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Items: 18

1.

Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells.

Beug ST, Korneluk RG, LaCasse EC.

Mol Cell Oncol. 2019 May 8;6(4):1607456. doi: 10.1080/23723556.2019.1607456. eCollection 2019.

PMID:
31211235
2.

The transcription factor SP3 drives TNF-α expression in response to Smac mimetics.

Beug ST, Cheung HH, Sanda T, St-Jean M, Beauregard CE, Mamady H, Baird SD, LaCasse EC, Korneluk RG.

Sci Signal. 2019 Jan 29;12(566). pii: eaat9563. doi: 10.1126/scisignal.aat9563.

PMID:
30696705
3.

Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression.

Beug ST, Pichette SJ, St-Jean M, Holbrook J, Walker DE, LaCasse EC, Korneluk RG.

Mol Ther Oncolytics. 2018 Jun 21;10:28-39. doi: 10.1016/j.omto.2018.06.002. eCollection 2018 Sep 28.

4.

Publisher Correction: Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma.

Beug ST, Beauregard CE, Healy C, Sanda T, St-Jean M, Chabot J, Walker DE, Mohan A, Earl N, Lun X, Senger DL, Robbins SM, Staeheli P, Forsyth PA, Alain T, LaCasse EC, Korneluk RG.

Nat Commun. 2018 Jul 18;9:16231. doi: 10.1038/ncomms16231.

5.

Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.

Morón-Calvente V, Romero-Pinedo S, Toribio-Castelló S, Plaza-Díaz J, Abadía-Molina AC, Rojas-Barros DI, Beug ST, LaCasse EC, MacKenzie A, Korneluk R, Abadía-Molina F.

PLoS One. 2018 Mar 8;13(3):e0193643. doi: 10.1371/journal.pone.0193643. eCollection 2018.

6.

Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma.

Beug ST, Beauregard CE, Healy C, Sanda T, St-Jean M, Chabot J, Walker DE, Mohan A, Earl N, Lun X, Senger DL, Robbins SM, Staeheli P, Forsyth PA, Alain T, LaCasse EC, Korneluk RG.

Nat Commun. 2017 Feb 15;8. doi: 10.1038/ncomms14278. Erratum in: Nat Commun. 2018 Jul 18;9:16231.

7.

Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model.

Dobson CC, Naing T, Beug ST, Faye MD, Chabot J, St-Jean M, Walker DE, LaCasse EC, Stojdl DF, Korneluk RG, Holcik M.

Oncotarget. 2017 Jan 10;8(2):3495-3508. doi: 10.18632/oncotarget.13849.

8.

Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists.

Beug ST, Conrad DP, Alain T, Korneluk RG, Lacasse EC.

Int J Dev Biol. 2015;59(1-3):141-7. doi: 10.1387/ijdb.150084el. Review.

9.

Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists.

Beug ST, Conrad DP, Alain T, Korneluk RG, Lacasse EC.

Int J Dev Biol. 2015 May 21. [Epub ahead of print]

PMID:
26009240
10.

The inhibitors of apoptosis (IAPs): Over 20 years of research into life and death.

LaCasse EC, Beug ST, Korneluk RG.

Semin Cell Dev Biol. 2015 Mar;39:70-1. doi: 10.1016/j.semcdb.2015.04.002. No abstract available.

PMID:
25910657
11.

Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells.

Beug ST, LaCasse EC, Korneluk RG.

Oncoimmunology. 2014 Apr 29;3:e28541. eCollection 2014.

12.

IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1.

Faye MD, Beug ST, Graber TE, Earl N, Xiang X, Wild B, Langlois S, Michaud J, Cowan KN, Korneluk RG, Holcik M.

Oncogene. 2015 Mar 19;34(12):1532-41. doi: 10.1038/onc.2014.90. Epub 2014 Apr 7.

PMID:
24704827
13.

Smac mimetics and innate immune stimuli synergize to promote tumor death.

Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, Korneluk RG.

Nat Biotechnol. 2014 Feb;32(2):182-90. doi: 10.1038/nbt.2806. Epub 2014 Jan 26.

14.

Modulation of immune signalling by inhibitors of apoptosis.

Beug ST, Cheung HH, LaCasse EC, Korneluk RG.

Trends Immunol. 2012 Nov;33(11):535-45. doi: 10.1016/j.it.2012.06.004. Epub 2012 Jul 24. Review.

PMID:
22836014
15.

SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds.

Cheung HH, St Jean M, Beug ST, Lejmi-Mrad R, LaCasse E, Baird SD, Stojdl DF, Screaton RA, Korneluk RG.

Cell Death Dis. 2011 Apr 14;2:e146. doi: 10.1038/cddis.2011.25.

16.

Processing-dependent trafficking of Sonic hedgehog to the regulated secretory pathway in neurons.

Beug ST, Parks RJ, McBride HM, Wallace VA.

Mol Cell Neurosci. 2011 Mar;46(3):583-96. doi: 10.1016/j.mcn.2010.12.009. Epub 2010 Dec 21.

PMID:
21182949
17.

Smac mimetic compounds potentiate interleukin-1beta-mediated cell death.

Cheung HH, Beug ST, St Jean M, Brewster A, Kelly NL, Wang S, Korneluk RG.

J Biol Chem. 2010 Dec 24;285(52):40612-23. doi: 10.1074/jbc.M110.183616. Epub 2010 Oct 18.

18.

Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.

Dakubo GD, Beug ST, Mazerolle CJ, Thurig S, Wang Y, Wallace VA.

Brain Res. 2008 Sep 4;1228:27-42. doi: 10.1016/j.brainres.2008.06.058. Epub 2008 Jun 24.

PMID:
18625210

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