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Items: 1 to 50 of 257

1.

Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.

Fajgenbaum DC, Langan RA, Sada Japp A, Partridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, Jordan MB, Cohen AD, Krymskaya V, Rubenstein A, Betts MR, Kambayashi T, van Rhee F, Uldrick TS.

J Clin Invest. 2019 Aug 13;130. pii: 126091. doi: 10.1172/JCI126091.

2.

Intensity-Modulated Radiotherapy With a Simultaneous Integrated Boost in Rectal Cancer.

Owens R, Mukherjee S, Padmanaban S, Hawes E, Jacobs C, Weaver A, Betts M, Muirhead R.

Clin Oncol (R Coll Radiol). 2019 Jul 27. pii: S0936-6555(19)30289-4. doi: 10.1016/j.clon.2019.07.009. [Epub ahead of print]

PMID:
31362843
3.

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.

Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E, Hämmerer D.

Brain. 2019 Jul 20. pii: awz193. doi: 10.1093/brain/awz193. [Epub ahead of print]

PMID:
31327002
4.

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals.

Klicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK.

Sci Immunol. 2019 Jul 5;4(37). pii: eaav8995. doi: 10.1126/sciimmunol.aav8995.

PMID:
31278120
5.

T follicular helper cells in human efferent lymph retain lymphoid characteristics.

Vella LA, Buggert M, Manne S, Herati RS, Sayin I, Kuri-Cervantes L, Bukh Brody I, O'Boyle KC, Kaprielian H, Giles JR, Nguyen S, Muselman A, Antel JP, Bar-Or A, Johnson ME, Canaday DH, Naji A, Ganusov VV, Laufer TM, Wells AD, Dori Y, Itkin MG, Betts MR, Wherry EJ.

J Clin Invest. 2019 Jul 2;129(8):3185-3200. doi: 10.1172/JCI125628. eCollection 2019 Jul 2.

6.

Response to the letter to the editor on "an indirect treatment comparison of the efficacy of patisiran and tafamidis for the treatment of hereditary transthyretin-mediated amyloidosis with polyneuropathy".

Lin H, Agarwal S, Betts M, Fahrbach K, Chitnis M, Polydefkis M.

Expert Opin Pharmacother. 2019 May 24:1-2. doi: 10.1080/14656566.2019.1620987. [Epub ahead of print] No abstract available.

PMID:
31124741
7.

Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B.

Chang KM, Traum D, Park JJ, Ho S, Ojiro K, Wong DK, Wahed AS, Terrault NA, Khalili M, Sterling RK, Janssen HLA, Shuhart MC, Lau DT, Roberts LR, Johnson GS, Kaplan DE, Betts MR, Lee WM, Lok ASF; Hepatitis B Research Network (HBRN).

PLoS Pathog. 2019 Apr 18;15(4):e1007715. doi: 10.1371/journal.ppat.1007715. eCollection 2019 Apr.

8.

Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model.

Brody IB, Calcedo R, Connell MJ, Carnathan DG, Nason M, Lawson BO, Nega MT, Boyd S, Qin Q, Vanderford TH, Wilson JM, Wilson JM, Silvestri G, Betts MR.

Pathog Immun. 2019 Jan 29;4(1):1-20. doi: 10.20411/pai.v4i1.241. eCollection 2019.

9.

Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels.

Betts MJ, Cardenas-Blanco A, Kanowski M, Spottke A, Teipel SJ, Kilimann I, Jessen F, Düzel E.

Alzheimers Dement (Amst). 2019 Mar 27;11:281-285. doi: 10.1016/j.dadm.2019.02.001. eCollection 2019 Dec.

10.

Large species within carnivora are large carnivores.

Wolf C, Betts MG, Levi T, Newsome TM, Ripple WJ.

R Soc Open Sci. 2018 Sep 12;5(9):181228. doi: 10.1098/rsos.181228. eCollection 2018 Sep. No abstract available.

11.

Synergistic effects of climate and land-use change influence broad-scale avian population declines.

Northrup JM, Rivers JW, Yang Z, Betts MG.

Glob Chang Biol. 2019 May;25(5):1561-1575. doi: 10.1111/gcb.14571. Epub 2019 Feb 27.

PMID:
30810257
12.

Rapid growth is a dominant predictor of hepcidin suppression and declining ferritin in Gambian infants.

Armitage AE, Agbla SC, Betts M, Sise EA, Jallow MW, Sambou E, Darboe B, Worwui A, Weinstock GM, Antonio M, Pasricha SR, Prentice AM, Drakesmith H, Darboe MK, Kwambana-Adams BA.

