Ruddy KJ, Sparadeo F, Beutler A, Loprinzi CL.

Support Care Cancer. 2016 Jun;24(6):2807-14. doi: 10.1007/s00520-016-3177-3. Epub 2016 Apr 4. Review.


The Relationship Between Functional Movement, Balance Deficits, and Previous Injury History in Deploying Marine Warfighters.

de la Motte SJ, Lisman P, Sabatino M, Beutler AI, OʼConnor FG, Deuster PA.

J Strength Cond Res. 2016 Jun;30(6):1619-25. doi: 10.1519/JSC.0000000000000850.


Improving Diagnostic Accuracy and Efficiency of Suspected Bone Stress Injuries.

Nye NS, Covey CJ, Sheldon L, Webber B, Pawlak M, Boden B, Beutler A.

Sports Health. 2016 May/Jun;8(3):278-283. doi: 10.1177/1941738116635558. Review.


Neurotoxicity to DRG neurons varies between rodent strains treated with cisplatin and bortezomib.

Podratz JL, Kulkarni A, Pleticha J, Kanwar R, Beutler AS, Staff NP, Windebank AJ.

J Neurol Sci. 2016 Mar 15;362:131-5. doi: 10.1016/j.jns.2015.12.038. Epub 2015 Dec 28.


Targeted alignment and end repair elimination increase alignment and methylation measure accuracy for reduced representation bisulfite sequencing data.

Baheti S, Kanwar R, Goelzenleuchter M, Kocher JP, Beutler AS, Sun Z.

BMC Genomics. 2016 Feb 27;17:149. doi: 10.1186/s12864-016-2494-8.


The Effects of an Injury Prevention Program on Landing Biomechanics Over Time.

DiStefano LJ, Marshall SW, Padua DA, Peck KY, Beutler AI, de la Motte SJ, Frank BS, Martinez JC, Cameron KL.

Am J Sports Med. 2016 Mar;44(3):767-76. doi: 10.1177/0363546515621270. Epub 2016 Jan 20.


Association of Injury History and Incident Injury in Cadet Basic Military Training.

Kucera KL, Marshall SW, Wolf SH, Padua DA, Cameron KL, Beutler AI.

Med Sci Sports Exerc. 2016 Jun;48(6):1053-61. doi: 10.1249/MSS.0000000000000872.


Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance).

Boora GK, Kanwar R, Kulkarni AA, Abyzov A, Sloan J, Ruddy KJ, Banck MS, Loprinzi CL, Beutler AS.

Cancer Med. 2016 Apr;5(4):631-9. doi: 10.1002/cam4.625. Epub 2016 Jan 14.


National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons.

Majithia N, Temkin SM, Ruddy KJ, Beutler AS, Hershman DL, Loprinzi CL.

Support Care Cancer. 2016 Mar;24(3):1439-47. doi: 10.1007/s00520-015-3063-4. Epub 2015 Dec 19. Review.


The Effectiveness of a 6-Week Intervention Program Aimed at Modifying Running Style in Patients With Chronic Exertional Compartment Syndrome: Results From a Series of Case Studies.

Helmhout PH, Diebal AR, van der Kaaden L, Harts CC, Beutler A, Zimmermann WO.

Orthop J Sports Med. 2015 Mar 24;3(3):2325967115575691. doi: 10.1177/2325967115575691. eCollection 2015 Mar.


Calcium and Magnesium Use for Oxaliplatin-Induced Neuropathy: A Case Study to Assess How Quickly Evidence Translates Into Practice.

Pachman DR, Ruddy K, Sangaralingham LR, Grothey A, Shah ND, Beutler AS, Hubbard JM, Loprinzi CL.

J Natl Compr Canc Netw. 2015 Sep;13(9):1097-101.


Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance).

Pachman DR, Qin R, Seisler DK, Smith EM, Beutler AS, Ta LE, Lafky JM, Wagner-Johnston ND, Ruddy KJ, Dakhil S, Staff NP, Grothey A, Loprinzi CL.

J Clin Oncol. 2015 Oct 20;33(30):3416-22. doi: 10.1200/JCO.2014.58.8533. Epub 2015 Aug 17.


Association of the Charcot-Marie-Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance).

Boora GK, Kulkarni AA, Kanwar R, Beyerlein P, Qin R, Banck MS, Ruddy KJ, Pleticha J, Lynch CA, Behrens RJ, Züchner S, Loprinzi CL, Beutler AS.

J Neurol Sci. 2015 Oct 15;357(1-2):35-40. doi: 10.1016/j.jns.2015.06.056. Epub 2015 Jun 27.


Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.

Boora GK, Kanwar R, Kulkarni AA, Pleticha J, Ames M, Schroth G, Beutler AS, Banck MS.

Cancer Genet. 2015 Jul-Aug;208(7-8):374-81. doi: 10.1016/j.cancergen.2015.04.002. Epub 2015 Apr 14.


The Landing Error Scoring System as a Screening Tool for an Anterior Cruciate Ligament Injury-Prevention Program in Elite-Youth Soccer Athletes.

Padua DA, DiStefano LJ, Beutler AI, de la Motte SJ, DiStefano MJ, Marshall SW.

J Athl Train. 2015 Jun;50(6):589-95. doi: 10.4085/1062-6050-50.1.10. Epub 2015 Mar 26.


Radiographic Progression of Patients With Psoriatic Arthritis Who Achieve Minimal Disease Activity in Response to Golimumab Therapy: Results Through 5 Years of a Randomized, Placebo-Controlled Study.

Kavanaugh A, van der Heijde D, Beutler A, Gladman D, Mease P, Krueger GG, McInnes IB, Helliwell P, Coates LC, Xu S.

Arthritis Care Res (Hoboken). 2016 Feb;68(2):267-74. doi: 10.1002/acr.22576.


Exercise collapse associated with sickle cell trait (ECAST): case report and literature review.

Quattrone RD, Eichner ER, Beutler A, Adams WB, O'Connor FG.

Curr Sports Med Rep. 2015 Mar-Apr;14(2):110-6. doi: 10.1249/JSR.0000000000000137. Review.


Plasticity of DNA methylation in a nerve injury model of pain.

Gölzenleuchter M, Kanwar R, Zaibak M, Al Saiegh F, Hartung T, Klukas J, Smalley RL, Cunningham JM, Figueroa ME, Schroth GP, Therneau TM, Banck MS, Beutler AS.

Epigenetics. 2015;10(3):200-12. doi: 10.1080/15592294.2015.1006493.


RWDD3 and TECTA variants not linked to paclitaxel induced peripheral neuropathy in North American trial Alliance N08C1.

Kulkarni AA, Boora G, Kanwar R, Ruddy KJ, Banck MS, Le-Lindqwister N, Therneau TM, Loprinzi CL, Beutler AS.

Acta Oncol. 2015;54(8):1227-9. doi: 10.3109/0284186X.2014.985388. Epub 2014 Dec 31. No abstract available.


High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs.

Pleticha J, Malkmus SA, Heilmann LF, Veesart SL, Rezek R, Xu Q, Yaksh TL, Beutler AS.

Gene Ther. 2015 Feb;22(2):202-8. doi: 10.1038/gt.2014.96. Epub 2014 Oct 30.

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