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Items: 16

1.

Measuring longitudinal cognition: Individual tests versus composites.

Jonaitis EM, Koscik RL, Clark LR, Ma Y, Betthauser TJ, Berman SE, Allison SL, Mueller KD, Hermann BP, Van Hulle CA, Christian BT, Bendlin BB, Blennow K, Zetterberg H, Carlsson CM, Asthana S, Johnson SC.

Alzheimers Dement (Amst). 2019 Jan 11;11:74-84. doi: 10.1016/j.dadm.2018.11.006. eCollection 2019 Dec.

2.

AD molecular: Imaging tau aggregates with positron emissions tomography.

Betthauser TJ.

Prog Mol Biol Transl Sci. 2019;165:107-138. doi: 10.1016/bs.pmbts.2019.07.007. Epub 2019 Aug 20.

PMID:
31481160
3.

Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife.

Clark LR, Koscik RL, Allison SL, Berman SE, Norton D, Carlsson CM, Betthauser TJ, Bendlin BB, Christian BT, Chin NA, Asthana S, Johnson SC.

Alzheimers Dement. 2019 Mar;15(3):418-428. doi: 10.1016/j.jalz.2018.09.008. Epub 2018 Oct 25.

PMID:
30367828
4.

The use of Centiloids for applying [11C]PiB classification cutoffs across region-of-interest delineation methods.

Tudorascu DL, Minhas DS, Lao PJ, Betthauser TJ, Yu Z, Laymon CM, Lopresti BJ, Mathis CA, Klunk WE, Handen BL, Christian BT, Cohen AD.

Alzheimers Dement (Amst). 2018 Apr 21;10:332-339. doi: 10.1016/j.dadm.2018.03.006. eCollection 2018.

5.

In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand 18F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls.

Betthauser TJ, Cody KA, Zammit MD, Murali D, Converse AK, Barnhart TE, Stone CK, Rowley HA, Johnson SC, Christian BT.

J Nucl Med. 2019 Jan;60(1):93-99. doi: 10.2967/jnumed.118.209650. Epub 2018 May 18.

6.

Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation.

Lao PJ, Handen BL, Betthauser TJ, Cody KA, Cohen AD, Tudorascu DL, Stone CK, Price JC, Johnson SC, Klunk WE, Christian BT.

Brain Imaging Behav. 2019 Apr;13(2):345-353. doi: 10.1007/s11682-018-9888-y.

7.

Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Johnson SC, Klunk WE, Christian BT.

J Alzheimers Dis. 2018;61(2):631-644. doi: 10.3233/JAD-170720.

8.

Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau.

Betthauser TJ, Ellison PA, Murali D, Lao PJ, Barnhart TE, Furumoto S, Okamura N, Johnson SC, Engle JW, Nickles RJ, Christian BT.

Appl Radiat Isot. 2017 Dec;130:230-237. doi: 10.1016/j.apradiso.2017.10.002. Epub 2017 Oct 4.

9.

Human biodistribution and dosimetry of [18F]nifene, an α4β2* nicotinic acetylcholine receptor PET tracer.

Betthauser TJ, Hillmer AT, Lao PJ, Ehlerding E, Mukherjee J, Stone CK, Christian BT.

Nucl Med Biol. 2017 Dec;55:7-11. doi: 10.1016/j.nucmedbio.2017.08.001. Epub 2017 Aug 17.

10.

Human brain imaging of nicotinic acetylcholine α4β2* receptors using [18 F]Nifene: Selectivity, functional activity, toxicity, aging effects, gender effects, and extrathalamic pathways.

Mukherjee J, Lao PJ, Betthauser TJ, Samra GK, Pan ML, Patel IH, Liang C, Metherate R, Christian BT.

J Comp Neurol. 2018 Jan 1;526(1):80-95. doi: 10.1002/cne.24320. Epub 2017 Sep 19.

11.

Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Mailick MR, Klunk WE, Johnson SC, Christian BT.

Alzheimers Dement (Amst). 2017 May 23;9:1-9. doi: 10.1016/j.dadm.2017.05.001. eCollection 2017.

12.

[18 F]Nifene test-retest reproducibility in first-in-human imaging of α4β2* nicotinic acetylcholine receptors.

Lao PJ, Betthauser TJ, Tudorascu DL, Barnhart TE, Hillmer AT, Stone CK, Mukherjee J, Christian BT.

Synapse. 2017 Aug;71(8). doi: 10.1002/syn.21981. Epub 2017 Apr 26.

13.

In Vivo Comparison of Tau Radioligands 18F-THK-5351 and 18F-THK-5317.

Betthauser TJ, Lao PJ, Murali D, Barnhart TE, Furumoto S, Okamura N, Stone CK, Johnson SC, Christian BT.

J Nucl Med. 2017 Jun;58(6):996-1002. doi: 10.2967/jnumed.116.182980. Epub 2016 Nov 10.

14.

Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation.

Racine AM, Koscik RL, Nicholas CR, Clark LR, Okonkwo OC, Oh JM, Hillmer AT, Murali D, Barnhart TE, Betthauser TJ, Gallagher CL, Rowley HA, Dowling NM, Asthana S, Bendlin BB, Blennow K, Zetterberg H, Carlsson CM, Christian BT, Johnson SC.

Alzheimers Dement (Amst). 2016;2:27-38.

15.

The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by carbon 11-labeled Pittsburgh compound B.

Lao PJ, Betthauser TJ, Hillmer AT, Price JC, Klunk WE, Mihaila I, Higgins AT, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Mailick MR, Johnson SC, Handen BL, Christian BT.

Alzheimers Dement. 2016 Apr;12(4):380-90. doi: 10.1016/j.jalz.2015.05.013. Epub 2015 Jun 13.

16.

First-in-human evaluation of 18F-mefway, a PET radioligand specific to serotonin-1A receptors.

Hillmer AT, Wooten DW, Bajwa AK, Higgins AT, Lao PJ, Betthauser TJ, Barnhart TE, Rowley HA, Stone CK, Johnson SC, Mukherjee J, Christian BT.

J Nucl Med. 2014 Dec;55(12):1973-9. doi: 10.2967/jnumed.114.145151. Epub 2014 Nov 13.

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