Haematologica. 2019 Aug;104(8):1542-1553. doi: 10.3324/haematol.2018.210146. Epub 2019 Feb 7.

13.

Impacts of the Northwest Forest Plan on forest composition and bird populations.

Phalan BT, Northrup JM, Yang Z, Deal RL, Rousseau JS, Spies TA, Betts MG.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3322-3327. doi: 10.1073/pnas.1813072116. Epub 2019 Feb 4.

14.

Comparison of Recommendations and Use of Cardiovascular Risk Equations by Health Technology Assessment Agencies and Clinical Guidelines.

Betts MB, Milev S, Hoog M, Jung H, Milenković D, Qian Y, Tai MH, Kutikova L, Villa G, Edwards C.

Value Health. 2019 Feb;22(2):210-219. doi: 10.1016/j.jval.2018.08.003. Epub 2018 Sep 21. Review.

15.

CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume.

Düzel E, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Betts M, Ziegler G, Chen Y, Dobisch L, Bittner D, Glanz W, Reuter M, Spottke A, Rudolph J, Brosseron F, Buerger K, Janowitz D, Fliessbach K, Heneka M, Laske C, Buchmann M, Nestor P, Peters O, Diesing D, Li S, Priller J, Spruth EJ, Altenstein S, Ramirez A, Schneider A, Kofler B, Speck O, Teipel S, Kilimann I, Dyrba M, Wiltfang J, Bartels C, Wolfsgruber S, Wagner M, Jessen F.

Alzheimers Dement (Amst). 2018 Nov 2;10:782-790. doi: 10.1016/j.dadm.2018.10.003. eCollection 2018.

16.

AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver.

Greig JA, Calcedo R, Kuri-Cervantes L, Nordin JML, Albrecht J, Bote E, Goode T, Chroscinski EA, Bell P, Richman LK, Betts MR, Wilson JM.

Mol Ther Methods Clin Dev. 2018 Dec 5;11:191-201. doi: 10.1016/j.omtm.2018.10.012. eCollection 2018 Dec 14.

17.

Everything in its right place: resident memory CD8+ T cell immunosurveillance of HIV infection.

Buggert M, Japp AS, Betts MR.

Curr Opin HIV AIDS. 2019 Mar;14(2):93-99. doi: 10.1097/COH.0000000000000523.

PMID:
30520744
18.

An indirect treatment comparison of the efficacy of patisiran and tafamidis for the treatment of hereditary transthyretin-mediated amyloidosis with polyneuropathy.

Planté-Bordeneuve V, Lin H, Gollob J, Agarwal S, Betts M, Fahrbach K, Chitnis M, Polydefkis M.

Expert Opin Pharmacother. 2019 Mar;20(4):473-481. doi: 10.1080/14656566.2018.1554648. Epub 2018 Dec 12. Review.

PMID:
30489166
19.

In vivo visualization of age-related differences in the locus coeruleus.

Liu KY, Acosta-Cabronero J, Cardenas-Blanco A, Loane C, Berry AJ, Betts MJ, Kievit RA, Henson RN, Düzel E; Cam-CAN, Howard R, Hämmerer D.

Neurobiol Aging. 2019 Feb;74:101-111. doi: 10.1016/j.neurobiolaging.2018.10.014. Epub 2018 Oct 20.

20.

The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool.

Dias J, Boulouis C, Gorin JB, van den Biggelaar RHGA, Lal KG, Gibbs A, Loh L, Gulam MY, Sia WR, Bari S, Hwang WYK, Nixon DF, Nguyen S, Betts MR, Buggert M, Eller MA, Broliden K, Tjernlund A, Sandberg JK, Leeansyah E.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11513-E11522. doi: 10.1073/pnas.1812273115. Epub 2018 Nov 15.

21.

Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue.

Steblyanko M, Anikeeva N, Buggert M, Betts MR, Sykulev Y.

J Vis Exp. 2018 Jul 30;(137). doi: 10.3791/58143.

22.

Herbicides and herbivory interact to drive plant community and crop-tree establishment.

Stokely TD, Verschuyl J, Hagar JC, Betts MG.

Ecol Appl. 2018 Dec;28(8):2011-2023. doi: 10.1002/eap.1777. Epub 2018 Sep 24.

PMID:
30027661
23.

Commentary: Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.

Betts MJ, Ehrenberg AJ, Hämmerer D, Düzel E.

Front Neurosci. 2018 Jun 6;12:401. doi: 10.3389/fnins.2018.00401. eCollection 2018. No abstract available.

24.

Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.

Sci Immunol. 2018 Jun 1;3(24). pii: eaar4526. doi: 10.1126/sciimmunol.aar4526.

25.

Spatial distribution and function of T follicular regulatory cells in human lymph nodes.

Sayin I, Radtke AJ, Vella LA, Jin W, Wherry EJ, Buggert M, Betts MR, Herati RS, Germain RN, Canaday DH.

J Exp Med. 2018 Jun 4;215(6):1531-1542. doi: 10.1084/jem.20171940. Epub 2018 May 16.

26.

Future time perspective: A systematic review and meta-analysis.

Kooij DTAM, Kanfer R, Betts M, Rudolph CW.

J Appl Psychol. 2018 Aug;103(8):867-893. doi: 10.1037/apl0000306. Epub 2018 Apr 23. Review.

PMID:
29683685
27.

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.

Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ.

Sci Transl Med. 2018 Apr 18;10(437). pii: eaar6759. doi: 10.1126/scitranslmed.aar6759.

28.

Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.

Buggert M, Nguyen S, McLane LM, Steblyanko M, Anikeeva N, Paquin-Proulx D, Del Rio Estrada PM, Ablanedo-Terrazas Y, Noyan K, Reuter MA, Demers K, Sandberg JK, Eller MA, Streeck H, Jansson M, Nowak P, Sönnerborg A, Canaday DH, Naji A, Wherry EJ, Robb ML, Deeks SG, Reyes-Teran G, Sykulev Y, Karlsson AC, Betts MR.

PLoS Pathog. 2018 Apr 13;14(4):e1006973. doi: 10.1371/journal.ppat.1006973. eCollection 2018 Apr.

29.

The receptor repertoire and functional profile of follicular T cells in HIV-infected lymph nodes.

Wendel BS, Del Alcazar D, He C, Del Río-Estrada PM, Aiamkitsumrit B, Ablanedo-Terrazas Y, Hernandez SM, Ma KY, Betts MR, Pulido L, Huang J, Gimotty PA, Reyes-Terán G, Jiang N, Su LF.

Sci Immunol. 2018 Apr 6;3(22). pii: eaan8884. doi: 10.1126/sciimmunol.aan8884.

30.

Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions.

Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M.

JCI Insight. 2018 Apr 5;3(7). pii: 98487. doi: 10.1172/jci.insight.98487. eCollection 2018 Apr 5.

31.

Locus coeruleus integrity in old age is selectively related to memories linked with salient negative events.

Hämmerer D, Callaghan MF, Hopkins A, Kosciessa J, Betts M, Cardenas-Blanco A, Kanowski M, Weiskopf N, Dayan P, Dolan RJ, Düzel E.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2228-2233. doi: 10.1073/pnas.1712268115. Epub 2018 Feb 12.

32.

Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells.

Noyan K, Nguyen S, Betts MR, Sönnerborg A, Buggert M.

Front Immunol. 2018 Jan 22;9:19. doi: 10.3389/fimmu.2018.00019. eCollection 2018.

33.

HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue.

Reuter MA, Del Rio Estrada PM, Buggert M, Petrovas C, Ferrando-Martinez S, Nguyen S, Sada Japp A, Ablanedo-Terrazas Y, Rivero-Arrieta A, Kuri-Cervantes L, Gunzelman HM, Gostick E, Price DA, Koup RA, Naji A, Canaday DH, Reyes-Terán G, Betts MR.

Cell Rep. 2017 Dec 19;21(12):3458-3470. doi: 10.1016/j.celrep.2017.11.075.

34.

The "jack-in-the-box" stamens of Heliconia wagneriana (Heliconiaceae).

Gannon DG, Kormann UG, Hadley AS, Betts MG, Jones FA.

Ecology. 2018 Feb;99(2):488-490. doi: 10.1002/ecy.2042. Epub 2017 Dec 4. No abstract available.

PMID:
29205316
35.

Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children's health in India and Sub-Saharan Africa.

Chandak GR, Silver MJ, Saffari A, Lillycrop KA, Shrestha S, Sahariah SA, Di Gravio C, Goldberg G, Tomar AS, Betts M, Sajjadi S, Acolatse L, James P, Issarapu P, Kumaran K, Potdar RD, Prentice AM, Fall CH.

BMC Nutr. 2017 Oct 30;3. pii: 81. doi: 10.1186/s40795-017-0200-0.

36.

Genetic variants affecting equivalent protein family positions reflect human diversity.

Raimondi F, Betts MJ, Lu Q, Inoue A, Gutkind JS, Russell RB.

Sci Rep. 2017 Oct 6;7(1):12771. doi: 10.1038/s41598-017-12971-7.

37.

No evidence for a link between forest herbicides and offspring sex ratio in a migratory songbird using high-throughput molecular sexing.

Rivers JW, Houtz JL, Betts MG, Horton BM.

Conserv Physiol. 2017 Sep 22;5(1):cox054. doi: 10.1093/conphys/cox054. eCollection 2017.

38.

In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults.

Betts MJ, Cardenas-Blanco A, Kanowski M, Jessen F, Düzel E.

Neuroimage. 2017 Dec;163:150-159. doi: 10.1016/j.neuroimage.2017.09.042. Epub 2017 Sep 22.

PMID:
28943414
39.

Identification of Subsets of Enteroaggregative Escherichia coli Associated with Diarrheal Disease among Under 5 Years of Age Children from Rural Gambia.

Ikumapayi UN, Boisen N, Hossain MJ, Betts M, Lamin M, Saha D, Kwambana-Adams B, Dione M, Adegbola RA, Roca A, Nataro JP, Antonio M.

Am J Trop Med Hyg. 2017 Oct;97(4):997-1004. doi: 10.4269/ajtmh.16-0705. Epub 2017 Aug 18.

40.

Capturing protein communities by structural proteomics in a thermophilic eukaryote.

Kastritis PL, O'Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, Beck M, Gavin AC.

Mol Syst Biol. 2017 Jul 25;13(7):936. doi: 10.15252/msb.20167412.

41.

T-bet-expressing B cells during HIV and HCV infections.

Knox JJ, Kaplan DE, Betts MR.

Cell Immunol. 2017 Nov;321:26-34. doi: 10.1016/j.cellimm.2017.04.012. Epub 2017 Jul 11. Review.

42.

Emotional arousal and recognition memory are differentially reflected in pupil diameter responses during emotional memory for negative events in younger and older adults.

Hämmerer D, Hopkins A, Betts MJ, Maaß A, Dolan RJ, Düzel E.

Neurobiol Aging. 2017 Oct;58:129-139. doi: 10.1016/j.neurobiolaging.2017.06.021. Epub 2017 Jun 30.

PMID:
28734217
43.

Global forest loss disproportionately erodes biodiversity in intact landscapes.

Betts MG, Wolf C, Ripple WJ, Phalan B, Millers KA, Duarte A, Butchart SHM, Levi T.

Nature. 2017 Jul 27;547(7664):441-444. doi: 10.1038/nature23285. Epub 2017 Jul 19.

PMID:
28723892
44.

Corrigendum: Insights into cancer severity from biomolecular interaction mechanisms.

Raimondi F, Singh G, Betts MJ, Apic G, Vukotic R, Andreone P, Stein L, Russell RB.

Sci Rep. 2017 May 3;7:46284. doi: 10.1038/srep46284. No abstract available.

45.

T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.

Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR.

JCI Insight. 2017 Apr 20;2(8). pii: 92943. doi: 10.1172/jci.insight.92943. eCollection 2017 Apr 20.

46.

Systematic identification of phosphorylation-mediated protein interaction switches.

Betts MJ, Wichmann O, Utz M, Andre T, Petsalaki E, Minguez P, Parca L, Roth FP, Gavin AC, Bork P, Russell RB.

PLoS Comput Biol. 2017 Mar 27;13(3):e1005462. doi: 10.1371/journal.pcbi.1005462. eCollection 2017 Mar.

47.

Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.

Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1655-1659. doi: 10.1073/pnas.1617726114. Epub 2017 Jan 30.

48.

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.

Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, Ruiz-Mateos E, Vagios I, Leal M, Ablanedo-Terrazas Y, Rivero A, Gonzalez-Hernandez LA, McDermott AB, Moir S, Reyes-Terán G, Docobo F, Pantaleo G, Douek DC, Betts MR, Estes JD, Germain RN, Mascola JR, Koup RA.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaag2285. doi: 10.1126/scitranslmed.aag2285.

49.

Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.

Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC.

Sci Rep. 2017 Jan 13;7:40354. doi: 10.1038/srep40354.

50.

Reproductive modification in forest plantations: impacts on biodiversity and society.

Strauss SH, Jones KN, Lu H, Petit JD, Klocko AL, Betts MG, Brosi BJ, Fletcher RJ Jr, Needham MD.

New Phytol. 2017 Feb;213(3):1000-1021. doi: 10.1111/nph.14374. Review.

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